Ripretinib clinical trials
Also written DCC-2618.
How each study uses ripretinib is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Approvals
The first approval found in each region, with its record
- United States
- 15 May 2020 · QINLOCK · NDA 213973 (FDA, Drugs@FDA)
- European Union
- 18 Nov 2021 · Qinlock · EMEA/H/C/005614 (EMA)
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
9 studies that test it; most in 2020 (2)
| Year | Studies |
|---|---|
| 2015 | 1 |
| 2018 | 1 |
| 2019 | 1 |
| 2020 | 2 |
| 2021 | 2 |
| 2023 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 9 · Other 0
Deciphera Pharmaceuticals, LLC (6) · Zai Lab (Shanghai) Co., Ltd. (2) · Ono Pharmaceutical Co., Ltd. (1)
Often tested with
Tested in the same studies.
Related medicines
As reviewed, each with the page that says it.
Studies
Open first, then newest update. How each study uses ripretinib is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 9
- Study of DCC-2618 in Patients With GIST After at Least 3 Prior TreatmentsRecruitingPhase 1Ono Pharmaceutical Co., Ltd.NCT07618377Written as DCC-2618
- A Study of Ripretinib vs Sunitinib in Advanced GIST Patients After Treatment With ImatinibActive, not recruitingPhase 3Deciphera Pharmaceuticals, LLCNCT03673501Written as Ripretinib
- A Study to Assess DCC-2618 and Sunitinib in Patients With Advanced GIST After Treatment With ImatinibCompletedPhase 2Zai Lab (Shanghai) Co., Ltd.NCT04633122Written as Ripretinib
- A Study of Ripretinib vs Sunitinib in Patients With Advanced GIST With Specific KIT Exon Mutations Who Were Previously Treated With ImatinibActive, not recruitingPhase 3Deciphera Pharmaceuticals, LLCNCT05734105Written as Ripretinib
- A Study of DCC-2618 (Ripretinib) In Patients With With Advanced Gastrointestinal Stromal Tumors (GIST)CompletedPhase 2Zai Lab (Shanghai) Co., Ltd.NCT04282980Written as DCC-2618
- A Drug-Drug Interaction Study to Evaluate the Effect of Ripretinib on the Pharmacokinetics of a CYP2C8 Probe Substrate in Patients with Advanced GISTCompletedPhase 1Deciphera Pharmaceuticals, LLCNCT04530981Written as Ripretinib
- A Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced MalignanciesCompletedPhase 1Deciphera Pharmaceuticals, LLCNCT02571036Written as DCC-2618
- Phase 3 Study of DCC-2618 vs Placebo in Advanced GIST Patients Who Have Been Treated With Prior Anticancer TherapiesCompletedPhase 3Deciphera Pharmaceuticals, LLCNCT03353753Written as DCC-2618
- Ripretinib in Combination With Binimetinib in Patients With Gastrointestinal Stromal Tumor (GIST)WithdrawnPhase 1/2Deciphera Pharmaceuticals, LLCNCT05080621Written as Ripretinib
Given beside what is tested · 1 — ripretinib is usual care or a partner of the new treatment
Codes
What other systems call ripretinib · ClinicalTrials.gg INT001343
- MeSH (NLM) C000707850ripretinibConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) 9XW757O13DRIPRETINIBConfirmed FDA, NLM, Wikidata
- RxNorm 2369389One source FDA
- Wikidata Q27076996ripretinibConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C124067RipretinibOne source FDA
- DrugBank DB14840One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C000707850 | ripretinib | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 9XW757O13D | RIPRETINIB | Confirmed FDA, NLM, Wikidata |
| RxNorm | 2369389 | — | One source FDA |
| Wikidata | Q27076996 | ripretinib | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C124067 | Ripretinib | One source FDA |
| DrugBank | DB14840 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.