Leukotriene Antagonists: all 255 studies that test it

Page 1 of 3. Open to participants first (17), then studies with results posted, then the rest; newest registration first within each.

• Evaluating The Role Of Montelukast In Management Of Acute BronchiolitisRecruitingNCT07770464Phase 2
• MIRACLE-T2D Montelukast Intervention for Renal, Cardiovascular and Eye Health in Type 2 DiabetesNot yet recruitingNCT07685886Phase 4
• Effect of Montelukast on Inflammatory Markers and Cardiac Injury in Patients With Acute Myocardial InfarctionRecruitingNCT07537868Phase 2
• Comparison of Antihistamine and Antileukotriene Add-On Therapy to Intranasal Corticosteroid in Allergic RhinitisNot yet recruitingNCT07532993Phase 4
• SMART 2D: Study of Montelukast's Effects on Renal and Cardiovascular Health in Adolescents and Young Adults With Type 2 DiabetesRecruitingNCT07409714Early Phase 1
• Efficacy of Montelukast on STEMl PatientsRecruitingNCT07320625Phase 3
• PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary DysplasiaRecruitingNCT07101640Phase 1/2
• Lipid Mediators & Cancer: Montelukast, SPM, and AlmondsNot yet recruitingNCT06887673Early Phase 1
• Efficacy of Montelukast in Preventing Transaminase Elevation in Adult Dengue PatientsRecruitingNCT06747130Phase 2/3
• Serum Intercellular Adhesion Molecule -1 in Acne Vulgaris Patients : Effect of MontelukastNot yet recruitingNCT06340984Phase 3
• Crossover Study of Zafirlukast in Preventing Allergen-induced Signs and Symptoms in Response to Cat Dander ChallengeNot yet recruitingNCT06069063Phase 2
• Clinical Evaluation of Montelukast in Veterans With Gulf War IllnessRecruitingNCT05992311Phase 1
• Effect of Montelukast on Kidney and Vascular Function in Type 1 DiabetesRecruitingNCT05498116Phase 4
• Air Pollution (PM2.5) on Accelerated Atherosclerosis: A Montelukast Interventional Study in Modernizing ChinaNot yet recruitingNCT04762472Phase 4
• MOntelukast as a Potential CHondroprotective Treatment Following Anterior Cruciate Ligament Reconstruction (MOCHA Trial)RecruitingNCT04572256Early Phase 1
• SMILES: Study of Montelukast in Sickle Cell DiseaseRecruitingNCT04351698Phase 2/3
• Effect of Some Drugs on Rheumatoid Arithritis ActivityRecruitingNCT03770923Phase 3
• ACTIV-6: COVID-19 Study of Repurposed Medications - Arm F (Montelukast)CompletedNCT05894577Phase 3Results posted
• Premedication to Reduce Amivantamab Associated Infusion Related ReactionsActive, not recruitingNCT05663866Phase 2Results posted
• Targeting Leukotrienes in Kidney DiseaseTerminatedNCT05362474Phase 3Results posted
• ACTIV-6: COVID-19 Study of Repurposed MedicationsCompletedNCT04885530Phase 3Results posted
• Evaluation of Pharmacokinetic Interaction Between GSK3640254 and Caffeine, Metoprolol, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin in Healthy AdultsCompletedNCT04425902Phase 1Results posted
• Zafirlukast in Treatment of Marker Relapsed Ovarian CancerCompletedNCT04339140Phase 2Results posted
• Efficacy of Montelukast in Reducing the Incidence and Severity of Monoclonal Antibodies Associated Infusion ReactionsCompletedNCT04198623Phase 2Results posted
• Montelukast Therapy on Alzheimer's DiseaseCompletedNCT03991988Phase 2Results posted
• Breast Capsular Contracture Following Post-Mastectomy Reconstruction in Women Treated With the Leukotriene Inhibitor Zafirlukast: A Phase II TrialTerminatedNCT02950480Phase 2Results posted
• Does Montelukast Decrease Post Adenotonsillectomy Pain in ChildrenCompletedNCT02793375Phase 3Results posted
• Efficacy of Co-administration of Bilastine and Montelukast in Patients With SARC and AsthmaCompletedNCT02761252Phase 4Results posted
• Study of Montelukast on Gastrointestinal Tolerability in Patients With Relapsing Forms of Multiple Sclerosis Receiving TecfideraCompletedNCT02410278Phase 4Results posted
• CYP2B6 Genetics and Drug Interactions in Healthy VolunteersCompletedNCT02401256Phase 4Results posted
• Aspirin and Zileuton and Biomarker Expression in Nasal Tissue of Current SmokersCompletedNCT02348203Phase 2Results posted
• Drug-Drug Interaction Study: ASP2151 and MontelukastCompletedNCT02321748Phase 1Results posted
• Study of the Efficacy and Safety of MK-0476 in Japanese Pediatric Participants With Seasonal Allergic Rhinitis (MK-0476-519)CompletedNCT01857063Phase 3Results posted
• Single Dose Bronchodilatory Study in AsthmaCompletedNCT01805687Phase 4Results posted
• Roflumilast Plus Montelukast in Adults With Severe AsthmaCompletedNCT01765192Phase 2Results posted
• A Study to Evaluate the Safety of Combination Montelukast/Loratadine in Mexican Participants With Allergic Rhinitis (MK-0476A-484)CompletedNCT01673620Phase 3Results posted
• A Dose-Ranging Study of MK-1029 in Adults With Persistent Asthma (MK-1029-012)TerminatedNCT01656395Phase 2Results posted
• Study to Evaluate the Effectiveness and Safety of MK-1029 in the Treatment of Persistent Asthma That is Not Controlled With Montelukast (ML) in Adults (MK-1029-011)CompletedNCT01624974Phase 2Results posted
• Individualized Therapy For Asthma in ToddlersCompletedNCT01606306Phase 3Results posted
• A Trial of Montelukast for Maintenance Therapy of Eosinophilic Esophagitis in ChildrenTerminatedNCT01458418Not applicableResults posted
• The Effect of Montelukast on Asthma Control in Overweight/Obese Atopic AsthmaticsCompletedNCT01329939Not applicableResults posted
• Targeted Therapy of Bronchiolitis Obliterans SyndromeCompletedNCT01307462Phase 2Results posted
• Montelukast and Inhaled Nasal Steroid Tx in Adult Obstructive Sleep Apnea (OSA)CompletedNCT01089647Phase 3Results posted
• Early Airway Response to Allergen in Asthmatics (MK-0000-176)CompletedNCT01061333Phase 1Results posted
• Effect of Montelukast Therapy in Obstructive Sleep Apnea(OSA) ChildrenTerminatedNCT01027806Phase 4Results posted
• Moderate to Persistent Asthma in the Obese SubjectTerminatedNCT01016847Phase 4Results posted
• Montelukast in Patients With Seasonal Allergic Rhinitis - Spring 2000 Study (MK-0476A-162)(COMPLETED)CompletedNCT00979901Phase 3Results posted
• Montelukast in Perennial Allergic Rhinitis - 2001-2002 Study (0476-246)CompletedNCT00974571Phase 3Results posted
• Montelukast in Seasonal Allergic Rhinitis - Spring 2001 Study (0476-235)CompletedNCT00972738Phase 3Results posted
• Chronic Asthma Study in 2- to 5-Year-Old Patients (MK0476-072 )CompletedNCT00968201Phase 3Results posted
• A Study Comparing Montelukast With Placebo in Children With Seasonal Allergic Rhinitis (0476-219)(COMPLETED)CompletedNCT00968149Phase 3Results posted
• Montelukast in Seasonal Allergic Rhinitis - Fall 1999 Study (0476A-117)CompletedNCT00963599Phase 3Results posted
• Montelukast in Seasonal Allergic Rhinitis: Fall 2001 Study (0476-240)CompletedNCT00963469Phase 3Results posted
• A Study Investigating the Effect of Montelukast in Patients With Seasonal Allergic Rhinitis (MK-0476-192)(COMPLETED)CompletedNCT00960141Phase 3Results posted
• Montelukast in Pediatric Patients Aged 6 to 24 Months With Asthma--Safety Study (0476-176)CompletedNCT00943683Not applicableResults posted
• Extended Safety Study of Montelukast in Infants and Young Children With Chronic Asthma (0476-232)CompletedNCT00943397Phase 3Results posted
• The Clinical Effect of MK0476 With Concomitant Administration of and Removal of Inhaled Beclomethasone in Asthmatic Patients (0476-029)CompletedNCT00911547Phase 3Results posted
• Trial of Montelukast for Treatment of Acute BronchiolitisCompletedNCT00863317Not applicableResults posted
• Pediatric ACTION3 (Identify, Treat, Control): Effectiveness of Adding Montelukast in Pediatric Subjects With Uncontrolled Asthma (0476-385)CompletedNCT00832455Phase 4Results posted
• The Safety and Effectiveness of MK0476 (Montelukast) in Patients With Chronic Asthma (0476-388)CompletedNCT00739297Phase 1Results posted
• The Effects of Montelukast on Smokers With AsthmaCompletedNCT00712335Phase 4Results posted
• Montelukast to Treat Bronchiolitis ObliteransCompletedNCT00656058Phase 2Results posted
• A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Inhaled Montelukast (MK-0476) in Participants With Mild or Moderate Asthma (MK-0476-380 AM3)(COMPLETED)CompletedNCT00636207Phase 1Results posted
• The Role of Montelukast in Rhinitis and SleepCompletedNCT00590772Phase 4Results posted
• Efficacy Study of Montelukast in Atopic Dermatitis Induced by Food AllergensCompletedNCT00557284Phase 4Results posted
• Singulair(R) In Asthma And Allergic Rhinitis (0476-383)CompletedNCT00545844Phase 4Results posted
• The Effect of Montelukast on Difficulty in Breathing After Exercise in Pediatric Patients (MK0476-377)(COMPLETED)CompletedNCT00534976Phase 4Results posted
• Zileuton to Treat Adults With Chronic Obstructive Pulmonary Disease (The LEUKO Study)TerminatedNCT00493974Phase 3Results posted
• Pilot Study of a Multi-Drug Regimen for Severe Pulmonary Fibrosis in Hermansky-Pudlak SyndromeTerminatedNCT00467831Phase 1/2Results posted
• Montelukast Back to School Asthma Study (0476-340)CompletedNCT00461032Phase 3Results posted
• Montelukast in Mild Asthmatic Children With Allergic Rhinitis (0476-367)CompletedNCT00442559Phase 4Results posted
• Study of MK-0476 in Adult Patients With Acute Asthma (0476-334)CompletedNCT00442338Phase 3Results posted
• Childhood Asthma Research and Education (CARE) Network Trial - Best Add-On Therapy Giving Effective Response (BADGER)CompletedNCT00395304Phase 3Results posted
• Study of the Arachidonate 5-Lipoxygenase Enzyme in Affecting the Risk for Coronary Heart DiseaseCompletedNCT00379808Not applicableResults posted
• Effect of Montelukast on Experimentally-Induced RV16 Infection in AsthmaCompletedNCT00359073Not applicableResults posted
• Intermittent and Daily Dosing for Episodic (Periodic) Asthma (0476-302)(COMPLETED)CompletedNCT00337675Phase 3Results posted
• Study Of Allergic Rhinitis In Patients Who Also Have AsthmaCompletedNCT00296491Phase 4Results posted
• Compare the Efficacy of Levocetirizine and Montelukast to Placebo in Reducing Seasonal Allergic Rhinitis (SAR) Symptoms in Ragweed Sensitive SubjectsCompletedNCT00295022Phase 4Results posted
• Montelukast in Pediatric Allergic Asthma (0476-336)(COMPLETED)CompletedNCT00289874Phase 3Results posted
• Montelukast Asthmatic Smoker Study (0476-332)(COMPLETED)CompletedNCT00284856Phase 3Results posted
• Montelukast Compared With Placebo and Salmeterol in Exercise-Induced Bronchoconstriction (0476-316)CompletedNCT00245570Phase 3Results posted
• MK0476 Study in Adult Patients With Acute Asthma (0476-322)CompletedNCT00229970Phase 3Results posted
• Evaluate the Potential of Montelukast to Prevent Nasal Symptomatology During ColdsCompletedNCT00189475Phase 4Results posted
• A Pilot Study to Evaluate the Efficacy of Montelukast in the Treatment of Acute Otitis Media (AOM) in ChildrenCompletedNCT00189462Phase 4Results posted
• Two Investigational Drugs in the Prevention of Airway Constriction Brought on by Exercise in Participants With Asthma (0476-911)CompletedNCT00127166Phase 3Results posted
• The Addition of Montelukast to Fluticasone in the Treatment of Perennial Allergic RhinitisTerminatedNCT00119015Phase 4Results posted
• A Study of an Intravenous Drug in Pediatric Patients With Acute Asthma (0476-301)CompletedNCT00117338Phase 3Results posted
• Montelukast for Early Life WheezingCompletedNCT00115297Phase 2/3Results posted
• Montelukast in Exercise-Induced Bronchospasm - 2003 (0476-270)CompletedNCT00092131Phase 3Results posted
• The Clinical Effects of Montelukast in Patients With Perennial Allergic Rhinitis (0476-265)CompletedNCT00092118Phase 3Results posted
• Montelukast in Exercise-Induced Bronchospasm - 2004 (0476-275)CompletedNCT00090142Phase 3Results posted
• A Pilot Study of Mirabegron and Montelukast in Cirrhotic PatientsCompletedNCT07533565Phase 4
• Montelukast in Parkinson DiseaseCompletedNCT06113640Phase 2/3
• Effect of Montelukast on Doxorubicin Induced Cardiotoxicity in Breast CancerCompletedNCT05959889Not applicable
• Treating Exacerbations of Asthma With Oral Montelukast in ChildrenCompletedNCT05819541Phase 2
• Medical vs Surgical Treatment in OSA Among ChildrenStatus unknownNCT05651750Phase 4
• Montelukast Use in Rheumatoid ArthritisCompletedNCT05447520Phase 2
• Value of Montelukast as a Potential Treatment of Post COVID-19 Persistent CoughCompletedNCT05447039Not applicable
• Impact Of Montelukast On Allergic Rhinitis And Its Inflammatory MakersStatus unknownNCT05381207Early Phase 1
• Effect of Montelukast Versus Co Enzyme in SepsisCompletedNCT05293132Phase 2/3

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