Reverse Transcriptase Inhibitors: all 1,328 studies that test it

Page 12 of 14. Open to participants first (42), then studies with results posted, then the rest; newest registration first within each.

• An Open Parallel Study to Determine the Optimum Dosing Schedule for AS-101 in AIDS/ARC PatientsCompletedNCT00002266Not applicable
• An Open-Label, Multicenter Study to Evaluate the Safety and Tolerability of Dideoxycytidine (ddC) in Patients With AIDS or Advanced ARC Who Previously Demonstrated Intolerance to Zidovudine (AZT) in Protocol N3300 or N3492CompletedNCT00002265Phase 2
• Dideoxycytidine ( Ro 24-2027 ). A Treatment Protocol for the Use of Dideoxycytidine ( ddC ) in Patients With AIDS or Advanced ARC Who Cannot Be Maintained on Zidovudine ( AZT ) Therapy.CompletedNCT00002256Not applicable
• An Open-Label Phase I/II Study of Recombinant Granulocyte Colony Stimulating Factor (r-metHuG-CSF) and Recombinant Erythropoietin (rHuEPO) Given Subcutaneously Along With Zidovudine (AZT) to Patients With the Acquired Immune Deficiency Syndrome (AIDS) or Severe AIDS-Related Complex (ARC)CompletedNCT00002255Phase 1
• A Study to Evaluate the Use of Stavudine (d4T) to Treat AIDS Dementia ComplexCompletedNCT00002246Phase 3
• A Study to Compare Three Doses of T-20 When Given in Combination With Abacavir, Amprenavir, Ritonavir, and Efavirenz to HIV-Infected AdultsCompletedNCT00002239Phase 2
• A Study to Find the Best Dosing Schedule for Delavirdine, Zidovudine, and Indinavir in HIV-Positive PatientsCompletedNCT00002236Not applicable
• A Study on the Safety and Effectiveness of Twice-Daily Nelfinavir Plus Twice-Daily Indinavir Plus Efavirenz in HIV-Positive Patients Who Have Never Taken Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) or Protease InhibitorsCompletedNCT00002235Phase 2
• Safety and Effectiveness of Giving an Anti-HIV Drug Combination of Adefovir Dipivoxil Plus Didanosine Plus Efavirenz Plus Lamivudine Once Daily to HIV-Infected PatientsCompletedNCT00002234Phase 2
• A Study of a Combination of Four Drugs in Patients With Recent HIV InfectionCompletedNCT00002233Phase 2
• A Randomized, Placebo-Controlled Study of the Safety and Efficacy of Efavirenz, Didanosine, and Stavudine in Combination With or Without Hydroxyurea in Antiretroviral Naive or Experienced HIV-Infected PatientsCompletedNCT00002230Phase 3
• A Study of Efavirenz in HIV-Infected Patients Who Have Never Taken Anti-HIV DrugsCompletedNCT00002227Phase 2
• A Study of Efavirenz in Combination With Stavudine and DidanosineCompletedNCT00002225Phase 2
• Comparison of Two Anti-HIV Regimens That Include One of Two Forms of Didanosine (ddI)CompletedNCT00002224Phase 3
• Indinavir Plus Efavirenz Plus Adefovir Dipivoxil in HIV-Infected Patients Who Have Not Had Success With NelfinavirCompletedNCT00002220Phase 3
• Safety and Effectiveness of Adding Adefovir Dipivoxil and Nelfinavir to the Anti-HIV Therapy of HIV-Infected ChildrenStatus unknownNCT00002219Phase 2
• A Study of Combivir Plus Abacavir Plus 141W94 in Patients Who Previously Have Used Anti-HIV DrugsCompletedNCT00002217Not applicable
• Phase I Trial of S-1153 in Patients With HIV InfectionCompletedNCT00002214Phase 1
• Safety and Effectiveness of Giving Combinations of Three or Four Anti-HIV Drugs to HIV-Infected PatientsCompletedNCT00002211Not applicable
• A Study of Delavirdine Mesylate in Combination With Other Anti-HIV Drugs in HIV-Infected Children and BabiesCompletedNCT00002210Phase 2
• A Multicenter, Open-Label, Randomized, 24-Week Study to Compare the Safety and Activity of Indinavir Sulfate, 800 Mg q 8 h Versus 1,200 Mg q 12 h in Combination With Zidovudine and 3TCCompletedNCT00002208Phase 3
• A Comparison of Two Dose Levels of Didanosine Used in Combination With Stavudine in HIV-Infected PatientsCompletedNCT00002207Not applicable
• A Study of Adefovir Dipivoxil in HIV-Infected Patients Who Have Not Been Treated With Anti-HIV DrugsCompletedNCT00002206Phase 1
• An Open-Label Study to Evaluate the Efficacy and Safety of Amprenavir (141W94) and Abacavir Combination Therapy in Protease Inhibitor Experienced Subjects With HIV-1 Infection Who Are Failing Their Current Antiretroviral Treatment RegimenCompletedNCT00002205Not applicable
• A Study of 1592U89 in HIV-Infected AdultsCompletedNCT00002200Not applicable
• A Study of 1592U89 and Ethanol When Given Together to HIV-Infected PatientsCompletedNCT00002198Phase 1
• A Study of 1592U89 in HIV-Infected ChildrenCompletedNCT00002197Not applicable
• An Open-Label Study in HIV+ Patients to Determine the Effects of Nevirapine (Viramune) on the Pharmacokinetics of Clarithromycin and Activity of Cytochrome 3A4.CompletedNCT00002194Phase 1
• A Phase II Open-Label Exploratory Study of Saquinavir + Zidovudine + Lamivudine in HIV Infected PatientsCompletedNCT00002190Phase 2
• A Phase II, Stratified, Randomized, Double-Blind, Multi-Center Study of the Safety and Efficacy of Adefovir Dipivoxil (ADF) at Two Dose Levels in Triple Combination Therapies With Protease Inhibitors (PI) and Nucleoside Reverse Transcriptase Inhibitors (RTI) for the Treatment of HIV-Infected PatientCompletedNCT00002184Phase 2
• A Study of PMPA in HIV-Infected PatientsCompletedNCT00002180Phase 1
• The Effectiveness of Indinavir Plus Zidovudine Plus Lamivudine in HIV-Infected Patients With No Symptoms of InfectionCompletedNCT00002179Phase 4
• A Pilot Open Label Trial of HIV Therapy With d4T (Stavudine), ddI (Didanosine), Nelfinavir and Hydroxyurea in Subjects With Recent HIV InfectionCompletedNCT00002177Not applicable
• A Pilot Open Label Trial of HIV Therapy With d4T (Stavudine), ddI (Didanosine), Nelfinavir and Hydroxyurea in Subjects With Early Asymptomatic HIV InfectionCompletedNCT00002176Not applicable
• An Open-Label, Non-Randomized Trial to Evaluate the Tolerability and Safety of Viramune (Nevirapine) in Adult and Pediatric Patients With Progressive HIV DiseaseCompletedNCT00002166Phase 3
• A Phase III, Randomized, Double-Blind, Multicentre Study to Evaluate the Safety and Efficacy of 1592U89 in Patients With AIDS Dementia ComplexCompletedNCT00002163Phase 3
• A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Adefovir Dipivoxil When Added to Standard Antiretroviral Therapy for the Treatment of HIV-Infected Patients With CD4 Cell Counts >= 200/mm3CompletedNCT00002161Not applicable
• A Six-Month Safety and Antiviral Study in HIV-1 Seropositive, AZT-Experienced Patients With CD4 Counts Less Than or Equal to 50 Cells/mm3 to Evaluate MK-639 Alone Versus Zidovudine (AZT) and 3TC Versus the Combination of MK-639 With AZT/3TCCompletedNCT00002155Not applicable
• Phase III Multicenter, Open-Label, Randomized Trial of Induction Versus Induction Plus Maintenance Foscarnet ( Foscavir ) Therapy for Gastrointestinal CMV DiseaseCompletedNCT00002145Phase 3
• The Pilot Study of Foscarnet Cream in the Treatment of Mucocutaneous Herpes Simplex Virus Infections in Immunocompromised Patients Unresponsive to Acyclovir TreatmentCompletedNCT00002144Phase 1
• A Phase I Trial to Evaluate the Safety and Pharmacokinetics of 1592U89CompletedNCT00002141Phase 1
• Phase I Study of the Safety, Tolerance, and Pharmacokinetics of 9-[2-(Bispivaloyloxymethyl)Phosphonylmethoxyethyl]Adenine (Bis-POM PMEA; Adefovir Dipivoxil) in HIV-Infected PatientsCompletedNCT00002128Phase 1
• A Multicenter Study of Oral Versus Intravenous Hydration in AIDS Patients With CMV Retinitis Treated With Foscavir (Foscarnet Sodium)CompletedNCT00002125Phase 4
• A Double-Blind, Randomized, Dose Response Study of Three Doses of Delavirdine Mesylate (U-90152S) in Combination With Zidovudine (ZDV) Versus ZDV Alone in HIV-1 Infected Individuals With CD4 Counts of 200-500mm3CompletedNCT00002124Phase 3
• A Double-Blind, Randomized, Comparative Study of Delavirdine Mesylate (U-90152S) in Combination With Didanosine (ddI) Versus ddI Alone in HIV-1 Infected Individuals With CD4 Counts of <= 300/mm3CompletedNCT00002123Phase 3
• An Open-Label Safety Program for the Use of Zalcitabine (Dideoxycytidine; ddC) in Pediatric Patients With Symptomatic HIV Infection Who Have Failed or Are Intolerant to AZT Monotherapy, or Who Have Completed Other ddC Protocols, or Are Ineligible for Other Ongoing Clinical StudiesCompletedNCT00002118Not applicable
• A Randomized, Open-Label Study of Alternative Treatment Combinations of Dideoxycytidine (HIVID; ddC) and Zidovudine (AZT) in Patients With HIV InfectionCompletedNCT00002117Phase 3
• A Phase I/II Study of the Safety, Tolerance, and Pharmacokinetics of 9-(2-Phosphonylmethoxyethyl)Adenine ( PMEA; Adefovir ) in Patients With Advanced HIV Disease.CompletedNCT00002115Phase 1
• A Phase II/III Study of Cysteamine (Mercaptoethylamine) and Zidovudine for the Treatment of HIV DiseaseCompletedNCT00002110Phase 2
• 3TC (Lamivudine; GR109714X) Open-Label ProgramCompletedNCT00002108Not applicable
• Phase II/III Study of the Tolerance and Efficacy of Combined Use of Didanosine (2',3'-Dideoxyinosine; ddI) and Lentinan in HIV-Positive PatientsStatus unknownNCT00002099Phase 2
• Phase I/II Study of the Tolerance and Efficacy of Combined Use of Didanosine (2',3'-Dideoxyinosine; ddI) and Lentinan in HIV-Positive PatientsCompletedNCT00002098Phase 1
• A Phase I Pharmacokinetic Study in HIV-Positive Subjects of Oral Ganciclovir and Concomitant Antiretroviral Zidovudine and DidanosineCompletedNCT00002096Phase 1
• Prospective Open-Label Study of the Emergence of Drug Resistance in Patients Infected With HIV-1 Who Are Taking Oral U-87201ECompletedNCT00002094Not applicable
• Open-Label Program of Dideoxycytidine ( ddC ) to Be Used in Combination With Zidovudine ( AZT ) for Treatment of Advanced HIV DiseaseCompletedNCT00002081Not applicable
• Treatment of AIDS and AIDS Related Complex. Part-1- Treatment of Patients With ARC (AZT Vs. Placebo)CompletedNCT00002063Not applicable
• The Efficacy and Safety of Retrovir in Patients Infected With HIV Who Are Asymptomatic (CDC Group II) or Have Persistent Generalized Lymphadenopathy (CDC Group III)CompletedNCT00002048Not applicable
• Retrovir Capsules in the Treatment of HIV-Infected Patients in Renal FailureCompletedNCT00002047Not applicable
• A Dose-Frequency Trial of Oral Retrovir in Patients With AIDS or Severe ARCCompletedNCT00002046Not applicable
• A Prospective Double-Blind Study of Retrovir in Early HIV InfectionCompletedNCT00002045Not applicable
• A Pilot Study To Evaluate the Effect of Retrovir (Zidovudine: AZT) in the Treatment of Human Immunodeficiency Virus (HIV) Associated Dementia and Neuromuscular DiseasesCompletedNCT00002044Not applicable
• An Open Study of Foscarnet Treatment First Episode CMV-Retinitis in AIDS PatientsCompletedNCT00002039Not applicable
• Double-Blind Comparison of the Efficacy of Continued Zidovudine Versus 2',3'-Dideoxyinosine (ddI) (BMY-40900) for the Treatment of Patients With AIDS or AIDS-Related Complex and Increasing Symptomatology Despite Treatment With ZidovudineCompletedNCT00002035Not applicable
• A Third-Party Blinded, Placebo Controlled Comparative Study of AS-101 Administered Intravenously in HIV Positive Patients With Advanced DiseaseCompletedNCT00002033Not applicable
• A Treatment IND (Investigational New Drug) Protocol for the Use of Videx (2',3'-Dideoxyinosine, ddI) in Patients With Acquired Immunodeficiency Syndrome (AIDS) or AIDS- Related Complex (ARC) Who Are Intolerant to Zidovudine (Retrovir)CompletedNCT00002028Not applicable
• An Oral Dose-Ranging Finding Study in Patients With HIV Disease, CDC Classification Groups IIB, III, and IV-C2CompletedNCT00002023Not applicable
• An Open Study of Foscarnet Treatment of Acyclovir-Resistant Herpes Simplex Virus in Patients With the Acquired Immunodeficiency Syndrome and Other ImmunodeficienciesCompletedNCT00002021Not applicable
• Trial of an Alternative Dosing Regimen of Oral Retrovir in Patients With AIDS or Advanced ARCCompletedNCT00002020Not applicable
• A Phase I Study to Evaluate the Pharmacokinetics, Safety and Antiviral Effects of Concurrent Administration of Zidovudine (AZT) and 2'3'-Dideoxyinosine (ddI) in Patients With Human Immunodeficiency Virus (HIV)CompletedNCT00002014Phase 1
• A Safety, Pilot Pharmacokinetics and Neurocognitive Study of AS-101 in Combination With Zidovudine in AIDS/ARC PatientsCompletedNCT00002013Not applicable
• The Antiviral Efficacy of Concurrent Zidovudine and 2',3'-Dideoxyinosine or 2',3'-Dideoxycytidine in Patients With Human Immunodeficiency Virus DiseaseCompletedNCT00002001Not applicable
• Safety and Efficacy of Polyethylene Glycolated IL-2 (PEG IL-2) Plus Zidovudine or Dideoxyinosine in HIV Positive, Asymptomatic and Symptomatic IndividualsCompletedNCT00001997Not applicable
• Initial Phase II Efficacy and Safety Study of SC-48334 Administered in Combination With Low-Dose Zidovudine (AZT) to Symptomatic HIV-1 Infected Patients With = or > 200 to = or < 500 CD4+ Cells/mm3CompletedNCT00001993Phase 2
• A Randomized Phase II Efficacy, Activity and Safety Study of GLQ223 Alone and in Combination With Zidovudine in Symptomatic HIV-Infected Patients Without Prior Treatment With GLQ223 or TrichosanthinCompletedNCT00001989Phase 2
• Once-Daily Drug Regimen for HIV-Infected PatientsCompletedNCT00001968Phase 1
• Continued Antiretroviral Therapy With Abacavir, Amprenavir and EfavirenzCompletedNCT00001758Phase 2
• A Pilot Study of the Immunologic Reconstitution in HIV-1 Infected Children Receiving Highly Active Antiretroviral Therapy With Combination Ritonavir, Nevirapine and StavudineCompletedNCT00001688Phase 2
• Lamivudine for Chronic Hepatitis BCompletedNCT00001457Phase 2
• Interleukin-2 Therapy for HIV Infection - Supplemental ProceduresCompletedNCT00001354Phase 2
• A Phase I/II Study of the Combination of Azidothymidine and Interleukin-2 (IL-2) in the Treatment of HIV-Infected PatientsCompletedNCT00001282Phase 2
• A Randomized Pilot Study for the Treatment of AIDS or AIDS Related Complex With an Alternating or Simultaneous Combination Regimen of AZT and 2',3'-DideoxyinosineCompletedNCT00001267Phase 3
• A Study of Nevirapine to Prevent HIV Transmission From Mothers to Their InfantsCompletedNCT00001135Phase 3
• Effectiveness of the Early Addition of Abacavir to an Anti-HIV Drug CombinationCompletedNCT00001132Phase 2
• The Safety and Effectiveness of Interferon Alfa-2B Plus Didanosine in Patients With Kaposi's SarcomaCompletedNCT00001114Phase 2
• The Safety and Effectiveness of Injections of Human Recombinant Interferon-gamma in Patients With AIDS Who Have Taken ZidovudineCompletedNCT00001112Phase 1
• A Study of Nevirapine Used Alone or in Combination With AZT in HIV-1-Infected ChildrenCompletedNCT00001111Not applicable
• A Study of Zidovudine in HIV-Infected Pregnant Women and Their ChildrenCompletedNCT00001106Phase 1
• A Study of Zidovudine in HIV-Infected Patients Who Have HemophiliaCompletedNCT00001104Phase 3
• A Comparison of Nelfinavir Plus Saquinavir Plus Delavirdine or 3TC/ZDV Versus Nelfinavir Plus 3TC/ZDV in HIV-Infected PatientsWithdrawnNCT00001094Phase 2
• The Effectiveness of Nelfinavir and Efavirenz, Used Alone or Together, Combined With Other Anti-HIV Drugs in Patients Who Have Taken Anti-HIV DrugsCompletedNCT00001087Phase 2
• A Study of Abacavir Plus Indinavir Sulfate Plus Efavirenz in HIV-Infected PatientsCompletedNCT00001086Phase 2
• A Study of 141W94 Used Alone or in Combination With Zidovudine Plus 3TC in HIV-Infected PatientsCompletedNCT00001085Phase 2
• A Study of Three Treatment Combinations Using Zidovudine Plus Lamivudine Plus Indinavir in HIV-Infected PatientsCompletedNCT00001084Phase 2
• Comparison of New Anti-HIV Drug Combinations in HIV-Infected Children Who Have Taken Anti-HIV DrugsCompletedNCT00001083Phase 2
• The Safety and Effectiveness of Adefovir Dipivoxil in the Treatment of HIV-Infected PatientsCompletedNCT00001082Phase 3
• Effect of Vaccination on Turnover of Lamivudine (3TC) Sensitive and Resistant Virus Populations in HIV-1-Infected IndividualsWithdrawnNCT00001080Not applicable
• The Effectiveness of Ritonavir Plus Zidovudine Plus Lamivudine in HIV-Infected PatientsCompletedNCT00001075Not applicable
• A Study of Disease Progression and Anti-HIV TreatmentsCompletedNCT00001068Phase 2
• The Effectiveness of Three Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Never Used Anti-HIV DrugsCompletedNCT00001067Phase 2
• A Comparison of Zidovudine Plus Lamivudine Versus ddI Used Alone or in Combination With Zidovudine in HIV-1 Infected ChildrenCompletedNCT00001066Phase 2

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