LGK974 clinical trials
Also written WNT974.
- studies test it
- 3
- open now
- 0
- in phase 3
- 0
- first study started
- 2011
How each study uses LGK974 is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
Studies by the year they started
2 studies that test it; most in 2011 (1)
| Year | Studies |
|---|---|
| 2011 | 1 |
| 2014 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 2 · Other 1
Novartis Pharmaceuticals (1) · Array BioPharma (1) · University of Michigan Rogel Cancer Center (1)
Often tested with
Tested in the same studies.
Studies
Open first, then newest update. How each study uses LGK974 is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 3
- A Study of LGK974 in Patients With Malignancies Dependent on Wnt LigandsCompletedPhase 1Novartis PharmaceuticalsNCT01351103Written as LGK974
- Study of WNT974 in Combination With LGX818 and Cetuximab in Patients With BRAF-mutant Metastatic Colorectal Cancer (mCRC) and Wnt Pathway MutationsCompletedPhase 1/2Array BioPharmaNCT02278133Written as WNT974
- A Phase II Trial Evaluating WNT974 in Patients With Metastatic Head and Neck Squamous Cell CarcinomaWithdrawnPhase 2University of Michigan Rogel Cancer CenterNCT02649530Written as WNT974
Codes
What other systems call LGK974 · ClinicalTrials.gg INT006433
- MeSH (NLM) C586458LGK974Confirmed ClinicalTrials.gov, NLM
- UNII (FDA) U27F40013QWNT-974Confirmed FDA, NLM
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C586458 | LGK974 | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | U27F40013Q | WNT-974 | Confirmed FDA, NLM |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.