Semaglutide: all 426 studies that test it

Page 3 of 5. Open to participants first (151), then studies with results posted, then the rest; newest registration first within each.

• Effects of Semaglutide in HIV-Associated LipohypertrophyActive, not recruitingNCT04019197Phase 2Results posted
• A Research Study Comparing a New Medicine Oral Semaglutide to Sitagliptin in People With Type 2 DiabetesCompletedNCT04017832Phase 3Results posted
• A Study Comparing the Injection Site Pain Experience After the Injection of 2 Different Solutions of Semaglutide With 2 Different Injection Pens, a Compound for the Treatment of Type 2 Diabetes and ObesityCompletedNCT04007107Phase 2Results posted
• A Research Study to Compare Two Doses of Semaglutide Taken Once Weekly in People With Type 2 DiabetesCompletedNCT03989232Phase 3Results posted
• A Research Study on How Semaglutide Works in People With Fatty Liver Disease and Liver DamageCompletedNCT03987451Phase 2Results posted
• Treating PCOS With Semaglutide vs Active Lifestyle InterventionCompletedNCT03919929Phase 2/3Results posted
• A Heart Disease Study of Semaglutide in Patients With Type 2 DiabetesCompletedNCT03914326Phase 3Results posted
• A Research Study to See How Semaglutide Works Compared to Placebo in People With Type 2 Diabetes and Chronic Kidney DiseaseCompletedNCT03819153Phase 3Results posted
• STEP 6: Research Study Investigating How Well Semaglutide Works in People Living With Overweight or ObesityCompletedNCT03811574Phase 3Results posted
• Two-year Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or ObesityCompletedNCT03693430Phase 3Results posted
• A Research Study to Compare Semaglutide to Insulin Aspart, When Taken Together With Metformin and Insulin Glargine, in People With Type 2 DiabetesCompletedNCT03689374Phase 3Results posted
• Research Study to Look at How Well Semaglutide is at Lowering Weight When Taken Together With an Intensive Lifestyle ProgramCompletedNCT03611582Phase 3Results posted
• Long Term Comparative Effectiveness of Once Weekly Semaglutide Versus Standard of Care in a Real World Adult US Population With Type 2 Diabetes - a Randomized Pragmatic TrialCompletedNCT03596450Phase 4Results posted
• Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or ObesityCompletedNCT03574597Phase 3Results posted
• Research Study Investigating How Well Semaglutide Works in People With Type 2 Diabetes Suffering From Overweight or ObesityCompletedNCT03552757Phase 3Results posted
• Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or ObesityCompletedNCT03548987Phase 3Results posted
• STEP 1: Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or ObesityCompletedNCT03548935Phase 3Results posted
• Research Study Comparing a New Medicine Semaglutide to Liraglutide in People With Type 2 DiabetesCompletedNCT03191396Phase 3Results posted
• Efficacy and Safety of Semaglutide Versus Canagliflozin as add-on to Metformin in Subjects With Type 2 DiabetesCompletedNCT03136484Phase 3Results posted
• Efficacy and Safety of Semaglutide Once-weekly Versus Placebo as add-on to SGLT-2i in Subjects With Type 2 Diabetes MellitusCompletedNCT03086330Phase 3Results posted
• Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin in Subjects With Type 2 Diabetes (SUSTAIN - CHINA MRCT)CompletedNCT03061214Phase 3Results posted
• Efficacy and Safety of Oral Semaglutide Versus Placebo in Subjects With Type 2 Diabetes Mellitus Treated With InsulinCompletedNCT03021187Phase 3Results posted
• Dose-response, Safety and Efficacy of Oral Semaglutide Versus Placebo and Versus Liraglutide, All as Monotherapy in Japanese Subjects With Type 2 DiabetesCompletedNCT03018028Phase 3Results posted
• Safety and Efficacy of Oral Semaglutide Versus Dulaglutide Both in Combination With One OAD (Oral Antidiabetic Drug) in Japanese Subjects With Type 2 DiabetesCompletedNCT03015220Phase 3Results posted
• Investigation of Efficacy and Safety of Three Dose Levels of Subcutaneous Semaglutide Once Daily Versus Placebo in Subjects With Non-alcoholic Steatohepatitis.CompletedNCT02970942Phase 2Results posted
• Efficacy and Safety of Oral Semaglutide Versus Placebo in Subjects With Type 2 Diabetes Mellitus Treated With Diet and Exercise OnlyCompletedNCT02906930Phase 3Results posted
• Efficacy and Safety of Oral Semaglutide Versus Liraglutide and Versus Placebo in Subjects With Type 2 Diabetes MellitusCompletedNCT02863419Phase 3Results posted
• Efficacy and Safety of Oral Semaglutide Versus Empagliflozin in Subjects With Type 2 Diabetes MellitusCompletedNCT02863328Phase 3Results posted
• Efficacy and Safety of Oral Semaglutide Using a Flexible Dose Adjustment Based on Clinical Evaluation Versus Sitagliptin in Subjects With Type 2 Diabetes Mellitus.CompletedNCT02849080Phase 3Results posted
• Efficacy and Safety of Oral Semaglutide Versus Placebo in Subjects With Type 2 Diabetes and Moderate Renal ImpairmentCompletedNCT02827708Phase 3Results posted
• A Trial Investigating the Cardiovascular Safety of Oral Semaglutide in Subjects With Type 2 DiabetesCompletedNCT02692716Phase 3Results posted
• Efficacy and Safety of Semaglutide Versus Dulaglutide as add-on to Metformin in Subjects With Type 2 Diabetes.CompletedNCT02648204Phase 3Results posted
• Efficacy and Long-term Safety of Oral Semaglutide Versus Sitagliptin in Subjects With Type 2 DiabetesCompletedNCT02607865Phase 3Results posted
• Dose-finding of Semaglutide Administered Subcutaneously Once Daily Versus Placebo and Liraglutide in Subjects With Type 2 DiabetesCompletedNCT02461589Phase 2Results posted
• Investigation of Safety and Efficacy of Once-daily Semaglutide in Obese Subjects Without Diabetes MellitusCompletedNCT02453711Phase 2Results posted
• Efficacy and Safety of Semaglutide Once-weekly Versus Placebo as add-on to Basal Insulin Alone or Basal Insulin in Combination With Metformin in Subjects With Type 2 DiabetesCompletedNCT02305381Phase 3Results posted
• A Trial Comparing the Safety and Efficacy of Semaglutide Once Weekly Versus Sitagliptin Once Daily in Japanese Subjects With Type 2 DiabetesCompletedNCT02254291Phase 3Results posted
• A Trial Comparing the Safety and Efficacy of Semaglutide Once Weekly in Monotherapy or in Combination With One OAD in Japanese Subjects With Type 2 DiabetesCompletedNCT02207374Phase 3Results posted
• Efficacy and Safety of Semaglutide Once Weekly Versus Insulin Glargine Once Daily as add-on to Metformin With or Without Sulphonylurea in Insulin-naïve Subjects With Type 2 DiabetesCompletedNCT02128932Phase 3Results posted
• Efficacy and Safety of Semaglutide Once-weekly Versus Placebo in Drug-naïve Subjects With Type 2 DiabetesCompletedNCT02054897Phase 3Results posted
• Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin and/or TZD in Subjects With Type 2 DiabetesCompletedNCT01930188Phase 3Results posted
• Multiple Dose Trial Examining Dose Range, Escalation and Efficacy of Oral Semaglutide in Subjects With Type 2 DiabetesCompletedNCT01923181Phase 2Results posted
• Efficacy and Safety of Semaglutide Once-weekly Versus Exenatide ER 2.0 mg Once-weekly as add-on to 1-2 Oral Antidiabetic Drugs (OADs) in Subjects With Type 2 DiabetesCompletedNCT01885208Phase 3Results posted
• Trial to Evaluate Cardiovascular and Other Long-term Outcomes With Semaglutide in Subjects With Type 2 DiabetesCompletedNCT01720446Phase 3Results posted
• A Randomised Controlled Clinical Trial in Type 2 Diabetes Comparing Semaglutide to Placebo and LiraglutideCompletedNCT00696657Phase 2Results posted
• ELITE: Deep Profiling and Algorithmic Polytherapy to Map Individual Response in Healthy AgingCompletedNCT07871799Phase 2
• Weekly GLP-1 Receptor Agonists in Obese Individuals Without DiabetesCompletedNCT07834398Phase 3
• Comparative Study of Different Weekly GLP-1 Receptor Agonists Among Diabetic and Non-Diabetic Patients: Clinical TrialCompletedNCT07820111Phase 3
• Efficacy of Once Weekly Semaglutide in Patients With Type 2 Diabetes: a Non Randomized Clinical TrialCompletedNCT07732218Phase 4
• A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With ObesityActive, not recruitingNCT07639021Phase 2
• Effects of Dapagliflozin, Semaglutide, and Their Combination in Heart Failure Patients With Prosthetic Heart ValvesCompletedNCT07610174Phase 2
• Beta Cell Function in Type 2 Diabetes: Differential Effects of SGLT2 Inhibitors and GLIP-Receptor AgonistsActive, not recruitingNCT07325435Phase 4
• A Research Study to See if Two Different Formulations of Oral Semaglutide Are Equally Safe and Effective in Reducing the Blood Sugar Level in Japanese People With Type 2 DiabetesCompletedNCT07271251Phase 3
• Semaglutide (SEMA) for Alcohol Use Disorder (AUD) After Metabolic and Bariatric Surgery (MBS)Active, not recruitingNCT07223983Phase 1
• A Study to See the Effect of NNC0194-0499 Alone or in Combination With Semaglutide on Blood Sugar Control in People Living With Type 1 DiabetesActive, not recruitingNCT07087795Phase 1
• Investigation of GLP1-Receptor Agonists in Men With Prostate Cancer Taking Androgen Deprivation TherapyActive, not recruitingNCT06908694Phase 4
• Semaglutide in Women With Polycystic Ovary Syndrome and ObesityCompletedNCT06896981Phase 2/3
• Sequential Therapy Anti-obesitY Medication With Muscle Preservation for Weight Loss and MaintEnance: A PragmAtic Randomized CoNtrolled Trial (STAY-LEAN Trial)Active, not recruitingNCT06854614Phase 4
• Impact of Pharmacogenetic-Guided Treatment on Type 2 Diabetes.CompletedNCT06851962Phase 4
• A Study of a Novel Precision Medicine Approach For ObesityActive, not recruitingNCT06814938Phase 4
• Bariatric Surgery vs. Semaglutide vs. TirzepatideActive, not recruitingNCT06803888Phase 4
• Effects of Long-Acting GLP-1 (Glucagon-like Peptide-1) or Dual Incretin (GLP-1 and GIP [Glucose-dependent Insulinotropic Peptide]) Modulation on Gastric Motor FunctionsActive, not recruitingNCT06801015Phase 4
• A Research Study to Look Into the Long-term Effect on Weight Loss of CagriSema in People With ObesityActive, not recruitingNCT06780449Phase 3
• Efficacy and Safety of Empagliflozin or Semaglutide in Overweight/Obese Patients With Type 1 DiabetesCompletedNCT06762314Phase 2
• A Study of Enlicitide Decanoate (MK-0616) and Semaglutide in Healthy Adult Participants (MK-0616-023)CompletedNCT06699329Phase 1
• Evaluation Of Semaglutide in Adults With Cocaine Use Disorder With and Without HIVActive, not recruitingNCT06691243Phase 2
• Semaglutide and Intestinal Iron AbsorptionCompletedNCT06629688Not applicable
• Glucagon-like Peptide-1 Receptor Agnoists for the Assessment of Adrenal FunctionCompletedNCT06608433Not applicable
• Study to Evaluate the Effect on Obesity of QW Nimacimab and QW Nimacimab Co-administered With Semaglutide vs PlaceboActive, not recruitingNCT06577090Phase 2
• STEP TEENS Weight Maintenance: A Research Study on How Well Semaglutide Helps Teenagers With Excess Body Weight to Lose Weight and Maintain Weight LossActive, not recruitingNCT06571383Phase 4
• Effect of Oral Semaglutide on Epicardial and Pericoronary Adipose Tissues in Type 2 Diabetes After Myocardial InfarctionStatus unknownNCT06557811Phase 4
• A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or BothCompletedNCT06534411Phase 3
• Open Randomized Study of Comparative Pharmacokinetics and Biosimilarity of GP40221 (GEROPHARM LLC, Russia) and Ozempic®.CompletedNCT06497049Phase 1
• The Effects of Semaglutide vs Testosterone Replacement Therapy on Functional Hypogonadism and Sperm Quality in Men With Type 2 Diabetes Mellitus and ObesityCompletedNCT06489457Phase 3
• Effect of Semaglutide on the Psoriatic Lesions in Patients With Type 2 Diabetes MellitusCompletedNCT06475586Phase 4
• The Effects of Semaglutide on Body Composition and Performance in Military PersonnelWithdrawnNCT06468748Phase 4
• Effects of NNC0194-0499, Cagrilintide, and Semaglutide Alone or in Combinations on Liver Damage and Alcohol Use in People With Alcohol-related Liver DiseaseCompletedNCT06409130Phase 2
• Investigating How CagriSema, Semaglutide and Cagrilintide Regulate Insulin Effects in the Body of People With Type 2 DiabetesCompletedNCT06403761Phase 1
• The Effect of Weekly Semaglutide Treatment on Energy ExpenditureCompletedNCT06390501Not applicable
• A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose WeightCompletedNCT06388187Phase 3
• Semaglutide and Cognition in Healthy VolunteersCompletedNCT06363487Not applicable
• A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Diet and ExerciseCompletedNCT06323174Phase 3
• A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Once-daily Basal Insulin With or Without MetforminCompletedNCT06323161Phase 3
• A Study to Test if Trevogrumab or Trevogrumab With Garetosmab When Taken With Semaglutide is Safe and How Well They Work in Adult Patients With Obesity for Weight Loss, Fat Loss, and Lean Mass PreservationActive, not recruitingNCT06299098Phase 2
• A Research Study to See How Well New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Levels in People With Type 2 Diabetes (T2D), Compared to Daily Insulin Glargine (COMBINE 4)CompletedNCT06269107Phase 3
• A Study of How CagriSema Works on Appetite in People With Excess Body WeightCompletedNCT06267092Phase 1
• Semaglutide and Polycystic Ovarian Syndrome: an Emerging Treatment StrategyWithdrawnNCT06222437Phase 1
• A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 InhibitorCompletedNCT06221969Phase 3
• A Research Study to Look at How CagriSema Influences Food Intake, Appetite and Emptying of the Stomach in People With Excess Body WeightCompletedNCT06207877Phase 1
• DUTCH Weight Control in Atrial Fibrillation StudyActive, not recruitingNCT06184633Phase 4
• Efficacy and Safety of Semaglutide Injection (HD1916) in Patients With Type 2 Diabetes MellitusCompletedNCT06161844Phase 3
• A Research Study to See How Well CagriSema Compared to Tirzepatide Helps People With Obesity Lose WeightCompletedNCT06131437Phase 3
• A Research Study to See if Kidney Damage in People With Chronic Kidney Disease and Type 2 Diabetes Living With Overweight or Obesity Can be Reduced by CagriSema Compared to Semaglutide, Cagrilintide and PlaceboCompletedNCT06131372Phase 2
• A Research Study Looking at New Protein-based Tablets in Healthy Men - Oral Formulation IIICompletedNCT06097390Phase 1
• Research Study to Compare Semaglutide Tablets With Empagliflozin or Metformin Tablets in People With Type 2 DiabetesWithdrawnNCT06083675Phase 3
• A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 InhibitorCompletedNCT06065540Phase 3
• The Effect of Oral Semaglutide on Bone Turnover in Patients With T2D: a Randomized Placebo-controlled Clinical TrialActive, not recruitingNCT06050577Phase 2
• DIALYSIS-TIR StudyActive, not recruitingNCT06042153Phase 4
• The Effect of an Anti-obesity Drug, Semaglutide, as Treatment in New-onset Idiopathic Intracranial Hypertension (IIH) Compared to Standard Weight Management (Dietician) With Regards to Change in Weight and Intracranial PressureCompletedNCT06027567Phase 4
• Semaglutide Therapy for Alcohol Reduction (STAR)Active, not recruitingNCT06015893Phase 2

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