Plaque, Amyloid clinical trials
The registry lists 34 studies for Plaque, Amyloid across more than 10 countries. 10 are recruiting or about to start. 7 of them are mainly about Plaque, Amyloid (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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A study of drug A after surgery for early breast cancer
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
Eli Lilly and Company (4) · Lantheus Biosciences Ltd. (3) · Washington University School of Medicine (3) · United Biomedical (2) · St. Joseph's Hospital and Medical Center, Phoenix (2) · AC Immune SA (1) · University Hospital, Geneva (1) · Tianjin Medical University (1)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The study
- Mar 2027Association of Transcranial Alternating Current Stimulation with Digital Cognitive Training for Cognitive Remediation in Older Adults · Universidade Federal do Rio de Janeiro
Who these studies take
Of the 7 Plaque, Amyloid studies recruiting now, 3 (43%) set no upper age limit and 0 (0%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 5 (71%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 3 (43%) | 3 (43%) |
| 30 | 4 (57%) | 4 (57%) |
| 40 | 5 (71%) | 5 (71%) |
| 50 | 6 (86%) | 6 (86%) |
| 65 | 7 (100%) | 7 (100%) |
| 75 | 7 (100%) | 7 (100%) |
| 85 | 6 (86%) | 6 (86%) |
Across all 34 studies, recruiting or not: 15% stop at 75 or younger and 15% at 65; 0% take children; 0% are for women only and 3% for men only; 68% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting2
Newly registered2
- Efficacy of Two Brushing Regimens in the Reduction of Established Dental Plaque and GingivitisNov 4, 2026NCT07917507
- Postsurgical Pain and Opioid Use in Older Adults: Effects of Mild Cognitive ImpairmentOct 21, 2026NCT07885085
Studies
Recruiting first, then most recently updated. Showing 34 of 34. search them.
- A Master Protocol Studying Multiple Amyloid-Targeting Therapies in Healthy Participants and Participants With Alzheimer's DiseaseRecruitingNCT07787169Phase 13 countries
- A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).RecruitingNCT07602582Phase 33 countries
- A Study of LY4405094 in Healthy Participants and Participants With Alzheimer's DiseaseRecruitingNCT07787182Phase 13 countries
- A Study of LY4560736 in Healthy Participants and Participants With Alzheimer's Disease (AD)Not yet recruitingNCT07843459Phase 13 countries
- Beta Amyloid PET/CT in Various Aβ-Related DiseaseRecruitingNCT067257061 country
- A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)RecruitingNCT05462106Phase 1/23 countries
- Amyloid Lowering for Alzheimer's in Down's With Donanemab InvestigationNot yet recruitingNCT06911944Phase 4
- MCLENA-2: A Phase II Clinical Trial for the Assessment of Lenalidomide in Patients With Mild Cognitive ImpairmentNot yet recruitingNCT06177028Phase 2
- Association of Transcranial Alternating Current Stimulation with Digital Cognitive Training for Cognitive Remediation in Older AdultsRecruitingNCT06733714Not applicable1 country
- The Influence of Vascular Burden, Amyloid Plaque and Tau Protein in Patients With Vascular Cognitive Impairment and Dementia With TauopathyRecruitingNCT04309253Phase 21 country
- Phase III Study of Florbetaben (BAY94-9172) PET Imaging for Detection/Exclusion of Cerebral β-amyloid Compared to HistopathologyCompletedNCT01020838Phase 35 countries
- Phase II Study of Florbetaben (BAY 94-9172) PET Imaging for Detection/Exclusion of Cerebral β-amyloid in Patients With Probable Alzheimer's Disease Compared to Healthy VolunteersCompletedNCT00750282Phase 25 countries
- MCLENA-1: A Clinical Trial for the Assessment of Lenalidomide in Amnestic MCI PatientsCompletedNCT04032626Phase 21 country
- A Biomarker-chip Assay in Preserved Red Blood Cells for the Diagnosis of Alzheimer's DiseaseCompletedNCT073078721 country
- Acute Plasma Abeta Responses to StressCompletedNCT05521919Not applicable1 country
- Cognitive Health in Ageing Register: Investigational, Observational and Trial Studies in Dementia Research: Prospective Readiness Cohort StudyCompletedNCT021143721 country
- Risk Evaluation and Education for Alzheimer's Disease - the Study of Communicating Amyloid Neuroimaging (REVEAL-SCAN)CompletedNCT02959489Not applicable1 country
- Sleep Quality and Amyloid-Beta KineticsCompletedNCT03077620Not applicable1 country
- CLearing Alzheimer's Disease Molecular Pathology Without MedicationsStatus unknownNCT04913454Not applicable
- Amyloid Plaque and Tangle Imaging in Aging and DementiaCompletedNCT003554981 country
- Escitalopram Effects on CSF Amyloid BetaCompletedNCT02161458Phase 41 country
- Modulation of CSF Amyloid-beta Concentrations Via Behavioral Sleep Deprivation and Pharmacological Sleep InductionCompletedNCT02063217Not applicable1 country
- CNS and Plasma Amyloid-Beta Kinetics in Alzheimer's DiseaseCompletedNCT020216821 country
- Cognitive, Morphological and Neurobiological Progressive Aspects in Bipolar Disorders in the Elderly: Toward to a Neurodegenerescence Detection?Status unknownNCT02843906Not applicable1 country
- Efficacy and Safety of Plasma Exchange With 5% Albumin in Beta-amyloid Peptide Clearance in Cerebral Spinal FluidCompletedNCT00742417Phase 22 countries
- A Study to Evaluate the Effect of Bexarotene on Beta-Amyloid and Apolipoprotein E Metabolism in Healthy SubjectsCompletedNCT02061878Phase 11 country
- Amyloïd Load in Elderly Population: Effect of Cognitive ReserveStatus unknownNCT02196116Not applicable1 country
- Predictive and Diagnostic Value of Tau and Beta-amyloid Markers in the Dementia of Parkinson's DiseaseCompletedNCT02243982Early Phase 11 country
- Florbetaben (BAY94-9172) PET (Positron Emission Tomography) Imaging in MCI (Mild Cognitive Impairment) PatientsCompletedNCT01138111Phase 11 country
- Phase 1 and Phase 2 Clinical Trials of SNUBH-NM-333(18F)TerminatedNCT02149017Phase 1/21 country
- Phase II Study of Florbetaben (BAY94-9172) PET Imaging for Detection/Exclusion of Cerebral β-amyloid.CompletedNCT00928304Phase 21 country
- An Open Positron Emission Tomography Study to Assess the Effects of Varying Mass of AZD4694 on Radioligand Binding Parameters in Healthy Volunteers and Patients With Alzheimer's DiseaseCompletedNCT01325402Phase 11 country
- Study to Evaluate Safety, Tolerability and Immunogenicity of Vaccine (UB 311) in Subjects With Alzheimer's DiseaseCompletedNCT00965588Phase 11 country
- Observational Study to Monitor Long-term Immunogenicity and Efficacy of UB 311 Vaccine in Subjects With Alzheimer's DiseaseCompletedNCT011890841 country