Protease Inhibitors: all 1,856 studies that test it

Page 18 of 19. Open to participants first (69), then studies with results posted, then the rest; newest registration first within each.

• Comparing the Safety, Effectiveness, and Tolerability of Three Anti-HIV Drug Regimens for Treatment-Naive PatientsCompletedNCT00050895Phase 3
• Influence of the MDR1 Genotype on Blood Levels of Indinavir and Saquinavir in Healthy VolunteersCompletedNCT00050180Phase 4
• Comparing Standard-Dose Versus Adjusted-Dose Lopinavir/Ritonavir Therapy in HIV-Infected Persons With Drug ResistanceCompletedNCT00046033Phase 2
• Study of Lopinavir, Ritonavir, Tenofovir and Emtricitabine in HIV-Infected Antiretroviral Naïve SubjectsCompletedNCT00043966Phase 3
• Lopinavir/Ritonavir in Combination With Saquinavir Mesylate or Lamivudine/Zidovudine to Explore Metabolic Toxicities in Antiretroviral HIV-Infected SubjectsCompletedNCT00043953Phase 2
• Study to Explore Safety And Tolerability of Fosamprenavir With or Without Ritonavir in Combination With TRIZIVIR or COMBIVIRCompletedNCT00043888Phase 3
• BMS-275291 in Treating Patients With Prostate Cancer That Has Not Responded to Hormone TherapyCompletedNCT00040755Phase 2
• Study of Gemcitabine Chemoradiation and TNP-470 Patients Locally Advanced, Nonmetastatic Adenocarcinoma of PancreasTerminatedNCT00038701Phase 2
• A Study of Two Different Doses of ABT-378/Ritonavir in HIV-Infected Patients Who Have Taken Protease Inhibitors and Non-Nucleoside Reverse Transcriptase InhibitorsCompletedNCT00038636Phase 3
• Amprenavir/Ritonavir, Saquinavir/Ritonavir or Efavirenz in HIV-Infected Subjects Following Failure With Kaletra (ABT-378/Ritonavir) as Their First Protease Inhibitor Based HAARTCompletedNCT00038532Phase 2
• Amprenavir/Ritonavir or Saquinavir/Ritonavir in HIV-Infected Subjects Following Failure With Kaletra as Their Second Protease InhibitorCompletedNCT00038519Phase 2/3
• Safety and Effectiveness of Lopinavir/Ritonavir in HIV Infected InfantsCompletedNCT00038480Phase 1
• Effectiveness of ABT-378/Ritonavir Plus Lamivudine Plus Efavirenz Plus Tenofovir DF in HIV-Infected PatientsCompletedNCT00038220Phase 2
• A Randomized, Placebo-Controlled Trial of BMS-275291 Given Daily for 12 Months to Women With Stage 1c-IIIA Breast Cancer Receiving Adjuvant Chemotherapy and/or Hormonal TherapyTerminatedNCT00036621Phase 2
• A Phase II Study to Determine the Efficacy and Safety of Sivelestat in Subjects With Acute Lung InjuryCompletedNCT00036062Phase 1/2
• S-3304 in Treating Patients With Advanced Solid TumorsCompletedNCT00033566Phase 1
• A Phase 1 Study of S-3304 in Patients With Solid TumorsCompletedNCT00033215Phase 1
• Dual Versus Triple Protease Inhibitor Combinations, Including Ritonavir, in HIV Infected PeopleCompletedNCT00028366Not applicable
• Atazanavir Versus Lopinavir/Ritonavir (LPV/RTV) in Patients Who Have Not Had Success With Protease Inhibitor-Containing HAART Regimen(s)CompletedNCT00028301Phase 3
• A Comparison of Atazanavir and Nelfinavir, Each in Combination With 2 NRTIs, in Patients Who Have Failed Treatments Without a Protease InhibitorTerminatedNCT00028067Phase 3
• Using Drug Levels and Drug Resistance Testing to Select Effective Anti-HIV Drug Combinations in Patients With Drug-resistant HIVCompletedNCT00027339Phase 2
• Comparison of Two Dosing Regimens of GW433908/Ritonavir Versus Lopinavir/Ritonavir for 48 Weeks in HIV Patients Who Have Taken Protease Inhibitors and Experienced Virological FailureStatus unknownNCT00025727Phase 3
• BMS-275291 in Treating Patients With HIV-Related Kaposi's SarcomaCompletedNCT00024024Phase 1/2
• TBTC Study 23B:Intensive PK of the Nelfinavir Rifabutin Interaction in Patients With HIV-TBCompletedNCT00023400Phase 4
• Effect of a Change in HIV Therapy on Liver Steatosis, Inflammation, and FibrosisWithdrawnNCT00023218Not applicable
• AE-941 in Treating Patients With Relapsed or Refractory Multiple MyelomaCompletedNCT00022282Phase 2
• A Phase II Trial of COL-3 in Patients With HIV Related Kaposi's SarcomaTerminatedNCT00020683Phase 2
• The Effect of Efavirenz and Nelfinavir on the Blood Levels of Certain Lipid-Lowering DrugsCompletedNCT00017758Phase 1
• Ritonavir and Indinavir in Children Failing Other Anti-HIV TreatmentCompletedNCT00012519Phase 1/2
• Comparison of GW433908/Ritonavir to Nelfinavir When Used With Abacavir and Lamivudine in Patients That Have Not Taken Antiretroviral DrugsStatus unknownNCT00009061Phase 3
• Comparison of GW433908 and Nelfinavir in HIV Patients Who Have Not Had Antiretroviral TherapyStatus unknownNCT00008554Phase 3
• Four-Drug Combination Therapy With Zidovudine, Lamivudine, 1592U89 (Abacavir), and 141W94 (Amprenavir) in HIV-Infected PatientsCompletedNCT00006617Not applicable
• Ritonavir and Agenerase Treatment for Patients Who Have Failed Previous Anti-HIV TreatmentStatus unknownNCT00006591Not applicable
• Effectiveness of Adding Interleukin-2 to Anti-HIV Drugs in Patients Recently Infected With HIVCompletedNCT00006441Not applicable
• Differences Between Women and Men Taking a Combination of Indinavir, Ritonavir, Enteric-Coated Didanosine, and Stavudine Who Previously Took Anti-HIV DrugsStatus unknownNCT00006397Phase 3
• A Study to Evaluate the Use of a Protease Inhibitor and of Interleukin-2 (IL-2) in the Treatment of Early HIV InfectionCompletedNCT00006154Phase 3
• AE-941 in Treating Patients With Metastatic Kidney CancerCompletedNCT00005995Phase 3
• Combination Chemotherapy Plus Radiation Therapy With or Without AE-941 in Treating Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed By SurgeryCompletedNCT00005838Phase 3
• Drug Interactions of Amprenavir and Efavirenz, in Combination With a Second Protease Inhibitor, in HIV-Negative VolunteersCompletedNCT00005762Not applicable
• The Safety and Effectiveness of Indinavir Plus Ritonavir Plus Two NRTIs in HIV-Infected Patients Who Need Early Intervention TreatmentStatus unknownNCT00005118Phase 2
• A Comparison of Three Anti-HIV Drug Combinations in HIV-Infected PatientsCompletedNCT00005106Phase 4
• Treatment With Nelfinavir or Efavirenz of HIV-Infected Patients Who Have Never Received Anti-HIV DrugsStatus unknownNCT00005000Phase 4
• Effectiveness of a New Anti-HIV Drug (AG1549) Plus Viracept (Nelfinavir) Plus Combivir (Zidovudine/Lamivudine) in HIV-Infected PatientsSuspendedNCT00004999Phase 2
• Combination Treatment Using Capravirine (AG1549), Nelfinavir, and Two Nucleoside Reverse Transcriptase Inhibitors in HIV Patients Who Failed Initial Combination TherapyCompletedNCT00004985Phase 2
• A Phase III Study Comparing Two Different Anti-HIV Drug Combinations in HIV-Positive Patients Without Previous Anti-HIV Drug TherapyCompletedNCT00004583Phase 3
• ABT-378/Ritonavir and Efavirenz in HIV-Infected Patients Who Have Taken More Than One Protease Inhibitor in the PastCompletedNCT00004582Phase 2
• A Study to Compare Two Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Previously Received Anti-HIV TreatmentCompletedNCT00004581Phase 3
• A Study of ABT-378/Ritonavir Combination in HIV-Infected Patients Who Have Taken Protease InhibitorsCompletedNCT00004580Phase 1
• ABT-378/Ritonavir in Combination With Reverse Transcriptase Inhibitors in Antiretroviral Naïve HIV-Infected SubjectsCompletedNCT00004578Phase 1/2
• Prinomastat Plus Temozolomide Following Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma MultiformeCompletedNCT00004200Phase 2
• Prinomastat and Combination Chemotherapy in Treating Patients With Metastatic or Recurrent Non-small Cell Lung CancerCompletedNCT00004199Phase 3
• COL-3 in Treating Patients With Progressive or Recurrent Brain TumorsCompletedNCT00004147Phase 1/2
• Chemotherapy in Treating Patients With Advanced Solid TumorsCompletedNCT00003721Phase 1
• Marimastat Following Chemotherapy in Treating Patients With Small Cell Lung CancerCompletedNCT00003011Phase 3
• Marimastat or No Further Therapy in Treating Women With Metastatic Breast Cancer That Is Responding or Stable Following ChemotherapyCompletedNCT00003010Phase 3
• Marimastat in Treating Patients With Stage III Non-small Cell Lung CancerCompletedNCT00002911Phase 3
• A Study on the Safety and Effectiveness of L-756423 Plus Indinavir in HIV-Positive Patients Who Have Previously Taken IndinavirCompletedNCT00002452Phase 2
• Safety and Effectiveness of Giving Indinavir, Ritonavir, Stavudine, and Lamivudine to HIV-Infected Patients Who Have Never Received Anti-HIV DrugsStatus unknownNCT00002451Phase 2
• A Study to Compare the Effects of Two Anti-HIV Drug Combinations on the Immune Systems of HIV-Infected PatientsCompletedNCT00002448Phase 3
• A Study to Compare Two Anti-HIV Drug CombinationsCompletedNCT00002447Phase 3
• A Study to Compare the Effectiveness of Two Anti-HIV Drug CombinationsCompletedNCT00002430Not applicable
• The Safety and Effectiveness of Saquinavir Soft Gelatin Capsules Combined With Other Anti-HIV DrugsCompletedNCT00002425Phase 4
• A Study to Compare the Safety and Effectiveness of Indinavir Combined With Stavudine and LamivudineSuspendedNCT00002424Phase 2
• A Study to Compare Two Anti-HIV Drug Combinations That Include Amprenavir in HIV-Infected Patients Who Have Failed Anti-HIV Drug Combinations That Did Not Include AmprenavirCompletedNCT00002423Phase 2
• Safety and Effectiveness of Giving Adefovir Dipivoxil Plus Abacavir Plus Efavirenz Plus Amprenavir to HIV-Infected Patients Who Have Failed to Respond to Previous Protease Inhibitor TreatmentCompletedNCT00002419Phase 2
• A Study of Amprenavir in Patients With Protease Inhibitor-Related ComplicationsCompletedNCT00002417Not applicable
• A Study of Three Different Anti-HIV Drug Combinations in HIV-Infected PatientsCompletedNCT00002410Phase 3
• A Comparison of Two Dose Levels of Indinavir Combined With Two Nucleoside Analogue Reverse Transcriptase Inhibitors (NRTIs) in HIV-Infected PatientsCompletedNCT00002406Phase 3
• A Study of Amprenavir in HIV-Infected PatientsCompletedNCT00002405Not applicable
• A Study of Delavirdine Used Together With Other Anti-HIV Drugs in HIV-Infected PatientsCompletedNCT00002401Not applicable
• A Study of Two Anti-HIV Drug Combinations in HIV-Infected PatientsCompletedNCT00002400Not applicable
• A Study of Saquinavir Soft Gel Capsules (SGC) Used in Combination With Two Other Anti-HIV Drugs in Patients With HIV-Associated Kidney DiseaseCompletedNCT00002397Phase 3
• A Study of Indinavir Taken With or Without DMP 266CompletedNCT00002393Phase 3
• The Safety and Effectiveness of Indinavir Sulfate Plus EfavirenzCompletedNCT00002387Not applicable
• Effect of Indinavir Plus Two Other Anti-HIV Drugs on Blood Clotting in HIV-Positive Males With HemophiliaCompletedNCT00002386Phase 4
• A Comparison of Saquinavir Hard- and Soft-Gelatin Capsules in HIV-Infected PatientsCompletedNCT00002383Phase 1
• A Study of Saquinavir Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected PatientsCompletedNCT00002382Phase 3
• The Safety and Effectiveness of Nevirapine Plus Nelfinavir in HIV-1 Infected Patients Who Have Taken StavudineCompletedNCT00002381Phase 1
• The Safety and Effectiveness of Two Forms of Saquinavir Combined With Other Anti-HIV Drugs in HIV-Infected Infants and ChildrenCompletedNCT00002380Phase 1
• The Safety and Effectiveness of Adefovir Dipivoxil Plus Indinavir Combined With Zidovudine or Lamivudine or Stavudine in HIV-Infected Patients Who Have Not Taken Anti-HIV DrugsCompletedNCT00002379Phase 2
• A Comparison of Three Anti-HIV Drug Combinations Containing Saquinavir Soft Gelatin Capsules Used in HIV-1 Infected PatientsCompletedNCT00002378Phase 3
• Safety and Effectiveness of Giving Indinavir and Nelfinavir to HIV-Infected PatientsCompletedNCT00002375Not applicable
• A Study of Saquinavir Soft Gelatin Capsules Combined With Other Anti-HIV Drugs in HIV-1 Infected PatientsCompletedNCT00002374Phase 3
• A Study of Saquinavir Soft Gelatin Capsules Plus Zidovudine Plus Lamivudine in the Treatment of HIV-1 Infected Patients Who Have Never Taken Anti-HIV DrugsCompletedNCT00002367Phase 3
• The Safety and Effectiveness of Ritonavir in the Treatment of HIV-Related Kaposi's SarcomaCompletedNCT00002366Phase 2
• Safety and Effectiveness of an Anti-HIV Drug Combination in HIV-Positive Patients Who Have Failed Previous Treatment With Protease InhibitorsCompletedNCT00002361Phase 2
• A Study of Indinavir Sulfate Given Together With Stavudine to HIV-Positive PatientsCompletedNCT00002354Not applicable
• A Study of L-735,524 in HIV-Positive Children and AdolescentsCompletedNCT00002351Phase 1
• A Study of Zidovudine (AZT) Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Patients With Little or No Previous TreatmentCompletedNCT00002334Phase 3
• A Study of Saquinavir and Zalcitabine, Used Alone and Together, in the Treatment of Advanced HIV Infection in Patients Who Stopped Taking or Who Cannot Take ZidovudineCompletedNCT00002333Phase 2
• A Study of the Effects of Amprenavir, a Protease Inhibitor, on Carbohydrate and Fat Metabolism in HIV-Infected PatientsCompletedNCT00002245Phase 3
• Safety and Effectiveness of an Anti-HIV Drug Combination Taken Twice DailyStatus unknownNCT00002241Phase 2
• A Study to Compare Three Doses of T-20 When Given in Combination With Abacavir, Amprenavir, Ritonavir, and Efavirenz to HIV-Infected AdultsCompletedNCT00002239Phase 2
• A Study to Find the Best Dosing Schedule for Delavirdine, Zidovudine, and Indinavir in HIV-Positive PatientsCompletedNCT00002236Not applicable
• A Study on the Safety and Effectiveness of Twice-Daily Nelfinavir Plus Twice-Daily Indinavir Plus Efavirenz in HIV-Positive Patients Who Have Never Taken Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) or Protease InhibitorsCompletedNCT00002235Phase 2
• A Study of a Combination of Four Drugs in Patients With Recent HIV InfectionCompletedNCT00002233Phase 2
• Safety and Effectiveness of Adding Saquinavir (FORTOVASE) in Soft Gel Capsule Form to an Anti-HIV Drug Combination in HIV-Infected PatientsCompletedNCT00002229Phase 4
• A Study of Ritonavir/Indinavir Combination in HIV-Infected PatientsCompletedNCT00002223Not applicable
• Indinavir Plus Efavirenz Plus Adefovir Dipivoxil in HIV-Infected Patients Who Have Not Had Success With NelfinavirCompletedNCT00002220Phase 3
• Safety and Effectiveness of Adding Adefovir Dipivoxil and Nelfinavir to the Anti-HIV Therapy of HIV-Infected ChildrenStatus unknownNCT00002219Phase 2

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