Protein Kinase Inhibitors: all 15,766 studies that test it

Page 150 of 158. Open to participants first (2,605), then studies with results posted, then the rest; newest registration first within each.

• Therapeutic Strategy in Advanced Bronchioloalveolar CarcinomaCompletedNCT00384826Phase 2
• A Phase l/ll Study of AMN107 in Adult Patients With Glivec-intolerant CML or Relapsed-refractory Ph+ALLCompletedNCT00384228Phase 1/2
• Safety/Tolerability Study of AV-412 in Subjects With Refractory or Relapsed Solid Tumor MalignanciesTerminatedNCT00381654Phase 1
• HKI-272 Ketoconazole Drug Interaction StudyCompletedNCT00380328Phase 1
• Study of SB681323 and Prednisolone on Biomarkers in COPD (Chronic Obstructive Pulmonary Disease) PatientsCompletedNCT00380133Phase 1
• Lapatinib and Radiation Therapy in Treating Patients With Locally Recurrent or Chemotherapy-Refractory Locally Advanced or Metastatic Breast CancerCompletedNCT00379509Phase 1
• Sunitinib in Treating Patients With Recurrent or Persistent Leiomyosarcoma of the UterusCompletedNCT00378911Phase 2
• Alvocidib in Treating Patients With B-Cell Chronic Lymphocytic Leukemia or Small Lymphocytic LymphomaTerminatedNCT00377104Phase 1
• STI 571 (GLIVEC) in the Treatment of Adult Acute Lymphoblastic LeukemiaCompletedNCT00376467Phase 2
• Anti-Estrogen Therapy for Hereditary Hemorrhagic Telangiectasia A Double-Blind Placebo-Controlled Clinical TrialCompletedNCT00375622Phase 2
• Phase I Study of Gemcitabine, Sorafenib and Radiotherapy in Patients With Unresectable Pancreatic CancerCompletedNCT00375310Phase 1
• Rapamycin With Grapefruit Juice for Advanced MalignanciesCompletedNCT00375245Phase 1
• Study to Evaluate Safety and Efficacy of Early Calcineurin Inhibitor Withdrawal in Primary Renal AllograftsCompletedNCT00374647Phase 4
• CT-322 in Treating Patients With Advanced Solid Tumors and Non-Hodgkin's LymphomaCompletedNCT00374179Phase 1
• Everolimus in Combination With Cyclosporine A and Prednisolone for the Treatment of Graft Versus Host DiseaseTerminatedNCT00373815Phase 1
• Efficacy of Sorafenib Added to Standard Primary Therapy in Elderly Patients With Newly Diagnosed AMLCompletedNCT00373373Phase 2
• AZD6244 vs. Capecitabine (Xeloda®) in Patients With Advanced or Metastatic Pancreatic Cancer, Who Have Failed First Line Gemcitabine TherapyCompletedNCT00372944Phase 2
• Dose-Finding Study Of CP-675,206 And SU011248 In Patients With Metastatic Renal Cell CarcinomaCompletedNCT00372853Phase 1
• AZD6244 Versus Pemetrexed (Alimta®) in Patients With Non-small Cell Lung Cancer, Who Have Failed One or Two Prior Chemotherapy RegimenCompletedNCT00372788Phase 2
• High Dose Gefitinib for the Treatment of Carcinomatous Meningitis in Adult Patients With Non-Small Cell Lung Cancer and Known or Suspected EGFR MutationsCompletedNCT00372515Phase 1
• Efficacy and Safety of Imatinib and Vinorelbine in Patients With Advanced Breast CancerCompletedNCT00372476Phase 4
• Efficacy Study of Oral Seliciclib to Treat Non-Small Cell Lung CancerTerminatedNCT00372073Phase 2
• Phase-II Study of SU011248 (Sunitinib)in Male Patients With Relapsed or Cisplatin-Refractory Germ Cell CancerCompletedNCT00371553Phase 2
• GW572016 Combined With Trastuzumab For The Treatment Of Previously Trastuzumab-Treated Breast CancerCompletedNCT00371488Phase 1
• A Phase I Study of Pazopanib in Adult Patients With Liver CancerCompletedNCT00370513Phase 1
• A Study to Test the Safety and Efficacy of Erlotinib Plus Bevacizumab to Treat Advanced Thymoma and Thymic CancerCompletedNCT00369889Phase 2
• A Phase 2 Trial of AMG 706 or Bevacizumab in Combination With Chemo for Advanced NSCLCTerminatedNCT00369070Phase 2
• Sirolimus in Treating Patients With Metastatic or Unresectable Solid TumorsCompletedNCT00368914Phase 1
• Study Evaluating HKI-272 Administered to Healthy SubjectsCompletedNCT00366600Phase 1
• Study of XL647 in Subjects With Non-Small-Cell Lung CancerCompletedNCT00364780Phase 2
• Phase I Study of Triciribine Phosphate Monohydrate (TCN-PM, VD-0002) in Adult Subjects With Metastatic CancerCompletedNCT00363454Phase 1
• A Two-way Crossover Study Of The Effect Of Food On The Pharmacokinetics Of Pazopanib In Cancer PatientsCompletedNCT00363194Phase 1
• SU011248 in Advanced Hepatocellular CarcinomaCompletedNCT00361309Phase 2
• SU011248 in Combination With Irinotecan and Cetuximab as a Second Line Regimen for Stage IV Colorectal CancerTerminatedNCT00361244Phase 1/2
• An Open Label Treatment Extension Study of AMG 706TerminatedNCT00360867Phase 2
• Erlotinib Alone or in Combination With Radiation Therapy in Treating Young Patients With Refractory or Relapsed Malignant Brain Tumors or Newly Diagnosed Brain Stem GliomaStatus unknownNCT00360854Phase 1
• Pharmacokinetics And Pharmacodynamics Of Lapatinib In Two Dosing Regimens In Treatment-naive Patients With Breast CancerCompletedNCT00359190Phase 1
• The Effect of Macugen in Patients With Chronic, Post-Operative Cystoid Macular EdemaTerminatedNCT00358423Phase 1/2
• Chronic Plaque Psoriasis Study With Topical Formulation Of GW786034CompletedNCT00358384Phase 1
• Trial of PTK787/ZK 222584 Plus PaclitaxelTerminatedNCT00358163Phase 1
• Bevacizumab and Sunitinib in Treating Patients With Solid TumorsCompletedNCT00357318Phase 1
• A Study of AMG 706 or Bevacizumab, in Combination With Paclitaxel Chemotherapy, as Treatment for Breast CancerTerminatedNCT00356681Phase 2
• Vascular and Skeletal Protective Effects of Genistein in Postmenopausal WomenCompletedNCT00355953Phase 2/3
• Immunosuppression in Patients Undergoing Liver Transplantation for Hepatocellular CarcinomaCompletedNCT00355862Phase 3
• Bevacizumab and Erlotinib Followed by Cisplatin or Carboplatin and Gemcitabine in Treating Patients With Newly Diagnosed or Recurrent Stage IIIB or Stage IV NSCLCCompletedNCT00354549Phase 2
• Imatinib in Combination With Dacarbazine and Capecitabine in Medullary Thyroid CarcinomaTerminatedNCT00354523Phase 1/2
• A Clinical Trial to Explore the Safety and Efficacy of Injections of Macugen When Given Every 6 Weeks in Subjects With AMDStatus unknownNCT00354445Phase 4
• Imatinib Mesylate and Temozolomide in Treating Patients With Malignant GliomaCompletedNCT00354068Phase 1
• Safety and Tolerability Study of INNO-406 to Treat Chronic Myeloid Leukemia or Acute Lymphocytic LeukemiaCompletedNCT00352677Phase 1
• S0528 Lapatinib and Everolimus in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's LymphomaCompletedNCT00352443Phase 1
• BCG With or Without Gefitinib in Treating Patients With High-Risk Bladder CancerTerminatedNCT00352079Phase 3
• Study of XL820 Given Orally Daily to Subjects With Solid TumorsCompletedNCT00350831Phase 1
• Study of Dasatinib in Imatinib Resistant or Intolerant Subjects With Chronic or Advanced Phase CML or Philadelphia Chromosome Positive ALLWithdrawnNCT00349518Phase 2/3
• TORCH: A Study of Tarceva or Chemotherapy for the Treatment of Advanced Non Small Cell Lung CancerCompletedNCT00349219Phase 3
• Sorafenib and Temsirolimus in Treating Patients With Metastatic, Recurrent, or Unresectable MelanomaCompletedNCT00349206Phase 1
• Macugen to Prevent Worsening of Macular Edema Following Cataract Surgery in DiabeticsTerminatedNCT00346983Phase 1/2
• Sirolimus (Rapamune®) for Autosomal Dominant Polycystic Kidney Disease (ADPKD)CompletedNCT00346918Phase 3
• Dasatinib in Treating Patients With Chronic Myelogenous Leukemia or Acute Lymphoblastic LeukemiaCompletedNCT00345826Phase 1
• Presurgical Therapy With Lapatinib to Explore Molecular Determinants of Response to EGFR/erbB2 Targeted TherapyWithdrawnNCT00343759Phase 2
• First-Line EGFR-1 Tyrosine Kinase Inhibition in Patients With NSCLC With Mutant EGFR GeneStatus unknownNCT00339586Phase 2
• AZD1152 in Patients With Advanced Solid MalignanciesCompletedNCT00338182Phase 1
• Randomised Study to Compare the Efficacy of AZD6244 vs TMZCompletedNCT00338130Phase 2
• A Study of the Safety and Efficacy of Tarceva in Patients With First Relapse of Grade IV Glioma (Glioblastoma Multiforme)CompletedNCT00337883Phase 2
• Phase II Trial of RAD001 in Refractory Colorectal CancerCompletedNCT00337545Phase 2
• Study of BMS-354825 in Subjects With CML Who Are Resistant to or Intolerant of Imatinib or Ph+All in JapanCompletedNCT00337454Phase 1/2
• A Study of the mTOR Inhibitor Rapamycin (Rapamune, Sirolimus) in Combination With Abraxane in Advanced Solid CancersTerminatedNCT00337376Phase 1
• Study of XL647 Administered Orally Daily to Patients With Solid TumorsCompletedNCT00336765Phase 1
• PHA-739358 in Treating Patients With Chronic Myelogenous Leukemia That Relapsed After Imatinib Mesylate or c-ABL TherapyStatus unknownNCT00335868Phase 2
• Sunitinib Malate With Hormonal Ablation for Patients Who Will Have ProstatectomyActive, not recruitingNCT00329043Phase 2
• A Phase I Study of BMS-690514 in Patients With Advanced or Metastatic Solid TumorsCompletedNCT00329004Phase 1
• Comparing Imatinib Standard Dose With Imatinib High Dose Induction in Pretreated Chronic Myeloid Leukemia (CML) Patients in Chronic PhaseStatus unknownNCT00327262Phase 3
• AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS TumorsCompletedNCT00326664Phase 1
• Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)CompletedNCT00326339Phase 2
• Pharmacokinetic Study on the Combination of Everolimus-TacrolimusStatus unknownNCT00325325Phase 2
• Vorinostat and Alvocidib in Treating Patients With Advanced Solid TumorsCompletedNCT00324480Phase 1
• Gemcitabine With or Without Imatinib Mesylate in Treating Patients With Metastatic or Unresectable Kidney CancerTerminatedNCT00323791Phase 2
• Study of XL999 in Patients With Acute Myeloid Leukemia (AML)TerminatedNCT00322673Phase 2
• A Clinical Trial to Explore Safety and Efficacy of Different Doses of Pegaptanib Sodium, Compared to Sham, in Patients With Wet AMD.CompletedNCT00321997Phase 2/3
• Trial Of Erlotinib With Or Without PF-3512676 In Advanced Non Small Cell Lung CancerCompletedNCT00321815Phase 2
• AZD2171 in Treating Patients With Relapsed or Refractory B-Cell Chronic Lymphocytic LeukemiaCompletedNCT00321724Phase 2
• AZD2171 to Treat Children and Adolescents With Solid Tumors or Acute Myelogenous LeukemiaCompletedNCT00321581Phase 1
• SB-681323 In Subjects With Rheumatoid ArthritisCompletedNCT00320450Phase 2
• Vinflunine and Erlotinib or Pemetrexed in Treating Patients With Unresectable or Metastatic Solid TumorsCompletedNCT00320073Phase 1
• Sirolimus and Cyclosporine for Treatment-Resistant Aplastic AnemiaStatus unknownNCT00319878Phase 1/2
• Second-Line Irinotecan or Gefitinib in Docetaxel Pretreated NSCLCStatus unknownNCT00319800Phase 2
• Combination Casodex® and Iressa™ in Locally Advanced Prostate CancerCompletedNCT00319787Phase 2
• Antithymocyte Globulin and Sirolimus in Treating Patients With Relapsed Multiple MyelomaCompletedNCT00317798Phase 1
• Maximum Tolerated Dose of Lapatinib When Given With Carboplatin for Recurrent Ovarian CancerTerminatedNCT00317434Phase 1
• Dasatinib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia That Did Not Respond to Imatinib MesylateCompletedNCT00316953Phase 1
• Lapatinib and Doxorubicin Hydrochloride Liposome in Treating Patients With Metastatic Breast CancerCompletedNCT00316875Phase 1
• Temsirolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma MultiformeCompletedNCT00316849Phase 1
• Lapatinib/Carboplatin/Paclitaxel in Previously Treated Ovarian or Breast Cancer PatientsCompletedNCT00316407Phase 1/2
• Pilot Study of Imatinib (Gleevec) as Treatment for Advanced Thymic CarcinomaCompletedNCT00314873Phase 1
• Lapatinib and Paclitaxel in Treating Patients With Advanced Solid TumorsCompletedNCT00313599Phase 1
• A Clinical Trial to Explore the Safety and Efficacy of Three Different Doses of Pegaptanib Sodium in Patients With Wet Age-Related Macular Degeneration (AMD)TerminatedNCT00312351Phase 4
• Gefitinib, Docetaxel, and Radiation Therapy in Treating Patients With Stage III Non-Small Cell Lung CancerCompletedNCT00310154Phase 1
• Randomized Study Comparing Tamoxifen vs. Tamoxifen + Aminoglutethimide in Postmenopausal Receptor-positive PatientsCompletedNCT00309491Phase 3
• Randomized Study Comparing CMF and Goserelin + Tamoxifen in Premenopausal Receptor-positive PatientsCompletedNCT00309478Phase 3
• Pilot Study to Investigate a Steroid Free Immunosuppressive Regimen for Renal Transplant RecipientsCompletedNCT00306397Phase 4
• CA 125 Levels in Treating Patients With Relapsed Advanced Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer Who Are Receiving TamoxifenStatus unknownNCT00305838Phase 2

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