Sodium zirconium cyclosilicate: all 29 studies that test it

Page 1 of 1. Open to participants first (4), then studies with results posted, then the rest; newest registration first within each.

• The Cardioprotective Effects of Improving Potassium Variability in Maintenance Hemodialysis PatientsNot yet recruitingNCT06736184Phase 4
• Keeping RAASi Treatment With Optimal Potassium ControlRecruitingNCT06578533Phase 3
• A Clinical Trial to Define the Best Strategy for the Management of Heart Failure in Elderly PatientsRecruitingNCT06578078Phase 3
• Sodium Zirconium Cyclosilicate to Allow Liberal Fruit and Vegetable Intake for Patients With CKD Stage 3b and 4RecruitingNCT06365684Phase 4
• Continuing Sodium Zirconium Cyclosilicate (SZC) After Discharge StudyCompletedNCT05347693Phase 4Results posted
• A Study to Evaluate the Effect of Sodium Zirconium Cyclosilicate on Chronic Kidney Disease (CKD) Progression in Participants With CKD and Hyperkalaemia or at Risk of HyperkalaemiaTerminatedNCT05056727Phase 3Results posted
• Study of SZC and Enhanced Nutrition Advice Compared to SoC in Dialysis Patients With HyperkalaemiaTerminatedNCT04997161Phase 4Results posted
• The ORTIZ Study: Optimising RASi Therapy With SZCTerminatedNCT04983979Phase 2Results posted
• Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes)TerminatedNCT04847232Phase 3Results posted
• Study to Assess the Effect of Sodium Zirconium Cyclosilicate on the Pharmacokinetics of Tacrolimus and Cyclosporin in Healthy SubjectsCompletedNCT04788641Phase 1Results posted
• Study of the Effect of SZC on Serum Potassium and Serum Bicarbonate in Patients With Hyperkalemia and Metabolic Acidosis Associated With Chronic Kidney DiseaseTerminatedNCT04727528Phase 3Results posted
• Study to Assess Efficacy and Safety of SZC for the Management of High Potassium in Patients With Symptomatic HFrEF Receiving SpironolactoneCompletedNCT04676646Phase 4Results posted
• Comparison of Potassium Binders in the ERTerminatedNCT04585542Phase 4Results posted
• Reduce Incidence of Pre-Dialysis Hyperkalaemia With Sodium Zirconium Cyclosilicate in Chinese SubjectsCompletedNCT04217590Phase 3Results posted
• Potassium Reduction Initiative to Optimize RAAS Inhibition Therapy With Sodium Zirconium Cyclosilicate in Heart FailureTerminatedNCT03532009Phase 2Results posted
• A Study to Investigate the Safety and Efficacy of ZS in Patients With Hyperkalemia.CompletedNCT03528681Phase 3Results posted
• A Study to Evaluate a Potassium Normalization Treatment Regimen Including Sodium Zirconium Cyclosilicate (ZS) Among Patients With S-K ≥5.8CompletedNCT03337477Phase 2Results posted
• A Study to Test Whether ZS (Sodium Zirconium Cyclosilicate) Can Reduce the Incidence of Increased Blood Potassium Levels Among Dialized Patients.CompletedNCT03303521Phase 3Results posted
• ZS Ph2/3 Dose-response Study in JapanCompletedNCT03127644Phase 2/3Results posted
• A Study to Investigate the Safety and Efficacy of ZS in Patients With HyperkalemiaCompletedNCT02875834Phase 3Results posted
• Open-label Safety and Efficacy of Sodium Zirconium Cyclosilicate for up to 12 MonthsCompletedNCT02163499Phase 3Results posted
• Open-label Safety & Efficacy of ZS (Sodium Zirconium Cyclosilicate)10g qd to Extend Study ZS-004 in Hyperkalemia.CompletedNCT02107092Phase 3Results posted
• Safety & Efficacy of Zirconium Silicate Dosed for 28 Days in Hyperkalemia.CompletedNCT02088073Phase 3Results posted
• SZC Versus SPS for Treatment of Hyperkalemia in Hemodialysis PatientsCompletedNCT06029179Not applicable
• Sodium Zirconium Cyclosilicate Lowers Hyperkalemia After ParathyroidectomyCompletedNCT05382988Phase 3
• Lokelma for RAAS Maximisation in CKD & Heart Failure.CompletedNCT05004363Phase 3
• OPtimizing Aldosterone Receptor Antagonist Therapy by Sodium Zirconium Cyclosilicate in Heart FailureActive, not recruitingNCT04789239Phase 2
• Potassium Binder in CKD Patients (With Hyperkalemia) (DiPo Trial)Status unknownNCT04727840Phase 1
• A Safety and Pharmacodynamic Study of Healthy Chinese Subjects Administered Sodium Zirconium Cyclosilicate (ZS)CompletedNCT03283267Phase 1

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