Drug
Dapivirine clinical trials
Also written TMC-120.
- studies test it
- 30
- open now
- 1
- in phase 3
- 7
- first study started
- 2004
Keep track of what changes. Save the Dapivirine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
Combined with it in one product
Studies by the year they started
29 studies that test it; most in 2005 (4)
| Year | Studies |
|---|---|
| 2004 | 1 |
| 2005 | 4 |
| 2009 | 3 |
| 2010 | 1 |
| 2011 | 4 |
| 2012 | 3 |
| 2013 | 2 |
| 2015 | 2 |
| 2016 | 2 |
| 2017 | 3 |
| 2018 | 1 |
| 2020 | 1 |
| 2022 | 1 |
| 2024 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 21
- Phase 2
- 7
- Phase 3
- 7
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 26 · Other 4
International Partnership for Microbicides, Inc. (26) · National Institute of Allergy and Infectious Diseases (NIAID) (3) · Africa Health Research Institute (1)
Often tested with
Tested in the same studies.
Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination (2) · Miconazole (1) · Cabotegravir (1) · Maraviroc (1)
Studies
Open first, then newest update. How each study uses Dapivirine is read from its arms, and is right about nine times in ten.
Testing it · 30
- Long-Acting HIV Pre-Exposure Prophylaxis Integrated With Sexual and Reproductive Health - cRCTRecruitingPhase 3Africa Health Research InstituteNCT06250504Written as DAPIRING (Dapivirine) 25mg Vaginal Ring
- Randomized, Open Label Safety Trial of Dapivirine Vaginal Ring and Oral TRUVADA® Use in PregnancyCompletedPhase 3National Institute of Allergy and Infectious Diseases (NIAID)NCT03965923Written as Dapivirine (DPV) Vaginal Ring (VR)
- Relative Bioavailability Trial of Dapivirine Ring-004 and Ring-008CompletedPhase 1International Partnership for Microbicides, Inc.NCT05416021Written as dapivirine
- Phase 3 Safety and Effectiveness Trial of Dapivirine Vaginal Ring for Prevention of HIV-1 in WomenCompletedPhase 3International Partnership for Microbicides, Inc.NCT01617096Written as Dapivirine Vaginal Ring
- Safety and Pharmacokinetics of Dapivirine Vaginal Ring in Post-menopausal WomenCompletedPhase 2International Partnership for Microbicides, Inc.NCT02010593Written as Dapivirine Vaginal Ring
- Trial to Assess the Continued Safety of and Adherence to a Vaginal Ring Containing Dapivirine in WomenCompletedPhase 3International Partnership for Microbicides, Inc.NCT02858037Written as Dapivirine Vaginal Ring
- To Assess Continued Safety of and Adherence to the Dapivirine (25 mg) Vaginal Ring-004 in Healthy, HIV-negative WomenCompletedPhase 3International Partnership for Microbicides, Inc.NCT02862171Written as Dapivirine Vaginal Ring-004
- Pharmacokinetic Study of Dapivirine Gel Administered Rectally to HIV-1 Seronegative AdultsCompletedPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT03393468Written as Dapivirine gel
- Safety and Pharmacokinetic Study of Dapivirine Gel (0.05%) Administered Rectally to HIV-1 Seronegative AdultsCompletedPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT03239483Written as Dapivirine gel
- PK and Safety Study of Vaginal Rings Containing Dapivirine and LevonorgestrelCompletedPhase 1International Partnership for Microbicides, Inc.NCT02855346Written as 200 mg of DPV + 320 mg LNG
- Pharmacokinetic Study of the Dapivirine Vaginal Ring in Lactating WomenCompletedPhase 1International Partnership for Microbicides, Inc.NCT02808949Written as Dapivirine
- DDI Potential: Dapivirine Vaginal Ring and Miconazole NitrateCompletedPhase 1International Partnership for Microbicides, Inc.NCT01731574Written as dapivirine
- Safety and Pharmacokinetic Trial in Healthy HIV-Negative Women to Assess the Delivery of Dapivirine From a Vaginal RingCompletedPhase 1International Partnership for Microbicides, Inc.NCT02920827Written as Dapivirine Vaginal Ring
- PK/PD of Single Dose Dapivirine Vaginal FilmCompletedPhase 1International Partnership for Microbicides, Inc.NCT01924091Written as Dapivirine gel
- Assessing the Safety of Dapivirine Gel and Film FormulationsCompletedPhase 1International Partnership for Microbicides, Inc.NCT01548560Written as Dapivirine Vaginal Gel
- Male Tolerance Study of Dapivirine Gel Following Multiple Topical Penile ExposuresCompletedPhase 1International Partnership for Microbicides, Inc.NCT01277640Written as dapivirine
- Reversing the Epidemic in Africa With Choices in HIV Prevention (REACH)WithdrawnPhase 2International Partnership for Microbicides, Inc.NCT03074786Written as Dapivirine
- Dapivirine Gel Rectal Safety and PK StudyWithdrawnPhase 1International Partnership for Microbicides, Inc.NCT03044379Written as Dapivirine gel (0.05%)
- A Safety Study of Dapivirine (TMC120) Vaginal Microbicide Gel in South AfricaWithdrawnPhase 1/2International Partnership for Microbicides, Inc.NCT00304668Written as dapivirine (TMC120) vaginal gel
- A Safety and Efficacy Trial of Dapivirine Vaginal Ring in AfricaWithdrawnPhase 3International Partnership for Microbicides, Inc.NCT01337570Written as Dapivirine
See all 30 studies that test Dapivirine →
As the comparator · 1 — what is tested is compared with Dapivirine
Codes
What other systems call Dapivirine · ClinicalTrials.gg INT004610
- MeSH (NLM) C481671DapivirineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) TCN4MG2VXSDAPIVIRINEConfirmed FDA, NLM, Wikidata
- Wikidata Q27097831dapivirineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C73205DapivirineOne source FDA
- DrugBank DB08639One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C481671 | Dapivirine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | TCN4MG2VXS | DAPIVIRINE | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q27097831 | dapivirine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C73205 | Dapivirine | One source FDA |
| DrugBank | DB08639 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.