Protein Kinase Inhibitors: all 15,766 studies that test it
Page 7 of 158. Open to participants first (2,605), then studies with results posted, then the rest; newest registration first within each.
- A Prospective, Single-arm, Open-label Clinical Trial to Evaluate the Efficacy and Safety of Ivarmacitinib in the Treatment of Palmoplantar PustulosisRecruitingNCT07270003Not applicable
- Golcadomide, Poseltinib, and Rituximab for Relapsed/Refractory Diffuse Large B-cell LymphomaNot yet recruitingNCT07269639Phase 1/2
- Phase II Study Assessing the Safety and Efficacy of Dasatinib in Combination With Ropeginterferon in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic PhaseRecruitingNCT07269470Phase 2
- Biologics in Folliculitis Decalvans : an Adaptative Trial ResearchNot yet recruitingNCT07268534Phase 2
- Efficacy and Safety of Ivarmacitinib in the Treatment of Patients With Polymyalgia RheumaticaNot yet recruitingNCT07266168Not applicable
- Phase 2A/B Efficacy and Safety of Dabogratinib in Participants With Low Grade Upper Tract Urothelial CarcinomaRecruitingNCT07265947Phase 2
- Sorafenib Combined With Venetoclax as Pre-emptive Therapy Strategy for MRD+ AML: a Prospective, Single-arm, Multicenter Clinical StudyNot yet recruitingNCT07264010Phase 2/3
- Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic DermatitisRecruitingNCT07262983Phase 1
- Trifluridine/Tipiracil Plus Fruquintinib vs. Trifluridine/Tipiracil Plus Bevacizumab in Refractory Metastatic Colorectal Cancer: A Randomized, Controlled, Open-Label, Non-Inferiority TrialNot yet recruitingNCT07261709Phase 2
- Comparison Between Oral Methotrexate and Tofacitinib in Chronic Plaque PsoriasisRecruitingNCT07261306Early Phase 1
- Obinutuzumab, Zanubrutinib, and Lenalidomide in First-line Treatment of Mantle Cell LymphomaRecruitingNCT07261163Phase 2
- Upadacitinib Combined With Corticosteroids vs Corticosteroid Monotherapy Induction for Inpatients and Outpatients With Acute Severe Ulcerative ColitisRecruitingNCT07258771Phase 4
- Pomalidomide Plus Orelabrutinib and Zuberitamab in Untreated Mantle Cell LymphomaRecruitingNCT07257510Not applicable
- A Clinical Trial of Envafolimab Combined With Lenvatinib for Kidney Cancer With Liver SpreadNot yet recruitingNCT07256223Phase 2
- Pirtobrutinib, Lisaftoclax, and Rituximab in the Treatment of R/R DLBCLRecruitingNCT07255963Phase 2
- Bone Marrow Protection, Safety, Efficacy of Trilaciclib and Eribulin in Locally Advanced or Metastatic TNBC(Triple-negative Breast Cancer)Not yet recruitingNCT07255612Phase 2
- Ruxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell DiseaseRecruitingNCT07252050Phase 1/2
- A Trial of SHR0302 Tablets and SHR0302 Base Gel in Patients With Non-segmental VitiligoRecruitingNCT07251595Phase 2
- A Long-Term Study of Zasocitinib in Children and Teenagers With Plaque PsoriasisRecruitingNCT07250802Phase 3
- Asciminib Maintenance Therapy Following alloHCT or CAR T to Prevent Relapse in Adults With Ph+ALLRecruitingNCT07250087Phase 1
- Dose-Expansion Study of Low Dose Post-Transplant Cyclophosphamide/Tacrolimus/Ruxolitinib for Graft-versus-Host Disease (GVHD) Prophylaxis in Myeloablative Allogeneic Peripheral Blood Stem Cell TransplantationRecruitingNCT07249346Phase 2
- A Phase II Single-Arm Study of High-Bioavailability Curcumin as Neoadjuvant Chemoradiotherapy in Mid-to-Low Rectal Cancer: Integrated Clinical and Translational Analysis of Tumor TissueNot yet recruitingNCT07248020Phase 2
- A Study of Zasocitinib in Adults With Hidradenitis SuppurativaRecruitingNCT07244263Phase 2
- Treatment of Atopic Dermatitis and Alopecia Areata With Abrocitinib in Individuals With Down SyndromeRecruitingNCT07242638Phase 2
- Optimization of Post-transplantation Benadamustine and Cyclophosphamide in Patients With High-risk Myeloid Malignancies and a Partially Mismatched DonorRecruitingNCT07238712Phase 2
- A Study to Evaluate Efficacy and Safety of LNK01001 in Adults With Ankylosing SpondylitisRecruitingNCT07237568Phase 3
- Mirdametinib in Patients With Advanced NF1-mutant MelanomaRecruitingNCT07237100Phase 2
- Combination of Carilizumab, Apatinib, and Radiotherapy for Advanced Mucosal MelanomaNot yet recruitingNCT07236528Phase 2
- Ensartinib After Chemoradiotherapy in Stage III ALK-Mutated NSCLCNot yet recruitingNCT07235306Phase 2
- A Study to Evaluate Effectiveness and Safety of a TYK2 Inhibitor in Subjects With Moderate to Severe Plaque PsoriasisRecruitingNCT07234591Not applicable
- A Phase 3 Multinational Study of Golidocitinib Versus Investigator's Choice in r/r PTCL (JACKPOT19)RecruitingNCT07234162Phase 3
- A Study of Pirtobrutinib, Venetoclax, and Rituximab in People With Waldenström's Macroglobulinemia (WM)/Lymphoplasmacytic Lymphoma (LPL)RecruitingNCT07231952Phase 2
- A Phase II Clinical Study of Aipalolitovorelizumab (QL1706) Combined With Fruquintinib in the Treatment of Immunodominant pMMR/MSS Metastatic Colorectal Cancer That Has Failed Second-line or Above TreatmentNot yet recruitingNCT07229872Phase 2
- Zipalertinib With Carboplatin and Pemetrexed for the Treatment of Resectable, Stage II-IIIB, Non-Small Cell Lung CancerNot yet recruitingNCT07229339Phase 2
- Ruxolitinib Before, During and After Hematopoietic Cell Transplant in Older Patients With Myelofibrosis and Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap SyndromesRecruitingNCT07228624Phase 2
- A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)RecruitingNCT07227402Phase 3
- Pacritinib in Participants With Metastatic Castrate-Resistant Prostate Cancer That Progressed on or After Prior Treatment With Androgen Receptor Signaling InhibitorsRecruitingNCT07226713Phase 2
- Maintenance Zanzalintinib and Durvalumab in Participants With Advanced Hepatocellular CancerNot yet recruitingNCT07226063Phase 2
- A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple SclerosisRecruitingNCT07225504Phase 3
- Dose-Adjusted EPOCH With or Without Rituximab Plus Ponatinib for the Treatment of Newly-Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia/LymphomaRecruitingNCT07224100Phase 2
- A Study of Remibrutinib Using MR Imaging in Relapsing or Progressive MSNot yet recruitingNCT07222956Phase 2
- A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)RecruitingNCT07222332Phase 3
- A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and AdultsRecruitingNCT07222137Phase 3
- Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID TrialRecruitingNCT07220187Phase 3
- A Study to Learn About Ritlecitinib for the Potential Treatment of Chronic Spontaneous Urticaria in Adults.RecruitingNCT07219615Phase 2
- Retifanlimab and Ruxolitinib In Solid MalignanciesRecruitingNCT07219576Phase 1/2
- A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib TherapyRecruitingNCT07218926Phase 3
- Zanzalintinib in Men With Aggressive Variant Prostate CancerRecruitingNCT07218666Phase 2
- Double-Blind Trial of Everolimus for Improving Social Abilities in PTEN Germline MutationsNot yet recruitingNCT07218575Phase 2/3
- A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary TractRecruitingNCT07218380Phase 3
- A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaRecruitingNCT07218341Phase 4
- Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 OverexpressionRecruitingNCT07214779Phase 3
- Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis SuppurativaRecruitingNCT07213973Phase 2
- STREAM-2: Second-line Treatment With REgorafenib in Advanced RAS-Mutant Colorectal CancerRecruitingNCT07213570Phase 2
- A Study of Elacestrant Alone or in Combination With Abemaciclib in People With Endometrial CancerRecruitingNCT07209449Phase 2
- Baricitinib Curative Repression of HIV-1Not yet recruitingNCT07209267Phase 2
- Combination Therapy With Tazemetostat in Relapsed and Refractory Peripheral T-cell LymphomaNot yet recruitingNCT07209163Phase 1/2
- Orelabrutinib Combined With Zebetuzumab and Lenalidomide for the Treatment of Newly Diagnosed MZLRecruitingNCT07208981Phase 2
- PirtobrUtinib as Frontline Therapy for Elderly Unfit/Frail Patient With MAntle Cell LymphomaNot yet recruitingNCT07207785Phase 2
- A Randomised, Open-label, Multicentre Phase III Clinical Study to Evaluate the Efficacy and Safety of JS105 Combined With Dalpiciclib and Fulvestrant Compared With Dalpiciclib and Fulvestrant in Patients With PIK3CA-mutated, HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer.RecruitingNCT07207070Phase 3
- Study of Tovorafenib in High-Grade Glioma and Diffuse Intrinsic Pontine Glioma (DIPG)Not yet recruitingNCT07206849Phase 2
- A Study to Evaluate Safety and Efficacy of WSD0922-FU Combo With Osimertinib for NSCLCRecruitingNCT07206498Phase 1/2
- Chemotherapy Combined With Targeted Therapy as First-line Treatment for Mantle Cell Lymphoma Based on MRD and PET-CT AssessmentNot yet recruitingNCT07206264Phase 2
- A Multicenter, Single-arm, Prospective Phase II Clinical Study of Epalrotokewali Combined With Eribulin, Anlotinib, and Radiotherapy for the Treatment of Patients With Advanced Soft Tissue Sarcoma.Not yet recruitingNCT07205185Phase 2
- Tebentafusp and Roginolisib in Uveal Melanoma to Prolong T-cell HomeostasisRecruitingNCT07203391Phase 1
- The Role of Janus Kinase (JAK) and Voltage-gated Sodium Channels (Nav) on Pain and ItchNot yet recruitingNCT07203274Not applicable
- Orelabrutinib and Rituximab With Optional Autologous Hematopoietic Stem Cell Transplantation in MCL TreatmentRecruitingNCT07199296Phase 2
- An Exploratory Study of Golidocitinib in Adult Patients With ITPNot yet recruitingNCT07196163Phase 1/2
- Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD MutationsRecruitingNCT07195695Phase 3
- Efficacy and Safety of Camizestrant Plus Ribociclib in Patients With Breast CancerRecruitingNCT07195227Phase 2
- Nemtabrutinib and Lisocabtagene Maraleucel for the Treatment of Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaRecruitingNCT07194980Phase 2
- Metastatic Ewing's Trial Testing Schedule Enhancement to Improve OutcomesRecruitingNCT07194044Phase 1
- A Phase 2 Trial of Zanzalintinib in Advanced/Metastatic Bone Sarcomas (ZAMBONE)RecruitingNCT07193550Phase 2
- Tucatinib and Trastuzumab in HER3-mutant and HER2-not Amplified Metastatic Breast CancerRecruitingNCT07193394Phase 2
- Anlotinib and Benmelstobart in DTCNot yet recruitingNCT07193186Phase 2
- Sacituzumab Tirumotecan in Combination With Furmonertinib as Second-line Treatment for EGFR-mutant Advanced or Metastatic NSCLC After Failure of First-line Third-generation EGFR-TKI TherapyNot yet recruitingNCT07193160Phase 2
- Adebrelimab + Apatinib in Advanced HCC Post-Systemic TherapyNot yet recruitingNCT07192848Phase 2
- Neoadjuvant Camrelizumab With Palbociclib for Resectable Esophageal Squamous Cell CarcinomaNot yet recruitingNCT07191977Phase 2
- Imlunestrant and Abemaciclib for the Treatment of Estrogen Receptor Positive Breast Cancer in Patients With Minimal Residual Disease, MIRI TrialRecruitingNCT07191717Phase 2
- A Clinical Study on the Efficacy and Safety of Methotrexate (MTX) or Thiotepa (for MTX Intolerance) or Temozolomide (TMZ) Combined With Orelabrutinib and Selinexor in Relapsed/Refractory Primary or Secondary Central Nervous System Lymphoma（SELINA）RecruitingNCT07191431Not applicable
- Resistance Training and Rapamycin to Enhance Bone Formation in Postmenopausal WomenRecruitingNCT07191353Phase 2
- Adjuvant Abemaciclib for Locoregional Recurrence of HR-positive, HER2-negative Breast Cancer (JCOG2313, AURA)RecruitingNCT07190443Phase 3
- A 52-week Study of Rilzabrutinib Efficacy and Safety Compared to Placebo in Adults Diagnosed With IgG4-related DiseaseRecruitingNCT07190196Phase 3
- A Study of Rocbrutinib in Participants With Relapse or Refractory Non-GCB Diffuse Large B-Cell LymphomaRecruitingNCT07189065Phase 2
- Pucotenlimab Combined With Lenvatinib and Chemotherapy in the Treatment of Advanced, Relapsed/Refractory Hepatoblastoma in ChildrenRecruitingNCT07188311Not applicable
- Modulation of the Bone Immune Microenvironment Following Cabozantinib Treatment of Bone Metastatic Clear Cell Renal Cell Carcinoma: Proof of Concept StudyRecruitingNCT07187869Phase 1
- Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon MutationsRecruitingNCT07185997Phase 3
- Zanzalintinib for Advanced Urothelial Carcinoma Progressing After Prior TherapyNot yet recruitingNCT07185945Phase 2
- Orelabrutinib Combined With Teniposide, Rituximab and Methotrexate for Newly Diagnosed PCNSLRecruitingNCT07185373Phase 2/3
- A Phase 3 Study of Sunvozertinib Versus Placebo as Adjuvant Therapy in Patients With Early-Stage Non-Small Cell Lung Cancer Harboring EGFR Exon 20 Insertion Mutations or PACC Mutations After Radical SurgeryRecruitingNCT07182682Phase 3
- Sequential Chemotherapy With Befotertinib in Non-Small Cell Lung Cancer (NSCLC) Patients With Resistance to Third-Generation EGFR-TKIRecruitingNCT07181499Phase 2
- A Study of Bosmolisib (BR101801) in Participants With R/R PTCL.Not yet recruitingNCT07180771Phase 2
- Continuous or Intermittent Pyrotinib for HER2-positive Advanced Breast CancerRecruitingNCT07180082Phase 2
- Maintenance Therapy in HER2-Positive Unresectable Locally Recurrent or Metastatic Breast Cancer: A Phase II StudyNot yet recruitingNCT07179939Phase 2
- Phase II Study of the Combination of Subcutaneous Blinatumomab and Olverembatinib in Patients With Philadelphia Chromosome (ph)-Positive and/or BCR::ABL1 Positive Acute Lymphoblastic Leukemia (ALL)Not yet recruitingNCT07178912Phase 2
- Efficacy and Safety of LB1410 Plus Lenvatinib With or Without LB4330 in Advanced Recurrent/Metastatic Cervical CancerNot yet recruitingNCT07177716Phase 2/3
- HEM-iSMART E: Capivasertib + Venetoclax + Dexamethasone in Pediatric Patients With Relapsed or Refractory Hematological MalignanciesNot yet recruitingNCT07175415Phase 1/2
- Efficacy and Safety of Masitinib in Combination With SoC Versus Placebo in the Treatment of ALS PatientsNot yet recruitingNCT07174492Phase 3
- A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)RecruitingNCT07174336Phase 3
- Open-Label, Biomarker-Integrated Umbrella Trial for First-Line Treatment of Extensive-stage Small Cell Lung CancerNot yet recruitingNCT07172412Phase 2