Retinal Degeneration: all 132 studies
Page 1 of 2. Open to participants first (23), then studies with results posted, then the rest; newest registration first within each.
- Monitoring and Early Detection of Treatable Inherited RETinal Disease in Children and AdolescentsRecruitingNCT07901907
- Retinal and Choroidal Changes in Periodontal DiseaseNot yet recruitingNCT07856901
- Open-Label Study to Evaluate the Safety, Tolerability, and Efficacy of Gene Therapy (SPVN20) in Subjects With Rod-Cone DystrophyRecruitingNCT07807111Phase 1/2
- Observational Study to Investigate the Short-term Effects of Transcorneal Electrical Stimulation on Visual PerformanceRecruitingNCT07548944
- Multicenter Study of Transcranial Magnetic Stimulation on Vision RestorationNot yet recruitingNCT07425717Not applicable
- First-in-Human, Dose Escalation Trial of AXV-101 in BBS1-Related Retinal DegenerationRecruitingNCT07269665Early Phase 1
- Inherited Retinal Diseases: Natural History and Genotype-Phenotype CorrelationsNot yet recruitingNCT07265895
- SGLT2 Inhibitors in Geographic AtrophyRecruitingNCT07174687Phase 2
- Safety and Preliminary Efficacy of VG801 in Patients With ABCA4 Mutation-associated Retinal Dystrophy (Stargardt Disease)RecruitingNCT07002398Phase 1/2
- A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)RecruitingNCT06789445Phase 1/2
- Biomarkers in Retinitis PigmentosaRecruitingNCT06306690
- A Study Comparing Two Doses of AGTC-501 in Male Participants With X-linked Retinitis Pigmentosa Caused by RPGR Mutations (DAWN)Enrolling by invitationNCT06275620Phase 2
- Validation of Questionnaire in Retinal DegenerationNot yet recruitingNCT06185517Not applicable
- Retinal Atrophy and Neurofilament Light Chain in People With Multiple Sclerosis Taking OfatumumabEnrolling by invitationNCT06167642
- A Long-Term Follow-Up Study in Subjects Who Received vMCO-I Administered Via Intravitreal InjectionEnrolling by invitationNCT05921162
- Safety and Tolerability Subretinal OPGx-001 for LCA5-Associated Inherited Retinal Degeneration (LCA5-IRD) and Non-interventional Arm With Untreated PatientsRecruitingNCT05616793Phase 1/2
- ORACLE: A Long-term Follow-up Study to Evaluate the Safety of GT005 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration Treated in a Gyroscope-sponsored Antecedent StudyEnrolling by invitationNCT05481827Phase 2
- Minocycline for Chronic Autoimmune UveitisRecruitingNCT05474729Phase 1/2
- Adaptive Optics Imaging of Outer Retinal DiseasesRecruitingNCT05355415
- High Resolution, High-speed Multimodal Ophthalmic ImagingRecruitingNCT04129021Not applicable
- Rod and Cone Mediated Function in Retinal DiseaseRecruitingNCT02617966
- High Resolution Retinal ImagingRecruitingNCT01866371
- Cell Collection to Study Eye DiseasesRecruitingNCT01432847
- Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With DME (ASPIRE)CompletedNCT06011798Phase 2Results posted
- Suprachoroidal Sustained-Release OXU-001 Compared to Intravitreal Ozurdex® in the Treatment of Diabetic Macular EdemaCompletedNCT05697809Phase 2Results posted
- A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 in Non-proliferative Diabetic Retinopathy (NPDR)TerminatedNCT05066230Phase 3Results posted
- A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 Compared With Intravitreal Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD)CompletedNCT04964089Phase 3Results posted
- OPT-302 With Aflibercept in Neovascular Age-related Macular Degeneration (nAMD)TerminatedNCT04757636Phase 3Results posted
- Safety and Bioactivity of AXT107 in Subjects With Diabetic Macular EdemaTerminatedNCT04697758Phase 1/2Results posted
- A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Neovascular Age-related Macular DegenerationTerminatedNCT04684394Phase 2Results posted
- Efficacy and Safety of Two Different Brolucizumab 6 mg Dosing Regimens in Neovascular Age-related Macular DegenerationCompletedNCT04679935Phase 4Results posted
- A Trial to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Participants With Diabetic Macular Edema (DME)TerminatedNCT04611152Phase 3Results posted
- A Study to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Participants With Diabetic Macular Edema (DME)TerminatedNCT04603937Phase 3Results posted
- A Study to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Patients With Macular Edema Due to Retinal Vein Occlusion (RVO)CompletedNCT04592419Phase 3Results posted
- HORIZON: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005TerminatedNCT04566445Phase 2Results posted
- EXPLORE: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005TerminatedNCT04437368Phase 2Results posted
- A Study to Assess the Efficacy and Safety of AKST4290 With Aflibercept in Patients With Newly Diagnosed nAMDCompletedNCT04331730Phase 2Results posted
- A Study to Evaluate the Efficacy and Safety of KSI-301, an Anti-VEGF Antibody Biopolymer Conjugate, Versus Aflibercept in Patients With Neovascular (Wet) Age-Related Macular Degeneration.TerminatedNCT04049266Phase 2/3Results posted
- Study to Assess the Efficacy and Safety of Brolucizumab 6mg Compared to Aflibercept 2 mg in a Treat-to-control Regimen (TALON)CompletedNCT04005352Phase 3Results posted
- Study to Collect Safety and ECG Data on Brolucizumab 6 mg Intravitreal Treatment in Patients With Wet AMDCompletedNCT03954626Phase 3Results posted
- FOCUS: A Phase I/II First in Human Study to Evaluate the Safety and Efficacy of GT005 Administered in Subjects With Dry AMDTerminatedNCT03846193Phase 1/2Results posted
- Changes of Macular Pigment and Parameters of Eyes After YAG Laser Treatment in Cases With Capsule OpacificationCompletedNCT03321253Not applicableResults posted
- BCI and Evaluation of Visual and Task Performance in Subjects With Eye DiseasesCompletedNCT03318549Not applicableResults posted
- Bridging Animal and Human Models of Exercise-induced Visual RehabilitationActive, not recruitingNCT02911805Not applicableResults posted
- EAGLE: Evaluating Genotypes Using Intravitreal Aflibercept InjectionCompletedNCT02689518Phase 4Results posted
- Safety and Efficacy of rAAV-hRS1 in Patients With X-linked Retinoschisis (XLRS)CompletedNCT02416622Phase 1/2Results posted
- X-82 to Treat Age-related Macular DegenerationTerminatedNCT02348359Phase 2Results posted
- Intravitreal Mesenchymal Stem Cell Transplantation in Advanced Glaucoma.CompletedNCT02330978Phase 1Results posted
- Aflibercept After Ranibizumab in Exudative Age-related Macular DegenerationCompletedNCT02157077Phase 3Results posted
- A Natural History of the Progression of Stargardt Disease: Retrospective and Prospective StudiesCompletedNCT01977846Results posted
- Extension Study to Compare Long-term Efficacy and Safety of Ranibizumab Intravitreal Injections Versus Dexamethasone Intravitreal Implant in Patients With RVOCompletedNCT01580020Phase 4Results posted
- A Study of Intravitreal Injections of 2.0mg Ranibizumab in Subjects With Chronic Fluid On OCT Post Multiple Injections With Ranibizumab (Super-dose Anti-VEgf SAVE Trial)TerminatedNCT01025232Phase 1/2Results posted
- Safety And Tolerability Study Of RN6G In Subjects With Advanced Dry, Age-Related Macular Degeneration Including Geographic AtrophyCompletedNCT01003691Phase 1Results posted
- Safety And Tolerability Study Of RN6G In Patients With Dry, Age-Related Macular DegenerationCompletedNCT00877032Phase 1Results posted
- A Multi-Center Study of Reading Rehabilitation in Macular DiseaseCompletedNCT00746668Not applicableResults posted
- Treatment of Cystoid Macular Edema in Patients With Retinal DegenerationCompletedNCT00716586Phase 4Results posted
- Intravitreal Adalimumab in Inherited and Degenerative Retinal DiseasesActive, not recruitingNCT07348588Phase 1/2
- A Phase 2 Open-label Study to Evaluate the Safety of Laruparetigene Zovaparvovec Administered Bilaterally in Male Participants With X-Linked Retinitis PigmentosaActive, not recruitingNCT07174726Phase 2
- A Repeat-Dose, Open-Label, Two Arm Safety and Efficacy Study of Two Doses of VP-001 Administered Intravitreally in Participants With Confirmed PRPF31 Mutation-Associated Retinal Dystrophy, Including Participants Previously Treated With VP001Active, not recruitingNCT06852963Phase 1/2
- MAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (Wallaby)CompletedNCT06455826Phase 1
- A Study Comparing Two Doses of AGTC-501 in Male Subjects With X-linked Retinitis Pigmentosa Caused by RPGR Mutations (SKYLINE)Active, not recruitingNCT06333249Phase 2
- Natural History Study in Patients With PDE6A-, PDE6B- and RHO-linked Retinitis PigmentosaActive, not recruitingNCT06323772
- A Efficacy and Safety Study of Ranibizumab 10mg/ml Injection (Incepta) in Patients With Diabetic Macular EdemaCompletedNCT06305416Phase 3
- Safety and Efficacy Study of IVB102 Injection in Subjects With X-linked RetinoschisisActive, not recruitingNCT06289452Early Phase 1
- A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Diabetic Retinopathy (DR)CompletedNCT06270836Phase 3
- Non-Interventional Long Term Follow-up Study of Participants Previously Enrolled in the RESTORE StudyActive, not recruitingNCT06162585
- Non-interventional Long Term Follow-up Study of Participants Previously Enrolled in the STARLIGHT StudyActive, not recruitingNCT06048185
- NG101 AAV Gene Therapy in Subjects With Wet Age-Related Macular DegenerationActive, not recruitingNCT05984927Phase 1/2
- Observational Study to Assess the Reliability and Validity of the MLYMT and MLSDTCompletedNCT05820100
- Investigating Geographic Atrophy Insights (i-GAIN) Natural History StudyCompletedNCT05797896
- Promising ROd-cone DYstrophy Gene therapYActive, not recruitingNCT05748873Phase 1/2
- Safety and Effects of a Single Intravitreal Injection of vMCO-010 Optogenetic Therapy in Subjects With Stargardt DiseaseCompletedNCT05417126Phase 2
- Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMDActive, not recruitingNCT05407636Phase 3
- Pistachios and Neural Macular PigmentStatus unknownNCT05283941Not applicable
- Clinical Study to Compare Efficacy and Safety of AVT06 and EU-Eylea (ALVOEYE)CompletedNCT05155293Phase 3
- Efficacy and Safety of MCO-010 Optogenetic Therapy in Adults With Retinitis Pigmentosa [RESTORE]CompletedNCT04945772Phase 2
- Phase 1 Study of Intravitreal Autologous CD34+ Stem Cell Therapy for Retinitis PigmentosaCompletedNCT04925687Phase 1
- Dose-Escalation Study to Evaluate the Safety and Tolerability of Intravitreal vMCO-I in Patients With Advanced Retinitis PigmentosaCompletedNCT04919473Phase 1/2
- An Open-label, Dose Escalation and Double-masked, Randomized, Controlled Trial Evaluating Safety and Tolerability of Sepofarsen in Children (<8 Years of Age) With LCA10 Caused by Mutations in the CEP290 Gene.Status unknownNCT04855045Phase 2/3
- A Clinical Trial Evaluating the Safety and Efficacy of a Single Subretinal Injection of AGTC-501 in Participants With XLRPActive, not recruitingNCT04850118Phase 2/3
- Evaluation of R:GEN as Intervention in Subjects With Early Stages of AMD for Safety and Exploratory Efficacy OutcomesCompletedNCT04776031Not applicable
- Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1FActive, not recruitingNCT04765345
- Pivotal 1 Study of ABBV-RGX-314 (Also Known as RGX-314) Gene Therapy Administered Via Subretinal Delivery One Time in Participants With nAMDActive, not recruitingNCT04704921Phase 2/3
- Long-term Study of ADVM-022 in Neovascular (Wet) AMD [OPTIC-EXT]Active, not recruitingNCT04645212
- A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Dry Age-related Macular DegenerationTerminatedNCT04643886Phase 2
- Bimodal and Coaxial High Resolution Ophtalmic ImagingStatus unknownNCT04620876Not applicable
- Oral Metformin for Treatment of ABCA4 RetinopathyActive, not recruitingNCT04545736Phase 1/2
- NR600 System Retinal Prosthesis for Patients With Retinal Degenerative DiseasesTerminatedNCT04295304Not applicable
- CNS10-NPC for the Treatment of RPActive, not recruitingNCT04284293Phase 1
- First in Human Study to Evaluate the Safety and Tolerability of GEM103 in Geographic Atrophy Secondary to Dry Age Related Macular DegenerationCompletedNCT04246866Phase 1
- Clinical Research of Human Retinal Pigment Epithelial (HuRPE) Cell Injection on Atrophy of High Myopia Macular AreaStatus unknownNCT04212624Not applicable
- High Resolution Retina ImagingStatus unknownNCT04128150
- Evaluation of Discomfort Associated With Scleral Depression During Retina ExaminationsCompletedNCT04115917Not applicable
- Visual Rehabilitation Through Acoustic Biofeedback With Retimax Vision Trainer in Patients With Advanced Age-related Macular DegenerationCompletedNCT04084587Not applicable
- GTSCOPE - To Evaluate the Natural Progression of Dry Age-related Macular Degeneration (AMD)TerminatedNCT03894020
- Single Ascending Dose Study in Participants With LCA10Status unknownNCT03872479Phase 1/2
- Dual Wavelength OCTCompletedNCT03843840
- Stem Cells Therapy in Degenerative Diseases of the RetinaStatus unknownNCT03772938Phase 1
- Assessment of Visual Function With a Portable Brain-computer InterfaceStatus unknownNCT03760055
- ADVM-022 Intravitreal Gene Therapy for Wet AMDCompletedNCT03748784Phase 1