Rifabutin: all 48 studies that test it

Page 1 of 1. Open to participants first (3), then studies with results posted, then the rest; newest registration first within each.

• The Effect of Rifabutin in Mycobacterium Abscessus With Inducible Clarithromycin ResistanceRecruitingNCT07514364Phase 4
• Rifabutin Versus Rifampicin for Treatment of Staphylococcal PJI Treated With DAIRRecruitingNCT04672525Phase 3
• Finding the Optimal Regimen for Mycobacterium Abscessus TreatmentRecruitingNCT04310930Phase 2/3
• The Effect of Moderate CYP3A Inducer Rifabutin on the Pharmacokinetics of Zanubrutinib in Healthy MalesCompletedNCT04470908Phase 1Results posted
• A Clinical Trial of the Safety, Pharmacokinetics and Hematologic Effects of Imatinib on Myelopoiesis in Adults When Given With and Without Isoniazid and RifabutinCompletedNCT03891901Phase 2Results posted
• Effect of Rifabutin on the Pharmacokinetics of Oral Cabotegravir in Healthy SubjectsCompletedNCT03149848Phase 1Results posted
• A Drug Interaction Study Investigating the Effect of Rifabutin on the Pharmacokinetics of MaravirocCompletedNCT01894776Phase 1Results posted
• Rifampin-Based Tuberculosis Treatment Versus Rifabutin-Based Tuberculosis Treatment in Persons With HIVTerminatedNCT01601626Phase 2Results posted
• Rifabutin Based Therapy for the Eradication of Staphylococcus Aureus Colonization in HIV Infected AdultsTerminatedNCT00869518Phase 2Results posted
• Drug Interaction StudyCompletedNCT00646776Phase 1Results posted
• A Study of Rifabutin and MK-4646 in Healthy Participants (MK-4646-004)CompletedNCT07199452Phase 1
• Rescue Therapy for Helicobacter Pylori InfectionCompletedNCT05874544Phase 4
• Short-course Regimens for the Treatment of Pulmonary TuberculosisActive, not recruitingNCT05766267Phase 2/3
• Impact of Rifabutin on the Pharmacokinetics of Elexacaftor/Tezacaftor/IvacaftorCompletedNCT04840862Phase 4
• Effectiveness of Rifabutin for Treatment of Helicobacter PyloriStatus unknownNCT04652284Phase 3
• Non-invasive Test-guided Tailored Therapy Versus Empiric Treatment for Helicobacter Pylori Infection.Status unknownNCT04107194Phase 3
• Genotypic Resistance-guided Versus Empirical Therapy for H. Pylori Eradication.Status unknownNCT04090021Phase 4
• Anti-chlamydophila Antibiotic Combination Therapy in the Treatment of Patients With Coronary Heart DiseaseTerminatedNCT03618108Phase 2
• Rifampicin vs Rifabutin in HIV/AIDS Patients Combined With TuberculosisStatus unknownNCT03478033Not applicable
• Effectiveness of Rifabutin in the Treatment of Mycobacterium Avium ComplexCompletedNCT03164291Phase 3
• Pharmacokinetics and Safety of Rifabutin 150 mg Once Daily Versus Rifabutin 300 mg Thrice WeeklyCompletedNCT02415985Phase 2
• Effects of Steady-state TPV/RTV on the Single-dose Pharmacokinetics of Rifabutin and the Effects of Single-dose Rifabutin on the Steady-state Pharmacokinetics of TPV in Healthy Adult VolunteersCompletedNCT02251171Phase 1
• Study to Determine the Effects of Nevirapine (VIRAMUNE®) on the Steady State Pharmacokinetics of Rifabutin (MYCOBUTIN®) in HIV+ PatientsCompletedNCT02184078Phase 4
• Drug-drug Interaction (DDI) RifabutinCompletedNCT02138084Phase 1
• EARNEST Rifabutin Pharmacokinetics (PK) SubstudyStatus unknownNCT01663168Phase 2
• A Study to Explore the Pharmacokinetics of Rilpivirine With Rifabutin in Healthy ParticipantsCompletedNCT01615614Phase 1
• TMC207 +/- Rifabutin/RifampinCompletedNCT01341184Phase 1
• Dosing, Safety and Pharmacokinetic Profile of Rifabutin in Children Receiving Concomitant Treatment With KaletraStatus unknownNCT01259219Phase 1
• Phase 1, Open Label, Two Arm, Fixed Sequence Study to Evaluate the Effect of Rifampin and Rifabutin on GSK1349572 Pharmacokinetics in Healthy Male and Female VolunteersCompletedNCT01231542Phase 1
• Drug Interaction Study Between Rifabutin And Lersivirine (UK-453,061)CompletedNCT00925535Phase 1
• A Bioavailability Study of Rifabutin and Lopinavir/Ritonavir in Healthy Adult SubjectsTerminatedNCT00743470Phase 1
• Use of Azithromycin and Rifabutin Administered 3 Times Weekly for the Treatment of M. Avium Complex (MAC) Lung DiseaseCompletedNCT00598962Phase 4
• Use of Clarithromycin and Rifabutin for the Treatment of M. Avium Complex (MAC) Lung DiseaseCompletedNCT00598897Phase 4
• TBTC Study 23C: Pharmacokinetics of Intermittent Rifabutin and Isoniazid With Daily EfavirenzCompletedNCT00023413Phase 2
• TBTC Study 23B:Intensive PK of the Nelfinavir Rifabutin Interaction in Patients With HIV-TBCompletedNCT00023400Phase 4
• TBTC Study 23: Treatment of HIV-Related Tuberculosis Using a Rifabutin-Based RegimenCompletedNCT00023361Not applicable
• TBTC Study 23A: Pharmacokinetics of Intermittent Isoniazid and Rifabutin in HIV-TBCompletedNCT00023348Phase 2/3
• Intensive Pharmacokinetics of the Nelfinavir-Rifabutin Interaction in Patients With HIV-Related Tuberculosis Treated With a Rifabutin-Based RegimenStatus unknownNCT00018083Not applicable
• A Study of Rifabutin, Used Alone or With Ethambutol in the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in Patients With AIDSCompletedNCT00002343Phase 4
• Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in AIDS Patients With CD4 Counts = or < 200: A Double-Blind, Placebo-Controlled TrialCompletedNCT00002267Not applicable
• A Three-Arm Comparative Trial for the Treatment of MAC Bacteremia in AIDS: A Clarithromycin/Ethambutol Regimen Containing Rifabutin (450 Mg) or Rifabutin (300 Mg) or PlaceboCompletedNCT00002101Phase 3
• Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in HIV Positive Patients With CD4 Counts = or < 200: Treatment IND StudyCompletedNCT00002080Not applicable
• Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in AIDS Patients With CD4 Counts = or < 200: A Double-Blind, Placebo-Controlled TrialCompletedNCT00002032Not applicable
• A Double-Blind Randomized Clinical Trial of a Rifabutin Regimen in the Treatment of Mycobacterium-Avium Complex (MAC) Bacteremia in Patients With AIDSCompletedNCT00001995Not applicable
• The Safety and Effectiveness of Clarithromycin and Rifabutin Used Alone or in Combination to Prevent Mycobacterium Avium Complex (MAC) or Disseminated MAC Disease in HIV-Infected PatientsCompletedNCT00001030Phase 3
• The Safety and Effectiveness of Rifabutin, Combined With Clarithromycin or Azithromycin, in HIV-Infected PatientsCompletedNCT00001023Not applicable
• Study of How Indinavir (an Anti-HIV Drug) and Rifabutin (a Drug Used to Treat MAC, an HIV-Associated Disease) Interact in HIV-Positive and HIV-Negative AdultsCompletedNCT00000877Phase 1
• Effect of Fluconazole, Clarithromycin, and Rifabutin on the Pharmacokinetics of Sulfamethoxazole-Trimethoprim and Dapsone and Their Hydroxylamine MetabolitesCompletedNCT00000826Phase 1

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