Recurrent respiratory papillomatosis clinical trials
The registry lists 31 studies for Recurrent respiratory papillomatosis across 6 countries. 9 are recruiting or about to start. 26 of them are mainly about Recurrent respiratory papillomatosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-13.
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Who runs them
National Cancer Institute (NCI) (3) · Massachusetts General Hospital (3) · Precigen, Inc (3) · Massachusetts Eye and Ear Infirmary (3) · University Hospital Ostrava (2) · Ruth Tachezy, PhD. (1) · Sanford Health (1) · University of Missouri-Columbia (1)
What is being tested here
Drugs under test in Recurrent respiratory papillomatosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Immune checkpoint inhibitors 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The study
Who these studies take
Of the 6 Recurrent respiratory papillomatosis studies recruiting now, 5 (83%) set no upper age limit and 0 (0%) stop at 75 or younger. 2 (33%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (33%) | 2 (33%) |
| 18 | 6 (100%) | 6 (100%) |
| 30 | 6 (100%) | 6 (100%) |
| 40 | 6 (100%) | 6 (100%) |
| 50 | 6 (100%) | 6 (100%) |
| 65 | 6 (100%) | 6 (100%) |
| 75 | 6 (100%) | 6 (100%) |
| 85 | 6 (100%) | 6 (100%) |
Across all 31 studies, recruiting or not: 26% stop at 75 or younger and 23% at 65; 48% take children; 0% are for women only and 0% for men only; 0% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 15, 2026.
Newly registered1
- Zopapogene Imadenovec for the Treatment of Recurrent Respiratory Papillomatosis in ChildrenOct 28, 2026NCT07901738
Studies
Recruiting first, then most recently updated. Showing 31 of 31. search them.
- Combination Bevacizumab and PRGN-2012 in Adults With Recurrent Respiratory Papillomatosis (RRP)Not yet recruitingNCT07756840Phase 21 country
- Zopapogene Imadenovec for the Treatment of Recurrent Respiratory Papillomatosis in ChildrenNot yet recruitingNCT07901738Phase 31 country
- Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at SanfordRecruitingNCT017931681 country
- Efficacy of Booster Injection With Gardasil-9 Vaccine on Intersurgical Interval* for Adults With Recurrent Respiratory Papillomatosis*Not yet recruitingNCT07339163Phase 1/21 country
- Autologous Dendritic Cell Vaccine For Recurrent Respiratory Papillomatosis (RRP) PatientsRecruitingNCT07317154Phase 11 country
- Merck IIT: RRP Pembro and LenvatinibRecruitingNCT04645602Phase 21 country
- Zopa Retreatment and Vector Shedding in Adults With RRPRecruitingNCT06538480Phase 41 country
- The Natural History and Biological Study of Pulmonary Recurrent Respiratory Papillomatosis (pRRP)RecruitingNCT064121721 country
- Juvenile Recurrent Respiratory Papillomatosis: Establishment of a French National Cohort (PRR : National Cohort " REPA ")RecruitingNCT060005271 country
- Pembrolizumab for HPV-associated Recurrent Respiratory Papilloma PatientsCompletedNCT02632344Phase 21 country
- INO-3107 With Electroporation (EP) in Participants With HPV-6- and/or HPV-11-Associated Recurrent Respiratory Papillomatosis (RRP)CompletedNCT04398433Phase 1/21 country
- Adjuvant PRGN-2012 in Adult Patients With Recurrent Respiratory PapillomatosisActive, not recruitingNCT04724980Phase 1/21 country
- M7824 in People With Recurrent Respiratory PapillomatosisCompletedNCT03707587Phase 21 country
- Optiflow vs. Convential Anesthesia During Pediatric Laryngeal Papilloma RemovalWithdrawnNCT05215249Phase 1/2
- Airway Intervention Registry (AIR): Recurrent Respiratory Papillomatosis (RRP)Status unknownNCT034652801 country
- Avelumab for People With Recurrent Respiratory PapillomatosisCompletedNCT02859454Phase 21 country
- Use of Cidofovir for Recurrent Respiratory PapillomatosisCompletedNCT00205374Phase 4
- Recurrent Respiratory Papillomatosis and Extraesophageal RefluxCompletedNCT02592902Not applicable1 country
- Effect of Vaccination in Patients With Recurrent Respiratory PapillomatosisCompletedNCT01375868Phase 31 country
- Study of Celebrex (Celecoxib) in Patients With Recurrent Respiratory PapillomatosisCompletedNCT00571701Phase 21 country
- Therapeutic Treatment With Human Papillomavirus Quadrivalent Vaccine for Recurrent Respiratory PapillomatosisWithdrawnNCT00829608Early Phase 11 country
- Value of Narrow Band Imaging (NBI) Endoscopy in the Early Diagnosis of Laryngeal Cancer and Precancerous LesionsCompletedNCT02217358Not applicable1 country
- Safety Study of EF-022 in Adults With Recurrent Respiratory Papillomatosis (RRP)Status unknownNCT02854761Phase 1
- Bevacizumab Versus Cidofovir for the Treatment of Recurrent Respiratory PapillomatosisStatus unknownNCT02555800Phase 21 country
- Optical Coherence Tomography of the Airway for Lung Cancer or Lung DiseaseWithdrawnNCT007332521 country
- Interventional Cryotherapy for the Eradication of Benign Airway Disease ("ICE the BAD")TerminatedNCT00747461Phase 41 country
- 4-valent HPV Vaccine to Treat Recurrent Respiratory Papillomatosis in ChildrenStatus unknownNCT01995721Phase 31 country
- Propranolol Administration in Pediatric Patients With Recurrent Respiratory PapillomatosisWithdrawnNCT01058317Phase 2/3
- Bevacizumab for Treatment of Recurrent Respiratory Papillomatosis (RRP)CompletedNCT01020747Phase 11 country
- Multi-Center, Randomized Trial of the Pulsed Dye Laser for JORRPCompletedNCT005509141 country
- A Trial Study of SGN-00101 in Treating Pediatric Patients With Recurrent Respiratory PapillomatosisCompletedNCT00038714Phase 21 country