Alkylating agents: all 3,295 studies that test it
Page 22 of 33. Open to participants first (456), then studies with results posted, then the rest; newest registration first within each.
- Cellular Immunotherapy Following Chemotherapy in Treating Patients With Recurrent Non-Hodgkin Lymphomas, Chronic Lymphocytic Leukemia, or B-Cell Prolymphocytic LeukemiaActive, not recruitingNCT02153580Phase 1
- A Phase II Multi-center Pilot Study of Concurrent Temozolomide and Whole Brain Irradiation in Lung Cancer and Breast Cancer Patients With Brain MetastasesStatus unknownNCT02133677Phase 2
- Targeted Marrow Irradiation, Fludarabine Phosphate, and Busulfan Before Donor Progenitor Cell Transplant in Treating Patients With Hematologic MalignanciesCompletedNCT02129582Phase 1
- Organ-Sparing Marrow-Targeted Irradiation Before Stem Cell Transplant in Treating Patients With High-Risk Hematologic MalignanciesCompletedNCT02122081Phase 1
- Alternating Systemic Chemotherapy and Intra-Arterial Melphalan (IAM) Chemotherapy in Children With Intra-Ocular RetinoblastomaTerminatedNCT02116959Phase 1
- Carfilzomib/SAHA Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant in MyelomaWithdrawnNCT02114502Phase 2
- Microdose Study of Melphalan, Bortezomib and DexamethasoneStatus unknownNCT02109861Early Phase 1
- Concurrent Chemotherapy and Radiation Therapy for Newly Diagnosed Nasal NK Cell LymphomaActive, not recruitingNCT02106988Phase 2
- Mitomicin C for Prevention Postoperative Endoscopic Sinus Surgery Synechia and QOL in Chronic RhinosinusitisCompletedNCT02106793Phase 3
- Multidisciplinary Approach for Poor Prognosis Sinonasal Tumors in Inoperable PatientsStatus unknownNCT02099188Phase 2
- Multidisciplinary Approach for Poor Prognosis Sinonasal Tumors in Operable PatientsStatus unknownNCT02099175Phase 2
- Carfilzomib, Bendamustine Hydrochloride, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple MyelomaCompletedNCT02095834Phase 1
- Total Marrow and Lymphoid Irradiation and Chemotherapy Before DSCT in Treating Patients With High-Risk ALL or AMLActive, not recruitingNCT02094794Phase 2
- Preoperative Chemoradiation for GlioblastomaCompletedNCT02092038Phase 1
- Tolerability and Efficacy of Modified VCD Regimens in Previously Untreated Multiple Myeloma.Status unknownNCT02086942Phase 2
- Fludarabine Phosphate, Clofarabine, and Busulfan With Vorinostat in Treating Patients With Acute Leukemia in Remission or Relapse Undergoing Donor Stem Cell TransplantCompletedNCT02083250Phase 1
- Bortezomib, Dexamethasone, and Cyclophosphamide in Treating Older Patients With Multiple MyelomaWithdrawnNCT02082405Phase 2
- Investigating Bladder Chemotherapy Instead of Surgery for Low Risk Bladder CancerCompletedNCT02070120Phase 2
- Combo of Abraxane, TMZ, Bevacizumab in Metastatic Melanoma With Brain MetastasesWithdrawnNCT02065466Phase 1/2
- CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell TransplantActive, not recruitingNCT02061800Phase 1/2
- NY-ESO-1 Specific T Cells After Cyclophosphamide in Treating Patients With Advanced Synovial Sarcoma or Myxoid/Round Cell LiposarcomaWithdrawnNCT02059850Phase 1
- Allogeneic or Haploidentical Stem Cell Transplant Followed By High-Dose Cyclophosphamide in Treating Patients With Relapsed or Refractory Acute Myeloid LeukemiaTerminatedNCT02057770Phase 1
- Reduced Intensity Conditioning (RIC) Regimen and Post-transplant Cyclophosphamide in Haploidentical Bone Marrow Transplantation in in Patients With Poor Prognosis LymphomasStatus unknownNCT02049580Phase 2
- Targeted Busulfan, Fludarabine, Etoposide Conditioning Regimen for HSCT in Childhood and Adolescent ALL.Status unknownNCT02047578Phase 2
- Phase II Multicenter, Open-label, Single Arm Clinical Study of Pomalidomide and dexamethasonE and CyclophosphamideCompletedNCT02046915Phase 2
- Ketogenic Diet With Radiation and Chemotherapy for Newly Diagnosed GlioblastomaTerminatedNCT02046187Phase 1/2
- Targeted Busulfan, Fludarabine Conditioning Regimen for Hematopoietic Stem Cell Transplantation in GRDStatus unknownNCT02034630Phase 1/2
- The Use of MMC During PRK and Its Effect on Postoperative Topical Steroid RequirementsStatus unknownNCT02030990Phase 2/3
- N2012-01: Phase 1 Study of Difluoromethylornithine (DFMO) and Celecoxib With Cyclophosphamide/TopotecanCompletedNCT02030964Phase 1
- Efficacy and Safety of Atorvastatin in Combination With Radiotherapy and Temozolomide in GlioblastomaCompletedNCT02029573Phase 2
- Combination of G-CSF, Bortezomib, Cyclophosphamide and Dexamethasone in Patients With Multiple MyelomaStatus unknownNCT02027220Phase 2
- Study of Sequential High-dose Chemotherapy in Children With High Risk MedulloblastomaTerminatedNCT02025881Phase 1/2
- Cetuximab Compared to Mitomycin-C and 5-Fluorouracil for Locally Advanced Squamous Cell Carcinomas of the Head and NeckTerminatedNCT02015650Phase 4
- Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation in Children and AdolescentsStatus unknownNCT02014506Phase 1/2
- BENdamustine at Elevated Dose for Relapsed Follicular Lymphoma in Intensification Therapy and Transplantation (BENEFIT)TerminatedNCT02008006Phase 2
- Moderate-dose Cyclophosphamide for Childhood Acquired Aplastic AnemiaStatus unknownNCT01995331Phase 4
- Rituximab Plus Bendamustine as Front Line Treatment in Frail Elderly (>70 Years) Patients With DLBCL: a Phase II Multicenter Study of the FILStatus unknownNCT01990144Phase 2
- Ph 1/2 CTO With Lomustine for Bevacizumab-Naive Recurrent GliomaTerminatedNCT01989052Phase 1
- Bevacizumab in Combination With Chemotherapy in the Neo-adjuvant Setting for HER2 (-) Breast CancerTerminatedNCT01985841Phase 2
- Sequential Administration of FE75C and Docetaxel Versus Docetaxel/Cyclophosphamide in HER-2 Negative, Node Positive Breast CancerCompletedNCT01985724Phase 3
- Pemetrexed and Temozolomide in Treating Patients With Relapsed Primary Central Nervous System Lymphoma （PCNSL）Status unknownNCT01985451Phase 2
- A Study Using Radiation Therapy and Temozolomide to Treat Glioblastoma in Patients Over 70Active, not recruitingNCT01985087Phase 1/2
- Study of ASC-101 in Patients With Hematologic Malignancies Who Receive Dual-cord Umbilical Cord Blood TransplantationStatus unknownNCT01983761Phase 1/2
- Prospective, Multicentric, Phase II Randomized Controlled Trial on Two Parallel Groups Comparing the Efficacy of Two Immunosuppressive Drugs (methotrexate, Cyclophosphamide) in Large Granular Lymphocytes LeukemiaCompletedNCT01976182Phase 2
- Comparative Study of Rituximab Versus Combination of Rituximab and Intravenous Cyclophosphamide in Severe PemphigusStatus unknownNCT01974518Phase 3
- Efficacy Study Comparing Velcade Dexamethasone Thalidomide Versus Velcade Cyclophosphamide Dexamethasone as Induction Treatment in the Initial Management of Multiple Myeloma (IFM2013-04)CompletedNCT01971658Phase 3
- Induction Preoperative Chemotherapy for Patients With Locally Advanced Triple Negative Breast CancerCompletedNCT01969032Phase 2
- Gene Therapy After Frontline Chemotherapy in Treating Patients With AIDS-Related Non-Hodgkin LymphomaActive, not recruitingNCT01961063Phase 1
- Dose Monitoring of Busulfan and Combination Chemotherapy in Hodgkin or Non-Hodgkin Lymphoma Undergoing Stem Cell TransplantCompletedNCT01959477Early Phase 1
- Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed GlioblastomaCompletedNCT01957956Early Phase 1
- iC9-GD2-CAR-VZV-CTLs/Refractory or Metastatic GD2-positive Sarcoma and NeuroblastomaActive, not recruitingNCT01953900Phase 1
- The Efficacy of 5-fluorouracil/Mitomycin for the Patients With Pulmonary Metastasis of Hepatocellular CarcinomaWithdrawnNCT01953406Phase 2
- Metronomic Cyclophosphamide in Combination With Standard Chemotherapy for Squamous Cell Lung CarcinomaStatus unknownNCT01947062Phase 3
- Stereotactic Body Radiation Therapy and T-Cell Infusion in Treating Patients With Metastatic Kidney CancerTerminatedNCT01943188Phase 1
- Bortezomib, Melphalan, and Total-Body Irradiation Before Stem Cell Transplant in Treating Patients With Multiple MyelomaCompletedNCT01936090Phase 1
- Phase Ib/II Study of Buparlisib Plus Carboplatin or Lomustine in Patients With Recurrent Glioblastoma MultiformeCompletedNCT01934361Phase 1
- A Phase II Study for Patients With Indolent Non-follicular Non-Hodgkin's LymphomaCompletedNCT01929265Phase 2
- Busulfan and Melphalan Conditioning in Multiple MyelomaStatus unknownNCT01923935Phase 2
- A Novel "Pediatric-Inspired" Regimen With Reduced Myelosuppressive Drugs for Adults (Aged 18-60) With Newly Diagnosed Ph Negative Acute Lymphoblastic LeukemiaActive, not recruitingNCT01920737Phase 2
- Intravesical Adjuvant Electromotive Mitomycin-CCompletedNCT01920269Phase 2/3
- A Phase II Trial of Adjuvant Radiotherapy Combined With Chemotherapy for Patients With High-risk Endometrial CancerCompletedNCT01918124Phase 2
- Bortezomib (Velcade®), Lenalidomide (Revlimid®) and IV Busulfan (Busilvex®) in Patients Under 65 Years OldCompletedNCT01916252Phase 3
- Phase II Pilot Study Assessing Efficacy of a Cisplatin - Metronomic Cyclophosphamide Treatment in Patients With Metastatic Triple Negative Breast Cancer Resistant to Anthracyclines and TaxanesTerminatedNCT01910870Phase 2
- Phase II Pilot Study Assessing Efficacy of a Cisplatin - Métronomic Cyclophosphamide Treatment in Patients With Stade IV Triple Negative Breast Cancer Secondary Resistant to Anthracyclines and TaxanesTerminatedNCT01910844Phase 2
- Combination Vaccine Immunotherapy (DRibbles) for Patients With Definitively-Treated Stage III Non-small Cell Lung CancerCompletedNCT01909752Phase 2
- A Trail of Neoadjuvant Endostar in Combination With Chemotherapy in Breast CancerStatus unknownNCT01907529Phase 2/3
- Disulfiram in Treating Patients With Glioblastoma Multiforme After Radiation Therapy With TemozolomideCompletedNCT01907165Early Phase 1
- A Phase II Study Evaluating Intravenous Melphalan With Autologous Whole Blood Stem Cell Transplantation Over Three Cycles In Patients With Castration-Resistant Prostate Cancer (MEL-CAP)TerminatedNCT01907009Phase 2/3
- Temozolomide as Maintenance Therapy in Small Cell Lung CancerStatus unknownNCT01900951Phase 2
- Bendamustine Hydrochloride, Clofarabine, and Etoposide in Treating Younger Patients With Relapsed or Refractory Hematologic MalignanciesCompletedNCT01900509Phase 1
- A Phase I Study of High-dose L-methylfolate in Combination With Temozolomide and Bevacizumab in Recurrent High Grade GliomaCompletedNCT01891747Phase 1
- Capecitabine + Bendamustine in Women With Pretreated Locally Advanced or Metastatic Her2-negative Breast CancerCompletedNCT01891227Phase 2
- Myocet + Cyclophosphamide + Metformin Vs Myocet + Cyclophosphamide in 1st Line Treatment of HER2 Neg. Metastatic Breast Cancer PatientsCompletedNCT01885013Phase 2
- Bendamustine, Gemcitabine and Vinorelbine (BeGEV) as Induction Therapy in Relapsed/Refractory Hodgkin's Lymphoma PatientsStatus unknownNCT01884441Phase 2
- Tumor-Infiltrating Lymphocytes And Low-Dose Interleukin-2 Therapy Following Cyclophosphamide And Fludarabine In Patients With MelanomaCompletedNCT01883323Phase 2
- Paclitaxel, Ifosfamide and Cisplatin (TIP) Versus Bleomycin, Etoposide and Cisplatin (BEP) for Patients With Previously Untreated Intermediate- and Poor-risk Germ Cell TumorsActive, not recruitingNCT01873326Phase 2
- Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified ChemotherapyActive, not recruitingNCT01871766Phase 2
- Opsoclonus Myoclonus Syndrome/Dancing Eye Syndrome (OMS/DES) in Children With and Without Neuroblastoma (NBpos and NBneg)Opsoclonus Myoclonus Syndrome/Dancing Eye Syndrome (OMS/DES) in Children With and Without Neuroblastoma (NBpos and NBneg)CompletedNCT01868269Phase 3
- Irinotecan and Temozolomide in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Patients With Newly Diagnosed Ewing SarcomaActive, not recruitingNCT01864109Phase 2
- Low-dose VS High-dose IV Cyclophosphamide for Proliferative LN in ChildrenTerminatedNCT01861561Phase 4
- A Comparison of Continuous Bevacizumab (Avastin) Treatment or Placebo in Addition to Lomustine Followed by Standard of Care After Disease Progression in Participants With GlioblastomaCompletedNCT01860638Phase 2
- Phase I Study of Olaparib and Temozolomide for Ewings Sarcoma or RhabdoomyosarcomaCompletedNCT01858168Phase 1
- Phase II Study Temozolomide for Retinoblastoma Metastatic to the Central Nervous System for Patients From GuatemalaTerminatedNCT01857752Phase 2
- Study of Weekly Carfilzomib, Cyclophosphamide and Dexamethasone In Newly Diagnosed Multiple Myeloma Patients (wCCyd)CompletedNCT01857115Phase 1/2
- Adavosertib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent GlioblastomaCompletedNCT01849146Phase 1
- Temozolomide in Relapsed or Advanced Anaplastic Oligodendroglioma and Oligoastrocytoma: Single-arm, Phase II TrialCompletedNCT01847235Phase 2
- Phase II Study of Concomitant Intensity-modulated Radiotherapy Combined to Capecitabine, Mitomycin and Panitumumab in Patients With Stage II-IIIB Squamous-cell Carcinoma of the Anal CanalTerminatedNCT01843452Phase 2
- High Dose Therapy and Autologous Stem Cell Transplantation Followed by Infusion of Chimeric Antigen Receptor (CAR) Modified T-Cells Directed Against CD19+ B-Cells for Relapsed and Refractory Aggressive B Cell Non-Hodgkin LymphomaActive, not recruitingNCT01840566Phase 1
- High-dose Cyclophosphamide for Severe Refractory Crohn DiseaseWithdrawnNCT01836289Phase 1/2
- Low-dose Cyclophosphamide and Outpatient IV Interleukin-2 in Metastatic MelanomaWithdrawnNCT01833767Phase 2
- BR in Patients With CLL With Comorbidities and/or Renal DysfunctionCompletedNCT01832922Phase 1
- A Phase III Study of Re-Irradiation in Recurrent GlioblastomaWithdrawnNCT01830101Phase 3
- ICARuS Post-operative Intraperitoneal Chemotherapy (EPIC) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) After Optimal Cytoreductive Surgery (CRS) for Neoplasms of the Appendix, Colon or Rectum With Isolated Peritoneal MetastasisActive, not recruitingNCT01815359Phase 2
- Phase II Study of Chlorambucil and Subcutaneous Rituximab in Patients With Extranodal MALT LymphomaActive, not recruitingNCT01808599Phase 2
- Pomalidomide With Melphalan and Dexamethasone for Untreated Systemic AL AmyloidosisTerminatedNCT01807286Phase 1
- NY-ESO-1 T Cells in OG CancerTerminatedNCT01795976Phase 2
- Whole-Body Radiation Therapy, Systemic Chemotherapy, and High-Dose Chemotherapy Followed By Stem Cell Rescue in Treating Patients With Poor-Risk Ewing SarcomaWithdrawnNCT01795430Not applicable
- First Line Treatment Trial in Multiple Myeloma, Finnish Myeloma Group- Multiple Myeloma 02CompletedNCT01790737Phase 2
- A Study of Improving the Efficacy of Treatment in High Risk T Cell Lymphoma PatientsStatus unknownNCT01788137Phase 3
- Efficacy of First Line DRC +/- Bortezomib for Patients With Waldenström's MacroglobulinemiaCompletedNCT01788020Phase 3