Roflumilast: all 117 studies that test it
Page 1 of 2. Open to participants first (16), then studies with results posted, then the rest; newest registration first within each.
- Comparative Effectiveness of Roflumilast and Azithromycin in Reducing Exacerbations in Severe Chronic Obstructive Pulmonary Disease ( COPD ) Patients With Chronic Bronchitis PhenotypeNot yet recruitingNCT07795086Phase 4
- An Open Label Trial to Evaluate Efficacy and Safety of Roflumilast 0.3% Cream for Chronic Plaque and Nail PsoriasisRecruitingNCT07725822Phase 4
- Safety and Efficacy of Roflumilast Foam 0.3% in Adolescent and Adult Subjects With Hidradenitis SuppurativaRecruitingNCT07689188Phase 2
- An Open-label, Single Center Study Evaluating the Safety and Efficacy of Roflumilast Foam 0.3% in Subjects With Cutaneous Adverse Events Due to Checkpoint InhibitorsNot yet recruitingNCT07639840Phase 2
- Effect of Roflumilast as Add-On Therapy in Rheumatoid ArthritisRecruitingNCT07632846Phase 2
- Effect of Roflumilast and Desloratadine as Add-On Therapy in Patients With Rheumatoid ArthritisRecruitingNCT07566351Phase 2
- Obtaining Descriptive Classifications of Pruritus and Assessing Change in Pruritus Over Time in Atopic Dermatitis Patients Using Topical Roflumilast Cream.RecruitingNCT07560618Phase 4
- EFFICACY OF ROFLUMILAST IN THE TREATMENT OF FLEXURAL AND/OR GENITAL PSORIASIS: A RANDOMIZED CONTROLLED TRIAL.Not yet recruitingNCT07543640Phase 2
- Utilization of a Microdevice for Psoriasis and Atopic DermatitisNot yet recruitingNCT07352566Phase 4
- Evaluation of Efficacy and Safety of Oral Roflumilast for Treatment of Moderate to Severe Atopic Dermatitis in Patients Aged 12 Years and Older: A Pilot StudyRecruitingNCT07297602Phase 2
- The Safety and Efficacy of Roflumilast Foam in HSRecruitingNCT07263230Phase 2
- A Pilot Study to Assess How Safe and Effective Oral Roflumilast is for Treating Moderate to Severe Psoriasis in AdultsRecruitingNCT07233291Phase 2
- Loncastuximab and Roflumilast Added to R-CHOP (Lo-(Rituximab and Roflumilast) RR-CHOP) for Naïve High-Risk Diffuse Large B-cell Lymphoma (DLBCL)RecruitingNCT06977711Phase 1
- Roflumilast as an Adjunct to Antidepressants in Major Depressive Disorder PatientsRecruitingNCT06860958Phase 3
- Visualization of Topical Zoryve vs. Vehicle Using Line Field Optical Coherence Tomography in Healthy SkinRecruitingNCT06440473Phase 4
- Efficacy of Roflumilast in Prevention of Peripheral NeuropathyNot yet recruitingNCT05884281Phase 1/2
- Bioequivalence Study of Two Treatments for the Treatment of Plaque PsoriasisCompletedNCT05763082Phase 3Results posted
- Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis (Integument-PED)CompletedNCT04845620Phase 3Results posted
- Open Label Extension Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic DermatitisCompletedNCT04804605Phase 3Results posted
- Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis (INTEGUMENT-II)CompletedNCT04773600Phase 3Results posted
- Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic DermatitisCompletedNCT04773587Phase 3Results posted
- Maximal Usage Pharmacokinetics and Safety of ARQ-151 in Children With Plaque Psoriasis (ARQ-151-216)CompletedNCT04746911Phase 2Results posted
- Maximal Usage Pharmacokinetics and Safety of ARQ-151 in Children With Plaque Psoriasis (ARQ-151-215)CompletedNCT04655313Phase 2Results posted
- Open-Label Extension Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque PsoriasisCompletedNCT04286607Phase 3Results posted
- Twin Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque PsoriasisCompletedNCT04211389Phase 3Results posted
- Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque PsoriasisCompletedNCT04211363Phase 3Results posted
- Safety and Efficacy of ARQ-151 Cream in Adolescents and Adults With Atopic DermatitisCompletedNCT03916081Phase 2Results posted
- Long-Term Safety of ARQ-151 Cream in Adult Subjects With Chronic Plaque PsoriasisCompletedNCT03764475Phase 2Results posted
- The Safety, Efficacy and Pharmacokinetics of ARQ-151 Cream in Subjects With Chronic Plaque PsoriasisCompletedNCT03638258Phase 2Results posted
- Trial of Roflumilast in Asthma Management (TRIM)CompletedNCT03532490Phase 2Results posted
- Safety, Pharmacokinetics and Efficacy of ARQ-151 Cream in Adults With Mild to Moderate Chronic Plaque PsoriasisCompletedNCT03392168Phase 1/2Results posted
- The Effectiveness of Roflumilast in Improving Mucociliary Clearance in Patients With COPD and Chronic BronchitisCompletedNCT03073798Phase 4Results posted
- Enhancement of Corticosteroid Efficacy in COPDCompletedNCT02340520Phase 3Results posted
- Evaluation of Tolerability and Pharmacokinetics of Roflumilast, 250μg and 500μg, as add-on to Standard COPD Treatment to Treat Severe COPDCompletedNCT02165826Phase 3Results posted
- Effect of Roflumilast on Airway Blood Flow as an Expression of Airway Inflammation in COPDCompletedNCT02097992Phase 1/2Results posted
- Roflumilast Plus Antipsychotics Proof of Mechanism Study in SchizophreniaCompletedNCT02079844Phase 1Results posted
- Roflumilast and Donepezil to Reverse Scopolamine Induced Cognitive Deficits in Healthy AdultsCompletedNCT02051335Phase 1Results posted
- Effects of Roflumilast in Hospitalized Chronic Obstructive Pulmonary Disease( COPD) on Mortality and Re-hospitalizationCompletedNCT01973998Phase 3Results posted
- Phase 0/1 Biomarker and Pharmacodynamic Study of Roflumilast in Patients With Advanced B-Cell Hematologic Malignancies (CTRC# 13-0013)CompletedNCT01888952Early Phase 1Results posted
- Effects of Roflumilast on Insulin and Blood Sugar Levels in Prediabetic Overweight and Obese IndividualsCompletedNCT01862029Phase 1/2Results posted
- Topical Roflumilast in Adults With Atopic DermatitisCompletedNCT01856764Phase 2Results posted
- Roflumilast Plus Montelukast in Adults With Severe AsthmaCompletedNCT01765192Phase 2Results posted
- Roflumilast on Markers of Bone Metabolism and Endothelial Function in COPDCompletedNCT01745848Phase 4Results posted
- Safety and Efficacy of Roflumilast and Pioglitazone in Treating Adults With Nonalcoholic SteatoHepatitisTerminatedNCT01703260Phase 2Results posted
- Roflumilast Plus Alogliptin Proof-of-Mechanism Study in Type2 DiabetesCompletedNCT01664624Phase 1Results posted
- Effects of ROFLUMILAST on Subclinical Atherosclerosis in Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT01630200Phase 4Results posted
- A Placebo-controlled Trial of Daliresp on Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT01572948Not applicableResults posted
- Trial to Assess the Anti-inflammatory Effects of Roflumilast in Chronic Obstructive Pulmonary DiseaseCompletedNCT01509677Phase 3Results posted
- Effect of Roflumilast at Acute Exacerbations of Chronic Obstructive Pulmonary DiseaseTerminatedNCT01473758Phase 2Results posted
- Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Fixed Dose Combinations of Long-acting β2-agonist (LABA) and Inhaled Corticosteroid (ICS)CompletedNCT01443845Phase 4Results posted
- Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Fixed Combinations of Long-acting β2-agonists (LABA) and Inhaled Glucocorticosteroid (ICS)CompletedNCT01329029Phase 4Results posted
- A Chronic Obstructive Pulmonary Disease (COPD) Trial Investigating Roflumilast on Safety and Effectiveness in China, Hong Kong and Singapore:CompletedNCT01313494Phase 3Results posted
- Effect of Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Tiotropium: The HELIOS Study (BY217/M2-128)CompletedNCT00424268Phase 3Results posted
- Effect of Roflumilast on Lung Function in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Salmeterol: The EOS Study (BY217/M2-127)CompletedNCT00313209Phase 3Results posted
- Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (COPD): The HERMES Study (BY217/M2-125)CompletedNCT00297115Phase 3Results posted
- Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (COPD): The AURA Study (BY217/M2-124)CompletedNCT00297102Phase 3Results posted
- Evaluation of the Efficacy and Safety of Oral Roflumilast Versus Intralesional Corticosteroids Injection (ILCs) in the Treatment of Alopecia AreataCompletedNCT07174011Phase 4
- A Study for Evaluating Safety & Efficacy of Topical Roflumilast 0.3% Foam in Hidradenitis SuppurativaCompletedNCT07077902Phase 2
- Safety Study of Roflumilast Cream 0.05% in Infants Aged 3 Months to Less Than 2 Years With Atopic DermatitisCompletedNCT06998056Phase 2
- Evaluating the Efficacy and Safety of Roflumilast in Patients with NASHCompletedNCT06677788Phase 2
- Efficacy and Safety of Roflumilast Cream 0.3% in Subjects With Plaque Psoriasis: a Phase 3 StudyCompletedNCT06648772Phase 3
- Efficacy and Safety of Roflumilast Cream in Subjects With Atopic DermatitisCompletedNCT06631170Phase 3
- Roflumilast and TMS Motor PlasticityActive, not recruitingNCT06457191Phase 1
- Clinical Trial of Roflumilast Added to Standard ChemoimmunotherapyWithdrawnNCT05796271Phase 1
- Roflumilast Versus Methotrexate in PsoriasisCompletedNCT05684744Phase 2/3
- Role of Roflumilast in Ulcerative ColitisCompletedNCT05684484Phase 4
- Treatment of Chronic Hand Eczema With Oral Roflumilast (HERO)CompletedNCT05682859Phase 4
- Evaluating the Neurophysiologic and Clinical Effects of Single Dose Drug ChallengeActive, not recruitingNCT05418049Phase 2
- Clinical Study Evaluating the Safety and Efficacy of Roflumilast in Type 2 Diabetic Patients With Diabetic NeuropathyCompletedNCT05369793Phase 3
- Evaluation of the Safety and Efficacy of Topical Roflumilast Cream in the Treatment of Facial Papulopustular RosaceaCompletedNCT05278624Phase 2
- Roflumilast to Treat Cognitive Sequela After StrokeCompletedNCT04854811Phase 2
- The Possible Effects of Roflumilast on Obesity Related DisordersCompletedNCT04800172Phase 3
- Possible Role of Roflumilast in Diabetic NephropathyStatus unknownNCT04755946Phase 3
- The Phosphodiesterase 4 Inhibitor Roflumilast as an Adjunct to Antidepressants in Major Depressive Disorder PatientsWithdrawnNCT04751071Phase 1/2
- Roflumilast as add-on Therapy in Early Cases of ARDSCompletedNCT04744090Phase 2
- Cognitive Effects of Roflumilast in (a)MCI and Mild Dementia PatientsStatus unknownNCT04658654Phase 2
- Efficacy of Roflumilast in the Treatment of PsoriasisCompletedNCT04549870Phase 2
- Roflumilast TMS-EEG PlasticityWithdrawnNCT04369547Phase 1
- Roflumilast in Non-CF Bronchiectasis Study (2019)CompletedNCT04322929Phase 2
- Maximal Usage Pharmacokinetics and Safety of ARQ-151 in Adolescents and Adults With Chronic Plaque PsoriasisCompletedNCT04279119Phase 1
- Pharmacokinetics (PK), Safety, Efficacy and Maximal Use PK of ARQ-151 in Adolescents/Children With Mild/Moderate EczemaCompletedNCT04156191Phase 1
- Efficacy of Roflumilast on Exacerbations in Patients With Non-cystic Fibrosis BronchiectasisCompletedNCT04122547Phase 3
- Phosphodiesterase 4 Inhibitor, Roflumilast, and the Effects of Inhibition in Severe AsthmaTerminatedNCT04108377Phase 1
- Assessment of Early Outcomes of Roflumilast in Patients With Non Cystic Fibrosis BronchiectasisStatus unknownNCT04090294Early Phase 1
- Roflumilast or Azithromycin to Prevent COPD Exacerbations TrialCompletedNCT04069312Phase 3
- Effect of Roflumilast on Quality of Life, Lung Function and Mucus Properties in Patients With BronchiectasisStatus unknownNCT03988816Phase 2
- Study of Roflumilast in Combination With Standard Chemotherapy for High-risk Diffuse Large B-cell LymphomaCompletedNCT03458546Phase 1
- Roflumilast in Non-CF Bronchiectasis StudyCompletedNCT03428334Phase 2
- A Multicenter Randomized Double-blind Clinical Study Evaluated the Safety, Pharmacokinetic and Pharmacodynamic Characteristics of Roflumilast in COPD PatientsTerminatedNCT02671942Phase 2
- Evaluation of the Effect of Roflumilast in Hyperinflated COPD Patients Using Functional Respiratory ImagingTerminatedNCT02451540Phase 2
- PDE-4 Inhibitor Roflumilast and GLP-1 Agonist Liraglutide in Polycystic Ovary SyndromeCompletedNCT02187250Phase 4
- PDE-4 Inhibitor Roflumilast and Polycystic Ovary SyndromeCompletedNCT02037672Phase 4
- Strategy to Improve Adherence of RoflumilastStatus unknownNCT02018432Phase 4
- Use of Roflumilast to Prevent Exacerbations in Fibrotic Sarcoidosis Patients (REFS)Status unknownNCT01830959Phase 4
- Impact of Roflumilast on Visceral Adiposity and Metabolic Profile in Chronic Obstructive Pulmonary DiseaseTerminatedNCT01701934Phase 2
- Phase2, Single Group, Open Clinical Trial to Evaluate the Efficacy and Safety of Roflumilast in Symptomatic Bronchiectasis PatientsStatus unknownNCT01580748Phase 2
- Evaluation With CT Scan of Possible Changes in Airways After Treatment With Daxas® in Severe Chronic Obstructive Pulmonary Disease PatientsCompletedNCT01480661Phase 4
- Roflumilast and CognitionCompletedNCT01433666Phase 2
- A Study to Evaluate the Effect of Roflumilast on Airway Inflammation and Function Following Allergen Challenge in Subjects With Allergic AsthmaCompletedNCT01365533Phase 2
- Pharmacokinetic Study of Single and Repeated Dose of Roflumilast 500 µg , in Healthy Chinese SubjectsCompletedNCT01354782Phase 1