Mitral Valve Insufficiency: all 467 studies

Page 4 of 5. Open to participants first (152), then studies with results posted, then the rest; newest registration first within each.

• Early Feasibility EXperience of Posterior Leaflet RestOration to REduce Mitral RegurgitationTerminatedNCT04098328
• Safety and Performance Study of the MitralStitch Repair System.Status unknownNCT04080362Not applicable
• Primary Mitral Regurgitation RepairStatus unknownNCT04067635
• MitralStitch Mitral Valve Repair System for Mitral RegurgitationStatus unknownNCT04061837Not applicable
• The Effects of Degenerative Mitral Regurgitation on Cardiac Structure and Function, Symptoms, and Exercise CapacityStatus unknownNCT04051411
• Comparison Study of Echocardiography and Cardiovascular Magnetic Resonance Imaging in the Assessment of Mitral and Aortic RegurgitationStatus unknownNCT04038879
• Transcatheter Treatment for Combined Aortic and Mitral Valve Disease. The Aortic+Mitral TRAnsCatheter (AMTRAC) Valve RegistryStatus unknownNCT04031274
• Stress Echo for Ischemic Mitral Valve SurgerySuspendedNCT04023058Not applicable
• Treatment of Concomitant Mitral Regurgitation by Mitral Valve Clipping in Patients With Successful Transcatheter Aortic Valve Implantation.Status unknownNCT04009434Not applicable
• Cephea Transseptal Mitral Valve System FIHCompletedNCT03988946Not applicable
• Exercise-induced in Secondary Mitral Regurgitation: Analysis of Echocardiographic Parameters at Rest Predicting the Onset of Significant Exercise-induced Mitral RegurgitationCompletedNCT03978676
• Use of Pre-operative Global Longitudinal Strain to Predict Post-operative Left Ventricular Dysfunction in Mitral Regurgitation SurgeryCompletedNCT03968601
• Structural Heart and Valve Network PROSPECTIVE RegistryWithdrawnNCT03928639
• The Conveyor StudyStatus unknownNCT03893578Not applicable
• Transcatheter Mitral Valve Repair for the Treatment of Mitral Valve Regurgitation In Heart Failure (The EVOLVE-MR Trial)TerminatedNCT03891823Not applicable
• Left Chamber Function in Mitral Regurgitation and Predicting Outcome After Replacement and Targeting for Early SurgeryStatus unknownNCT03870516Not applicable
• Epicardial Mitral Repair Trial - ENRAPT-MRStatus unknownNCT03864848Not applicable
• OPtimisation of Surgical Repair for Treating Insufficiency of the MItral Valve - Safety EvaluationCompletedNCT03842397Not applicable
• Feasibility Study of Patients With Severe MR Treated With the Cardiovalve TMVR SystemWithdrawnNCT03714412Not applicable
• Edwards PASCAL CLASP IID/IIF Pivotal Clinical TrialActive, not recruitingNCT03706833Not applicable
• MitraClip for the Treatment of Moderate Functional Mitral Regurgitation: EVOLVE-MRStatus unknownNCT03705312Not applicable
• Caisson Transcatheter Mitral Valve Replacement (TMVR)Active, not recruitingNCT03661398Not applicable
• VenTouch OUS Feasibility StudyStatus unknownNCT03616678Not applicable
• Patient Specific Mitral Valve Modeling for Surgical Planning and TrainingStatus unknownNCT03609931
• Edwards Cardioband European Post-Market Study, MiBANDStatus unknownNCT03600688
• Automated Phonocardiography Analysis in AdultsCompletedNCT03600051
• A Pan-Canadian, Retrospective Evaluation of MitraClip Safety and EfficacyCompletedNCT03592043
• ChordArt System for Mitral RegurgitationStatus unknownNCT03581656Not applicable
• Surgical Valvuloplasty for Congenital Mitral InsufficiencyStatus unknownNCT03567668
• Early Feasibility Study of the AccuCinch® Ventricular Restoration System in Patients With Prior Mitral Valve Intervention (PMVI) and Recurrent Mitral RegurgitationCompletedNCT03560167Not applicable
• Mitral Valve Repair Combined Coronary Artery Bypass Grafting(CABG) Verus CABG Alone on Functional Ischemic Mitral RegurgitationStatus unknownNCT03525041Not applicable
• GIse Registry Of Transcatheter Treatment of Mitral Valve regurgitaTiOn (GIOTTO)Active, not recruitingNCT03521921
• Observational Study of the Heart Repair Technologies Mitral Bridge in Treating Mitral Valve RegurgitationTerminatedNCT03511716
• Noninferiority Trial of MitraClip Implantation Strategies: 1 Clip vs. 2 Clips in Patients With Functional Mitral RegurgitationWithdrawnNCT03503851Not applicable
• Operative Mitral Valve Reconstruction in Functional mv Insufficiency With Reduced Systolic Ventricle FunctionCompletedNCT03470155
• Phono- and Electrocardiogram Assisted Detection of Valvular DiseaseCompletedNCT03458806
• Atrial Functional Mitral Regurgitation Response In Mitral Loop Cerclage Annuloplasty (AFRICA Study)CompletedNCT03453853Phase 1/2
• AHEAD: European Feasibility Study of the Cardiovalve Transfemoral Mitral Valve SystemActive, not recruitingNCT03339115Not applicable
• Unmasking the dynAmic Component in functionaL mitraL rEGuRgitatiOn in Chronic Heart FailureStatus unknownNCT03315429Not applicable
• MitrAl ValvE RepaIr Clinical Trial (MAVERIC Trial) - United StatesTerminatedNCT03311295Not applicable
• Prospective Treatment Algorithm Guiding Repair of Severe Ischemic Mitral RegurgitationActive, not recruitingNCT03292497Not applicable
• Mitral Valve Regurgitation Quantification From 3D Color Doppler Ultrasound - Standard of Care Data CollectionCompletedNCT03286088Not applicable
• Flexible Band vs Rigid Ring for Degenerative Mitral Valve DiseaseCompletedNCT03278574Not applicable
• Multicentre Study of MITRACLIP® Transcatheter Mitral Valve Repair in Patients With Severe Primary Mitral Regurgitation Eligible for High-risk SurgeryActive, not recruitingNCT03271762Not applicable
• SAPIEN M3 EFS: Early Feasibility Study of the Edwards SAPIEN M3 System for the Treatment of Mitral RegurgitationCompletedNCT03230747Not applicable
• The BOSS Study: An Acute Evaluation of Anatomical and Geometric Changes Using the Bladder on a Stick System (BOSS)CompletedNCT03228381Not applicable
• Cardiopulmonary Exercise Testing in Severe Mitral RegurgitationCompletedNCT03154034
• Clinical and Geriatric Assessment in Elderly Patients Before and After TAVI or MitraClip PositioningStatus unknownNCT03145376
• MitraClip in Acute Mitral RegurgitationCompletedNCT03107455
• Coronary and Structural Interventions Ulm - Transcatheter Mitral Valve Repair (CSI-Ulm-TMVR)CompletedNCT03104660Not applicable
• Silent sTROke duriNG MitraClip ImplantationCompletedNCT03104556
• Long Term Follow Up for CTSN Mitral Valve Repair StudiesActive, not recruitingNCT03066050
• Tiara™ Transcatheter Mitral Valve Replacement StudyCompletedNCT03039855Not applicable
• The Papillary Muscle Approximation Provide Stability of Mitral Valve Repair for Ischemic Mitral RegurgitationStatus unknownNCT03038204
• MitraClip® and Hemodynamic Effects of Relevant Iatrogenic Atrial Septum Defect ClosureStatus unknownNCT03024268Not applicable
• MRI as a Predictor of Outcomes in Patients Undergoing Mitral Valve SurgeryStatus unknownNCT03012178
• Evaluation of Outcomes of CRT and MitraClip for Treatment of Low Ejection Fraction and Functional Mitral Regurgitation in HFWithdrawnNCT02985268Not applicable
• HighLife™ Transcatheter Mitral Valve Replacement System StudyCompletedNCT02974881Not applicable
• Hemodynamic Stress Test in Severe Mitral Regurgitation (HEMI)Status unknownNCT02961647
• MERIT Study - Mistral Percutaneous Mitral Valve Repair FIM StudyCompletedNCT02948231Not applicable
• Effect of MitraClip on Acute and Chronic Reverse Cardiac Remodeling Assessed by CMR: The MITRA-REVERSE StudyCompletedNCT02924363
• A Feasibility Registry of Actigraphy Monitoring in Degenerative Mitral Regurgitation Subjects Receiving the MitraClip® DeviceTerminatedNCT02858245
• MitraClip® After Surgical Mitral Valve RepairStatus unknownNCT02853955
• Acute Normovolemic Hemodilution on Serum-creatinine Concentration in Cardiac SurgeryCompletedNCT02831270
• Effectiveness and Safety of Mitral Valve Repair With the NeoChord DS1000 Artificial Chordae Delivery System Versus Conventional Surgery in Patients With Severe Primary Mitral Regurgitation Due to Isolated Leaflet ProlapseWithdrawnNCT02829749Not applicable
• Magnetic Resonance Imaging for Cerebral Embolization During Minimal Invasive Mitral Valve SurgeryStatus unknownNCT02818166Not applicable
• The CorCinch - Functional Mitral Valve Regurgitation (FMR) StudyCompletedNCT02806570Not applicable
• Randomized Trial of the Neochord DS1000 System Versus Open Surgical RepairActive, not recruitingNCT02803957Not applicable
• Caisson Transcatheter Mitral Valve Replacement (TMVR) System Early Feasibility StudyStatus unknownNCT02768402Not applicable
• Incidence of Significant Mitral Regurgitation in Acute Heart Failure PatientsCompletedNCT02728739Not applicable
• CardiAQ-Edwards™ Transcatheter Mitral Valve Replacement (TMVR) StudyWithdrawnNCT02722551Phase 1/2
• Mitral Valve Replacement With MValve Dock and LotusStatus unknownNCT02719912Not applicable
• Edwards EVOQUE Eos MISCEND StudyActive, not recruitingNCT02718001Not applicable
• Evaluation of Safety and Efficacy of the BACE™ Device in the Treatment of Functional Mitral Valve Regurgitation [FMRStatus unknownNCT02701972Not applicable
• Remote Monitoring of Patients With Functional Mitral Regurgitation Undergoing Mitraclip Transcatheter RepairStatus unknownNCT02698150
• Pharmacological Reduction of Functional, Ischemic Mitral REgurgitationCompletedNCT02687932Phase 4
• Evaluation of the Minimally Invasive VenTouch™ System in the Treatment of Functional Mitral Valve Regurgitation (FMR)Status unknownNCT02671799Not applicable
• Expiratory Flow Limitation and Mechanical Ventilation During Cardiopulmonary Bypass in Cardiac SurgeryStatus unknownNCT02633423Not applicable
• Safety and Performance of the AccuCinch® SystemWithdrawnNCT02624960Not applicable
• Annular Reshaping of the Mitral Valve for Patients With Mitral Regurgitation Using the Millipede IRIS SystemCompletedNCT02607527Not applicable
• Degenerative Mitral Regurgitation in Intermediate Risk PatientsCompletedNCT02604745
• AMENDTM Mitral Valve Repair System, Annuloplasty Ring Applied in a Transcatheter MethodCompletedNCT02602613Not applicable
• (MitraClip in Non-Responders to Cardiac Resynchronization Therapy)Status unknownNCT02592889Phase 4
• High and Intermediate Risk Degenerative Mitral Regurgitation Treatment: A Trial Comparing MitraClip® to Surgical TherapyTerminatedNCT02534155Phase 4
• Early Feasibility Study of the CardiAQ™ TMVI System (Transfemoral and Transapical DS)WithdrawnNCT02515539Not applicable
• Belgian Mitraclip RegistryCompletedNCT02506387
• Acute Normovolemic Hemodilution on ROTEM in Cardiac SurgeryCompletedNCT02502448Not applicable
• A Clinical Study of the CardiAQ™ TMVI System (Transapical DS)TerminatedNCT02478008Not applicable
• Mitral Loop Cerclage(MLC) for Reducing Functional Mitral RegurgitationCompletedNCT02471664Not applicable
• A Clinical Evaluation of the Safety and Effectiveness of the MitraClip System in the Treatment of Clinically Significant Functional Mitral RegurgitationCompletedNCT02444338Not applicable
• The RESHAPE-HF1-FU StudyWithdrawnNCT02444286
• Twelve Transcatheter Mitral Valve Replacement (TMVR) Pilot StudyTerminatedNCT02428010Not applicable
• Physical and Functional Recovery From Cardiac Surgery in Hospitalized Patients: A Feasibility Pilot StudyCompletedNCT02375282Not applicable
• Normal Values in Stress Echocardiographic Parameters in Patients After Successful Mitral Valve Repair for Organic MRCompletedNCT02371863
• A Multicenter, Randomized, Controlled Study to Assess Mitral vAlve reconsTrucTion for advancEd Insufficiency of Functional or iscHemic ORigiNStatus unknownNCT02371512Not applicable
• The Role of Myocardial Fibrosis in Degenerative Mitral RegurgitationCompletedNCT02355418
• Treatment of Heart Failure and Associated Functional Mitral Valve RegurgitationStatus unknownNCT02302872Not applicable
• Feasibility of the AccuCinch® System for Left Ventricular Reshaping of the Mitral Apparatus to Reduce Functional Mitral Regurgitation and Improve Left Ventricular FunctionCompletedNCT02153892Not applicable
• The CardioPAT Project: A Randomized TrialTerminatedNCT02058134Not applicable
• Surgical Treatment of Hypertrophic Obstructive Cardiomyopathy With Severe Mitral Insufficiency.CompletedNCT02054221Not applicable

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