Protein Kinase Inhibitors: all 15,766 studies that test it
Page 17 of 158. Open to participants first (2,605), then studies with results posted, then the rest; newest registration first within each.
- CVL237 Tablets in the Treatment of Advanced Solid Tumors With PTEN DeficiencyNot yet recruitingNCT06183736Phase 2
- A Study of Adebrelimab in Combination With Apatinib Gemcitabine and Cisplatin in Biliary Tract MalignanciesRecruitingNCT06181032Phase 1
- Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast CancerRecruitingNCT06179303Phase 2
- A Phase Ib/Ⅱ Study of NTQ1062 in Combination With Fulvestrant in Patients With Advanced HR Positive /HER-2 Negative Breast CancerRecruitingNCT06172322Phase 1
- An Open-label, Phase 1 Study to Determine the Maximum Tolerated Dose of ND-003 in Patients With Advanced Solid CancersEnrolling by invitationNCT06169579Phase 1
- Abemaciclib Dose Escalation to Maintain Intensity (ADE-MI)RecruitingNCT06169371Phase 4
- Cadonilimab Combined With Fruquintinib and SBRT as Athird-line and Posterior Line Treatment in Patients With MSS CRCRecruitingNCT06168786Phase 2
- A Study to Evaluate Zanubrutinib and Tislelizumab in Progressive Lymphoma Post CAR-TRecruitingNCT06167785Phase 2
- A Clinical Study of MK-4208/TERN-701 in Participants With Chronic Myeloid Leukemia (CML) (MK-4208-003/Tern701-1012/CARDINAL)RecruitingNCT06163430Phase 1/2
- Neoadjuvant Trastuzumab, Pertuzumab and Tucatinib Without Chemotherapy in HER2-positive Breast Cancer: the TRAIN-4 StudyRecruitingNCT06162559Phase 1
- Fluzoparib With or Without Apatinib in Platinum-sensitive Relapsed Ovarian Cancer Previously Treated With PARPiNot yet recruitingNCT06161272Phase 2
- Ruxolitinib With De-Intensified HLH-94 for the Treatment of Hemophagocytic Lymphohistiocytosis (HLH)RecruitingNCT06160791Phase 2
- Pacritinib in CMMLRecruitingNCT06159491Phase 1/2
- Binimetinib in Patients With BRAF Fusion-positive Low-grade Glioma or Pancreatic Cancer (Perfume)RecruitingNCT06159478Phase 2
- Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF).RecruitingNCT06159166Phase 1/2
- Cabozantinib With Ifosfamide in Relapsed/Refractory SarcomasRecruitingNCT06156410Phase 1
- Mirdametinib in Histiocytic DisordersRecruitingNCT06153173Phase 2
- Pyrotinib Combined With Capecitabine and Bevacizumab for Patients With HER2 Positive Breast Cancer and Brain MetastasesRecruitingNCT06152822Phase 2
- A Study of Trilaciclib Combined With mFOLFIRINOX in the Treatment of Patients With Advanced Pancreatic CancerRecruitingNCT06151262Phase 2
- Mass Balance Study of TQB3616Not yet recruitingNCT06149611Phase 1
- Adebrelimab Combined With Dalpiciclib and Standard Endocrine Therapy for HR+/HER2 - Advanced Breast CancerRecruitingNCT06149130Phase 2
- Fruquintinib Plus Camrelizumab and Capecitabine as Salvage Therapy After Progression on FOLFOXIRI-based First-line Treatment in Patients With Unresectable/Metastatic Colorectal CancerRecruitingNCT06148402Phase 2
- A Study of HS-10365 in Patients With Advanced or Metastatic RET Fusion-Positive Non-Small Cell Lung CancerRecruitingNCT06147570Phase 2
- Famitinib in Combination With Adebrelimab for the Treatment of Advanced Thyroid CancerNot yet recruitingNCT06146985Phase 2
- Precision Treatment of Recurrent/Metastatic Salivary Gland Carcinoma Guided by Molecular TypingRecruitingNCT06145308Phase 2
- A Prospective Study of Pembrolizumab Combining Chemotherapy in Advanced NSCLC Patients With EGFR Exon 21 Point Mutation.Not yet recruitingNCT06142617Phase 2
- Phase II Clinical Trial to Evaluate the Safety and Efficacy of TQB2450 Injection Combined With Anlotinib Capsule and Chemotherapy in the Treatment of Immunoresistant Advanced Non-small Cell Lung CancerRecruitingNCT06141226Phase 2
- Apatinib Combined With Camrelizumab in Treating Participants With Advanced ChordomaRecruitingNCT06140732Phase 2
- The Efficacy and Safety of Lenvatinib Combined With Sindilimab and Nab-paclitaxel in the First-line Treatment for Recurrent and Metastatic Triple Negative Breast Cancer: a Phase Ib/IIa Clinical Trial.Not yet recruitingNCT06140576Phase 1/2
- RADIANT: Pre-op Radiation With Abemaciclib and LetrozoleRecruitingNCT06139107Phase 1
- A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)RecruitingNCT06136559Phase 3
- A Study of the Zanubrutinib Given in Combination With Bendamustine and Rituximab in (Elderly or TP53 Alterations or Chemotherapy Intolerance) Patients With Newly Diagnosed Mantle Cell LymphomaRecruitingNCT06136351Phase 2
- Combination Therapy of HAIC, Surufatinib and Tislelizumab for Unresectable or Metastatic Biliary Tract CancerNot yet recruitingNCT06134193Phase 2
- A Study of Simmitinib Plus SG001 in Advanced Solid TumorsNot yet recruitingNCT06132217Phase 1/2
- Phase I Study of JYP0322 in ROS1 Fusion-Positive Solid TumorsRecruitingNCT06128148Phase 1
- Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic SyndromeRecruitingNCT06128070Phase 2
- Combination of Everolimus and 177Lu-DOTATATE in the Treatment of Grades 2 and 3 Refractory Meningioma: a Phase IIb Clinical TrialRecruitingNCT06126588Phase 2
- Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)RecruitingNCT06126276Phase 2
- Tucidinostat Plus Apatinib for Advanced OsteosarcomaNot yet recruitingNCT06125171Phase 2
- A Study of WX390 Combined With Toripalimab in Patients With Advanced Gastric-type Endocervical Adenocarcinoma With STK11 MutationsRecruitingNCT06124963Phase 2
- A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)RecruitingNCT06124157Phase 2
- A Clinical Trial of TQ05105 Tablets Combined With TQB3617 Capsules in the Treatment of Myelofibrosis (MF)RecruitingNCT06122831Phase 1/2
- Precision Cancer Therapy in Rare CancersRecruitingNCT06119789Phase 2
- Evaluation of the Efficacy and Safety of Methylprednisolone Combined With the JAK Inhibitors in the Treatment of Toxic Epidermal NecrolysisRecruitingNCT06119490Early Phase 1
- Clinical Study of Fruquintinib Combined With Raltitrexed in the Treatment of Metastatic Colorectal CancerRecruitingNCT06118762Phase 4
- A Study of WX390 Combined With Toripalimab in Patients With Advanced Solid TumorsRecruitingNCT06117566Phase 1/2
- A Study of WX390 in Patients With Advanced Solid TumorsRecruitingNCT06117540Phase 2
- Baricitinib in the Treatment of Refractory Axial Spondyloarthritis Patients: A Comparison With TofacitinibRecruitingNCT06114407Phase 2
- Palbociclib and Pembrolizumab in SarcomaRecruitingNCT06113809Phase 1
- ToFAcitinib in Early Active Axial SpondyloarThritis:RecruitingNCT06112665Phase 4
- Tirbanubulin (Klisiry®) in the Treatment of Basal Cell CarcinomaRecruitingNCT06112522Phase 2
- Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)RecruitingNCT06112340Phase 2/3
- A Phase 2 Study of ABSK021 in Patients With Advanced Pancreatic CancerRecruitingNCT06111274Phase 2
- A Study of HS-10241 Combined With Almonertinib Versus Platinum-based Chemotherapy in Treatment of Advanced NSCLC With MET Amplification After Failure of EGFR-TKI TherapyNot yet recruitingNCT06110663Phase 3
- A Study of Surufatinib in the Treatment of Advanced Soft Tissue SarcomaNot yet recruitingNCT06110650Not applicable
- The Efficacy and Safety of LMV-12 Combined With Osimertinib in NSCLCRecruitingNCT06109558Phase 1/2
- A Trial to Evaluate the Safety and Efficacy of SM-020 Gel 1.0% in Subjects With Seborrheic KeratosisRecruitingNCT06108024Phase 2
- Dalpiciclib Plus AI (Neoadjuvant Endocrine Therapy) Compared With Neoadjuvant Chemotherapy in Early Breast Cancer （EBC）RecruitingNCT06107673Phase 2
- Lazertinib & Tepotinib for EGFR Mutant NSCLC in MET Overexpressed or Amplified Who Progressed After Lazertinib TreatmentRecruitingNCT06106802Phase 2
- Phase I/II Open Label Study of Belumosudil Mesylate Alone, and in Combination With Dexamethasone, in Patients With Relapsed/Refractory Multiple MyelomaRecruitingNCT06105554Phase 1/2
- Global Trial in APG2575 for Patients With CLL/SLLRecruitingNCT06104566Phase 3
- Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal CancerRecruitingNCT06102902Phase 1
- Dalpiciclib Isethionate Tablets Combined With Abiraterone Acetate Tablets (I) and Prednisone Tablets (AA-P) Versus Placebo Combined With AA-P in Treatment of High-volume, Metastatic, Hormone-sensitive Prostate Cancer (mHSPC)Not yet recruitingNCT06099990Phase 1
- Efficacy and Safety of Vedolizumab Combined With Upadacitinib in Patients With Ulcerative ColitisRecruitingNCT06095596Not applicable
- A Study of Alisertib in Patients With Extensive Stage Small Cell Lung CancerRecruitingNCT06095505Phase 2
- Clinical Study of Fruquintinib Combined With Sintilimab and XELOX Regimen in the Treatment of Advanced CancerNot yet recruitingNCT06094868Phase 2
- Surufatinib Plus Cadonilimab in Patients With Unresectable or Metastatic Bile Duct AdenocarcinomaRecruitingNCT06092645Phase 2
- Lorlatinib as the First-line Treatment in China Advanced ALK+ NSCLCRecruitingNCT06092086Phase 2
- Hemorrhagic Brainstem Cavernous Malformations Treatment With Sirolimus: aSingle Centre, Randomized, Placebo-controlled Pilot TrialRecruitingNCT06091332Phase 2
- Imatinib to Increase RUNX1 Activity in Participants With Germline RUNX1 DeficiencyRecruitingNCT06090669Phase 1
- A Study to Evaluate Sintilimab Plus Lenvatinib as Adjuvant Therapy in Hepatocellular Carcinoma With Portal Vein Tumor Thrombosis (PVTT) After Surgical ResectionNot yet recruitingNCT06089382Phase 3
- TGRX-678 US Phase I for Chronic Myelogenous Leukemia PatientsRecruitingNCT06088888Phase 1
- A-RGEMOX in the Treatment of Early Relapsed/Refractory DLBCLRecruitingNCT06086197Phase 2
- Trastuzumab Deruxtecan(T-DXd) and Afatinib Combination in HER2-low Advanced Gastric CancerRecruitingNCT06085755Phase 1/2
- Intestinal & Multivisceral Transplantation for Unresectable Mucinous Carcinoma Peritonei (TRANSCAPE)Not yet recruitingNCT06084780Phase 2
- Olverembatinib Plus Venetoclax and Dexamethasone for Treatment-naïve Ph+ Acute Lymphoblastic LeukemiaRecruitingNCT06082934Phase 1/2
- Efficacy and Safety of Orelabrutinib Combined With Rituximab Versus Lenalidomide Combined With Rituximab in Patients With Relapsed/Refractory Marginal Zone LymphomaRecruitingNCT06082102Phase 3
- A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft DysfunctionRecruitingNCT06082037Phase 3
- Fluzoparib Combined With Apatinib in Relapsed Ovarian Carcinoma Maintenance TreatmentNot yet recruitingNCT06081595Phase 2
- Curcumin Supplementation in Cervical CancerRecruitingNCT06080841Not applicable
- MAP-guided Preemptive Therapy of aGvHD by RuxolitinibNot yet recruitingNCT06075225Phase 2
- A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian CancerRecruitingNCT06072781Phase 3
- A Phase 0/1 Study of BDTX-1535 in Recurrent High-Grade Glioma (rHGG) and Newly Diagnosed Glioblastoma (nGBM) Participants With EGFR Alterations or FusionsRecruitingNCT06072586Early Phase 1
- Nintedanib Plus EGFR TKI In EGFR-mutated Non-small Cell Lung Cancer PatientsRecruitingNCT06071013Phase 1/2
- bTAE-HAIC Combined With Lenvatinib and Sintilimab for Infiltrative Hepatocellular CarcinomaRecruitingNCT06070636Not applicable
- Osimertinib, Cetuximab, and Tucatinib for the Treatment of EGFR-Mutant Stage IV or Recurrent Non-small Lung Cell CancerNot yet recruitingNCT06067776Phase 1
- Exploring Cancer-Associated Thromboembolism Prognosis Biomarkers and PolymorphismsRecruitingNCT06065592Phase 1
- Baricitinib for Moderate and Severe Traumatic Intracerebral Hemorrhage/ContusionsRecruitingNCT06065046Phase 2
- Study of EGFR TKI in Patients With Advanced NSCLC Harbouring EGFR MutationsRecruitingNCT06062823Phase 2
- Study of Anlotinib in Patients With Radioiodine Refractory Differentiated Thyroid CancerNot yet recruitingNCT06062563Not applicable
- Elacestrant vs Elacestrant Plus a CDK4/6 Inhibitor in Patients With ERpositive/HER2-negative Advanced or Metastatic Breast CancerRecruitingNCT06062498Phase 2
- bTAE-HAIC Combined With System Therapy for Intermediate-advanced Huge HCCRecruitingNCT06061276Not applicable
- Randomized Trial in Adult de Novo Ph Positive ALL With Chemotherapy, Imatinib or Ponatinib, Blinatumomab and SCTRecruitingNCT06061094Phase 2
- A Study of a Plant-Based Diet and Dietary Supplements in People With Smoldering Multiple Myeloma (SMM) or Monoclonal Gammopathy of Undetermined Significance (MGUS)RecruitingNCT06055894Not applicable
- Advancing Transplantation Outcomes in ChildrenRecruitingNCT06055608Phase 2
- Acalabrutinib, Obinutuzumab, and Glofitamab for the Treatment of Relapsed or Refractory Mantle Cell LymphomaRecruitingNCT06054776Phase 2
- Neoadjuvant and Adjuvant Targeted Treatment in NSCLC With BRAF V600 or MET Exon 14 MutationsNot yet recruitingNCT06054191Phase 2
- Phase 2 Study of Combination Tivozanib and Nivolumab in Advanced Non-Clear Cell Renal Cell CarcinomaRecruitingNCT06053658Phase 2
- Contribution of UGT2B17 to the Pharmacokinetics of DiclofenacRecruitingNCT06053411Early Phase 1
- Phase II Study of Pacritinib in Kaposi Sarcoma Herpesvirus (KSHV)-Associated Multicentric Castleman Disease and KSHV-Associated Inflammatory Cytokine Syndrome (KICS)RecruitingNCT06052618Phase 2