Drug
Actinium-225 clinical trials
- studies test it
- 12
- open now
- 9
- in phase 3
- 1
- first study started
- 2019
Keep track of what changes. Save the Actinium-225 studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
12 studies that test it; most in 2026 (7)
| Year | Studies |
|---|---|
| 2019 | 1 |
| 2024 | 2 |
| 2025 | 2 |
| 2026 | 7 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 11
- Phase 2
- 2
- Phase 3
- 1
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 9 · Other 3
Aktis Oncology, Inc. (3) · Alpha-9 Oncology USA Inc. (2) · Peking University Cancer Hospital & Institute (2) · Eli Lilly and Company (1) · AstraZeneca (1) · Full-Life Technologies UK Limited (1) · University College, London (1) · Fusion Pharmaceuticals Inc. (1)
Often tested with
Tested in the same studies.
Studies
Open first, then newest update. How each study uses Actinium-225 is read from its arms, and is right about nine times in ten.
Testing it · 12
- A Study of [225Ac]Ac-AKY-2519 in Patients With B7-H3 Expressing Solid TumorsRecruitingPhase 1Aktis Oncology, Inc.NCT07887971Written as [225Ac]Ac-AKY-2519 (therapeutic)
- AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)RecruitingPhase 3AstraZenecaNCT07611110Written as Actinium (225Ac) zadavotide guraxetan (AZD2265 [FPI-2265])
- SumMET: Study of [225Ac]Ac-FL-261 in Participants With Solid Tumors Overexpressing c-METRecruitingPhase 1/2Full-Life Technologies UK LimitedNCT07873450Written as [225Ac]Ac-FL-261
- A Study of [225Ac]Ac-AKY-1189 in Patients With Solid TumorsRecruitingPhase 1Aktis Oncology, Inc.NCT07020117Written as [225Ac]Ac-AKY-1189 (therapeutic)
- A Study of [225Ac]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate CancerRecruitingPhase 1Aktis Oncology, Inc.NCT07581184Written as [225Ac]Ac-AKY-2519 (therapeutic)
- A Study of [177Lu]Lu-A9-0631 and [225Ac]Ac-A9-0642 With [68Ga]Ga-A9-6217 or [177Lu]Lu-A9-0631 Imaging in GRPR+ Solid TumorsRecruitingPhase 1Alpha-9 Oncology USA Inc.NCT07661641Written as [225Ac]Ac-A9-0642
- ACTinium in Castrate-RESistant Prostate Cancer After LUTEtiumRecruitingPhase 1/2University College, LondonNCT07414940Written as Actinium (225Ac) rhPSMA-10.1
- A Phase I Study to Evaluate the Safety and Preliminary Efficacy of [225Ac]Ac-DOTATATE Injection Combined With Tislelizumab in the Maintenance Treatment Period for Patients of Extensive-stage Small Cell Lung Cancer (ES-SCLC) With Somatostatin Receptors (SSTR)+ as First-line TreatmentRecruitingPhase 1Peking University Cancer Hospital & InstituteNCT07413042Written as [225Ac]Ac-DOTATATE
- A Phase I Study to Assess the Safety and Efficacy of [225Ac]Ac-DOTATATE in Patients With SSTR+ GEP-NensRecruitingPhase 1Peking University Cancer Hospital & InstituteNCT06732505Written as [225Ac]Ac-DOTATATE
- [Ac-225]-PSMA-62 Trial in Oligometastatic Hormone Sensitive and Metastatic Castration Resistant Prostate CancerActive, not recruitingPhase 1Eli Lilly and CompanyNCT06229366Written as [Ac-225]-PSMA-62 (mCRPC)
- A Phase 1-1b Study to Evaluate the Safety, Efficacy and Dosimetry of Study Drug A9-3408 in Subjects With Metastatic MelanomaTerminatedPhase 1Alpha-9 Oncology USA Inc.NCT07076550Written as [225Ac]Ac-A9-3408
- A Phase 1 Study of [225Ac]-FPI-1434 InjectionTerminatedPhase 1Fusion Pharmaceuticals Inc.NCT03746431Written as [225Ac]-FPI-1434 Injection multi-dose