Congenital Hypothyroidism clinical trials
The registry lists 27 studies for Congenital Hypothyroidism across more than 10 countries. 9 are recruiting or about to start. 21 of them are mainly about Congenital Hypothyroidism (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Phase
- Phase 4
- 3
Who runs them
IRCCS Azienda Ospedaliero-Universitaria di Bologna (2) · Federico II University (2) · Zhejiang University (2) · Buzzi Children's Hospital (1) · Boston Children's Hospital (1) · Erica Eugster (1) · McGill University (1) · Centre de recherche du Centre hospitalier universitaire de Sherbrooke (1)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Nov 2026Early Check: Expanded Screening in Newborns · RTI International
- Dec 2026Infants With Primary Congenital Hypothyroidism and Development · Nigde Omer Halisdemir University
- May 2027Ultrasound Measurement of Thyroid Volume in Term Newborns · IRCCS Ospedale San Raffaele
- Nov 2027Role of Next Generation Sequencing in the Etiological Diagnosis of Permanent Congenital Hypothyroidism With in Situ Thyroid · IRCCS Azienda Ospedaliero-Universitaria di Bologna
Who these studies take
Of the 6 Congenital Hypothyroidism studies recruiting now, 1 (17%) set no upper age limit and 5 (83%) stop at 75 or younger. 6 (100%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (33%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (67%) | 4 (67%) |
| 18 | 3 (50%) | 3 (50%) |
| 30 | 1 (17%) | 1 (17%) |
| 40 | 1 (17%) | 1 (17%) |
| 50 | 1 (17%) | 1 (17%) |
| 65 | 1 (17%) | 1 (17%) |
| 75 | 1 (17%) | 1 (17%) |
| 85 | 1 (17%) | 1 (17%) |
Across all 27 studies, recruiting or not: 81% stop at 75 or younger and 81% at 65; 89% take children; 7% are for women only and 0% for men only; 44% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
- Ultrasound Measurement of Thyroid Volume in Term NewbornsNov 10, 2026NCT07579988
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 27 of 27. search them.
- Ultrasound Measurement of Thyroid Volume in Term NewbornsRecruitingNCT075799881 country
- Understanding the Subnormal Rescue ofNeurological Development in Congenital Hypothyroidism (2022E5SZEM)RecruitingNCT078935221 country
- Prospective Evaluation of OptiThyDoseRecruitingNCT06864351Not applicable3 countries
- Evaluation of an Intensified Systematic Screening for Congenital Hypothyroidism in Premature NewbornsNot yet recruitingNCT074250281 country
- Role of Next Generation Sequencing in the Etiological Diagnosis of Permanent Congenital Hypothyroidism With in Situ ThyroidRecruitingNCT067287351 country
- Comparison of Levothyroxine Formulations in the Treatment of Congenital HypothyroidismRecruitingNCT067242241 country
- Infants With Primary Congenital Hypothyroidism and DevelopmentRecruitingNCT072801041 country
- Metabolic Risk Assessment in Prepubertal Children With Congenital HypothyroidismNot yet recruitingNCT071263531 country
- Quality of Life and Long-term Outcome of Adequately Treated Congenital HypothyroidismEnrolling by invitationNCT06864039Not applicable1 country
- Levothyroxine Dosing in Neonatal Congenital HypothyroidismCompletedNCT07754370Phase 41 country
- Early Check: Expanded Screening in NewbornsActive, not recruitingNCT036552231 country
- Use of Tirosint®-SOL or Tablet Formulations of Levothyroxine in Pediatric Patients With Congenital Hypothyroidism (CH)TerminatedNCT05228184Phase 41 country
- Clinical and Genetic Analysis in Congenital Hypothyroidism Due to Thyroid Dysgenesis.CompletedNCT01916018Not applicable1 country
- Baby Detect : Genomic Newborn ScreeningCompletedNCT056874741 country
- Iodine Impact on Thyroid Function and Psychomotor Development, Observational Study in the Portuguese Minho RegionActive, not recruitingNCT042885311 country
- Influence of Initial Levothyroxine Dose on Neurodevelopmental and Growth Outcomes in Congenital HypothyroidismCompletedNCT05371262Phase 4
- Final Height in Patients With CH Diagnosed by the ScreeningStatus unknownNCT047344571 country
- Congenital Hypothyroidism in Children With Eutopic Gland or Thyroid Hemiagenesis: Predictive Factors for Transient vs Permanent Hypothyroidism.Status unknownNCT047127601 country
- Generic vs. Name-Brand LevothyroxineCompletedNCT00403390Not applicable1 country
- A Study of 99m Tc Pertechnetate Produced in High Energy Cyclotron in Patients With Thyroid Scan IndicationCompletedNCT023071751 country
- Targeted Levothyroxine Dosing in Infants With Congenital HypothyroidismCompletedNCT02374593Not applicable1 country
- The Effects of Iodized Salt on Cognitive Development in EthiopiaCompletedNCT01349634Not applicable1 country
- The Prevalence of Hearing Loss Among Children With Congenital HypothyroidismWithdrawnNCT012236381 country
- Clinical Evaluation of NeoPlex4 Assay and NeoPlex SystemCompletedNCT014887211 country
- Iodine Status in Pregnant Women and Their Newborns: is Congenital Hypothyroidism Related to Iodine Deficiency in Pregnancy?Status unknownNCT005054791 country
- Diagnosis and Follow-up of Patients With Subclinical HypothyroidismCompletedNCT00497575
- TG Gene Mutations and Congenital HypothyroidismCompletedNCT00493103