Drug

EC145 clinical trials

Also written Vintafolide, EC145 and MK-8109.

studies test it: 10
open now: 0
in phase 3: 1
first study started: 2006

How each study uses EC145 is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study

Approvals

The first approval found in each region, with its record

United States: Not in FDA's approval records
European Union: Not in EMA's list of EU-wide authorisations

From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out

How studies write it

Studies that test it under each name

Development codes

EC145: 5
MK-8109: 2

Other names

Vintafolide: 6
Vintafolide 2.5 mg: 1

Studies by the year they started

10 studies that test it; most in 2007 (2)

Studies that test EC145, by start year
Year	Studies
2006	1
2007	2
2008	1
2009	1
2011	2
2012	1
2014	2

By phase

A phase 1/2 study counts in both.

Phase 1: 3
Phase 2: 6
Phase 3: 1

What it is tested for

Each study’s main condition, where its own words name it, so a study counts once.

Ovarian Neoplasms: 3
Neoplasms: 2
Carcinoma, Non-Small-Cell Lung: 1
Breast Neoplasms: 1

Who runs them

Industry 10 · Other 0

Endocyte (10)

Often tested with

Tested in the same studies.

Paclitaxel (1)

Related medicines

As reviewed, each with the page that says it.

One of Antimitotic agents source

Studies

Open first, then newest update. How each study uses EC145 is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.