Ifebemtinib clinical trials
Also written IN10018 and BI 853520.
How each study uses ifebemtinib is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
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Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
Studies by the year they started
16 studies that test it; most in 2025 (4)
| Year | Studies |
|---|---|
| 2011 | 1 |
| 2013 | 1 |
| 2020 | 3 |
| 2022 | 3 |
| 2023 | 2 |
| 2025 | 4 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 15 · Other 1
InxMed (Shanghai) Co., Ltd. (10) · Boehringer Ingelheim (2) · InventisBio Co., Ltd (1) · Shanghai Jeyou Pharmaceutical Co., Ltd. (1) · Hangzhou Hanx Biopharmaceuticals, Ltd. (1) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (1)
Often tested with
Tested in the same studies.
Garsorasib (2) · Sosimerasib (1) · RNK08954 (1) · Anti-PD-1/CD47 Fusion Protein HX009 (1)
Related medicines
As reviewed, each with the page that says it.
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Reaching primary completion within a year · 1
Studies that test ifebemtinib.
- Mar 2027IN10018 in Combination With Pegylated Liposomal Doxorubicin (PLD) vs. Placebo in Combination With PLD for the Treatment of Platinum-resistant Recurrent Ovarian CancerPhase 2 · InxMed (Shanghai) Co., Ltd.
Studies
Open first, then newest update. How each study uses ifebemtinib is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 16
- IN10018 in Combination With RNK08954 for the Treatment of KRASG12D Mutation-Positive Locally Advanced or Metastatic Solid TumorsRecruitingPhase 1/2InxMed (Shanghai) Co., Ltd.NCT07441174Written as IN10018 in combination with RNK08954
- A Phase 3 Study of IN10018 in Combination With D-1553 Versus Standard Therapy for First Line Non-squamous Non-small Cell Lung Cancer With KRAS G12C MutationRecruitingPhase 3InxMed (Shanghai) Co., Ltd.NCT07174908Written as IN10018 in combination with D-1553
- A Phase 3 Study of Sosimerasib in Combination With IN10018 Versus Standard Therapy for First Line Non-squamous Non-small Cell Lung Cancer With KRAS G12C MutationNot yet recruitingPhase 3Shanghai Jeyou Pharmaceutical Co., Ltd.NCT07833202Written as Sosimerasib in combination with IN10018
- HX009+ IN10018 With or Without Standard Chemotherapy for Advanced Solid TumoursRecruitingPhase 1/2Hangzhou Hanx Biopharmaceuticals, Ltd.NCT06708663Written as HX009+IN10018
- IN10018 With Nab-Paclitaxel and Cadonilimab for Metastatic or Recurrent Gastric-Type Cervical Adenocarcinoma: Phase 2 TrialRecruitingPhase 2Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyNCT06654011Written as IN10018
- IN10018 Combination Therapy in Advanced EGFR Mutation-positive NSCLCActive, not recruitingPhase 1/2InxMed (Shanghai) Co., Ltd.NCT05994131Written as IN10018
- IN10018+ Standard Chemotherapy (+KN046) in Subjects With Advanced Pancreatic CancerActive, not recruitingPhase 1/2InxMed (Shanghai) Co., Ltd.NCT05827796Written as IN10018
- IN10018 Combination Therapy in Treatment-naïve ES-SCLCActive, not recruitingPhase 1/2InxMed (Shanghai) Co., Ltd.NCT06030258Written as IN10018
- IN10018 in Combination With Standard Chemotherapy in High-grade Serous Epithelial Ovarian CancerActive, not recruitingPhase 1/2InxMed (Shanghai) Co., Ltd.NCT05551507Written as IN10018 in combination with PLD
- IN10018 in Combination With Pegylated Liposomal Doxorubicin (PLD) vs. Placebo in Combination With PLD for the Treatment of Platinum-resistant Recurrent Ovarian CancerActive, not recruitingPhase 2InxMed (Shanghai) Co., Ltd.NCT06014528Written as IN10018
- Study to Evaluate D-1553 in Combination With IN10018 in Subjects With Solid TumorsActive, not recruitingPhase 1/2InventisBio Co., LtdNCT05379946Written as IN10018
- IN10018 Combination Therapy in Previously-treated Solid TumorsWithdrawnPhase 1/2InxMed (Shanghai) Co., Ltd.NCT05982522Written as IN10018
- IN10018 Monotherapy and Combination Therapy for Metastatic MelanomaCompletedPhase 1InxMed (Shanghai) Co., Ltd.NCT04109456Written as IN10018
- IN10018 Monotherapy or in Combination With Docetaxel in Gastric or GEJ AdenocarcinomaCompletedPhase 1InxMed (Shanghai) Co., Ltd.NCT05327231Written as IN10018
- A Study of BI 853520 in Patients With Various Types of Advanced or Metastatic CancerCompletedPhase 1Boehringer IngelheimNCT01335269Written as BI 853520
- A Study of BI 853520 in Japanese and Taiwanese Patients With Various Types of Advanced or Metastatic CancerCompletedPhase 1Boehringer IngelheimNCT01905111Written as BI 853520
Given beside what is tested · 3 — ifebemtinib is usual care or a partner of the new treatment
- IN10018 in Combination With Dalpiciclib for Progressive MeningiomasRecruitingPhase 1Capital Medical UniversityNCT07652762Written as Ifebemtinib
- A Phase Ib Study of JMKX001899 in Combination With Other Therapies in Advanced NSCLC Harboring KRAS G12C MutationRecruitingPhase 1JemincareNCT06946927Written as IN10018
- a Study to Evaluate the Safety and Efficacy of D-1553 Combined With IN10018 in KRAS G12C Mutant Solid TumorsActive, not recruitingPhase 1/2InxMed (Shanghai) Co., Ltd.NCT06166836Written as IN10018(Ifebemtinib)
Codes
What other systems call ifebemtinib · ClinicalTrials.gg INT016181
- UNII (FDA) C57O858DKUIFEBEMTINIBOne source FDA
- NCI Thesaurus C166122IfebemtinibOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| UNII (FDA) | C57O858DKU | IFEBEMTINIB | One source FDA |
| NCI Thesaurus | C166122 | Ifebemtinib | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.