Bosutinib: all 51 studies that test it

Page 1 of 1. Open to participants first (2), then studies with results posted, then the rest; newest registration first within each.

• Canadian Profiling and Targeted Agent Utilization Trial (CAPTUR)RecruitingNCT03297606Phase 2
• Study for the Use of TKIs for Treatment of Cognitive Decline Due to Degenerative DementiasEnrolling by invitationNCT02921477Phase 1
• Evaluation of the Relative Bioavailability of Bosutinib Capsules Under Fed Condition and Estimation of Food Effect on Orally Administered Bosutinib CapsuleCompletedNCT05032690Phase 1Results posted
• Bioavailability of Bosutinib Administered as Capsule Contents Mixed With Applesauce or Yogurt Relative to Intact Capsules Under Fed ConditionCompletedNCT04916769Phase 1Results posted
• Safety and Efficacy Evaluation of Bosutinib Plus Atezolizumab in Newly Diagnosed Chronic Leukemia Adult PatientsTerminatedNCT04793399Phase 1/2Results posted
• Impact of Bosutinib on Safety, Tolerability, Biomarkers and Clinical Outcomes in Dementia With Lewy BodiesCompletedNCT03888222Phase 2Results posted
• Study of Bosutinib in Japanese Adult Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous LeukemiaCompletedNCT03128411Phase 2Results posted
• Bosutinib in Treating Patients With Chronic Myeloid Leukemia in Chronic Phase After Frontline TKI FailureTerminatedNCT02906696Phase 2Results posted
• Phase I/II Study of Bosutinib in Combination With Inotuzumab Ozogamicin in CD22-positive PC Positive ALL and CMLCompletedNCT02311998Phase 1/2Results posted
• The Life After Stopping Tyrosine Kinase Inhibitors Study (The LAST Study)CompletedNCT02269267Phase 2Results posted
• Safety And Efficacy Study Of Bosutinib In Patients With Philadelphia Chromosome Positive Chronic Myeloid Leukemia Previously Treated With One Or More Tyrosine Kinase InhibitorsTerminatedNCT02228382Phase 4Results posted
• A Multicenter Phase 3, Open-Label Study of Bosutinib Versus Imatinib in Adult Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous LeukemiaCompletedNCT02130557Phase 3Results posted
• Bosutinib Treatment Extension Study Only For Subjects With Chronic Myeloid Leukemia (CML) Who Have Previously Participated In Bosutinib Studies B1871006 Or B1871008CompletedNCT01903733Not applicableResults posted
• Bosutinib in Adult Patients With Recurrent GlioblastomaCompletedNCT01331291Phase 2Results posted
• Bosutinib For Autosomal Dominant Polycystic Kidney DiseaseCompletedNCT01233869Phase 2Results posted
• Study Of Bosutinib With Capecitabine In Solid Tumors And Locally Advanced Or Metastatic Breast CancerTerminatedNCT00959946Phase 1/2Results posted
• Study Evaluating Bosutinib-Letrozole Combination Versus Letrozole Alone In Post Menopausal Women With Breast CancerTerminatedNCT00880009Phase 2Results posted
• Study Evaluating SKI-606 (Bosutinib) In Japanese Subjects With Philadelphia Chromosome Positive LeukemiasCompletedNCT00811070Phase 2Results posted
• Study Evaluating Bosutinib-Exemestane Combination Vs Exemestane Alone in Post Menopausal Women With Breast CancerTerminatedNCT00793546Phase 2Results posted
• Compare Bosutinib To Imatinib In Subjects With Newly Diagnosed Chronic Phase Philadelphia Chromosome Positive CMLCompletedNCT00574873Phase 3Results posted
• Study Evaluating SKI-606 (Bosutinib) In Subjects With Breast CancerCompletedNCT00319254Phase 2Results posted
• Study Evaluating SKI-606 (Bosutinib) In Philadelphia Chromosome Positive LeukemiasCompletedNCT00261846Phase 2Results posted
• Study Evaluating SKI-606 (Bosutinib) In Advanced Malignant Solid TumorsCompletedNCT00195260Phase 1Results posted
• iPSC-based Drug Repurposing for ALS Medicine (iDReAM) StudyCompletedNCT04744532Phase 1/2
• A Study of REduction And DIscontinuation Treatment of TKI (Imatinib, Nilotinib, Dasatinib and Bosutinib)Status unknownNCT04578847Phase 2
• Bioequivalence Study of Bosutinib Pediatric Capsule Relative to Commercial Tablet Under Fed ConditionCompletedNCT04549480Phase 1
• Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid LeukemiaActive, not recruitingNCT04258943Phase 1/2
• Phase II Study Testing the Tolerability and the Efficacy of Bosutinib in Chronic Phase CML PatientsStatus unknownNCT03205267Phase 2
• Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid TumorsCompletedNCT03023319Phase 1
• Bosutinib in Elderly Chronic Myeloid LeukemiaCompletedNCT02810990Phase 2
• Axitinib and Bosutinib in Treating Patients With Chronic, Accelerated, or Blastic Phase Chronic Myeloid LeukemiaTerminatedNCT02782403Phase 1
• Allogeneic Stem Cell Transplantation in Chronic Myeloid Leukemia Failing TKIs TherapyCompletedNCT02638467Phase 2
• CML Treated With Bosutinib After RelapseCompletedNCT02445742Phase 2
• Absolute Bioavailability Of BosutinibCompletedNCT02192294Phase 1
• Drug Interaction Study Between Bosutinib And DabigatranCompletedNCT02102633Phase 1
• Bioequivalence And Food Effect Study Of Bosutinib In Healthy SubjectsCompletedNCT01374139Phase 1
• Bosutinib In Subjects With Renal ImpairmentCompletedNCT01233882Phase 1
• Study Comparing Two Different Tablet Formulations Of Bosutinib Under Fed ConditionsCompletedNCT01080365Phase 1
• A Study Evaluating Gemcitabine Plus Bosutinib for Patients With Resected Pancreatic CancerTerminatedNCT01025570Phase 1
• Study Evaluating SKI-606 in Subject With Solid TumorsCompletedNCT01001936Phase 1
• Study Evaluating The Potential Effect Of Lansoprazole On The Pharmacokinetics Of Bosutinib In Healthy SubjectsCompletedNCT00952913Phase 1
• Study Comparing Two Different Tablet Formulations Of BosutinibCompletedNCT00934674Phase 1
• Study Evaluating The Effect of Bosutinib (SKI-606) On Cardiac Repolarization (Rhythms Of The Heart)CompletedNCT00914121Phase 1
• Study Evaluating Ascending Single-Dose Of Bosutinib Administered With Multiple Doses Of Ketoconazole To Healthy SubjectsCompletedNCT00777530Phase 1
• Study Evaluating The Pharmacokinetics (PK) And Safety Of Bosutinib In Subjects With Liver Disease And In Healthy SubjectsCompletedNCT00759837Phase 1
• Study Evaluating The Mass Balance And Metabolic Disposition Of SKI-606CompletedNCT00757341Phase 1
• Effect of Rifampin on Bosutinib When Both Are Given to Healthy PeopleCompletedNCT00725426Phase 1
• Study to Determine the Effect of a High-Fat Meal on the Relative Bioavailability and Pharmacokinetics of a Single Dose of Bosutinib Administered Orally to Healthy SubjectsCompletedNCT00721474Phase 1
• Study Evaluating 3 New Formulations of SKI-606 in Healthy Adult SubjectsCompletedNCT00499538Phase 1
• Study Evaluating Drug Interaction Between Multiple Doses of Ketoconazole and a Single Dose of SKI-606CompletedNCT00434486Phase 1
• Study Evaluating SKI-606 Administered to Healthy SubjectsCompletedNCT00406406Phase 1

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