Congenital Hypothyroidism clinical trials
The registry lists 27 studies for Congenital Hypothyroidism across more than 10 countries. 9 are recruiting or about to start. 21 of them are mainly about Congenital Hypothyroidism (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Status
Phase
- Phase 4
- 3
Who runs them
IRCCS Azienda Ospedaliero-Universitaria di Bologna (2) · Zhejiang University (2) · Federico II University (2) · University of Sao Paulo (1) · Ain Shams University (1) · University Children's Hospital Basel (1) · Buzzi Children's Hospital (1) · McGill University (1)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Nov 2026Early Check: Expanded Screening in Newborns · RTI International
- Dec 2026Infants With Primary Congenital Hypothyroidism and Development · Nigde Omer Halisdemir University
- May 2027Ultrasound Measurement of Thyroid Volume in Term Newborns · IRCCS Ospedale San Raffaele
- Nov 2027Role of Next Generation Sequencing in the Etiological Diagnosis of Permanent Congenital Hypothyroidism With in Situ Thyroid · IRCCS Azienda Ospedaliero-Universitaria di Bologna
Who these studies take
Of the 6 Congenital Hypothyroidism studies recruiting now, 1 (17%) set no upper age limit and 5 (83%) stop at 75 or younger. 6 (100%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (33%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (67%) | 4 (67%) |
| 18 | 3 (50%) | 3 (50%) |
| 30 | 1 (17%) | 1 (17%) |
| 40 | 1 (17%) | 1 (17%) |
| 50 | 1 (17%) | 1 (17%) |
| 65 | 1 (17%) | 1 (17%) |
| 75 | 1 (17%) | 1 (17%) |
| 85 | 1 (17%) | 1 (17%) |
Across all 27 studies, recruiting or not: 81% stop at 75 or younger and 81% at 65; 89% take children; 7% are for women only and 0% for men only; 44% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
- Ultrasound Measurement of Thyroid Volume in Term NewbornsNov 10, 2026NCT07579988
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 27 of 27. search them.
- Ultrasound Measurement of Thyroid Volume in Term NewbornsRecruitingNCT075799881 country
- Understanding the Subnormal Rescue ofNeurological Development in Congenital Hypothyroidism (2022E5SZEM)RecruitingNCT078935221 country
- Prospective Evaluation of OptiThyDoseRecruitingNCT06864351Not applicable3 countries
- Evaluation of an Intensified Systematic Screening for Congenital Hypothyroidism in Premature NewbornsNot yet recruitingNCT074250281 country
- Role of Next Generation Sequencing in the Etiological Diagnosis of Permanent Congenital Hypothyroidism With in Situ ThyroidRecruitingNCT067287351 country
- Comparison of Levothyroxine Formulations in the Treatment of Congenital HypothyroidismRecruitingNCT067242241 country
- Infants With Primary Congenital Hypothyroidism and DevelopmentRecruitingNCT072801041 country
- Metabolic Risk Assessment in Prepubertal Children With Congenital HypothyroidismNot yet recruitingNCT071263531 country
- Quality of Life and Long-term Outcome of Adequately Treated Congenital HypothyroidismEnrolling by invitationNCT06864039Not applicable1 country
- Levothyroxine Dosing in Neonatal Congenital HypothyroidismCompletedNCT07754370Phase 41 country
- Early Check: Expanded Screening in NewbornsActive, not recruitingNCT036552231 country
- Use of Tirosint®-SOL or Tablet Formulations of Levothyroxine in Pediatric Patients With Congenital Hypothyroidism (CH)TerminatedNCT05228184Phase 41 country
- Clinical and Genetic Analysis in Congenital Hypothyroidism Due to Thyroid Dysgenesis.CompletedNCT01916018Not applicable1 country
- Baby Detect : Genomic Newborn ScreeningCompletedNCT056874741 country
- Iodine Impact on Thyroid Function and Psychomotor Development, Observational Study in the Portuguese Minho RegionActive, not recruitingNCT042885311 country
- Influence of Initial Levothyroxine Dose on Neurodevelopmental and Growth Outcomes in Congenital HypothyroidismCompletedNCT05371262Phase 4
- Final Height in Patients With CH Diagnosed by the ScreeningStatus unknownNCT047344571 country
- Congenital Hypothyroidism in Children With Eutopic Gland or Thyroid Hemiagenesis: Predictive Factors for Transient vs Permanent Hypothyroidism.Status unknownNCT047127601 country
- Generic vs. Name-Brand LevothyroxineCompletedNCT00403390Not applicable1 country
- A Study of 99m Tc Pertechnetate Produced in High Energy Cyclotron in Patients With Thyroid Scan IndicationCompletedNCT023071751 country
- Targeted Levothyroxine Dosing in Infants With Congenital HypothyroidismCompletedNCT02374593Not applicable1 country
- The Effects of Iodized Salt on Cognitive Development in EthiopiaCompletedNCT01349634Not applicable1 country
- The Prevalence of Hearing Loss Among Children With Congenital HypothyroidismWithdrawnNCT012236381 country
- Clinical Evaluation of NeoPlex4 Assay and NeoPlex SystemCompletedNCT014887211 country
- Iodine Status in Pregnant Women and Their Newborns: is Congenital Hypothyroidism Related to Iodine Deficiency in Pregnancy?Status unknownNCT005054791 country
- Diagnosis and Follow-up of Patients With Subclinical HypothyroidismCompletedNCT00497575
- TG Gene Mutations and Congenital HypothyroidismCompletedNCT00493103