Benralizumab: all 68 studies that test it

Page 1 of 1. Open to participants first (6), then studies with results posted, then the rest; newest registration first within each.

• Fasenra: An Asthma StudyEnrolling by invitationNCT07654842Phase 4
• Roll-over Study for Participants Who Have Completed a Previous Clinical Study With Benralizumab (Fasenra) and Benefit From Continued TreatmentRecruitingNCT07444567Phase 3
• Interest of a Targeted Therapy for the Treatment of a Severe Form of Hypersensitivity to Drug (DRESS Syndrome)Not yet recruitingNCT06734884Phase 2
• A Trial to Investigate Benralizumab in Children With Eosinophilic DiseasesRecruitingNCT06512883Phase 3
• Leveraging Pharmacogenomics in Asthma for Predication, Mechanism and EndotypingRecruitingNCT06385236Phase 4
• BenRalizumab Effect on Airway Remodeling in Severe asTHmaRecruitingNCT06288516Phase 4
• BURAN: Benralizumab on Airway Dynamics in Severe Eosinophilic Asthma Using Functional Respiratory ImagingCompletedNCT05552508Phase 4Results posted
• FAsenra Safety Trial in IndiaCompletedNCT05384938Phase 4Results posted
• Efficacy and Safety of Benralizumab in Patients With Eosinophilic Gastritis and/or Gastroenteritis (The HUDSON GI Study)TerminatedNCT05251909Phase 3Results posted
• Efficacy and Safety of Benralizumab in Patients With Non-cystic Fibrosis BronchiectasisTerminatedNCT05006573Phase 3Results posted
• A Study to Investigate the Use of Benralizumab in Patients With Bullous Pemphigoid.TerminatedNCT04612790Phase 3Results posted
• A Study to Investigate the Use of Benralizumab in Patients With Chronic Spontaneous Urticaria Who Are Symptomatic Despite the Use of Antihistamines (ARROYO)TerminatedNCT04612725Phase 2Results posted
• Efficacy and Safety Study of the Use of Benralizumab for Patients With Moderate to Severe Atopic DermatitisTerminatedNCT04605094Phase 2Results posted
• Study of Benralizumab in People With Skin Side Effects Caused by Cancer TherapiesCompletedNCT04552288Phase 2Results posted
• A Study of Benralizumab in Patients With Eosinophilic EsophagitisTerminatedNCT04543409Phase 3Results posted
• PK/PD and Long Term Safety Study of Benralizumab in Children With Severe Eosinophilic AsthmaCompletedNCT04305405Phase 3Results posted
• A Phase III Study to Evaluate the Efficacy and Safety of Benralizumab in Patients With Hypereosinophilic Syndrome (HES)Active, not recruitingNCT04191304Phase 3Results posted
• A Study to Assess the Reduction of Daily Maintenance ICS/LABA Treatment Towards Anti-Inflammatory Reliever Treatment in Patients With Severe Eosinophilic Asthma Treated With BenralizumabCompletedNCT04159519Phase 4Results posted
• Efficacy and Safety of Benralizumab in EGPA Compared to Mepolizumab.Active, not recruitingNCT04157348Phase 3Results posted
• Efficacy and Safety Study of Benralizumab in Patient With Eosinophilic Chronic Rhinosinusitis With Nasal Polyps (ORCHID)TerminatedNCT04157335Phase 3Results posted
• Effect of Benralizumab in Atopic DermatitisCompletedNCT03563066Phase 2Results posted
• Study to Evaluate Efficacy and Safety of Benralizumab in Reducing Oral Corticosteroid Use in Adult Patients With Severe AsthmaCompletedNCT03557307Phase 3Results posted
• Benralizumab for Eosinophilic Gastritis (BEGS)CompletedNCT03473977Phase 2/3Results posted
• Benralizumab Effect on Severe Chronic Rhinosinusitis With Eosinophilic PolyposisCompletedNCT03450083Phase 2Results posted
• Efficacy and Safety Study of Benralizumab for Patients With Severe Nasal PolyposisCompletedNCT03401229Phase 3Results posted
• Efficacy and Safety Study of Benralizumab in Patients With Uncontrolled Asthma on Medium to High Dose Inhaled Corticosteroid Plus LABA (MIRACLE)CompletedNCT03186209Phase 3Results posted
• A Study of the Safety and Effectiveness of Benralizumab to Treat Patients With Severe Uncontrolled Asthma.CompletedNCT03170271Phase 3Results posted
• Pharmacokinetic Comparability of Benralizumab Using Accessorized Pre-Filled Syringe or Autoinjector in Healthy VolunteersCompletedNCT02968914Phase 1Results posted
• Study to Assess Functionality, Reliability, and Performance of a Single-Use Auto-Injector With Benralizumab Administered at HomeCompletedNCT02918071Phase 3Results posted
• A Study to Evaluate the Onset of Effect and Time Course of Change in Lung Function With Benralizumab in Severe, Uncontrolled Asthma Patients With Eosinophilic InflammationCompletedNCT02869438Phase 3Results posted
• Study to Evaluate the Effect of Benralizumab on Allergen-Induced Inflammation in Mild, Atopic AsthmaticsCompletedNCT02821416Phase 3Results posted
• Study to Evaluate the Potential Effect of Benralizumab on the Humoral Immune Response to the Seasonal Influenza Vaccination in Adolescent and Young Adult Patients With Severe AsthmaCompletedNCT02814643Phase 3Results posted
• A Safety Extension Study With Benralizumab for Asthmatic Adults on Inhaled Corticosteroid Plus Long-acting β2 AgonistCompletedNCT02808819Phase 3Results posted
• Study to Assess Functionality, Reliability, and Performance of a Pre-filled Syringe With Benralizumab Administered at HomeCompletedNCT02417961Phase 3Results posted
• Study to Evaluate the Efficacy and Safety of Benralizumab in Adult Patients With Mild to Moderate Persistent AsthmaCompletedNCT02322775Phase 3Results posted
• A Safety Extension Study to Evaluate the Safety and Tolerability of Benralizumab (MEDI-563) in Asthmatic Adults and Adolescents on Inhaled Corticosteroid Plus LABACompletedNCT02258542Phase 3Results posted
• Study to Evaluate Safety and Efficacy of Benralizumab in Subjects With Hypereosinophilic SyndromeStatus unknownNCT02130882Phase 2/3Results posted
• Efficacy and Safety Study of Benralizumab to Reduce OCS Use in Patients With Uncontrolled Asthma on High Dose Inhaled Corticosteroid Plus LABA and Chronic OCS TherapyCompletedNCT02075255Phase 3Results posted
• Efficacy and Safety Study of Benralizumab Added to Medium-dose Inhaled Corticosteroid Plus LABA in Patients With Uncontrolled AsthmaTerminatedNCT01947946Phase 3Results posted
• Efficacy and Safety Study of Benralizumab Added to High-dose Inhaled Corticosteroid Plus LABA in Patients With Uncontrolled AsthmaCompletedNCT01928771Phase 3Results posted
• Efficacy and Safety Study of Benralizumab in Adults and Adolescents Inadequately Controlled on Inhaled Corticosteroid Plus Long-acting β2 AgonistCompletedNCT01914757Phase 3Results posted
• Study to Evaluate the Efficacy and Safety of MEDI-563 in Adults With Uncontrolled AsthmaCompletedNCT01238861Phase 2Results posted
• A Study to Evaluate the Effectiveness of MEDI-563 in Subjects With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT01227278Phase 2Results posted
• A Phase 2a Study to Evaluate the Safety and Tolerability of Benralizumab (MEDI-563) in Adults With AsthmaCompletedNCT00783289Phase 2Results posted
• A Phase 2 Study to Evaluate the Safety and Efficacy of Intravenously Administered Benralizumab (MEDI-563).CompletedNCT00768079Phase 2Results posted
• Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA TreatmentCompletedNCT06750289Phase 3
• STEP: Phase IIIb Study of Benralizumab to Step-down Maintenance Therapy in Patients With Severe Eosinophilic AsthmaCompletedNCT06465485Phase 3
• A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic AsthmaActive, not recruitingNCT05692180Phase 3
• Benralizumab in Chronic Prurigo - Investigating Clinical Efficacy (BICPIC)WithdrawnNCT05528913Phase 2
• Immunological Basis for Benralizumab Activity in Chronic Obstructive Pulmonary Disease (COPD)Status unknownNCT05273359Phase 2
• Benralizumab Initiated During Severe Asthma AttackStatus unknownNCT04617171Phase 2
• NAsal Polyps: Inflammatory & Molecular Phenotyping of Responders to BenralizumabCompletedNCT04185012Phase 3
• Benralizumab in the Treatment of Patients With Severe Asthma With ABPAWithdrawnNCT04108962Phase 4
• Benralizumab Exacerbation StudyCompletedNCT04102800Phase 4
• Acute Exacerbations Treated With BenRAlizumab (The ABRA Study)Status unknownNCT04098718Phase 2
• Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent ExacerbationsCompletedNCT04053634Phase 3
• Benralizumab Airway Remodeling Study in Severe Eosinophilic AsthmaticsActive, not recruitingNCT03953300Phase 4
• Pharmacokinetic Study of Benralizumab in Healthy Chinese SubjectsCompletedNCT03928262Phase 1
• Evaluating the Effect of Benralizumab in Severe, Poorly-controlled Eosinophilic Asthma Using Inhaled Hyperpolarized 129-Xenon MRIActive, not recruitingNCT03733535Not applicable
• Impact of Benralizumab Treatment on Circulating Dendritic Cells in Patients With Eosinophilic AsthmaStatus unknownNCT03652376Phase 4
• Benralizumab in Patients With Inadequate Response to Anti-IL5 Monoclonal Antibody TherapiesCompletedNCT03470311Phase 3
• The Effect of Benralizumab on Exercise-induced BronchoconstrictionStatus unknownNCT03327701Phase 3
• Treatment of Chronic Urticarial Unresponsive to H1-antihistamines With an Anti-IL5Ralpha Monoclonal AntibodyCompletedNCT03183024Phase 4
• Benralizumab in the Treatment of Eosinophilic Granulomatosis With Polyangiitis (EGPA) StudyStatus unknownNCT03010436Phase 2
• Study of Benralizumab (KHK4563) in Patients With Eosinophilic Chronic RhinosinusitisCompletedNCT02772419Phase 2
• A Phase IIa Study of KHK4563CompletedNCT01412736Phase 2
• A Study to Evaluate the Safety, Tolerability and Effects of MEDI-563 in Adults With AsthmaCompletedNCT00659659Phase 1
• A Sequential Dose-Escalation Study in Subjects With Mild AsthmaCompletedNCT00512486Phase 1

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