Leptospirosis clinical trials

The registry lists 25 studies for Leptospirosis across more than 10 countries. 11 are recruiting or about to start. 20 of them are mainly about Leptospirosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-03.

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Status

Completed: 8
Not yet recruiting: 6
Recruiting: 4
Status unknown: 4
Active, not recruiting: 1
Enrolling by invitation: 1

Phase

Phase 2: 3
Phase 4: 2
Phase 3: 1

Where

France: 6
Réunion: 3
Cambodia: 2
French Guiana: 2
Martinique: 2
Thailand: 2

Who runs them

Institut Pasteur (3) · University Hospital Center of Martinique (3) · Centre Hospitalier Universitaire de la Réunion (3) · Chulalongkorn University (2) · National Kidney and Transplant Institute, Philippines (1) · Imaxio (1) · Dr Cipto Mangunkusumo General Hospital (1) · Centre Hospitalier de Cayenne (1)

What is being tested here

Drugs under test in Leptospirosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	Phase 3	All
Doxycycline	1	0	1
Acetylcysteine	0	0	1
Dexamethasone	0	1	1
Deamino Arginine Vasopressin	0	1	1

Coming up

0phase 3 studies under way

3studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 3

Dec 2026These Studies That Evaluated the Efficacy of Antibiotics for Leptospirosis Treatment. · Chulalongkorn University
Mar 2027Preventive Strategies for Early and Late Complications of Leptospirosis · National Kidney and Transplant Institute, Philippines
Oct 2027Comparing Two Antibiotic Therapy Periods (3 Versus 7 Days) in Patients With Mild Leptospirosis and Seen at the Hospital in 5 French Overseas Departments (Martinique, Guadeloupe, French Guiana, Reunion, Mayotte) · University Hospital Center of Martinique

Who these studies take

Of the 4 Leptospirosis studies recruiting now, 2 (50%) set no upper age limit and 2 (50%) stop at 75 or younger. 2 (50%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (25%) take healthy volunteers.

Recruiting studies that take each age, of 4
Age	Women	Men
10	2 (50%)	2 (50%)
18	4 (100%)	4 (100%)
30	4 (100%)	4 (100%)
40	4 (100%)	4 (100%)
50	4 (100%)	4 (100%)
65	3 (75%)	3 (75%)
75	3 (75%)	3 (75%)
85	2 (50%)	2 (50%)

Across all 25 studies, recruiting or not: 12% stop at 75 or younger and 8% at 65; 36% take children; 0% are for women only and 0% for men only; 32% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

Studies

Recruiting first, then most recently updated. Showing 25 of 25. search them.