Daridorexant: all 46 studies that test it

Page 1 of 1. Open to participants first (12), then studies with results posted, then the rest; newest registration first within each.

• A Trial to See if Daridorexant Can Help Adults and Elderly People With Insomnia Sleep Better During the Night and Function Better During the DayNot yet recruitingNCT07843329Phase 3
• Daridorexant for Sleep Disturbance in Adults With Liver CirrhosisNot yet recruitingNCT07830303Phase 4
• Evaluating the Efficacy and Safety of Daridorexant Transition From BZRAs in Insomnia Patients（EASY-TIP）Not yet recruitingNCT07733414Phase 4
• Daridorexant for People With Insomnia and Alcohol Use Disorder StudyNot yet recruitingNCT07701928Phase 2
• Efficacy and Safety of Daridorexant in Patients With Major Depressive Disorder and InsomniaNot yet recruitingNCT07555743Phase 4
• Daridorexant for Alcohol Use DisorderNot yet recruitingNCT07532252Phase 2
• Impact of Daridorexant on Sleep, Daytime Alertness, and SmokingNot yet recruitingNCT07328594Phase 4
• Dual Orexin Antagonism and Emotion and Affective Processing StudyRecruitingNCT07267559Phase 4
• Daridorexant to Prevent Post-cardiotomy DeliriumRecruitingNCT07217912Phase 2
• Daridorexant for Alzheimer Disease PreventionRecruitingNCT07213349Phase 2
• Comparing Digital Therapy, Trazodone, and Daridorexant for Menopause-Related Insomnia SymptomsRecruitingNCT07136415Phase 4
• Daridorexant to Treat Insomnia in Patients With Mild Cognitive Impairment and Mild to Moderate Alzheimer DiseaseRecruitingNCT05924425Phase 4
• Daridorexant to Prevent Delirium After Heart SurgeryCompletedNCT06630390Phase 2Results posted
• A Study to Find Out if Daridorexant is Safe and Efficacious in Patients With Insomnia and Comorbid NocturiaCompletedNCT05597020Phase 4Results posted
• Study to Assess the Long Term Safety and Tolerability of ACT-541468 (Daridorexant) in Adult and Elderly Subjects Suffering From Difficulties to SleepCompletedNCT03679884Phase 3Results posted
• Study to Assess the Efficacy and Safety of ACT-541468 (Daridorexant) in Adult and Elderly Subjects Suffering From Difficulties to SleepCompletedNCT03575104Phase 3Results posted
• Study to Assess the Efficacy and Safety of ACT-541468 (Daridorexant) in Adult and Elderly Subjects With Insomnia DisorderCompletedNCT03545191Phase 3Results posted
• Efficacy and Safety of ACT-541468 in Elderly Subjects With Insomnia DisorderCompletedNCT02841709Phase 2Results posted
• Efficacy and Safety of ACT-541468 in Adult Subjects With Insomnia DisorderCompletedNCT02839200Phase 2Results posted
• A Study to Evaluate the Efficacy and Safety of Daridorexant in Participants With Insomnia DisorderCompletedNCT07028697Phase 3
• Investigate the PK, Safety, and Tolerability After Single and Multiple Dose Daridorexant in Chinese Healthy SubjectsCompletedNCT06326723Phase 1
• A Study of Daridorexant in Chinese Patients With Insomnia DisorderCompletedNCT06010693Phase 3
• A Phase 1 Trial to Investigate the Biological Equivalence of 5 × 10 mg Tablets and 2 × 25 mg Tablets of Daridorexant in Healthy Male and Female Japanese ParticipantsCompletedNCT05877222Phase 1
• A Study of the Effect of Daridorexant on Nighttime Body Posture, the Noise Level Required to Wake up, and the Ability to Remember Words Previously PresentedCompletedNCT05702177Phase 1
• A Study to Measure Daridorexant in Breast Milk of Healthy Lactating WomenCompletedNCT05632393Phase 1
• A Study to Examine the Effect of Daridorexant on the Way the Body Absorbs, Distributes, and Gets Rid of Midazolam and Warfarin in Healthy Male SubjectsCompletedNCT05480488Phase 1
• A Study to Examine the Effect of Daridorexant on the Way the Body Absorbs, Distributes, and Gets Rid of Dabigatran and Rosuvastatin in Healthy Male SubjectsCompletedNCT05480475Phase 1
• A Study to Investigate the Effects of Daridorexant on Nighttime Breathing in Patients With Shallow or Paused Breath During SleepCompletedNCT05458193Phase 1
• Dose-finding Study Assessing the Efficacy, Safety, and Pharmacokinetics of Daridorexant in Subjects Aged 10 to < 18 Years With Insomnia DisorderCompletedNCT05423717Phase 2
• A Study in Healthy Male Subjects to Investigate the Effect of Famotidine and Efavirenz on the Way the Body Takes up, Distributes, and Gets Rid of Daridorexant.CompletedNCT04390334Phase 1
• A Study to Assess the Effect of Single Doses of Daridorexant on Electrocardiogram Parameters in Healthy SubjectsCompletedNCT04250506Phase 1
• Study of the Way the Body Takes up, Distributes, and Gets Rid of ACT-541468 in Subjects With Abnormal Kidney Function Compared to Healthy SubjectsCompletedNCT04024332Phase 1
• A Clinical Study to Examine the Drug-drug Interactions Between ACT-541468 and Citalopram in Healthy Male and Female SubjectsCompletedNCT03907215Phase 1
• A Clinical Study to Assess Next-day Driving Performance Following Administration of ACT-541468 in Middle-aged and Elderly SubjectsCompletedNCT03892902Phase 1
• A Clinical Study to Investigate the Food Effect on the Pharmacokinetics of ACT-541468 in Healthy Male SubjectsCompletedNCT03799978Phase 1
• A Study to Investigate the Effects of ACT-541468 on Nighttime Respiratory Function in Patients With Mild to Moderate Obstructive Sleep ApneaCompletedNCT03765294Phase 1
• A Study to Evaluate the Pharmacokinetics of ACT-541468 in Subjects With Mild, Moderate, and Severe Hepatic ImpairmentCompletedNCT03713242Phase 1
• Study to Evaluate the Abuse Potential of ACT-541468 in Healthy Recreational Drug UsersCompletedNCT03657355Phase 1
• A Study to Evaluate the Effects of ACT-541468 on Respiration in Patients With Moderate Chronic Obstructive Pulmonary DiseaseCompletedNCT03646864Phase 1
• A Study to Investigate the Drug-drug Interactions Between ACT-541468 and Ethanol in Healthy SubjectsCompletedNCT03609775Phase 1
• A Study in Healthy Male Subjects to Investigate Whether Administration of ACT-541468 Can Affect the Fate in the Body (Amount and Time of Presence in the Blood) of RosuvastatinCompletedNCT03339752Phase 1
• A Study of ACT-541468 in Healthy Japanese and Caucasian SubjectsCompletedNCT03101189Phase 1
• A Clinical Study to Investigate the Potential Interactions Between Food and ACT-541468 and Between ACT-541468 and MidazolamCompletedNCT03017495Phase 1
• A Single Ascending Dose Study of ACT-541468 in Healthy Male SubjectsCompletedNCT02919319Phase 1
• A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of ACT-541468 in Healthy Young Adults and Elderly SubjectsCompletedNCT02571855Phase 1
• Pharmacokinetic Interaction Between Diltiazem and ACT-541468 in Healthy SubjectsCompletedNCT02526888Phase 1

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