Pyrimethamine: all 34 studies that test it
Page 1 of 1. Open to participants first (4), then studies with results posted, then the rest; newest registration first within each.
- Combining Latency Reversing Agents to Address the HIV ReservoirNot yet recruitingNCT07384624Phase 1/2
- Seasonal Malaria Chemoprevention Rapid Assessment Study MozambiqueNot yet recruitingNCT06337253Phase 4
- Optimizing Reversal of HIV Latency With Combination TherapyNot yet recruitingNCT06240520Phase 1/2
- Pyrimethamine, Sulfadiazine, and Leucovorin in Treating Patients With Congenital ToxoplasmosisRecruitingNCT00004317Phase 4
- Sanaria PfSPZ Challenge With Pyrimethamine or Chloroquine Chemoprophylaxis Vaccination (PfSPZ-CVac Approach): A Randomized Double Blind Placebo Controlled Phase I/II Trial to Determine Safety and Protective Efficacy Against Natural Plasmodium Falcipa...CompletedNCT03952650Phase 1/2Results posted
- Phase I Study of Pyrimethamine in Healthy Japanese and Caucasian SubjectsCompletedNCT03258762Phase 1Results posted
- Dose Escalation PfSPZ-CVacCompletedNCT03083847Phase 1Results posted
- SOD1 Inhibition by Pyrimethamine in Familial Amyotrophic Lateral Sclerosis (ALS)CompletedNCT01083667Phase 1/2Results posted
- Pyrimethamine for the Treatment of Relapsed Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaCompletedNCT01066663Phase 1/2Results posted
- Pyrimethamine as an Inhibitor of NRF2 in HPV-unrelated Locally Advanced Head and Neck Squamous Cell CarcinomaCompletedNCT05678348Early Phase 1
- An Investigational Study to Determine the Drug Level Profile of BMS-986165 in Healthy Male Volunteers Following Transporter Inhibition.CompletedNCT04086719Phase 1
- LRAs United as a Novel Anti-HIV Strategy.CompletedNCT03525730Phase 1/2
- Pyrimethamine for Intermediate/High-risk Myelodysplastic Syndromes (MDS)WithdrawnNCT03057990Phase 1
- Sanaria PfSPZ Challenge With Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Trial to Determine Safety and Protective Efficacy of Sanaria PfSPZ Challenge With Concurrent Pyrimethamine Treatment That Inhibits Development of Asexual B...CompletedNCT02511054Phase 1
- Prevention of Congenital Toxoplasmosis With Pyrimethamine + Sulfadiazine Versus Spiramycine During PregnancyCompletedNCT01189448Phase 3
- Pyrimethamine as a Treatment for Late-Onset GM2-gangliosidosis (Tay-Sachs and Sandhoff Disease)CompletedNCT01102686Phase 1/2
- A Randomised Trial of Artesunate-sulfamethoxypyrazine/Pyrimethamine Versus Praziquantel for the Treatment of S. MansoniCompletedNCT01054651Phase 3
- A Phase I Study of Pyrimethamine in Patients With GM2 GangliosidosisWithdrawnNCT00679744Phase 1
- Antimalarial Treatments for Clearing Low Density P. Falciparum and Its Impact on Malaria TransmissionCompletedNCT00646126Phase 3
- Comparison of Two Strategies for the Delivery of IPTcCompletedNCT00376155Phase 4
- IPT and Efficacy of Sulphadoxine/Pyrimethamine and Chlorproguanil/Dapsone in 6-59 Month Old Children With Malaria.TerminatedNCT00361114Phase 3
- SP Resistance and Falciparum Malaria TransmissionWithdrawnNCT00299247Phase 3
- Intermittent Treatment With Sulfadoxine-pyrimethamine for Malaria Control in InfantsCompletedNCT00206739Phase 4
- Efficacy of Combination Therapy for Prevention of Effects of Malaria During PregnancyCompletedNCT00164255Phase 4
- Anti-Malarial Drug Resistance in CameroonCompletedNCT00146718Phase 2/3
- A Trial of Intermittent Treatment in the Prevention of Malaria in Senegalese ChildrenCompletedNCT00132561Phase 2/3
- CQSP in Malawi: Chloroquine and Sulfadoxine-pyrimethamine Efficacy for the Treatment of Malaria in MalawiCompletedNCT00125489Phase 4
- Longitudinal Antimalarial Combinations in UgandaCompletedNCT00123552Phase 3
- Pyrimethamine to Treat Autoimmune Lymphoproliferative SyndromeCompletedNCT00065390Phase 1
- A Study of Pyrimethamine in the Treatment of Infection by a Certain Parasite in HIV-Positive PatientsCompletedNCT00000973Phase 1
- A Study of Azithromycin Plus Pyrimethamine in the Treatment of a Brain Infection in Patients With AIDSCompletedNCT00000966Phase 1
- Phase II Randomized Open-Label Trial of Atovaquone Plus Pyrimethamine and Atovaquone Plus Sulfadiazine for the Treatment of Acute Toxoplasmic EncephalitisCompletedNCT00000794Phase 2
- A Pilot Study of Oral Clindamycin and Pyrimethamine for the Treatment of Toxoplasmic Encephalitis in Patients With AIDSCompletedNCT00000674Not applicable
- A Randomized Prospective Study of Pyrimethamine Therapy for Prevention of Toxoplasmic Encephalitis in HIV-Infected Individuals With Serologic Evidence of Latent Toxoplasma Gondii InfectionCompletedNCT00000666Not applicable