Neratinib: all 67 studies that test it
Page 1 of 1. Open to participants first (15), then studies with results posted, then the rest; newest registration first within each.
- Neu Direction: Testing the Efficacy of Adding HER Inhibition to Standard of Care in Metastatic MLH1-low Endocrine-resistant ER+/HER2- Breast CancerNot yet recruitingNCT07729046Phase 2
- T-DXd With or Without Neratinib for HER2 Positive Breast Cancer With Brain MetastasisRecruitingNCT07152782Phase 2
- Using Tumor Models to Determine TreatmentsRecruitingNCT06813079Phase 2
- Neratinib Tablets Monotherapy for Advanced Solid Tumors With HER2 MutationsNot yet recruitingNCT06519110Phase 2
- Neratinib Tablets in the Treatment of Advanced NSCLC With Rare EGFR MutationsNot yet recruitingNCT06029816Phase 2
- Neratinib in Combination With Ruxolitinib in Patients With mTNBCRecruitingNCT06008275Early Phase 1
- Genetically-informed Therapy for ER+ Breast Cancer Post-CDK4/6 InhibitorRecruitingNCT05933395Phase 2
- Adjuvant Trastuzumab Plus Neratinib in Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer After Neoadjuvant Trastuzumab Plus PertuzumabRecruitingNCT05760612Phase 3
- Personalized Medicine for Advanced Biliary Cancer PatientsRecruitingNCT05615818Phase 3
- Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening TrialRecruitingNCT05564377Phase 2
- Kadcyla And Neratinib for Interception of HER2+ Breast Cancer With Molecular Residual DiseaseRecruitingNCT05388149Phase 2
- Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 GeneRecruitingNCT05372614Phase 1
- Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast CancersRecruitingNCT04886531Phase 2
- Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)RecruitingNCT04374305Phase 2
- INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)RecruitingNCT02977780Phase 2
- Neratinib and Capmatinib Combination (Phase Ib/II) in Metastatic Breast Cancer and Inflammatory Breast Cancer Patients With Abnormal HER-family and c-Met Pathway Activity as Measured by the CELsignia Signaling Analysis TestTerminatedNCT05243641Phase 1/2Results posted
- A Study to Characterize Colon Pathology in Patients With HER2 Amplified Breast Cancer Treated With NeratinibCompletedNCT04366713Phase 2Results posted
- Neratinib in Treating Older Patients With Stage IV HER2-Positive Breast CancerCompletedNCT02673398Phase 2Results posted
- A Dose-Escalation Study Evaluating the Combination of Trastuzumab Emtansine (T-DM1) With Neratinib in Women With Metastatic HER2-Positive Breast CancerCompletedNCT02236000Phase 1/2Results posted
- A Study of Neratinib Plus Capecitabine Versus Lapatinib Plus Capecitabine in Patients With HER2+ Metastatic Breast Cancer Who Have Received Two or More Prior HER2 Directed Regimens in the Metastatic SettingCompletedNCT01808573Phase 3Results posted
- HKI-272 for HER2-Positive Breast Cancer and Brain MetastasesCompletedNCT01494662Phase 2Results posted
- A Study Of Neratinib (HKI-272) And Capecitabine In Japanese With Solid TumorCompletedNCT01128842Phase 1Results posted
- Temsirolimus Plus Neratinib for Patients With Metastatic HER2-Amplified or Triple Negative Breast CancerCompletedNCT01111825Phase 1/2Results posted
- Phase II Randomized Trial Evaluating Neoadjuvant Therapy With Neratinib and/or Trastuzumab Followed by Postoperative Trastuzumab in Women With Locally Advanced HER2-positive Breast CancerCompletedNCT01008150Phase 2Results posted
- Study Evaluating Neratinib In Combination With Vinorelbine In Subjects With Advanced Or Metastatic Solid TumorsCompletedNCT00958724Phase 1Results posted
- Study Evaluating Neratinib Plus Paclitaxel VS Trastuzumab Plus Paclitaxel In ErbB-2 Positive Advanced Breast CancerCompletedNCT00915018Phase 2Results posted
- Study Evaluating The Effects Of Neratinib After Adjuvant Trastuzumab In Women With Early Stage Breast CancerCompletedNCT00878709Phase 3Results posted
- Study Evaluating Neratinib In Combination With Temsirolimus In Subjects With Solid TumorsCompletedNCT00838539Phase 1Results posted
- Study Evaluating Neratinib Versus Lapatinib Plus Capecitabine For ErbB2 Positive Advanced Breast CancerCompletedNCT00777101Phase 2Results posted
- Study Evaluating Safety And Tolerability, Solid TumorCompletedNCT00768469Phase 1Results posted
- Study Evaluating The Combination Of Neratinib And Capecitabine In Solid Tumors And Breast CancerCompletedNCT00741260Phase 1/2Results posted
- Study Evaluating Neratinib (HKI-272) In Combination With Vinorelbine In Subjects With Solid Tumors And Metastatic Breast CancerCompletedNCT00706030Phase 1/2Results posted
- A Phase 1/2 Study of HKI-272 (Neratinib) in Combination With Paclitaxel (Taxol) in Subjects With Solid Tumors and Breast CancerCompletedNCT00445458Phase 1/2Results posted
- A Phase 1/2 Study Of HKI-272 (Neratinib) in Combination With Trastuzumab (Herceptin) In Subjects With Advanced Breast CancerCompletedNCT00398567Phase 1/2Results posted
- A Study Of The Safety And Tolerability Of HKI-272 Administered Orally To Japanese Subjects With Advanced Solid TumorsCompletedNCT00397046Phase 1Results posted
- Study Evaluating HKI-272 (Neratinib) In Subjects With Advanced Breast CancerCompletedNCT00300781Phase 2Results posted
- Study Evaluating the Safety Of HKI-272 (Neratinib) In Subjects With Advanced Non-Small Cell Lung CancerCompletedNCT00266877Phase 2Results posted
- Study Evaluating HKI-272 in TumorsCompletedNCT00146172Phase 1Results posted
- Neratinib In Combination With Chemotherapy/Trastuzumab/Pembrolizumab In HER2 Gastroesophageal CancerActive, not recruitingNCT06109467Phase 2
- Neratinib and Trastuzumab Biosimilar in Patients with HER2 Mutated Advanced Solid CancersCompletedNCT06083662Phase 2
- Neratinib Dose Escalation Regimen for HER2 Positive Early Breast CancerStatus unknownNCT05154396Phase 2
- Fulvestrant + Neratinib In Breast CancerWithdrawnNCT04901299Phase 2
- Evaluation of Neratinib for Treatment and Prevention of Subsequent CNS Event(s) in Patients With Brain Metastasis of Advanced HER2 Positive Breast CancerWithdrawnNCT04856475Phase 2
- Neratinib in Patients With Metastatic Castration-Resistant Prostate CancerWithdrawnNCT04781374Phase 2
- Niraparib and Neratinib in Advanced Solid Tumors With Expansion Cohort in Advanced Ovarian CancerActive, not recruitingNCT04502602Phase 1
- Targeting EGFR/ERBB2 With Neratinib in Hormone Receptor (HR)-Positive/HER2-negative HER2-enriched Advanced/Metastatic Breast CancerTerminatedNCT04460430Phase 2
- Neratinib + Valproate in Advanced Solid Tumors, w/Expansion Cohort in Ras-Mutated CaSuspendedNCT03919292Phase 1/2
- Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME TrialTerminatedNCT03878524Phase 1
- Evaluating the Efficacy of Neratinib on Live Cell HER2 Signaling Transduction Analysis Positive Triple Negative BreastActive, not recruitingNCT03812393Phase 2
- Capecitabine 7/7 Schedule With Neratinib in Patients With Metastatic HER2-Positive Breast CancerCompletedNCT03377387Phase 1/2
- The UK Plasma Based Molecular Profiling of Advanced Breast Cancer to Inform Therapeutic CHoices (plasmaMATCH) TrialStatus unknownNCT03182634Phase 2
- Safety and Dose Finding Study of Neratinib in Children and Young Adults With Cancer That Has Returned or Not Responded to TreatmentActive, not recruitingNCT02932280Phase 1/2
- Phase1 of Neratinib+Trastuzumab, Pertuzumab, Paclitaxel in Patients With Advanced Solid Tumors/HER2+TerminatedNCT02593708Phase 1
- Open-label PK Study to Evaluate Lansoprazole and Neratinib in Healthy SubjectsCompletedNCT02334501Phase 1
- Safety and Efficacy Study of Neratinib and Cetuximab to Treat Patients With Quadruple Wild-Type Metastatic Colorectal CancerWithdrawnNCT01960023Phase 1/2
- Combination of Weekly Paclitaxel With Neratinib and Trastuzumab in Women With Metastatic HER2-positive Breast CancerCompletedNCT01423123Phase 1
- Study Evaluating The Effect Of A High-Fat Meal On The Pharmacokinetics Of NeratinibWithdrawnNCT00932464Phase 1
- Study Evaluating The Potential Effect Of Rifampin On The Pharmacokinetics Of NeratinibCompletedNCT00864487Phase 1
- Study Evaluating The Potential Effect Of Multiple Doses Of Neratinib On The Pharmacokinetics Of A Single Dose Of DigoxinCompletedNCT00860223Phase 1
- Study Evaluating TwoTablet Formulations of Neratinib (HKI-272)CompletedNCT00814060Phase 1
- Study Evaluating The PK And Safety Of Neratinib In Healthy Subjects And Subjects With Chronic Liver DiseaseCompletedNCT00781430Phase 1
- Study Evaluating The Tolerability Of Multiple Doses Of HKI-272CompletedNCT00757809Phase 1
- Study to Examine the Effect of HKI-272 on Rhythms of the Heart (Cardiac Repolarization)CompletedNCT00708903Phase 1
- Study Evaluating Oral Administrations of HKI-272 in Healthy Male SubjectsCompletedNCT00550212Phase 1
- Study Comparing 2 New Formulations of HKI-272 in Healthy Adult SubjectsCompletedNCT00498745Phase 1
- HKI-272 Ketoconazole Drug Interaction StudyCompletedNCT00380328Phase 1
- Study Evaluating HKI-272 Administered to Healthy SubjectsCompletedNCT00366600Phase 1