Buparlisib: all 81 studies that test it
Page 1 of 1. Open to participants first (0), then studies with results posted, then the rest; newest registration first within each.
- Buparlisib in Patients With Relapsed and Refractory Chronic Lymphocytic LeukemiaCompletedNCT02340780Phase 2Results posted
- Pilot Study of Sonidegib and Buparlisib in Treating Patients With Advanced or Metastatic Basal Cell CarcinomaTerminatedNCT02303041Phase 2Results posted
- Buparlisib (BKM120) In Patients With Recurrent/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Recurrent/Refractory Secondary Central Nervous System Lymphoma (SCNSL)CompletedNCT02301364Phase 2Results posted
- A Study of BKM120 (Buparlisib) in Relapsed or Refractory ThymomasCompletedNCT02220855Phase 2Results posted
- LGX818 and MEK162 in Combination With a Third Agent (BKM120, LEE011, BGJ398 or INC280) in Advanced BRAF MelanomaCompletedNCT02159066Phase 2Results posted
- Palliative Thoracic Radiotherapy Plus BKM120CompletedNCT02128724Phase 1Results posted
- Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and NeckCompletedNCT02113878Phase 1Results posted
- STAR Cape+BKM120 MBC With Brain MetCompletedNCT02000882Phase 2Results posted
- Study of Letrozole With or Without BYL719 or Buparlisib, for the Neoadjuvant Treatment of Postmenopausal WomenCompletedNCT01923168Phase 2Results posted
- Safety and Efficacy of INC280 and Buparlisib (BKM120) in Patients With Recurrent GlioblastomaTerminatedNCT01870726Phase 1/2Results posted
- Study of Efficacy and Safety of Buparlisib (BKM120) Plus Paclitaxel Versus Placebo Plus Paclitaxel in Recurrent or Metastatic Head and Neck Cancer Previously Pre-treated With a Platinum TherapyTerminatedNCT01852292Phase 2Results posted
- BKM120 for Patients With PI3K-activated TumorsCompletedNCT01833169Phase 2Results posted
- PI3K Inhibitor BKM120 and Cetuximab in Treating Patients With Recurrent or Metastatic Head and Neck CancerCompletedNCT01816984Phase 1/2Results posted
- NeoPHOEBE: Neoadjuvant Trastuzumab + BKM120 in Combination With Weekly Paclitaxel in HER2-positive Primary Breast CancerCompletedNCT01816594Phase 2Results posted
- BKM120 For Triple Negative Breast CancerCompletedNCT01790932Phase 2Results posted
- Neoadjuvant BKM120 in High-risk Prostate CancerTerminatedNCT01695473Phase 2Results posted
- Safety and Efficacy of BKM120 in Relapsed and Refractory NHLCompletedNCT01693614Phase 2Results posted
- A Phase III Study of BKM120 With Fulvestrant in Patients With HR+,HER2-, AI Treated, Locally Advanced or Metastatic Breast Cancer Who Progressed on or After mTORiTerminatedNCT01633060Phase 3Results posted
- A Trial of BKM120 (a PI3K Inhibitor) in Patients With Triple Negative Metastatic Breast CancerCompletedNCT01629615Phase 2Results posted
- Phase III Study of BKM120/Placebo With Fulvestrant in Postmenopausal Patients With Hormone Receptor Positive HER2-negative Locally Advanced or Metastatic Breast Cancer Refractory to Aromatase InhibitorCompletedNCT01610284Phase 3Results posted
- A Study of the Experimental Drug BKM120 With Paclitaxel in Patients With HER2 Negative, Locally Advanced or Metastatic Breast Cancer, With or Without PI3K ActivationCompletedNCT01572727Phase 2/3Results posted
- Buparlisib in Metastatic Transitional Cell Carcinoma of the UrotheliumCompletedNCT01551030Phase 2Results posted
- Trial of Erlotinib and BKM120 in Patients With Advanced Non Small Cell Lung Cancer Previously Sensitive to ErlotinibCompletedNCT01487265Phase 2Results posted
- BKM120 in Metastatic Castration-resistant Prostate CancerTerminatedNCT01385293Phase 2Results posted
- Combination of BKM120 and Bevacizumab in Refractory Solid Tumors and Relapsed/Refractory Glioblastoma MultiformeCompletedNCT01349660Phase 1/2Results posted
- Safety and Efficacy of BKM120 in Patients With Metastatic Non-small Cell Lung CancerCompletedNCT01297491Phase 2Results posted
- BKM120 as Second-line Therapy for Advanced Endometrial CancerCompletedNCT01289041Phase 2Results posted
- Double/Triple Combinations of AN2025, AN0025 and Atezolizumab in Advanced Solid TumorsCompletedNCT04975958Phase 1
- A Clinical Trial of Buparlisib and Ibrutinib in LymphomaCompletedNCT02756247Phase 1
- Buparlisib in Melanoma Patients Suffering From Brain Metastases (BUMPER)Status unknownNCT02452294Phase 2
- Study of the Combination of BKM120 and Cisplatin or Carboplatin in Patients With Advanced Solid TumorsCompletedNCT02439489Phase 1
- Trial of BKM120/Tamoxifen-combination in Patients With HR-pos, HER2-neg Breast CancerCompletedNCT02404844Phase 2
- Cisplatin, Etoposide and PI3K Inhibitor BKM120 in Treating Patients With Advanced Solid Tumors or Small Cell Lung CancerCompletedNCT02194049Phase 1
- Dose Escalation Study of LEE011 in Combination With Buparlisib and Letrozole in HR+, HER2-negative Post-menopausal Women With Advanced Breast Cancer.CompletedNCT02154776Phase 1
- Phase I BKM120/Abraxane in Solid Tumors, Expansion Phase Recurrent Endometrial or Ovarian CancerWithdrawnNCT02117817Phase 1
- Study of LEE011 With Fulvestrant and BYL719 or BKM120 in Advanced Breast CancerCompletedNCT02088684Phase 1
- A Phase Ib Dose De-escalation Study With BYL719 in Premenopausal Patients With Locally Advanced or Metastatic Breast CancerCompletedNCT02058381Phase 1
- Study of BKM120 & Rituximab in Patients With Relapsed or Refractory Indolent B-Cell LymphomaCompletedNCT02049541Phase 1
- Pharmacokinetic Study of Buparlisib in Subjects With Renal Impairment.CompletedNCT02048787Phase 1
- Cabazitaxel and BKM120 in Patients With Metastatic Castrate-Resistant Prostate Cancer (mCRPC) Previously Treated With DocetaxelWithdrawnNCT02035124Phase 2
- Buparlisib, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Advanced Solid TumorsWithdrawnNCT01971489Phase 1
- Paclitaxel and BKM120 Before Surgery in Treating Patients With Stage II or III Estrogen Receptor-Positive and HER2-Negative Breast CancerWithdrawnNCT01953445Phase 2
- Phase Ib/II Study of Buparlisib Plus Carboplatin or Lomustine in Patients With Recurrent Glioblastoma MultiformeCompletedNCT01934361Phase 1
- Phase II Study of Buparlisib + Docetaxel in Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) PatientsTerminatedNCT01911325Phase 1
- A Multicenter Phase II Pilot Open LabelStatus unknownNCT01830504Phase 2
- Safety and Efficacy of Buparlisib (BKM120) in Patients With Untreated Squamous Non-small Cell Lung CancerTerminatedNCT01820325Phase 1
- BKM120 in Esophageal Squamous Cell Carcinoma After Failure of First Line ChemotherapyTerminatedNCT01806649Phase 2
- BKM120+Abiraterone Acetate for Metastatic CRPCTerminatedNCT01741753Phase 1
- Activity and Safety Study of BKM120 in Monotherapy in Patient With Metastatic Head and Neck Cancer Recurrent or ProgressiveCompletedNCT01737450Phase 2
- A Study to Find the Maximum Tolerated Dose of the Experimental Combination of the Drugs INC424 and BKM120 in Patients With Primary or Secondary MyelofibrosisTerminatedNCT01730248Phase 1
- Pharmacokinetic Study of BKM120 in Subjects With Hepatic ImpairmentCompletedNCT01727128Phase 1
- PI3K Inhibitor BKM120, Carboplatin, and Pemetrexed Disodium in Treating Patients With Stage IV Non-Small Cell Lung CancerCompletedNCT01723800Phase 1
- Buparlisib in Treating Patients With Relapsed or Refractory Non-Hodgkin LymphomaCompletedNCT01719250Early Phase 1
- Phase Ib of Abiraterone Acetate Plus BEZ235 or BKM120 in Castration-resistant Prostate Cancer (CRPC) PatientsCompletedNCT01634061Phase 1
- A Phase I Study of BKM120 in Adult Chinese Patients With Advanced Solid TumorsCompletedNCT01626209Phase 1
- Phase I Study of the Oral PI3kinase Inhibitor BKM120 or BYL719 and the Oral PARP Inhibitor Olaparib in Patients With Recurrent Triple Negative Breast Cancer or High Grade Serous Ovarian CancerCompletedNCT01623349Phase 1
- Phase II, Open Label, Non-randomized, Trial of BKM120 for Metastatic or Locally Advanced Cervical CancerWithdrawnNCT01613677Phase 2
- P13Kinase Inhibitor BKM120 in Combination With Panitumumab in Metastatic/Advanced RAS-Wild Type Colorectal Cancer.CompletedNCT01591421Phase 1/2
- Safety and Efficacy of BKM120 and Lapatinib in HER2+/PI3K-activated, Trastuzumab-resistant Advanced Breast CancerTerminatedNCT01589861Phase 1/2
- Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid TumorsCompletedNCT01576666Phase 1
- BKM120 + mFOLFOX6 in Advanced Solid Tumors With Expansion Cohort Pancreatic CancerCompletedNCT01571024Phase 1
- A Trial of Gefitinib in Combination With BKM120 in Patients With Advanced Non-Small Cell Lung Cancer, With Enrichment for Patients Whose Tumours Harbour Molecular Alterations of PI3K Pathway and Known to Overexpress EGFRCompletedNCT01570296Phase 1
- BKM120 in Advanced, Metastatic, or Recurrent Endometrial CancersWithdrawnNCT01550380Phase 2
- PI3K Inhibitor BKM120 and Docetaxel in Treating Patients With Advanced Solid Tumor That is Locally Advanced, Cannot Be Removed By Surgery, or MetastaticCompletedNCT01540253Phase 1
- Study of BKM120 in Advanced Squamous Cell Carcinoma of Head and NeckStatus unknownNCT01527877Phase 2
- Pharmacodynamic Study of BKM120 in Breast CancerCompletedNCT01513356Early Phase 1
- BKM120 in Cancers With PIK3CA Activating MutationsWithdrawnNCT01501604Phase 2
- A Phase I Dose Escalation Study of BKM120 With Radiation Therapy and Temozolomide in Patients With Newly Diagnosed GlioblastomaCompletedNCT01473901Phase 1
- A Phase I Study of BKM120 and Everolimus in Advanced Solid MalignanciesCompletedNCT01470209Phase 1
- A Dose-finding Study of a Combination of Imatinib and BKM120 in the Treatment of 3rd Line GIST PatientsCompletedNCT01468688Phase 1
- GINECO-EN102b - BKM120 as Monotherapy in the Treatment of Initial or Recurrent Metastatic Endometrial CancerCompletedNCT01397877Phase 2
- Study to Assess Safety, Tolerability and Preliminary Efficacy of BKM120, PI3K Kinase Inhibitor, With Advanced LeukemiasCompletedNCT01396499Phase 1
- Safety, Pharmacokinetics and Pharmacodynamics of BKM120 Plus MEK162 in Selected Advanced Solid Tumor PatientsCompletedNCT01363232Phase 1
- BKM120 and Fulvestrant for Treating Postmenopausal Patients With Estrogen Receptor-Positive Stage IV Breast CancerCompletedNCT01339442Phase 1
- A Trial of Irinotecan and BKM120 in Previously Treated Advanced Colorectal CancerCompletedNCT01304602Phase 1
- BKM120 + Carboplatin + Paclitaxel for Patients With Advanced Solid TumorsCompletedNCT01297452Phase 1
- A Trial of Oral BEZ235 and BKM120 in Combination With Paclitaxel With or Without TrastuzumabCompletedNCT01285466Phase 1
- A Study of BKM120 in Adult Japanese Patients With Advanced Solid TumorsCompletedNCT01283503Phase 1
- PhIb BKM120 or BEZ235+Endocrine Treatment in Post-Menopausal Patients With Hormone Receptor + Metastatic Breast CancerCompletedNCT01248494Phase 1
- A Study to Investigate Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of BKM120 Plus GSK1120212 in Selected Advanced Solid Tumor PatientsCompletedNCT01155453Phase 1
- Safety of BKM120 Monotherapy in Advanced Solid Tumor PatientsCompletedNCT01068483Phase 1