Vaginal Neoplasms clinical trials
The registry lists 159 studies for Vaginal Neoplasms across more than 10 countries. 39 are recruiting or about to start. 10 of them are mainly about Vaginal Neoplasms (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
M.D. Anderson Cancer Center (11) · Merck Sharp & Dohme LLC (10) · National Cancer Institute (NCI) (10) · Shanghai Bovax Biotechnology Co., Ltd. (7) · Ohio State University Comprehensive Cancer Center (6) · Memorial Sloan Kettering Cancer Center (5) · Royal Marsden NHS Foundation Trust (5) · City of Hope Medical Center (4)
What is being tested here
Drugs under test in Vaginal Neoplasms studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Immune checkpoint inhibitors 1 open · Antimetabolites 5 · Angiogenesis inhibitors 4 · Antimitotic agents 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Sep 2027Evaluate the Efficacy, Immunogenicity and Safety of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females · Phase 3 · Shanghai Bovax Biotechnology Co., Ltd.
- Nov 2026Exploring the Effects of Hand and Foot Exercise Intervention in Older Adults With Gynecological Cancer Receiving Chemotherapy Improvement of Peripheral Neuropathy and Quality of Life · Taipei Veterans General Hospital, Taiwan
- Dec 2026Phase 1/2 Study of Autologous SCG142 TCR T Cells in Patients With HPV16/52-positive Carcinoma · SCG Cell Therapy Pte. Ltd.
- Dec 2026Using Reiki Therapy to Improve Symptoms Associated With Brachytherapy in Patients With Gynecological Malignancies · University of Utah
- Dec 2026Image-Guided Gynecologic Brachytherapy · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- Dec 2026Belzutifan in Recurrent Clear Cell Carcinoma of Gynecologic Origin · Dana-Farber Cancer Institute
- Dec 2026Vaginal DHEA to Improve Vaginal Health After Radiation for Women With Gynecologic, Anal or Rectal Cancer · Ohio State University Comprehensive Cancer Center
- Jan 2027e-Health Intervention (Day-by-Day) for the Management of Fear of Progression in Women With Stage III or IV Gynecologic Cancer: A Pilot Study · City of Hope Medical Center
- Jan 2027E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers · Christian Hinrichs
- Mar 2027A Single-arm, Multicenter Clinical Study of Becotatug Vedotin Combined With Zimberelimab in the Treatment of Recurrent and Metastatic Cervical Cancer, Vulvar Cancer and Vaginal Cancer · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Who these studies take
Of the 34 Vaginal Neoplasms studies recruiting now, 20 (59%) set no upper age limit and 9 (26%) stop at 75 or younger. 5 (15%) take children under 18. 23 (68%) are for women only and 0 (0%) for men only; 6 (18%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (15%) | 1 (3%) |
| 18 | 31 (91%) | 10 (29%) |
| 30 | 32 (94%) | 11 (32%) |
| 40 | 32 (94%) | 11 (32%) |
| 50 | 30 (88%) | 11 (32%) |
| 65 | 29 (85%) | 11 (32%) |
| 75 | 28 (82%) | 10 (29%) |
| 85 | 23 (68%) | 9 (26%) |
Across all 159 studies, recruiting or not: 22% stop at 75 or younger and 17% at 65; 19% take children; 66% are for women only and 0% for men only; 17% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Vaginal Neoplasms studies take
Of 13 phase 3 interventional studies under Vaginal Neoplasms, half reached primary completion within 20 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 3 | 20 mo15–26 · 13 studies | — | — |
| Interventional, no phase | 27 mo18–82 · 22 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered2
- Methylation Profiling in Self-Samples for Identification of (Epi)Genetic Biomarkers for Gynecological CancersOct 28, 2026NCT07902375
- Radiotherapy for Gynecologic Cancer With Up to 10 Active Metastatic LesionsOct 20, 2026NCT07883798
Studies
Recruiting first, then most recently updated. Showing 50 of 159. Browse all 159 → or search them.
- Methylation Profiling in Self-Samples for Identification of (Epi)Genetic Biomarkers for Gynecological CancersRecruitingNCT07902375Not applicable1 country
- E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated CancersRecruitingNCT05686226Phase 21 country
- E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated CancersRecruitingNCT05639972Phase 1/21 country
- Radiotherapy for Gynecologic Cancer With Up to 10 Active Metastatic LesionsRecruitingNCT078837981 country
- Reirradiation and Total Ablative Strategies for Recurrent Gynecologic CancerRecruitingNCT076671921 country
- A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast CancerRecruitingNCT07741968Not applicable1 country
- Using Reiki Therapy to Improve Symptoms Associated With Brachytherapy in Patients With Gynecological MalignanciesRecruitingNCT05979610Phase 21 country
- DESTINY-PANTUMOUR04RecruitingNCT071240001 country
- Vagina-View Safety and Imaging FeasibilityRecruitingNCT07818850Not applicable1 country
- Integrated Cancer Repository for Cancer ResearchRecruitingNCT020126991 country
- A Single-arm, Multicenter Clinical Study of Becotatug Vedotin Combined With Zimberelimab in the Treatment of Recurrent and Metastatic Cervical Cancer, Vulvar Cancer and Vaginal CancerRecruitingNCT07424664Phase 21 country
- Quality of Life and Sexuality After Pelvic Exenteration for Gynecologic CancerEnrolling by invitationNCT075943271 country
- Vaginal DHEA to Improve Vaginal Health After Radiation for Women With Gynecologic, Anal or Rectal CancerRecruitingNCT07407647Phase 21 country
- Assessment of Sexual Quality of Life Following Local Treatment (Radiotherapy With or Without Surgery) in Patients With HPV-positive Pelvic Cancer: a Descriptive Longitudinal StudyNot yet recruitingNCT07523152Not applicable
- Talazoparib and Radiation Therapy in Treating Patients With Locally Recurrent Gynecologic CancersRecruitingNCT03968406Phase 11 country
- 3D Printed Custom Applicators for HDR BT (DISCO)RecruitingNCT06432478Not applicable1 country
- Clinical Outcomes and Quality of Life in Patients With Locally Advanced Vulvovaginal Cancers: Ambispective Registration Study.RecruitingNCT071797571 country
- Exploring the Effects of Hand and Foot Exercise Intervention in Older Adults With Gynecological Cancer Receiving Chemotherapy Improvement of Peripheral Neuropathy and Quality of LifeNot yet recruitingNCT07362147Not applicable1 country
- Image-Guided Gynecologic BrachytherapyRecruitingNCT02993900Not applicable1 country
- Belzutifan in Recurrent Clear Cell Carcinoma of Gynecologic OriginRecruitingNCT06677190Phase 21 country
- Image-guided Brachytherapy for Vaginal Cancer (EMBRAVE)RecruitingNCT065142351 country
- Radiochemotherapy and Interventional Radiotherapy in Vaginal CancerRecruitingNCT063145681 country
- Minimally Invasive Pelvic Exenteration in Vaginal or Cervical Cancer RecurrenceRecruitingNCT06867445Not applicable1 country
- NYSCF Scientific Discovery BiobankRecruitingNCT062031061 country
- Specimen and Data Study for Ovarian Cancer Early Detection and PreventionRecruitingNCT000050951 country
- A Phase II, Single-arm, Multicenter, Prospective Study of Cardunolizumab in Recurrent or Metastatic Vulvar and Vaginal CancerRecruitingNCT06292689Phase 21 country
- HPV Vaccine, Imiquimod, and Metformin Combination TrialRecruitingNCT06686043Phase 21 country
- The Gynecological Cancer Associated Thrombosis (GynCAT) StudyRecruitingNCT062843431 country
- SCG142 TCR-T Cells for Human Papillomavirus-Associated CarcinomasRecruitingNCT06544720Phase 11 country
- Phase 1/2 Study of Autologous SCG142 TCR T Cells in Patients With HPV16/52-positive CarcinomaNot yet recruitingNCT06505551Phase 1/2
- Evaluate the Efficacy, Immunogenicity and Safety of 9-valent HPV Recombinant Vaccine in Chinese Healthy FemalesRecruitingNCT04422366Phase 31 country
- Interventions for the Management of Perineal Cancer PainNot yet recruitingNCT06392399Not applicable
- Immunobridging Study of 9-valent Human Papillomavirus Recombinant Vaccine in Chinese Females Aged 9 to 19 YearsRecruitingNCT04895020Phase 31 country
- Immunogenicity and Safety of Quadrivalent HPV Vaccine in Healthy Chinese Female Subjects Aged 9 to 19 YearsRecruitingNCT05027776Phase 31 country
- Immune Persistence After the Whole Vaccination Shcedule With Recombination Quadrivalent HPV VaccineRecruitingNCT053713531 country
- HRYZ-T101 TCR-T Cell for HPV-18 Positive Advanced Solid TumorRecruitingNCT05787535Phase 11 country
- HRYZ-T101 Injection for HPV18 Positive Solid TumorRecruitingNCT05952947Phase 11 country
- Peritoneum Vaginoplasty; Implementation According to IDEAL FrameworkRecruitingNCT05925361Not applicable1 country
- Retrospective Study of BrachytherapyRecruitingNCT052428611 country
- e-Health Intervention (Day-by-Day) for the Management of Fear of Progression in Women With Stage III or IV Gynecologic Cancer: A Pilot StudyActive, not recruitingNCT05786456Not applicable1 country
- A Three-arm Randomized Phase II Study of Dostarlimab Alone or With Bevacizumab Versus Nonplatinum Chemotherapy in Recurrent Gynecological Clear Cell Carcinoma: DOVE (APGOT-OV7/ ENGOT-ov80 Study)Active, not recruitingNCT06023862Phase 27 countries
- Testing the Addition of a New Anti-Cancer Drug, Triapine, to the Usual Chemotherapy Treatment (Cisplatin) During Radiation Therapy for Advanced-stage Cervical and Vaginal CancersActive, not recruitingNCT02466971Phase 33 countries
- Peer-to-Peer Support Program in Improving Quality of Life Outcomes in Patients With Gynecologic Cancer and Their CaregiversTerminatedNCT02412124Not applicable1 country
- Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic CancersActive, not recruitingNCT07118176Phase 11 country
- Physical Activity Intervention Among Older Women With Gynecologic Cancers (Fit4Treatment)Active, not recruitingNCT05743517Not applicable1 country
- Agnostic Therapy in Rare Solid TumorsActive, not recruitingNCT06638931Phase 21 country
- A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon CancersCompletedNCT04708470Phase 1/21 country
- MRI-Guided Brachytherapy in Treating Participants With HPV-Associated Stage IB2-IVA Cervical or Stage II-IVA Vaginal CancerTerminatedNCT03634267Phase 11 country
- Longitudinal Evaluation of Women Undergoing Pelvic Surgery for the Treatment of Gynecologic CancerActive, not recruitingNCT007916351 country
- ASk Questions in GYnecologic Oncology (ASQ-GYO)CompletedNCT06339827Not applicable1 country