Daptomycin: all 66 studies that test it
Page 1 of 1. Open to participants first (3), then studies with results posted, then the rest; newest registration first within each.
- Does Staphylococcus Aureus Bacteremia Early Dual Therapy Improve Outcomes?Enrolling by invitationNCT07148960Phase 4
- Daptomycin vs. Vancomycin for the Treatment of Methicillin Resistant S. Aureus BacteremiaRecruitingNCT06637332Phase 4
- Preoperative Daptomycin Prophylaxis in Two-Stage Exchange Arthroplasty: A Prospective, Randomized, Double-Blinded TrialNot yet recruitingNCT06189885Not applicable
- Safety, Efficacy, and Pharmacokinetics (PK) of Daptomycin (MK-3009) in Japanese Pediatric Subjects With Complicated Skin and Soft Tissue Infections (cSSTI) and Bacteremia (MK-3009-029)CompletedNCT03643952Phase 2Results posted
- Safety and Efficacy Study of Daptomycin Compared to Active Comparator in Pediatric Participants With Acute Hematogenous Osteomyelitis (AHO) (MK-3009-006)CompletedNCT01922011Phase 3Results posted
- Safety & Efficacy of Daptomycin Versus Standard of Care (SOC) in 1 - 17 Year Olds With Staphylococcus Aureus Bacteremia (MK-3009-005)CompletedNCT01728376Phase 4Results posted
- Daptomycin Versus Vancomycin in Participants With Skin Infections Due to MRSACompletedNCT01419184Phase 4Results posted
- Vancomycin Versus Daptomycin for the Treatment of Methicillin-resistant Staphylococcus Aureus Bacteremia Due to Isolates With High Vancomycin Minimum Inhibitory Concentrations (MICs)TerminatedNCT01287832Phase 4Results posted
- Daptomycin Versus Placebo in Patients With Neutropenia and FeverTerminatedNCT01216241Phase 3Results posted
- Application of Daptomycin in MRSA Infected Diabetic Foot in Comparison to Vancomycin TreatmentTerminatedNCT01199783Phase 3Results posted
- Study to Compare Efficacy and Safety of Daptomycin in Elderly Patients With Complicated Skin and Soft Tissue InfectionsCompletedNCT01184872Phase 3Results posted
- Study Comparing Cubicin With Vancomycin in Treatment of Participants With Complicated Skin and Skin Structure Infections in a Home Infusion SettingTerminatedNCT01175707Phase 4Results posted
- Study of Daptomycin Safety and Efficacy for Complicated Skin and Skin Structure Infections (cSSSI) and Bacteremia in Renal ImpairmentTerminatedNCT01104662Phase 4Results posted
- Cerebrospinal Fluid Pharmacokinetics of DaptomycinTerminatedNCT01025271Not applicableResults posted
- Study of the Pharmacokinetics of Daptomycin in Children With Renal DiseaseCompletedNCT01012089Not applicableResults posted
- An Open Label Study to Describe the Pharmacokinetics of Daptomycin in InfantsCompletedNCT00942149Phase 1Results posted
- Study to Evaluate Daptomycin Given During Dialysis and After DialysisCompletedNCT00882557Phase 1Results posted
- China Registration Study in Patients With Skin InfectionsCompletedNCT00772447Phase 3Results posted
- A Study of MK-3009 in Japanese Patients With Skin or Blood Stream Infections Caused by Methicillin-resistant Staphylococcus Aureus (MK-3009-002)CompletedNCT00770341Phase 3Results posted
- Safety and Efficacy Study of Daptomycin in Pediatric Participants (1 to 17 Years-old) With Skin and Skin Structure InfectionsCompletedNCT00711802Phase 4Results posted
- Pharmacokinetics of Daptomycin During Cardiopulmonary Bypass SurgeryCompletedNCT00701636Phase 3Results posted
- Phase 2 Study of Safety, Efficacy, and Pharmacokinetics of Higher Doses of Daptomycin and Vancomycin in MRSA BacteremiaTerminatedNCT00695903Phase 2Results posted
- Pharmacokinetics of Daptomycin in Critically Ill Patients Receiving Continuous Venovenous Hemodialysis (CVVHD)CompletedNCT00663403Phase 4Results posted
- Phase 4 Efficacy and Safety Study of Cubicin® With and Without Combination Therapy in S. Aureus Infective Endocarditis (SAIE)TerminatedNCT00638157Phase 4Results posted
- A Pilot Study of Daptomycin for Antimicrobial ProphylaxisTerminatedNCT00572260Phase 4Results posted
- Catheter Related - Gram Positive Bloodstream InfectionsCompletedNCT00467272Phase 2Results posted
- Safety and Efficacy of Daptomycin for the Treatment of Complicated Skin and Skin-structure InfectionsTerminatedNCT00463801Phase 4Results posted
- Efficacy and Safety of Daptomycin Versus Vancomycin or Teicoplanin for Treatment of Complicated Skin and Soft Tissue InfectionsTerminatedNCT00430937Phase 3Results posted
- Study of Daptomycin in Subjects Undergoing Surgery for Osteomyelitis Associated With an Infected Prosthetic Caused by StaphylococciCompletedNCT00428844Phase 2Results posted
- Daptomycin as an Adjuvant Agent in the Treatment of Enterococcal Native Valve Endocarditis.TerminatedNCT00401960Phase 4Results posted
- Daptomycin in Treating Neutropenia and Fever in Patients With CancerCompletedNCT00335478Phase 2Results posted
- Daptomycin for the Treatment of Severe Necrotizing Soft-Tissue InfectionsCompletedNCT00261807Not applicableResults posted
- Subcutaneous Daptomycin in Healthy Volunteers (DAPTOSC)CompletedNCT04434300Phase 1
- Adjunction of Daptomycin for the Treatment of Pneumococcal MeningitisCompletedNCT03480191Phase 2
- Daptomycin as Adjunctive Therapy for Staphylococcus Aureus BacteremiaCompletedNCT02972983Phase 4
- The Pharmacokinetics/Pharmacodynamics of High-dose Daptomycin in Patients With Septic ShockStatus unknownNCT02508350Not applicable
- Evaluation of Single-dose Pharmacokinetics of Intravenous Daptomycin in Patients With Thermal InjuryWithdrawnNCT02241941Phase 4
- Population Pharmacokinetic (PK) Study of Multiple Doses of Cubicin® (Daptomycin) 10 mg/kg in Critical Care Patients Having Bacteremia, Endocarditis or Skin Soft Tissue Infections Due to Gram Positive Bacteria With Various Degrees of Renal FailureCompletedNCT02142075Phase 3
- Influence of Rifampin Co-Administration on the Pharmacokinetic Profile of DaptomycinCompletedNCT02097953Early Phase 1
- Vancomycin Versus Daptomycin for the Treatment of Methicillin Resistant Staphylococcus Aureus (MRSA) BacteremiaTerminatedNCT01975662Phase 2
- Efficacy of Daptomycin Plus Fosfomycin Versus Daptomycin for Treatment of MRSA BacteremiaCompletedNCT01898338Phase 3
- Staphylococcus Aureus Bacteremia Antibiotic Treatment OptionsCompletedNCT01792804Phase 3
- The Effects of Daptomycin and Cytokines Production in Comparison With VancomycinCompletedNCT01626560Phase 4
- Daptomycin in Pediatric Patients With Bacterial MeningitisTerminatedNCT01522105Phase 1
- Daptomycin + Meropenem Versus Ceftazidime in the Treatment of Nosocomial Spontaneous Bacterial PeritonitisTerminatedNCT01455246Phase 2/3
- Daptomycin Pharmacokinetics in Critically Ill Patients Undergoing Continuous Veno-venous Hemodiafiltration, a Dose Finding StudyStatus unknownNCT01212432Phase 2
- Daptomycin Use for Antimicrobial Prophylaxis in Methicillin Resistant Staphylococcus Aureus (MRSA) Colonized Adult Patients Undergoing Primary Elective Hip, Knee, or Shoulder ArthroplastyTerminatedNCT01196169Phase 4
- Daptomycin Pharmacokinetics in Continuous Veno-venous HemodiafiltrationStatus unknownNCT01171547Phase 2
- Daptomycin With Rifampin for Treatment of Staphylococcal Prosthetic Joint InfectionStatus unknownNCT01144000Phase 2
- Outpatient Treatment of Gram Positive Wound Infections in the Diabetic Foot: A Pharmaco-economic Comparison of Daptomycin vs. Vancomycin Based RegimensTerminatedNCT01133600Phase 4
- Daptomycin as Antibiotic Prophylaxis of Sternal Wound InfectionsCompletedNCT01080963Phase 4
- Pharmacokinetics (PK) and Safety Evaluation of Daptomycin in Children Ages 3-24 Months With Proven or Suspected Gram-positive Infections or Peri-Operative Subjects Receiving Prophylactic AntibioticsCompletedNCT01019395Phase 1
- Pharmacokinetic Study of Daptomycin in Healthy Chinese Subjects Living in ChinaCompletedNCT00858325Phase 1
- PK and Safety Evaluation of Daptomycin in Children Ages 2-6 With Proven or Suspected Gram-positive InfectionsCompletedNCT00679835Phase 1
- Cubicin(R) for Complicated Post-surgical Wound InfectionsTerminatedNCT00651131Phase 4
- Study of Cidecin™ (Daptomycin) to Rocephin® (Ceftriaxone) in the Treatment of Moderate to Severe Community-Acquired Acute Bacterial Pneumonia Due to S. PneumoniaeCompletedNCT00540072Phase 3
- Comparative Study of Cidecin™ (Daptomycin) to Rocephin® (Ceftriaxone) in the Treatment of Moderate to Severe Community-Acquired Acute Bacterial PneumoniaCompletedNCT00538694Phase 3
- Daptomycin in the Treatment of Catheter-Related Staphylococcus AureusCompletedNCT00507247Phase 2
- Safety Study to Evaluate Daptomycin in Non-infected Adults Who Are Either on Hemodialysis or Continuous Ambulatory Peritoneal Dialysis (MK-3009-021)CompletedNCT00490737Phase 1
- Phase 2 Safety and Efficacy Study of Daptomycin in Complicated Skin and Skin Structure InfectionsCompletedNCT00426933Phase 2
- Daptomycin or Vancomycin in Treating Bacteria in the Blood in Patients With Neutropenia Caused By ChemotherapyWithdrawnNCT00296049Not applicable
- Study Comparing CUBICIN® (Daptomycin for Injection) With Vancomycin in Cellulitis or ErysipelasCompletedNCT00295178Phase 4
- Study of Single Dose Daptomycin in Pediatric Patients With Gram-positive Infection for Which They Are Receiving Standard AntibioticsCompletedNCT00136292Phase 1
- Daptomycin in the Treatment of Patients With Renal Insufficiency and Complicated Skin and Skin Structure InfectionsTerminatedNCT00102947Phase 4
- Daptomycin in the Treatment of Subjects With Infective Endocarditis or Bacteremia Due to S. AureusCompletedNCT00093067Phase 3
- Daptomycin for the Treatment of Infections Due to Gram-Positive BacteriaTerminatedNCT00055198Phase 3