Protein Kinase Inhibitors: all 15,766 studies that test it
Page 141 of 158. Open to participants first (2,605), then studies with results posted, then the rest; newest registration first within each.
- Study of Erlotinib in Combination With DasatinibCompletedNCT00895128Phase 1
- Safety Study to Determine the Maximum Tolerated Dose, Pharmacokinetics and Pharmacodynamics of Oral MP470, a Multitargeted Tyrosine Kinase Inhibitor, in Patients With Solid MalignanciesCompletedNCT00894894Phase 1
- Study Evaluating Sorafenib Added to Standard Primary Therapy in Patients With Newly Diagnosed Acute Myeloid Leukemia Less Than 60 Years of AgeCompletedNCT00893373Phase 2
- Letrozole, Anastrozole, Exemestane, or Tamoxifen Citrate in Treating Postmenopausal Women With Breast CancerCompletedNCT00893061Phase 3
- Everolimus and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastasis From Non-Small Cell Lung CancerTerminatedNCT00892801Phase 1
- Sorafenib-RT in Treating Hepatocellular Carcinoma (SHEP)CompletedNCT00892658Phase 1
- Sorafenib-RT Treatment for Liver Metastasis (SLIM)CompletedNCT00892424Phase 1/2
- Study of Dasatinib and All-Trans Retinoic Acid for Relapsed/Refractory and/or Elderly Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic SyndromeCompletedNCT00892190Phase 1
- Nutritional and Contractile Regulation of Muscle GrowthCompletedNCT00891696Phase 1
- Study of Pemetrexed Versus Gefitinib in Patients With Locally Advanced or Metastatic Non Small Cell Lung Cancer Who Have Previously Received Platinum-Based Chemotherapy Without Epidermal Growth Factor Receptor (EGFR) MutationsCompletedNCT00891579Phase 2
- Palliative Radiofrequency Ablation in Metastatic Renal Cell Carcinoma PatientsCompletedNCT00891475Phase 1/2
- Dose-escalation Study of Oral CX-4945Status unknownNCT00891280Phase 1
- Gossypol, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by SurgeryCompletedNCT00891072Phase 1
- Sunitinib Malate in Treating HIV-Positive Patients With Cancer Receiving Antiretroviral TherapyCompletedNCT00890747Phase 1
- Safety and Efficacy of ProHema Modulated Umbilical Cord Blood Units in Subjects With Hematologic Malignancies.CompletedNCT00890500Phase 1
- Safety Study of Calcineurin-Inhibitor-Free Immunosuppression After Liver TransplantationStatus unknownNCT00890253Phase 2
- A Study Evaluating Intermittent and Continuous OSI-906 and Weekly Paclitaxel in Patients With Recurrent Epithelial Ovarian Cancer (and Other Solid Tumors)CompletedNCT00889382Phase 1/2
- Study to Evaluate the Effects of Sorafenib if Combined With Chemotherapy (FOLFOX6 or FOLFIRI) in the Second-Line Treatment of Colorectal CancerTerminatedNCT00889343Phase 2
- Curcumin in Pediatric Inflammatory Bowel DiseaseCompletedNCT00889161Phase 1
- Sorafenib in Relapsed High Grade OsteosarcomaCompletedNCT00889057Phase 2
- Efficacy of Topotecan and Lapatinib in Early Recurrent Ovarian or Peritoneal CancerTerminatedNCT00888810Phase 2
- Sorafenib as Adjuvant to Radioiodine Therapy in Non-Medullary Thyroid CarcinomaCompletedNCT00887107Phase 2
- A Study of Sunitinib in Recurrent and/or Metastatic Adenoid Cystic Carcinoma of the Salivary GlandsCompletedNCT00886132Phase 2
- A Dose Finding Study of AEB071 Assessing Psoriasis Area and Severity Index in Patients With Plaque PsoriasisCompletedNCT00885196Phase 2
- Gemcitabine, Capecitabine, and Erlotinib in Treating Patients With Advanced Pancreatic CancerCompletedNCT00885066Phase 1
- Trial of PM02734 Administered in Combination With Erlotinib in Patients With Advanced Malignant Solid TumorsCompletedNCT00884845Phase 1
- Ixabepilone and Sunitinib Malate in Treating Patients With Progressive Advanced Solid TumorsCompletedNCT00884676Phase 1
- Individualized Treatment Based on Epidermal Growth Factor Receptor Mutations and Level of BRCA1 Expression in Advanced AdenocarcinomaCompletedNCT00883480Not applicable
- XIAP Antisense AEG35156 in Combination With Sorafenib in Patients With Advanced Hepatocellular Carcinoma (HCC)CompletedNCT00882869Phase 1/2
- Genistein in Treating Patients With Pancreatic Cancer That Can Be Removed by SurgeryWithdrawnNCT00882765Phase 2
- Study To Evaluate Safety and Efficacy of P276-00 in Subjects With Refractory Multiple MyelomaCompletedNCT00882063Phase 1/2
- Safety of MP470 in Combination With Standard-of-Care Chemotherapy Regimens to Treat Solid TumorsCompletedNCT00881166Phase 1
- Trial of Imatinib (Gleevec®) in Selected Patients With Metastatic MelanomaCompletedNCT00881049Phase 2
- Cixutumumab and Temsirolimus in Treating Younger Patients With Solid Tumors That Have Recurred or Not Responded to TreatmentCompletedNCT00880282Phase 1
- A Study to Determine the Effect of Food on the Pharmacokinetics of Oral AZD8931 TabletsCompletedNCT00879346Phase 1
- GDC-0449 and Erlotinib Hydrochloride With or Without Gemcitabine Hydrochloride in Treating Patients With Metastatic Pancreatic Cancer or Solid Tumors That Cannot Be Removed by SurgeryActive, not recruitingNCT00878163Phase 1
- Subconjunctival Sirolimus for the Treatment of Autoimmune Active Anterior UveitiCompletedNCT00876434Phase 1
- A Study of GDC-0941 in Patients With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma for Which Standard Therapy Either Does Not Exist or Has Proven Ineffective or IntolerableCompletedNCT00876122Phase 1
- A Study of GDC-0941 in Participants With Locally Advanced or Metastatic Solid Tumors for Which Standard Therapy Either Does Not Exist or Has Proven Ineffective or IntolerableCompletedNCT00876109Phase 1
- Combination of Sorafenib and Vorinostat in Poor-risk Acute Myelogenous Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)CompletedNCT00875745Phase 1
- Open-Label Study to Determine the Maximum Tolerated Oral Dose of the Kinase Inhibitor CEP-11981 in Patients With Advanced CancerCompletedNCT00875264Phase 1
- Sorafenib in Treating Patients With Angiosarcoma That is Locally Advanced, Metastatic, or Unable to Be Removed by SurgeryCompletedNCT00874874Phase 2
- Rapamycin in Relapsed Acute Lymphoblastic LeukemiaCompletedNCT00874562Phase 1
- Erlotinib Versus Gemcitabine/Carboplatin in Chemo-naive Stage IIIB/IV Non-Small Cell Lung Cancer Patients With Epidermal Growth Factor Receptor (EGFR) Exon 19 or 21 MutationCompletedNCT00874419Phase 3
- Trial to Evaluate the Efficacy and Safety of Tarceva and Capecitabine in Advanced Pancreatic Cancer PatientsCompletedNCT00873353Phase 2
- Ursodiol, Combination Chemotherapy, and Bevacizumab in Treating Patients With Stage IV Colorectal CancerCompletedNCT00873275Phase 1
- Panobinostat and Sorafenib in Treating Patients With Liver Cancer That is Metastatic and/or Cannot Be Removed by SurgeryTerminatedNCT00873002Phase 1
- Study of Dasatinib and Bendamustine in Chronic Lymphocytic LeukemiaWithdrawnNCT00872976Phase 1
- PHA-739358 for the Treatment of Multiple MyelomaTerminatedNCT00872300Phase 2
- A Study of the Effectiveness and Safety of AMG 386 and Sorafenib to Treat Advanced or Inoperable Hepatocellular CancerCompletedNCT00872014Phase 2
- Phase 1 Weekly Dosing of SCH 727965 in Patients With Advanced Cancer (Study P04629AM6)CompletedNCT00871663Phase 1
- SCH 727965 in Patients With Mantle Cell Lymphoma or B-Cell Chronic Lymphocytic Leukemia (Study P04715)TerminatedNCT00871546Phase 2
- Study of Combination of Metronomic Oral Vinorelbine and Sorafenib in Patients With Advanced Non-small Cell Lung CancerCompletedNCT00870532Phase 1
- Everolimus in Treating Patients With Relapsed or Metastatic Endometrial CancerCompletedNCT00870337Phase 2
- A Dose-Finding Study of E7050 Administered Orally to Patients With Advanced Solid TumorsCompletedNCT00869895Phase 1
- External-Beam Radiation Therapy, Capecitabine, and Sorafenib in Treating Patients With Locally Advanced Rectal CancerCompletedNCT00869570Phase 1/2
- Efficacy and Safety of 5-day Dosing of ON 01910.Na in Intermediate-1,-2, or High Risk Myelodysplastic Syndrome (MDS)WithdrawnNCT00867061Phase 1/2
- A Study of Dasatinib in Patients With Imatinib Resistant or Intolerant Chronic Myeloid LeukemiaCompletedNCT00866736Phase 2
- Study of Pazopanib and Paclitaxel in Advanced Non-small Cell Lung CancerCompletedNCT00866528Phase 1
- Masitinib in Relapse or Refractory Multiple Myeloma With t(4/14) Translocation Expressing or Not FGFR3CompletedNCT00866138Phase 2
- Sunitinib Tumor Levels in Patients Not on Enzyme-Inducing Anti-Epileptic Drugs Undergoing Debulking Surgery for Recurrent GlioblastomaCompletedNCT00864864Early Phase 1
- Study Evaluating The Potential Effect Of Rifampin On The Pharmacokinetics Of NeratinibCompletedNCT00864487Phase 1
- A Study of ARRY-334543 and Gemcitabine in Patients With Advanced Cancer and Pancreatic CancerCompletedNCT00862524Phase 1/2
- A Study of Decitabine in Combination With Escalating Doses of Rapamycin in Patients With Relapsed or Refractory Acute Myeloid LeukemiaCompletedNCT00861874Phase 1
- Safety of ON 01910.Na and Irinotecan or ON 01910.Na and Oxaliplatin in Patients With HepatomaCompletedNCT00861783Phase 1
- A Pilot Study of the Safety and Activity of Escalating Doses of ON 01910.Na in Patients With Relapsed Mantle Cell Lymphoma, Multiple Myeloma, Chronic Lymphocytic Leukemia, and Related Lymphoid MalignanciesCompletedNCT00861510Phase 1
- To Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 386 When Used in Combination With AMG 706, Bevacizumab, Sorafenib, or Sunitinib.CompletedNCT00861419Phase 1
- Safety Study of ON 01910.Na in Combination With Irinotecan or OxaliplatinCompletedNCT00861328Phase 1
- VEG111485: A QTc Study of PazopanibCompletedNCT00861029Phase 1
- Study Evaluating The Potential Effect Of Multiple Doses Of Neratinib On The Pharmacokinetics Of A Single Dose Of DigoxinCompletedNCT00860223Phase 1
- Oral Sirolimus for In-Stent RestenosisCompletedNCT00859183Phase 4
- Pharmacodynamic Study of Axitinib in Patients With Advanced Solid MalignanciesCompletedNCT00859118Phase 1
- First Line Hepato Cellular Carcinoma (HCC)CompletedNCT00858871Phase 3
- Intermittent Imatinib Treatment in Chronic Myeloid Leukemia and Philadelphia Chromosome (Ph+CML) Patients Who Achieved a Complete Cytogenetic Response (CCgR) on Standard Imatinib TherapyCompletedNCT00858806Phase 2
- Radiation Therapy (IMRT) + RAD001 (Everolimus) + Cisplatin for Patients With Head and Neck CancerCompletedNCT00858663Phase 1
- Safety Study of Calcineurin Inhibitor Free GvHD Prophylaxis in Allogeneic Stem Cell TransplantationStatus unknownNCT00856505Phase 1/2
- Everolimus in Treating Women With Breast Cancer That Can Be Removed by SurgeryWithdrawnNCT00855114Phase 2
- Study of 72-Hour Infusion of ON 01910.Na in Patients With MDS or AMLCompletedNCT00854945Phase 1/2
- Phase I Study of ON 01910.Na in Refractory Leukemia or Myelodysplastic Syndrome (MDS)CompletedNCT00854646Phase 1
- A Study Evaluating GDC-0980 Administered Once Daily in Patients With Refractory Solid Tumors or Non-Hodgkin's LymphomaCompletedNCT00854152Phase 1
- A Study Evaluating GDC-0980 Administered Once Weekly in Patients With Refractory Solid Tumors or Non-Hodgkin's LymphomaCompletedNCT00854126Phase 1
- Phase I Study to Assess Absorption, Metabolism & Excretion of a Single Oral Dose [14C]AZD0530 in Healthy Male VolunteersCompletedNCT00853983Phase 1
- Randomized Study Comparing the Effect of Dasatinib and Imatinib on Malignant Stem Cells in Chronic Myeloid LeukemiaCompletedNCT00852566Phase 2
- Docetaxel With or Without a Phytochemical in Treating Patients With Breast CancerTerminatedNCT00852332Phase 2
- Ph II Trial of a Novel Anti-angiogenic Agent in Combination With Chemotherapy for the Second-line Treatment of Metastatic Colorectal CancerCompletedNCT00851045Phase 2
- Ph II of a Novel Anti-angiogenic Agent in Combination With Chemotherapy for the Treatment of Non-Small Cell Lung CancerTerminatedNCT00850577Phase 2
- Dasatinib (Sprycel™) in Patients With Newly Diagnosed Core Binding Factor (CBF) Acute Myeloid Leukemia (AML)CompletedNCT00850382Phase 1/2
- Study of the Safety and Tolerability of PCI-32765 in Patients With Recurrent B Cell LymphomaCompletedNCT00849654Phase 1
- Safety and Dosage Study of RAD001 (Everolimus) in Combination With Current Standard of Care to Treat Advanced Solid Tumors.CompletedNCT00849550Phase 1
- A Study to Examine the Effects of Esomeprazole on the Pharmacokinetics of Orally Administered Lapatinib in Subjects With Metastatic ErbB2 Positive Breast CancerCompletedNCT00849329Phase 1
- ATAC - Arimidex, Tamoxifen Alone or in CombinationCompletedNCT00849030Phase 3
- Study of Sorafenib in Patients With Advanced Renal Cell CarcinomaCompletedNCT00848640Phase 2
- Safety of SGI-1776, A PIM Kinase Inhibitor in Refractory Prostate Cancer and Relapsed/Refractory Non Hodgkin's LymphomaTerminatedNCT00848601Phase 1
- Ursodiol for Treating Parenteral Nutrition Associated Cholestasis in NeonatesCompletedNCT00846963Phase 2/3
- Y-90 Alone or With Sorafenib for Pre-Transplant Hepatocellular CarcinomaCompletedNCT00846131Phase 1
- Glivec in Pediatric Chronic Myeloid Leukemia (CML)CompletedNCT00845221Phase 4
- Study of Sorafenib and Gemcitabine in Advanced Hepatocellular Carcinoma (HCC)Status unknownNCT00844688Phase 2
- Sorafenib Tosylate in Treating Patients With Liver Cancer Who Have Undergone a Liver TransplantCompletedNCT00844168Phase 1
- Efficacy of Oral AB1010 in Adult Patients With Severe Persistent Corticosteroid Dependent AsthmaCompletedNCT00842270Phase 2
- A Study Of Selective Cyclin Dependent Kinase Inhibitor P1446A-05 In Subjects With Advanced Refractory MalignanciesCompletedNCT00840190Phase 1