Neurofibromatosis 1: all 221 studies
Page 2 of 3. Open to participants first (44), then studies with results posted, then the rest; newest registration first within each.
- US Selumetinib RegistryTerminatedNCT05683678
- Multi-parametric Biomarker Development to Predict Malignant Conversion in Patients With Neurofibromatosis Type 1Active, not recruitingNCT05677594
- Natural History Study of Cutaneous Neurofibromas in People With NF1Active, not recruitingNCT05581511
- PASS of Paediatric Patients Initiating SelumetinibActive, not recruitingNCT05388370
- Intervention Effectiveness on the Neurocognitive Functioning of Children and Adolescents With Neurofibromatosis Type 1CompletedNCT05377008Not applicable
- NF-1, Nutraceutical InterventionActive, not recruitingNCT05363267Phase 1
- Clinical Hypnosis and Home Blood Pressure Monitoring in Children With Neurofibromatosis Type 1CompletedNCT05196854Not applicable
- Molecular Aspects of Preimplantation Genetic Diagnosis for NF1CompletedNCT05149469
- A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of TQ-B3234 in Patients With Type I NeurofibromatosisStatus unknownNCT05107037Phase 1
- Phase I Study to Assess the Effect of Food on the PK and Gastrointestinal Tolerability of Selumetinib in Adolescent Children With Neurofibromatosis Type 1 Related Plexiform NeurofibromasActive, not recruitingNCT05101148Phase 1
- A Clinical Trial to Evaluate the Safety and Efficacy of AL2846 Capsules in Chinese Patients With Type I NeurofibromatosisTerminatedNCT05011019Phase 1/2
- Mechanism of Action of Transcranial Direct Current Stimulation in Neurofibromatosis Type 1CompletedNCT04991428Not applicable
- Study to Evaluate the Safety, Tolerability, PK Characteristics and Anti-tumor Activity of FCN-159 in Adult and Pediatric Participants With Neurofibromatosis Type 1Active, not recruitingNCT04954001Phase 1/2
- Evaluating Genetic Modifiers of Cutaneous Neurofibromas in Adults With Neurofibromatosis Type 1CompletedNCT04941027
- Systematically Assessing Changes in Plexiform Neurofibroma Related Disfigurement From Photographs of Subjects With Neurofibromatosis Type 1 on a Phase 2 Clinical TrialCompletedNCT04879160
- Pilot Randomized Control Trial of Telehealth Group for Improving Peer Relationships (PEERS) in NF1Status unknownNCT04860362Not applicable
- Open Trial of Telehealth Group for Improving Peer Relationships (PEERS) in NF1Status unknownNCT04856514Not applicable
- PF-07284892 in Participants With Advanced Solid TumorsTerminatedNCT04800822Phase 1
- Incidence of Malignant Peripheral Nerve Sheath Tumor (MPNST) Development in Participants With Neurofibromatosis Type 1 (NF1) Receiving and Not Receiving Medical Therapies Directed at Plexiform Neurofibromas (PN)CompletedNCT04774289
- Tolerability of Device Based Therapies for Neurofibromatosis Type 1 Cutaneous NeurofibromasCompletedNCT04730583Phase 1
- A Study of Selumetinib in Chinese Paediatric and Adult Subjects With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN)Active, not recruitingNCT04590235Phase 1
- Selumetinib Paediatric NF1 Japan StudyCompletedNCT04495127Phase 1
- Quality Improvement Project - "My Logbook! - I Know my Way Around!"; ("Mein Logbuch - Ich Kenne Mich Aus!")CompletedNCT04474678Not applicable
- A Long-term Study of NPC-12G Gel in Neurofibromatosis Type ITerminatedNCT04461886Phase 3
- Frameshift Peptides of Children With NF1CompletedNCT04212351
- Function of the Pigment Epithelium in Patients With Type 1 NeurofibromatosisCompletedNCT04153344
- Comparison of Gastrointestinal Motility in Healthy Children and Children With ConstipationStatus unknownNCT03981510Not applicable
- Pediatric Long-Term Follow-up and Rollover StudyActive, not recruitingNCT03975829Phase 4
- Whole-body Vibration in Children With Neurofibromatosis Type 1CompletedNCT03888248Not applicable
- A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade GliomaActive, not recruitingNCT03871257Phase 3
- From Molecules to Cognition: Inhibitory Mechanisms in ASD and NF1CompletedNCT03826940Not applicable
- Whole Body MRI to Identify Atypical Neurofibromas in Patients With NF1Active, not recruitingNCT03820778Not applicable
- Prevalence of Constitutional Mismatch-repair Deficiency Among Suspected Neurofibromatosis Type 1/Legius Syndrome Children Without a Malignancy and Without a NF1 or SPRED1 MutationStatus unknownNCT03757247
- Treatment of NF1-related Plexiform Neurofibroma With TrametinibActive, not recruitingNCT03741101Phase 2
- Study of Imatinib in Children With Neurofibromatosis and Airway TumorsWithdrawnNCT03688568Phase 2
- A Single Center Pilot Study to Assess the Intra-observer Reliability of Measuring Muscle Strength Using a Hand Held Dynamometer in Children and Adults With Neurofibromatosis Type 1 (NF1) and Type 2 (NF2)CompletedNCT03672838Not applicable
- A Study to Evaluate Bioavailability and Food Effect of Selumetinib (AZD6244) in Healthy Male ParticipantsCompletedNCT03649165Phase 1
- Reliability of Functional Outcome Measures in Neurofibromatosis 2CompletedNCT03617276
- Vision, Attention and Reading in Neurofibromatosis Type 1 (NF1) ChildrenStatus unknownNCT03518710Not applicable
- Resiliency Training for Adults With Neurofibromatosis Via Live VideoconferencingCompletedNCT03406208Not applicable
- Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway.Active, not recruitingNCT03363217Phase 2
- Stem Cells in NF1 Patients With Tumors of the Central Nervous SystemWithdrawnNCT03332030
- Intermittent Dosing Of Selumetinib In Childhood NF1 Associated TumoursCompletedNCT03326388Phase 1/2
- Non-invasive Stimulation in Neurofibromatosis Type 1CompletedNCT03310996Not applicable
- Study About Annoucement of the Diagnosis of Neurofibromatosis 1 in de Novo FormsCompletedNCT03298438
- An Intermediate Access Protocol for Selumetinib for Treatment of Neurofibromatosis Type 1Approved for marketingNCT03259633
- WES of NF2-associated in Comparison to Sporadic Vestibular Schwannomas - Correlation With Clinical DataCompletedNCT03210285
- Mitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in People With Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST)WithdrawnNCT03109301Phase 2
- Use of Topical Liquid Diclofenac Following Laser Microporation of Cutaneous Neurofibromas in Patients With NF1CompletedNCT03090971Phase 2
- Interventions for Reading Disabilities in NF1Active, not recruitingNCT02964884Phase 2
- Efficacy of Computerized Cognitive Training and Stimulant Medication in Neurofibromatosis Type 1CompletedNCT02944032Not applicable
- Icotinib Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related TumorsCompletedNCT02934256Phase 2
- Resiliency Training for Patients With NF2 Via Videoconferencing With SkypeCompletedNCT02811718Not applicable
- Targeting the Mechanisms Underlying Cutaneous Neurofibroma Formation in NF1: A Clinical Translational Approach.CompletedNCT02777775
- Photodynamic Therapy for Benign Dermal Neurofibromas- Phase IITerminatedNCT02728388Phase 2
- Vaccine Therapy in Treating Patients with Malignant Peripheral Nerve Sheath Tumor That is Recurrent or Cannot Be Removed by SurgeryCompletedNCT02700230Phase 1
- Analysis of Plasma for Diagnosis and Follow-up of Neurofibromatosis Type 1Status unknownNCT02680431
- Compassionate Use Arm - ABI541 ABI for 10 NF2 PatientsNo longer availableNCT02589912
- Hypotonia and Neurofibromatosis Type 1 (NF1) GliomaTerminatedNCT02584413Not applicable
- Subtle Myocardial Deformation Abnormalities in Asymptomatic Nf-1 PatientsStatus unknownNCT02505412
- Reliability of Functional Outcome Measures in Neurofibromatosis 1CompletedNCT02479360
- The Cognitive Variability in NF1 and TSC Monozygotic TwinsStatus unknownNCT02436746
- Relationship Between Psychosocial Factors, Health Literacy, Quality of Life and Satisfaction With Medical Visits in Adults With NFCompletedNCT02435628
- Functional Imaging and Reading Deficit in Children With NF1CompletedNCT02422732Not applicable
- Pomalidomide in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System TumorsCompletedNCT02415153Phase 1
- MEK 1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform NeurofibromasActive, not recruitingNCT02407405Phase 2
- Reading Disability in Children With NF1CompletedNCT02397967Not applicable
- Resiliency Training for Adolescent Neurofibromatosis Patients Via Videoconferencing With SkypeCompletedNCT02387177Not applicable
- Resiliency Training for Patients With Neurofibromatosis Via Videoconferencing With SkypeCompletedNCT02298270Not applicable
- Effect of Lamotrigine on Cognition in NF1TerminatedNCT02256124Phase 2/3
- Effect of Implant Position on Magnetic Resonance Image DistortionCompletedNCT02246231Not applicable
- Study of Imatinib Mesylate in Neurofibromatosis Type I Patients Aged 2 to 21 With Plexiform NeurofibromasTerminatedNCT02177825Phase 2
- Internet Support Group for Parents of a Child With Neurofibromatosis Type 1CompletedNCT02153931
- Endostatin Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related TumorsCompletedNCT02104323Phase 2
- Ophthalmological Screening and Follow-up of Optic Pathway Gliomas in Children With Neurofibromatosis Type 1.Status unknownNCT02078401
- Vitamin D Supplementation for Adults With Neurofibromatosis Type 1 (NF1)TerminatedNCT01968590Phase 2
- Neuropsychological Impairment and Quality of Life in Neurofibromatosis Type 1CompletedNCT01851135Not applicable
- PET/MRI in CNS and Extra-CNS Tumors of Patients With Neurofibromatosis-1 (NF1)CompletedNCT01800032
- Whole Body Magnetic Resonance Imaging With Diffusion Weighted Imaging : Potential Role in NeurofibromatosisStatus unknownNCT01777451
- Genetic Evaluation of NF1 and Scoliosis PatientsCompletedNCT01776125
- Neurofibromatosis Type 1 Brain Tumor Genetic RiskCompletedNCT01707836
- Relationship Stressors in Parents of Children With Cancer or Neurofibromatosis Type 1 (NF1)CompletedNCT01702922
- Modifying Genes in Neurofibromatosis 1Status unknownNCT01650142
- Validating Pain Scales in Children and Young AdultsCompletedNCT01639950
- Acceptance and Commitment Therapy for Adolescents and Young Adults With Neurofibromatosis and Chronic PainCompletedNCT01633008Early Phase 1
- How Neurofibromatosis Type 1 (NF1) Affects Schoolwork and Self-EsteemStatus unknownNCT01626846
- MicroRNAs in Patients With Neurofibromatosis Type 1CompletedNCT01595139
- Efficacy and Safety Study of RAD001 in the Growth of the Vestibular Schwannoma(s) in Neurofibromatosis 2 (NF2) PatientsCompletedNCT01490476Phase 2
- Analysis of Data Collected From Individuals Administered Neurobehavioral AssessmentsCompletedNCT01445314
- Use of RAD001 as Monotherapy in the Treatment of Neurofibromatosis 1 Related Internal Plexiform NeurofibromasCompletedNCT01412892Phase 2
- Neurofibromatosis Type 1 Patient RegistryCompletedNCT01410006
- AZD6244 Hydrogen Sulfate for Children With Nervous System TumorsActive, not recruitingNCT01362803Phase 1/2
- Study of RAD001 for Treatment of NF2-related Vestibular SchwannomaTerminatedNCT01345136Phase 2
- Using Positron Emission Tomography to Predict Intracranial Tumor Growth in Neurofibromatosis Type II PatientsCompletedNCT01222728
- Microarray CGH Analysis of Circulating Tumoral Plasma DNA in NF1 Patients With MPNSTsStatus unknownNCT01218152
- Analysis of Peripheral Nerve Sheath Tumors (PNSTs) in Neurofibromatosis Type 1 (NF1) PatientsStatus unknownNCT01218139
- Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade GliomaActive, not recruitingNCT01089101Phase 1/2
- Effects of Physical Training on Bone and Muscle Quality, Muscle Strength, and Motor Coordination in Children With NF1CompletedNCT01058330Not applicable
- Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)CompletedNCT01031901Phase 1
- Natural History Study of Patients With Neurofibromatosis Type IActive, not recruitingNCT00924196