Muscarinic Antagonists: all 1,032 studies that test it

Page 8 of 11. Open to participants first (107), then studies with results posted, then the rest; newest registration first within each.

• Pharmacokinetics of TD-4208 in Patients With Moderate Hepatic ImpairmentCompletedNCT02581592Phase 1
• Pharmacokinetics of TD-4208 in Patients With Severe Renal ImpairmentCompletedNCT02578082Phase 1
• Spasmolytic in Upper Gastrointestinal EndoscopyCompletedNCT02576340Phase 4
• Ultibro® Versus Spiriva® Alone to Reduce Exertional Dyspnea in Patients With Moderate to Severe COPDCompletedNCT02567214Phase 4
• Hyoscine ButylBromide for Intrapartum AnalgesiaStatus unknownNCT02557087Phase 2
• Exhaled NO Based Treatment of Chronic Obstructive Pulmonary Disease (COPD), ICS/LABA Versus LAMAStatus unknownNCT02546349Phase 4
• Comparisons of Inhaled LAMA or LAMA+LABA or ICS+LABA for COPD With BronchiectasisStatus unknownNCT02546297Phase 4
• The Effects of RPL554 on Top of Standard COPD Reliever MedicationsCompletedNCT02542254Phase 2
• Comparison of 24 Hour Bronchodilator Efficacy of Tiotropium 18 mcg Delivered Via DISCAIR Versus SPIRIVA 18 µg Delivered Via HANDIHALER® in Patients With Moderate to Severe COPDCompletedNCT02541006Phase 4
• Analgesic Efficacy of Intravenous Hyoscine-N-Butylbromide (HNB) in Abdominal Colic Associated With Acute GastroenteritisStatus unknownNCT02508142Phase 4
• The PK Study of the JLP-1207 and Solifenacin/Tamsulosin in Healthy Male Volunteers.CompletedNCT02494349Phase 1
• Prospective Trial Comparing Oxybutynin and Tamsulosin for Stent Pain in the Pediatric PopulationWithdrawnNCT02483793Not applicable
• Intra-Venous Acetaminophen and Muscle Relaxants After Total KneeCompletedNCT02449369Phase 4
• Anticholinergic Premedication Induced Fever in Pediatric Ambulatory Anesthesia With KetamineCompletedNCT02430272Not applicable
• Sugammadex and Cognitive FunctionCompletedNCT02419352Not applicable
• Anesthetics in Rhytidoplasty - A Comparison StudyCompletedNCT02410460Not applicable
• Fesoterodine on Urgency Episodes in Parkinson's Disease PopulationTerminatedNCT02385500Phase 4
• Study of Glycopyrrolate for Moderate-to-severe Sialorrhea in Parkinson's DiseaseStatus unknownNCT02382198Phase 2
• "Low Dose Sugammadex Combined With Neostigmine and Glycopyrrolate Versus Full Dose Sugammadex for Reversal of Rocuronium-induced Neuromuscular Blockade: a Cost Saving Strategy"CompletedNCT02375217Phase 4
• Pharmacovigilance in Gerontopsychiatric PatientsTerminatedNCT02374567Phase 3
• Transdermal Administration of a Prokinetic Agent for Bowel Evacuation in Persons With SCICompletedNCT02370862Early Phase 1
• Use of Prokinetics During Inpatient Bowel Care for SCI PatientsStatus unknownNCT02370433Phase 1
• Fesoterodine and Oxybutynin XL for Overactive Bladder Syndrome in ChildrenCompletedNCT02327936Phase 3
• Ventilation-drive Coupling to Evaluate The Efficacy of Inhaled Bronchodilators in Patients With COPDCompletedNCT02296047Not applicable
• The Use of EEG in Alzheimer's Disease, With and Without Scopolamine - A Pilot StudyCompletedNCT02273895Not applicable
• Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of BEA 2180 BR in Healthy Male SubjectsCompletedNCT02263976Phase 1
• Comparison Between Desmopressin and Fesoterodine for Treatment of Night Time Voiding in Women Aged 65 and OlderTerminatedNCT02262936Phase 2/3
• Pharmacokinetics, Safety and Tolerability of Rising Doses of Buscopan® in Healthy Male VolunteersCompletedNCT02261077Phase 1
• Study to Investigate Safety and Tolerability of BI 1744 CL in Free Dose Combination With Tiotropium Bromide Both Administered by Respimat® in Healthy Male VolunteersCompletedNCT02259946Phase 1
• Relative Bioavailability of Tiotropium and Salmeterol After Inhalation of a Fixed Combined Dose Compared to Monocomponents in Healthy Male VolunteersCompletedNCT02254174Phase 1
• Study to Evaluate Efficacy and Safety of Oral Doses of Hyoscine Butylbromide for the Treatment of Occasional Abdominal Pain, Cramping, and DiscomfortCompletedNCT02242292Phase 2
• Free Combinations of Tiotropium Inhalation Powder Capsule + Salmeterol Metered Dose Inhaler, Tiotropium Inhalation Powder Capsule and Salmeterol Metered Dose Inhaler in Patients With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT02242253Phase 2
• A Study of Fesoterodine and Oxybutynin on Cognitive Function in Mild Cognitive ImpairmentCompletedNCT02240459Phase 2
• Safety Trial of Atrovent® in Pediatric Patients With Rhinorrhea Associated With a Common Cold or AllergyCompletedNCT02238210Phase 4
• Study to Assess the Efficacy of Ipratropium Bromide Associated With High Dose Salbutamol by Repeated Nebulisation Versus Repeat Nebulisation of Salbutamol Alone, in Acute Asthmatic Attacks in Young ChildrenTerminatedNCT02235428Phase 4
• Effect of Glycopyrrolate and Atropine on Catheter-Related Bladder DiscomfortStatus unknownNCT02228473Not applicable
• Intraocular Pressure Changes Associated With Tracheal Extubation: Comparison of Sugammadex With Conventional Reversal of Neuromuscular BlockadeCompletedNCT02215382Phase 4
• Helium-3 MRI Imaging Study in COPDCompletedNCT02207452Phase 1
• Efficacy and Safety of Glycopyrrolate Bromide of COPD PatientsCompletedNCT02189577Phase 2
• 0.6 vs. 1.2 mg Atropine Together With Neostigmine 2.5 mg on Heart Rate in Patient Receiving Muscle RelaxantCompletedNCT02186132Phase 4
• Ipratropium or Salbutamol Sulphate Alone or Combination Therapy Salbutamol and Ipratropium in Patients With COPDCompletedNCT02182856Phase 4
• Combivent vs. Salbutamol in Patients With Metacholine Induced BronchospasmCompletedNCT02182713Phase 4
• Efficacy and Safety of Combivent® Aerosol and Spacer, in Adult Patients With Moderate to Severe Asthma CrisisTerminatedNCT02182700Phase 3
• Acute Effect of Aclidinium on Hyperinflation and Ventilation Inhomogeneity in Severe COPD PatientsCompletedNCT02181023Phase 4
• Clinical Trial to Investigate the Pharmacokinetic Drug Interaction Between Solifenacin and TamsulosinCompletedNCT02180997Phase 1
• A New More Efficient Cycloplegia SchemeStatus unknownNCT02177539Phase 4
• Dose Tolerance Study After Ocular Administration of Tiotropium in Healthy Male VolunteersCompletedNCT02177305Phase 1
• Ipratropium Bromide/Salbutamol Delivered by the Respimat® Inhaler Compared to Ipratropium Bromide Respimat®, COMBIVENT® Inhalation Aerosol and Placebo in Adults With Chronic Obstructive Pulmonary DiseaseCompletedNCT02177253Phase 3
• Pharmacodynamic and Pharmacokinetic Dose Ranging Study of Tiotropium Bromide Administered Via Respimat Device in Patients With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT02175342Phase 2
• Tiotropium Inhalation Capsules and Salmeterol Inhalation Aerosol on Muscular Efficiency and Resting Energy Expenditure (REE) in Patients With Stable Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT02172794Phase 3
• Tiotropium in Combination With Concomitant Cimetidine or Ranitidine in Healthy Male and Female SubjectsCompletedNCT02172417Phase 1
• Multiple Dose Comparison of Tiotropium Inhalation Capsules, Salmeterol Inhalation Aerosol and Placebo in Patients With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT02172287Phase 3
• Study to Evaluate the Effect of Solifenacin and Mirabegron on the Tamsulosin Hydrochloride (HCl) Concentrations in Blood in Healthy Male SubjectsCompletedNCT02169713Phase 1
• Efficacy of Darifenacin and Physiotherapy for the Treatment of Overactive Bladder in WomenCompletedNCT02143570Phase 3
• Low Concentration Atropine for Myopia Progression in School ChildrenCompletedNCT02130167Not applicable
• Study of Efficacy and Safety of NVA237 in Patients With Poorly Controlled AsthmaWithdrawnNCT02127697Phase 3
• Study to Evaluate the Effect of Solifenacin and Mirabegron on the Digoxin Concentrations in Blood in Healthy SubjectsCompletedNCT02127034Phase 1
• Pharmacokinetics of CHF 5993 pMDI With and Without Spacer in COPD PatientsCompletedNCT02119234Phase 1
• Role of Hyoscine Bromide in Latent and Active LaborSuspendedNCT02103166Phase 4
• Evaluate the Efficacy of Oxybutynin Chloride in Patients With Primary HyperhidrosisWithdrawnNCT02099695Phase 3
• Safety Study of Hyoscine N Butyl Bromide in Active Management of LaborCompletedNCT02098889Phase 4
• The Efficacy of Solifenacin Succinate as Adjuvant Therapy for Urinary Tract Infection in FemalesStatus unknownNCT02094703Phase 4
• StahistRx Phase 2, Five-arm, Parallel Group, Active vs Active, Double-blind StudyStatus unknownNCT02082054Phase 2
• A Study to Investigate the Pharmacokinetics, Safety and Tolerability of CHF 5993 pMDI in Subjects With Renal Impairment.CompletedNCT02040597Phase 1
• Evaluation of Long-Acting Muscarinic Antagonists in COPDCompletedNCT02039050Phase 4
• Ultra-long Acting Bronchodilator Therapy in AsthmaticsCompletedNCT02039011Phase 4
• A Study to Compare How Much Solifenacin Succinate and Mirabegron Reach the Blood When Administered Together as Fixed-dose Combination Tablets and With Single Individual Tablets of the Same Medications at Three Dose LevelsCompletedNCT02010944Phase 1
• Post-marketing Study to Evaluate the Effect of Mirabegron on the Plasma Concentration of TolterodineCompletedNCT01964183Phase 4
• A Study to Compare the Amount of Drug in the Blood After a Single Tablet EC905 Containing Solifenacin and Tamsulosin is Taken by Healthy Males Compared to Separate Tablets of Solifenacin and TamsulosinCompletedNCT01953887Phase 1
• The Role of Cholinergic Signaling for Mediating the Effects of GIP and/or Xenin-25 on Insulin SecretionCompletedNCT01951729Phase 1
• Female Patients With Signs of uRgE and Stress Urinary Incontinence Study of Propiverine HydrochlorideCompletedNCT01942681Not applicable
• Characterization of Exposure From Topical Administration of [14C] Umeclidinium to Axilla or Palm of Healthy Male SubjectsCompletedNCT01934153Phase 1
• Validation of Instruments for Pragmatic Clinical Trials for Overactive BladderCompletedNCT01925456Phase 1
• Generalization of Extinction LearningCompletedNCT01900301Phase 1
• Efficacy of a Combined Surgical and Pharmacological Therapy to Treat Mixed Urinary Incontinence.CompletedNCT01899794Phase 4
• Comparison of Tamsulosin and Solifenacin in Treatment of Ureteral Stent SymptomsCompletedNCT01880619Phase 4
• Comparisons of 3-month Versus 6-month Solifenacin Treatment for Female OAB PatientsStatus unknownNCT01876186Phase 4
• Atropine-effect During Propofol/Remifentanil InductionCompletedNCT01871922Not applicable
• Treatment of Hyperhidrosis With OxybutyninCompletedNCT01855256Phase 3
• Hyoscine Butyl Bromide for Management of Prolonged LaborStatus unknownNCT01854073Phase 3
• Efficacy of NVA237 (50 μg o.d) Using Tiotropium (5μg μg o.d) as Active Control in COPD Patients.WithdrawnNCT01837927Phase 3
• Flexibly adding-on Second Antimuscarinic Agent to the First Antimuscarinics for Refractory Overactive Bladder SyndromeCompletedNCT01824420Phase 4
• Safety and Efficacy of NVA237 as an add-on to Fixed Dose Combination LABA/ICSWithdrawnNCT01757015Phase 3
• Post Marketing Study to Evaluate the Efficacy and Safety of Solifenacin in Patients With OAB (Overactive Bladder) After TURP (Trans-urethral Resection of Prostate) or PVP (Photoselective Vaporization of Prostate)CompletedNCT01747577Phase 4
• Dose Ranging Study of Glycopyrronium Bromide in Patients With Moderate or Severe Chronic Obstructive Pulmonary DiseaseCompletedNCT01703624Phase 2
• Indacaterol Versus Tiotropium on Dynamic Hyperinflation in COPDCompletedNCT01693003Phase 4
• A Study to Assess the Systemic Exposure, Systemic Pharmacodynamics and Safety and Tolerability of FluticasoneFuroate, Umeclidinium and Vilanterol in Healthy SubjectsCompletedNCT01691547Phase 1
• A Study of Effects of Fesoterodine in Men at High Risk for Overactive Bladder/Detrusor Overactivity Post Robotic-Assisted Lap. ProstatectomyCompletedNCT01661166Phase 4
• Effect of Hyoscine and Promethazine on Labor PainCompletedNCT01644838Phase 2/3
• A Randomized, Placebo-Controlled Study to Assess the Efficacy of Propantheline for the Treatment of Overactive BladderStatus unknownNCT01640002Phase 1
• Drotaverine to Shorten the Length of LaborCompletedNCT01639027Phase 2/3
• Efficacy and Safety of 400 μg Twice Daily of Aclidinium Bromide vs. Placebo When Administered to Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT01636401Phase 3
• Post-treatment Novmalized Urodynamiz Findings as the Golden Standard of Objective Cure for Female Overactive Bladder Patients Receiving Antimuscarinic DrugStatus unknownNCT01627145Not applicable
• Ketamine and Scopolamine Infusions for Treatment-resistant Major Depressive DisorderWithdrawnNCT01613820Not applicable
• Comparing the Pharmacokinetics, Safety and Tolerability of NVA237 in Renal ImpairmentCompletedNCT01613690Phase 1
• Atropine Versus no Atropine for Neonatal Rapid Sequence IntubationStatus unknownNCT01595399Phase 4
• Solifenacin Succinate Versus Fesoterodine A Comparison Trial for Urgency SymptomsStatus unknownNCT01595152Not applicable
• Excessive Sweating Caused by Antidepressants: Measurement and Treatment With Glycopyrrolate (AIDES-G)TerminatedNCT01588717Phase 1
• Comparison of Efficacy and Safety Between Imidafenacin and Fesoterodine in Patients With Overactive BladderCompletedNCT01578304Phase 4
• A Study to Assess the Effects of GSK573719/VI Combination and GSK573719 Monotherapy in Subjects With Moderate Hepatic Impairment and Matched Healthy VolunteersCompletedNCT01577680Phase 1

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