Angiotensin Receptor Antagonists: all 1,100 studies that test it

Page 2 of 11. Open to participants first (75), then studies with results posted, then the rest; newest registration first within each.

• Open-label Extension Study to Evaluate Long-term Safety of Sacubitril/Valsartan in Pediatric Patients With HFCompletedNCT03785405Phase 3Results posted
• A Study of the Effect and Safety of Sparsentan in the Treatment of Patients With IgA NephropathyCompletedNCT03762850Phase 3Results posted
• Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 1TerminatedNCT03738878Phase 4Results posted
• The Effects of Sacubitril/Valsartan Compared to Valsartan on LV Remodelling in Asymptomatic LV Systolic Dysfunction After MICompletedNCT03552575Phase 3Results posted
• Circulating NEP and NEP Inhibition Study in Heart Failure With Preserved Ejection FractionCompletedNCT03506412Phase 4Results posted
• Study of Sparsentan in Patients With Primary Focal Segmental Glomerulosclerosis (FSGS)CompletedNCT03493685Phase 3Results posted
• Losartan for the Treatment of Pediatric NAFLDTerminatedNCT03467217Phase 2Results posted
• N-of-1 Trials In Children With HypertensionCompletedNCT03461003Phase 4Results posted
• A Phase 1 Food Effect Study of Azilsartan (TAK-536) Pediatric FormulationCompletedNCT03434977Phase 1Results posted
• ACES - ACE Inhibitors Combined With Exercise for Seniors With HypertensionCompletedNCT03295734Phase 2Results posted
• Losartan and Inflammation in Cystic FibrosisTerminatedNCT03206788Phase 2Results posted
• A Randomized, Double-blind Controlled Study Comparing LCZ696 to Medical Therapy for Comorbidities in HFpEF PatientsCompletedNCT03066804Phase 3Results posted
• A Phase 1, Bio-equivalence Study of TAK-536 Pediatric FormulationCompletedNCT03042299Phase 1Results posted
• An Open-Label Trial of Losartan Potassium in Participants With Eosinophilic Esophagitis (EoE)CompletedNCT03029091Phase 2Results posted
• Prospective ARNI vs ACE Inhibitor Trial to DetermIne Superiority in Reducing Heart Failure Events After MICompletedNCT02924727Phase 3Results posted
• randOmized stUdy Using acceleromeTry to Compare Sacubitril/valsarTan and Enalapril in Patients With Heart FailureCompletedNCT02900378Phase 3Results posted
• Effects of Sacubitril/Valsartan Therapy on Biomarkers, Myocardial Remodeling and Outcomes.CompletedNCT02887183Phase 4Results posted
• Efficacy and Safety of LCZ696 Compared to Valsartan on Cognitive Function in Patients With Chronic Heart Failure and Preserved Ejection FractionCompletedNCT02884206Phase 3Results posted
• Study of Effects of Sacubitril/Valsartan vs. Enalapril on Aortic Stiffness in Patients With Mild to Moderate HF With Reduced Ejection FractionCompletedNCT02874794Phase 4Results posted
• EntrestoTM (LCZ696) In Advanced Heart Failure (LIFE Study)CompletedNCT02816736Phase 4Results posted
• A Phase 3 Long-term Study of TAK-536 in Pediatric Patients 6 to Less Than 16 Years With HypertensionCompletedNCT02791438Phase 3Results posted
• Exercise Capacity Study of LCZ696 vs. Enalapril in Patients With Chronic Heart Failure and Reduced Ejection Fraction.CompletedNCT02768298Phase 4Results posted
• Demonstration of Reverse Remodeling Effects of Entresto. Using Echocardiography Endocardial Surface AnalysisCompletedNCT02754518Phase 4Results posted
• Left Atrial Mechanical Function Improvement After Atrial Fibrillation Catheter AblationCompletedNCT02734355Phase 4Results posted
• A Controlled Trial of Losartan in Posttraumatic Stress DisorderCompletedNCT02709018Not applicableResults posted
• A Clinical Trial to Evaluate the Pharmacokinetics and Safety of Fimasartan and Rosuvastatin in Healthy Male SubjectsCompletedNCT02704702Phase 1Results posted
• Losartan Effects on Emphysema ProgressionCompletedNCT02696564Phase 4Results posted
• Description of Tolerability of LCZ696 (Sacubitril / Valsartan) in Heart Failure With Reduced Ejection Fraction (HFrEF) Treated in Real Life SettingCompletedNCT02690974Phase 4Results posted
• Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LCZ696 Followed by a 52-week, Double-blind Study of LCZ696 Compared With Enalapril in Pediatric Patients With Heart FailureCompletedNCT02678312Phase 2/3Results posted
• Comparison of Pre- and Post-discharge Initiation of LCZ696 Therapy in HFrEF Patients After an Acute Decompensation EventCompletedNCT02661217Phase 4Results posted
• Candesartan's Effects on Alzheimer's Disease And Related BiomarkersCompletedNCT02646982Phase 2Results posted
• Use of Entresto Sacubitril/Valsartan for the Treatment of Peripheral Arterial DiseaseTerminatedNCT02636283Phase 2Results posted
• Angiotensin Receptors and Age Related Mitochondrial Decline in HIV PatientsTerminatedNCT02606279Not applicableResults posted
• Telmisartan Plus Exercise to Improve Functioning in Peripheral Artery DiseaseCompletedNCT02593110Not applicableResults posted
• Comparison of Sacubitril/Valsartan Versus Enalapril on Effect on NT-proBNP in Patients Stabilized From an Acute Heart Failure Episode.CompletedNCT02554890Phase 4Results posted
• A Single- and Multiple-Dose Study of the Pharmacokinetics of TAK-491 in Healthy Chinese ParticipantsCompletedNCT02541669Phase 1Results posted
• Azilsartan Medoxomil in the Treatment of Essential Hypertension and Type 2 Diabetes in AsiaCompletedNCT02517866Phase 4Results posted
• Azilsartan Medoxomil (TAK-491) Compared to Valsartan in Chinese Participants With HypertensionCompletedNCT02480764Phase 3Results posted
• Health Evaluation in African Americans Using RAS TherapyCompletedNCT02471833Phase 1/2Results posted
• Study of Efficacy and Safety of LCZ696 in Japanese Patients With Chronic Heart Failure and Reduced Ejection FractionCompletedNCT02468232Phase 3Results posted
• A Phase 3 Pharmacokinetic Study of TAK-536 (Azilsartan) in Pediatric Patients 6 to Less Than 16 Years With HypertensionCompletedNCT02451150Phase 3Results posted
• Effect of Losartan on Airway Mucociliary Dysfunction in Patients With COPD and Chronic BronchitisTerminatedNCT02416102Phase 4Results posted
• A Bioequivalence Study of TAK-536 Pediatric FormulationCompletedNCT02401464Phase 1Results posted
• Pharmacokinetic Interaction Between HGP0904, HGP0608 and HGP1405CompletedNCT02387554Phase 1Results posted
• Preventing Sickle Cell Kidney DiseaseTerminatedNCT02373241Phase 2Results posted
• INTERVENCION TrialCompletedNCT02373163Phase 4Results posted
• Study of TelmisartanFor the Prevention of Acute GVHD Post Allogeneic Hematopoietic Stem Cell TransplantationTerminatedNCT02338232Not applicableResults posted
• Phase 1/2 Prospective Double-Blind Placebo-Controlled Randomized Clinical Trial of Losartan to Treat Grade II & III Hamstring StrainsTerminatedNCT02263729Phase 1/2Results posted
• Efficacy and Safety Evaluating Study to Compare Kanarb (Fimasartan) and Cozaar® (Losartan) in Adult Patients With Grade I-II Arterial HypertensionCompletedNCT02248961Phase 3Results posted
• Safety and Tolerability During Open-label Treatment With LCZ696 in Patients With CHF and Reduced Ejection FractionCompletedNCT02226120Phase 3Results posted
• Azilsartan Medoxomil (TAK-491) Compared to Placebo in Korean Adults With HypertensionCompletedNCT02203916Phase 3Results posted
• Fixed Dose Intervention Trial of New England Enhancing Survival in SMI PatientsCompletedNCT02188121Phase 4Results posted
• Pharmacokinetics of Different Formulations of Telmisartan, Amlodipine, and Hydrochlorothiazide (HCTZ) in Japanese Healthy Male VolunteersCompletedNCT02183675Phase 1Results posted
• Ambulatory vs Office BP Management Usual Care for Diagnosing and Managing Hypertension: A Pilot StudyCompletedNCT02121041Not applicableResults posted
• A Study to Explore the Effects of Azilsartan Compared to Telmisartan on Insulin Resistance of Patients With Essential Hypertension on Type 2 Diabetes Mellitus by HOMA-RCompletedNCT02079805Phase 4Results posted
• Study of Efficacy and Safety of CVAA489 in Hypertensive PatientsCompletedNCT02062645Phase 4Results posted
• Losartan to Reduce Inflammation and Fibrosis Endpoints in HIV TrialCompletedNCT02049307Phase 2Results posted
• A Study of Muscle Strength Maintenance in Older AdultsCompletedNCT01989793Phase 2Results posted
• CAndesartan vs LIsinopril Effects on the BRainCompletedNCT01984164Phase 2Results posted
• Cardiomyopathy in DMD: Lisinopril vs. LosartanCompletedNCT01982695Not applicableResults posted
• Drug-Drug Interaction Study to Evaluate the Effect of Colestilan on the Pharmacokinetics of Single Doses of Candesartan Cilexetil in Healthy SubjectsCompletedNCT01976572Phase 1Results posted
• A Pilot Study of Candesartan as a Treatment for Cocaine DependenceTerminatedNCT01938664Phase 2Results posted
• Telmisartan to Reduce AIDS-Related Fibrotic and Inflammatory Contributors (TRAFIC Study)CompletedNCT01928927Phase 2Results posted
• Safety and Tolerability of Initiating LCZ696 in Heart Failure PatientsCompletedNCT01922089Phase 2Results posted
• Efficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients With Preserved Ejection FractionCompletedNCT01920711Phase 3Results posted
• Efficacy and Safety of Valsartan 160mg and Rosuvastatin 20mg in Patients With Hypertension and HyperlipidemiaCompletedNCT01918332Phase 3Results posted
• Study of Losartan in the Treatment of NAFLD in ChildrenCompletedNCT01913470Phase 2Results posted
• HALT Progression of Polycystic Kidney Disease Study BCompletedNCT01885559Phase 3Results posted
• Efficacy and Safety of LCZ696 Compared to Olmesartan in Essential Hypertensive Patients Not Responsive to OlmesartanCompletedNCT01876368Phase 3Results posted
• A Study to Evaluate the Effect of LCZ696 on Aortic Stiffness in Subjects With HypertensionCompletedNCT01870739Phase 2Results posted
• Reversing Tissue Fibrosis to Improve Immune Reconstitution in HIVCompletedNCT01852942Phase 2Results posted
• Radiation w/FOLFIRINOX-Losartan for Pancreatic CancerCompletedNCT01821729Phase 2Results posted
• Testing Effectiveness of Losartan in Patients With EoE With or Without a CTDCompletedNCT01808196Phase 2Results posted
• Effects of Cerebral Hypoperfusion and Its Reversal on Late-Life DepressionTerminatedNCT01794455Phase 4Results posted
• Efficacy and Safety of LCZ696 in Comparison to Olmesartan in Asian Patients With Essential HypertensionCompletedNCT01785472Phase 3Results posted
• Effect of Azilsartan on Aldosterone in Postmenopausal FemalesCompletedNCT01774591Not applicableResults posted
• Study to Evaluate Effect of Belatacept on Pharmacokinetics of Inje Cocktail in Healthy VolunteersCompletedNCT01766050Phase 4Results posted
• Azilsartan Circadian and Sleep PressureCompletedNCT01762501Not applicableResults posted
• Study of the Safety and Efficacy of LCZ696 on Arterial Stiffness in Elderly Patients With HypertensionCompletedNCT01692301Phase 2Results posted
• Angiotensin II Blockade and Inflammation in ObesityCompletedNCT01684748Phase 4Results posted
• Assessment of LCZ696 and Valsartan in Asian Patients With Salt-sensitive HypertensionCompletedNCT01681576Phase 2Results posted
• CR Aim #2 - AT1 Receptor Blockade & ACE Inhibition Effect on Humoral FunctionCompletedNCT01678794Phase 1/2Results posted
• Efficacy and Safety of LCZ696 200 mg + Amlodipine 5 mg in Comparison With Amlodipine 5 mg in Hypertensive Patients Not Responding to AmlodipineCompletedNCT01663233Phase 3Results posted
• Safety and Tolerability and Efficacy of LCZ696 in Japanese Severe Hypertensive PatientsCompletedNCT01646671Phase 3Results posted
• Study of Cardiovascular Disease and Obstructive Sleep ApneaCompletedNCT01637623Phase 2Results posted
• Evaluation of the Metabolic Effects of LCZ696 and Amlodipine in Obese Hypertensive SubjectsCompletedNCT01631864Phase 2Results posted
• Comparison of the Effect of Eprosartan and Eprosartan Mesylate on Blood Pressure in Essential HypertensionCompletedNCT01631227Phase 3Results posted
• A Study of LCZ696 in Subjects With Mild and Moderate Hepatic Impairment Compared With Normal Healthy VolunteersCompletedNCT01621633Phase 2Results posted
• Efficacy, Safety and Tolerability of Multiple Doses of Valsartan in Children With Hypertension With or Without CKDCompletedNCT01617681Phase 3Results posted
• Efficacy and Safety of LCZ696 in Comparison to Olmesartan in Elderly Patients With Essential HypertensionCompletedNCT01615198Phase 3Results posted
• Randomized, Double-Blind, Safety and Efficacy Study of RE-021 (Sparsentan) in Focal Segmental GlomerulosclerosisCompletedNCT01613118Phase 2Results posted
• Comparison Between Losartan and Benazepril in Diabetic Hypertensive Patients Not Controlled by AmlodipineCompletedNCT01603940Phase 4Results posted
• Evaluation of Drug-drug Interaction Between LCZ696 and Sildenafil in Subjects With Mild to Moderate HypertensionCompletedNCT01601470Phase 2Results posted
• Efficacy and Safety of LCZ696 in Comparison to Olmesartan in Japanese Patients With Essential HypertensionCompletedNCT01599104Phase 3Results posted
• Safety and Tolerability and Efficacy of LCZ696 in Japanese Hypertensive Patients With Renal DysfunctionCompletedNCT01593787Phase 3Results posted
• A Clinical Trial for People HIV+ Age > 50 at Risk for Heart DiseaseCompletedNCT01578772Phase 2Results posted
• Pharmacokinetics of LCZ696 in Subjects With Mild and Moderate Renal Impairment Compared to Healthy Subjects With Normal Renal FunctionCompletedNCT01569815Phase 1Results posted
• Effects of Losartan and Antiretroviral Regimen Containing Raltegravir in Fibrosis Inflammation Mediators, Cardiovascular Risk and Neurocognitive Disorders in HIV Infected Patients Previously Effectively TreatedCompletedNCT01529749Phase 4Results posted
• Efficacy and Safety of Azilsartan Medoxomil Used in Combination With Metformin in Participants With Hypertension and DiabetesTerminatedNCT01496430Phase 3Results posted
• Losartan to Reverse Sickle NephropathyCompletedNCT01479439Phase 2Results posted

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