Nasopharyngeal Neoplasms clinical trials
The registry lists 226 studies for Nasopharyngeal Neoplasms across more than 10 countries. 42 are recruiting or about to start. 99 of them are mainly about Nasopharyngeal Neoplasms (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Nasopharyngeal Carcinoma too: 861 studies, 301 open.
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Status
Who runs them
Sun Yat-sen University (38) · National Cancer Institute (NCI) (12) · M.D. Anderson Cancer Center (7) · National University Hospital, Singapore (6) · Memorial Sloan Kettering Cancer Center (5) · Chinese University of Hong Kong (4) · Dana-Farber Cancer Institute (4) · Zhejiang Cancer Hospital (4)
What is being tested here
Drugs under test in Nasopharyngeal Neoplasms studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Cisplatin | 2 | 2 | 18 |
| Gemcitabine | 2 | 2 | 9 |
| Toripalimab | 2 | 0 | 4 |
| Camrelizumab | 2 | 2 | 3 |
| Nivolumab | 2 | 0 | 3 |
| Fluorouracil | 1 | 0 | 6 |
| Pembrolizumab | 1 | 1 | 4 |
| Endostar protein | 1 | 0 | 3 |
| Tislelizumab | 1 | 2 | 2 |
| Cemiplimab | 1 | 0 | 1 |
Drug classes tested here Immune checkpoint inhibitors 12 open · Antimetabolites 3 open · Angiogenesis inhibitors 1 open · Tyrosine kinase inhibitors (TKIs) 1 open · Antimitotic agents 16
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Aug 2027Cadonilimab (PD-1/CTLA-4 Bispecific Blockade) and Chemoradiotherapy in Nasopharyngeal Carcinoma (GEMSTONE) · Phase 3 · Sun Yat-sen University
- Dec 2026IMRT Combined With Lobaplatin-based CCRT in Nasopharyngeal Carcinoma · The First Affiliated Hospital of Xiamen University
- Dec 2026AI System for Anatomic Recognition & Lesion Detection in Nasopharyngolaryngoscopy: A Prospective Study · Ruijin Hospital
- Dec 2026Discovery of Biomarkers for Intrinsic Radiation Sensitivity in Cancer Patients · National Cancer Centre, Singapore
- Apr 2027Sensor-Assisted Prevention of Dehydration in Head and Neck Cancer Patients · M.D. Anderson Cancer Center
- May 2027Full-wrap Versus Conventional Suspension for Reducing Soft Palate Injury Rate in Transoral Surgery · Sun Yat-sen University
- Jun 2027EGFR Antibody Combined With PD-1 Inhibitor and Chemotherapy in R/M Nasopharyngeal Carcinoma · Sun Yat-sen University
- Jun 2027The Clinical Application Value of CAIX-Targeted PET Hypoxia Imaging in Malignant Tumors · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
- Sep 2027A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors · Marengo Therapeutics, Inc.
- Sep 2027Atezolizumab and Bevacizumab in Treating Patients With Rare Solid Tumors · M.D. Anderson Cancer Center
Who these studies take
Of the 32 Nasopharyngeal Neoplasms studies recruiting now, 9 (28%) set no upper age limit and 18 (56%) stop at 75 or younger. 3 (9%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (6%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (6%) | 2 (6%) |
| 18 | 28 (88%) | 28 (88%) |
| 30 | 32 (100%) | 32 (100%) |
| 40 | 32 (100%) | 32 (100%) |
| 50 | 32 (100%) | 32 (100%) |
| 65 | 32 (100%) | 32 (100%) |
| 75 | 22 (69%) | 22 (69%) |
| 85 | 14 (44%) | 14 (44%) |
Across all 226 studies, recruiting or not: 39% stop at 75 or younger and 15% at 65; 13% take children; <1% are for women only and 0% for men only; 4% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Nasopharyngeal Neoplasms studies take
Of 33 phase 2 interventional studies under Nasopharyngeal Neoplasms, half reached primary completion within 55 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 55 mo31–124 · 33 studies | — | — |
| Interventional, no phase | 93 mo31–143 · 18 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 15, 2026.
Newly registered1
- The Clinical Application Value of CAIX-Targeted PET Hypoxia Imaging in Malignant TumorsOct 22, 2026NCT07890038
Studies
Recruiting first, then most recently updated. Showing 50 of 226. Browse all 226 → or search them.
- A Study of Cemiplimab and Fianlimab in People With Nasopharyngeal CarcinomaNot yet recruitingNCT07650266Phase 11 country
- Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal VolunteersRecruitingNCT009004191 country
- Dynamic Plasma EBV DNA-Guided Risk-Adapted Treatment With Becotatug Vedotin (MRG003) Plus PD-1 Blockade in Locoregionally Advanced Nasopharyngeal CarcinomaNot yet recruitingNCT07524413Phase 2
- Nivolumab in Nasopharyngeal Cancer With Progression During or After Platinum-based TreatmentRecruitingNCT04875611Phase 21 country
- AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)RecruitingNCT07038343Phase 1/22 countries
- Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid TumorsRecruitingNCT05983432Phase 15 countries
- Intratumoral Injection of Recombinant Human Endostatin Adenovirus (EDS01) for the Treatment of Recurrent or Metastatic Head and Neck TumorsRecruitingNCT07625423Phase 11 country
- A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid TumorsRecruitingNCT05592626Phase 1/24 countries
- A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal CancerRecruitingNCT06457503Phase 42 countries
- Full-wrap Versus Conventional Suspension for Reducing Soft Palate Injury Rate in Transoral SurgeryNot yet recruitingNCT07552545Not applicable1 country
- Integrated Cancer Repository for Cancer ResearchRecruitingNCT020126991 country
- Induction Chemotherapy Response-Guided Radiation for EBV-Associated Nasopharyngeal CarcinomaRecruitingNCT06682442Not applicable1 country
- Trop2-targeted immunoPET Imaging of Solid TumorsRecruitingNCT06851663Phase 2/31 country
- EGFR Antibody Combined With PD-1 Inhibitor and Chemotherapy in R/M Nasopharyngeal CarcinomaRecruitingNCT06802835Phase 1/21 country
- The Head and Neck Registry of the European Reference Network on Rare Adult Solid CancersRecruitingNCT054833743 countries
- PD-1 Inhibitor Plus Chemotherapy Followed by Immediate Versus Selective Re-irradiation for Locally Advanced Recurrent NPCRecruitingNCT07332247Phase 21 country
- Anlotinib Plus Immunotherapy and Chemoradiotherapy for High-Risk Nasopharyngeal CarcinomaNot yet recruitingNCT07385079Phase 3
- Short-course Tislelizumab Combined With Chemoradiotherapy for Nasopharyngeal CarcinomaNot yet recruitingNCT07373990Phase 3
- AI System for Anatomic Recognition & Lesion Detection in Nasopharyngolaryngoscopy: A Prospective StudyRecruitingNCT073263581 country
- Induction High-Low Dose Radiotherapy Plus Anti-PD-1 Followed by Definitive Radiotherapy in Recurrent Nasopharyngeal Carcinoma (Single-Arm Phase II)RecruitingNCT07277764Phase 21 country
- Randomised Trial of Induction Gemcitabine and Cisplatin Versus Gemcitabine, Cisplatin, Pembrolizumab and Bevacizumab (GPPB) in Nasopharyngeal CancerRecruitingNCT05305131Phase 21 country
- IMRT Combined With Lobaplatin-based CCRT in Nasopharyngeal CarcinomaEnrolling by invitationNCT06688175Phase 21 country
- Two-cycle and Three-cycle Induction Therapy With Modified TPF Regimen Combined and Camrelizumab for LANPCRecruitingNCT06811844Phase 21 country
- Discovery of Biomarkers for Intrinsic Radiation Sensitivity in Cancer PatientsRecruitingNCT043400241 country
- QL1706 (PD-1/CTLA-4 Bi-specific Antibody) and Chemoradiotherapy in Locoregionally-advanced Nasopharyngeal Carcinoma.RecruitingNCT06749899Phase 31 country
- JMT101 Combined With Mitoxantrone Liposome for Nasopharyngeal CancerNot yet recruitingNCT06892431Phase 2
- Adebrelimab and Chemoradiotherapy in High-risk LANPCRecruitingNCT06349889Phase 21 country
- ChemoRT With and Without Dental Stent for Taste Protection in NPC PatientsRecruitingNCT06733948Phase 21 country
- Arabic PRO Measures for Head and Neck Cancer Radiotherapy.RecruitingNCT066629291 country
- U87 CAR-T in Patients With Advanced Head and Neck TumorsRecruitingNCT06614686Phase 11 country
- GEP Combined With Radiotherapy in Non-locally Treatable Recurrent NPCNot yet recruitingNCT06611826Phase 2
- A Multicentre Study on Features of the Gut Microbiota of Patients With Critical Chronic Diseases in ChinaRecruitingNCT056382691 country
- Exploratory Study of EBV DNA Titre Clearance Whilst on Proton Beam TherapyNot yet recruitingNCT06480903
- Nivolumab in Children and Adults With Nasopharyngeal CarcinomaRecruitingNCT06019130Phase 21 country
- The Protection of Thyroid Function in IMRT for Nasopharyngeal CarcinomaRecruitingNCT06268600Not applicable1 country
- Combining RT With Immunotherapy and Chemotherapy in Metastatic Nasopharyngeal CarcinomaRecruitingNCT05385926Phase 21 country
- Tisleilizumab (PD-1 Antibody) and Chemoradiotherapy in Locoregionally-advanced Nasopharyngeal CarcinomaNot yet recruitingNCT04870905Phase 21 country
- Modulation Therapy for Locally Advanced NPC Based on Plasma EBV DNA Level Post-ICTRecruitingNCT05628922Phase 21 country
- Fluzoparib and Camrelizumab in Treating Patients With R/M NPC That Progressed After First-line ChemotherapyRecruitingNCT04978012Phase 21 country
- Endoscopic Nasopharyngectomy for Newly Diagnosed Stage I Nasopharyngeal Carcinoma PatientsRecruitingNCT03353467Not applicable1 country
- Concurrent and Adjuvant PD1 Treatment Combined With Chemo-radiotherapy for High-risk Nasopharyngeal CarcinomaRecruitingNCT04453826Phase 31 country
- Oligo-metastases NPC Patients Received Radiation for Primary Tumors and Treatments for Metastatic LesionsRecruitingNCT03129412Phase 21 country
- Sensor-Assisted Prevention of Dehydration in Head and Neck Cancer PatientsActive, not recruitingNCT02253238Not applicable1 country
- Nivolumab in Treating Patients With Recurrent and/or Metastatic Nasopharyngeal CancerCompletedNCT02339558Phase 23 countries
- P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid TumorsActive, not recruitingNCT05239143Phase 11 country
- Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and NeckCompletedNCT02113878Phase 11 country
- The Clinical Application Value of CAIX-Targeted PET Hypoxia Imaging in Malignant TumorsActive, not recruitingNCT078900381 country
- A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced CancersActive, not recruitingNCT05544929Phase 112 countries
- Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell CarcinomaCompletedNCT03082534Phase 21 country
- Atezolizumab and Bevacizumab in Treating Patients With Rare Solid TumorsActive, not recruitingNCT03074513Phase 21 country