Carcinoma, Squamous Cell: all 1,779 studies

Page 9 of 18. Open to participants first (409), then studies with results posted, then the rest; newest registration first within each.

• Surgical Margin Assessment by 3D UltrasoundStatus unknownNCT05740774Not applicable
• Cemiplimab/Peg-Interferon-α in Advanced CSCCWithdrawnNCT05729139Phase 1
• Neoadjuvant Tislelizumab in Combination With Dasatinib and Quercetin in Resectable HNSCC (COIS-01)Active, not recruitingNCT05724329Phase 2
• The Long Non Coding MALAT1 as a Potential Salivary Diagnostic Biomarker in Oral Squamous Cell Carcinoma Through Targeting mi RNA 124CompletedNCT05708209
• Phase 2 Trial of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab in Patients With Newly Diagnosed PD-L1 CPS Positive Resectable Stage 3-4 Oral Cavity Squamous Cell Carcinoma (OCSCC).Active, not recruitingNCT05681039Phase 2
• Pyrimethamine as an Inhibitor of NRF2 in HPV-unrelated Locally Advanced Head and Neck Squamous Cell CarcinomaCompletedNCT05678348Early Phase 1
• A Phase 1b Study of WU-NK-101 in Combination With CetuximabActive, not recruitingNCT05674526Phase 1
• Camrelizumab Combined With Neoadjuvant Concurrent Chemoradiotherapy for Resectable Locally Advanced ESCC（NICE-RT）Status unknownNCT05650216Phase 2
• Post-Operative Radiotherapy De-Escalation of Negative Nodal Regions in Head and Neck Squamous Cell CarcinomaStatus unknownNCT05650034Not applicable
• Sentinel NOSE Study: Prospective Registration Study on the Sentinel Node Procedure for Bulky Squamous Cell Carcinoma of the Nasal Vestibule.CompletedNCT05637307Not applicable
• A Phase II Clinical Study of Fruquintinib Combined With S-1 for Advanced Esophageal Squamous Cell CarcinomaStatus unknownNCT05636150Phase 2
• Peripheral Blood Neoantigen Specific T Cells Predict the Efficacy of Immunotherapy for Esophageal Squamous Cell CarcinomaStatus unknownNCT05633641
• Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic CancerActive, not recruitingNCT05620134Phase 1/2
• The Impact of Two-field or Three-field Lymphadenectomy on Overall Survival in Middle and Lower Thoracic Esophageal Squamous Cell Carcinoma: An Observational StudyCompletedNCT05617352
• Camrelizumab Plus Docetaxel and Cisplatin in Recurrent or Metastatic Oral Squamous Cell Carcinoma PatientsStatus unknownNCT05611463Phase 2
• T1 Squamous Cell Carcinomas of the LipActive, not recruitingNCT05610293
• A Clinical Study to Investigate the Efficacy of Tigilanol Tiglate Directly in Head and Neck CancerActive, not recruitingNCT05608876Phase 2
• Vorinostat in Combination With Chemoradiation in Locally Advanced HPV Negative HNSCCWithdrawnNCT05608369Phase 2
• A Study of [225Ac]-FPI-2059 in Adult Participants With Solid TumoursTerminatedNCT05605522Phase 1
• Surgery Versus Non-surgical Treatment for Esophageal Squamous Cell Carcinoma in Patients Older Than 70 YearsCompletedNCT05604950
• Tislelizumab With Chemotherapy or Radiation for Neoadjuvant Therapy of Esophageal Squamous Cell Carcinoma (TINES)Status unknownNCT05603065Phase 4
• Efficacy and Safety of Neoadjuvant Pembrolizumab in III-IVA Resectable Oral Squamous Cell CarcinomaStatus unknownNCT05578170
• A Study of Radiation Therapy and Cemiplimab for People With Skin CancerActive, not recruitingNCT05574101Phase 2
• RESECTED LYMPH NODES AND SURVIVAL OF PATIENTS WITH ESOPHAGEAL SQUAMOUS CELL CARCINOMA: AN OBSERVATIONAL STUDYStatus unknownNCT05570487
• Vitamin-D Receptor in Laryngeal Squamous Cell CarcinomaStatus unknownNCT05568641
• Sequential Preoperative Penpulimab Combined With Chemoradiotherapy(CRT) for Locally Advanced Esophageal Squamous Cell CancerStatus unknownNCT05561699Not applicable
• Identification of Breath Biomarkers in Esophageal CancerCompletedNCT05557955
• Artesunate Suppositories for the Treatment of HIV-negative Patients With Intra-anal HSILActive, not recruitingNCT05555862Phase 2
• SCT200 in Combination With SCT-I10A/Paclitaxel/Docetaxel in Recurrent/Metastatic Head and Neck Squamous Cell CarcinomaStatus unknownNCT05552807Phase 1
• Envafolimab Combined With Chemotherapy in Neoadjuvant Therapy for Resectable Esophageal Squamous Cell CarcinomaStatus unknownNCT05552651Phase 2
• Efficacy and Safety of Tislelizumab and Nab-paclitaxel Combined With Low-dose Radiotherapy in Patients With Stage IVb Esophageal Squamous Cell CarcinomaStatus unknownNCT05547828Phase 2
• Pembrolizumab Plus CRT Followed by Surgery in Upper ESCCStatus unknownNCT05541445Phase 1/2
• A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid TumorsCompletedNCT05538572Phase 1
• Phase 2 Study of Neoadjuvant SAR444245 Plus Cemiplimab in HPV Related Oropharynx Squamous Cell CarcinomaWithdrawnNCT05535023Phase 2
• Induction Modified TPF Followed by Concurrent Chemoradiotherapy in Locally Advanced Squamous Cell Carcinoma of the Head and NeckActive, not recruitingNCT05527782Phase 2
• AK104 Alone or in Combination With Chemotherapy in the First-line Treatment of ESCCStatus unknownNCT05522894Phase 2
• Combination of Tislelizumab and Chemoradiotherapy in Esophageal Cancer (EC-CRT-002)Active, not recruitingNCT05520619Phase 2
• Neoadjuvant Chemotherapy, Tislelizumab With Afatinib for HNSCCCompletedNCT05516589Phase 2
• Real World Study on the Use of Cemiplimab in Adult Patients in UKCompletedNCT05493826
• Decisional Conflicts, Health-related QoL and Satisfaction With Care in High-risk cSCC in the Head-neck RegionCompletedNCT05482880
• Selected De-escalation Radiotherapy for Postoperative Head and Neck Squamous Cell CarcinomaStatus unknownNCT05476965Phase 2
• Neoadjuvant Therapy of Camrelizumab Combined With Chemotherapy for Resectable Locally Advanced Esophageal Squamous Cell CarcinomaStatus unknownNCT05476380Phase 2
• Alpelisib in Combination With Carboplatin in Patients With Solid Tumors and HPV-Positive Squamous Cell CarcinomaWithdrawnNCT05472220Phase 1
• Adjuvant Radiotherapy for Patients With Esophageal Squamous Cell Carcinoma After R0 ResectionStatus unknownNCT05460403
• Reducing Excision Margins After Neoadjuvant Chemoimmunotherapy for HPV Negative Resectable Locally Advanced HNSCCActive, not recruitingNCT05459415Not applicable
• Therapeutic Efficacy of Quercetin Versus Its Encapsulated Nanoparticle on Tongue Squamous Cell Carcinoma Cell LineStatus unknownNCT05456022Phase 2
• Postoperative Radiotherapy for Oral Squamous Cell Carcinoma After Neoadjuvant Therapy and SurgeryCompletedNCT05455632
• ctDNA-based MRD Assessment in Local Advanced Esophageal CarcinomaStatus unknownNCT05426850
• Short Course Neoadjuvant Chemo-radiotherapy Plus Toripalimab for Locally Advanced Resectble Squamous Cell Carcinoma of EsophagusStatus unknownNCT05424432Phase 2
• Pilot Trial of E Cigarettes in Pts Diagnosed With Cancer of the Head, Neck, and LungWithdrawnNCT05412875Not applicable
• Assessment of Squamous Cell Carcinoma antigen2 in Verruca VulgarisStatus unknownNCT05409365
• ITIL-168 in Advanced Solid TumorsWithdrawnNCT05393635Phase 1
• Pembrolizumab and Photodynamic Therapy in Previously Treated Metastatic Esophageal Squamous Cell CarcinomaStatus unknownNCT05386056Phase 2
• Esophageal Arterial Infusion Chemotherapy Versus Systemic Intravenous Chemotherapy for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma: a Prospective, Multicentre, Randomised Controlled Clinical StudyStatus unknownNCT05381636Phase 2
• Pembrolizumab Plus Olaparib in LA-HNSCCActive, not recruitingNCT05366166Phase 2
• INCAGN01876 in Combination With Immunotherapy in Participants With Recurrent or Metastatic Head and Neck Squamous Cell CarcinomaWithdrawnNCT05359692Phase 2
• Nimotuzumab Combined With Neoadjuvant Chemotherapy in the Treatment of Resectable LA HNSCCStatus unknownNCT05351762Phase 2
• Tislelizumab Combined With Neoadjuvant Radiotherapy and Chemotherapy for Resectable Esophageal Squamous Cell Carcinoma.Status unknownNCT05323890Phase 2
• Alpha Radiation Emitters Device (DaRT) for the Treatment of Recurrent Cutaneous Squamous Cell CarcinomaActive, not recruitingNCT05323253Not applicable
• A Pilot Study of Glutamine PET Imaging of Head and Neck Squamous Cell CarcinomaTerminatedNCT05322135Early Phase 1
• Prospective Evaluation of ENDOSWIR Device Versus Pathology for Squamous Cell Carcinoma of Upper Aerodigestive Tract (ENDOSWIR-VADS)Status unknownNCT05318872
• A Translational Study of Tumor Antigen-pulsed DC Vaccine for ESCCStatus unknownNCT05317325Phase 1
• Comparative Efficacy of Cemiplimab to Historical Standard of Care in FranceCompletedNCT05302297
• Neoadjuvant Pembrolizumab Plus Chemotherapy for Resectable Locally Advanced Esophageal Squamous Cell CarcinomaCompletedNCT05302011Phase 2
• Usefulness of Integrated PET/MRI in Oropharyngeal Squamous Cell Carcinoma EvaluationCompletedNCT05299957
• BH4 in the Prevention and Treatment of Radiation-induced Skin Reactions for Head and Neck Squamous Cell Carcinoma (Including Nasopharyngeal Carcinoma)Status unknownNCT05299203Phase 1
• IMP3 and PCNA Expression in Laryngeal Squamous Cell Carcinoma in Sohag GovernorateStatus unknownNCT05293327
• Effect of Accelerated RTH in Squamous Cell Carcinoma in Head and NeckStatus unknownNCT05291663
• Quantitative Analysis of 18F-FAPI Dynamic PET/CT for Accurate Differential Diagnosis of MLN of ESCCStatus unknownNCT05287880
• Decitabine Plus Penpulimab as Second-line Therapy for Advanced ESCC Treated With PD-1 BlockadeStatus unknownNCT05265962Phase 2
• The Efficacy and Safety of HLX07 in Locally Advanced or Metastatic Cutaneous Squamous Cell Carcinoma (CSCC)Status unknownNCT05238363Phase 2
• A Safety and Preliminary Efficacy Study of SBT6290 Alone and in Combination With PD-(L)1 Inhibitors in Select Advanced Solid TumorsWithdrawnNCT05234606Phase 1/2
• RM-1995 Photoimmunotherapy, as Monotherapy or Combined With Pembrolizumab, in Patients With Advanced CuSCC and HNSCCWithdrawnNCT05220748Phase 1
• Study of Neoadjuvant Nivolumab or Placebo Plus Chemotherapy Followed by Surgery and Adjuvant Treatment in Subjects With Resectable ESCCStatus unknownNCT05213312Phase 2/3
• Clinical Evaluation of Detection of High Risk HPV in UrineStatus unknownNCT05210348
• THIO Sequenced With Cemiplimab in Advanced NSCLCActive, not recruitingNCT05208944Phase 2
• The Optimization of Antiemetic Regimen for C-RINV in LA-HNSCCsStatus unknownNCT05202275Phase 2
• Tumor Recurrence After Abdominal-perineal Amputation in Squamous Cell Carcinoma of the AnusCompletedNCT05201105
• Correlation Between the Efficacy of Neoadjuvant Chemotherapy Combined With Immunotherapy of Operable Thoracic Esophageal Squamous Cell Carcinoma and the Metabolites of Intestinal FloraStatus unknownNCT05199649Not applicable
• ASP-1929 Photoimmunotherapy (PIT) Study in Patients With Recurrent Head/Neck CancerActive, not recruitingNCT05182866Phase 2
• Effectiveness of Neoadjuvant Chemotherapy Combined With PD-1 Monoclonal Antibody in the Treatment of Operable Esophageal Squamous Cell CarcinomaStatus unknownNCT05174325Phase 2
• Trastuzumab and Standard Treatment With Chemo- and Immunotherapy as First Line Treatment for HER2 Positive Esophageal Squamous Cell Carcinoma PatientsStatus unknownNCT05170256Phase 2
• JMT101 Combined With Afatinib in Patients With Advanced Esophageal Squamous Cell Carcinoma After Standard TherapyStatus unknownNCT05164848Phase 1
• Correlation of Fecal Microbiome and Its Metabolites With Outcome of Radiotherapy in Head and Neck CarcinomaActive, not recruitingNCT05156177
• Association of Salivary Amino Acid Level With OSCC Identified By Liquid Chromatography Mass SpectroscopyStatus unknownNCT05150509
• Study to Evaluate Safety and Efficacy of TJ107 Combine With PD-1 in Patients With Solid TumorsActive, not recruitingNCT05145907Phase 2
• Acupuncture for Dysphagia in Head and Neck Squamous Cell CarcinomaStatus unknownNCT05143268
• Sintilimab Combined With Chemotherapy and SBRT in Limited Metastatic Head and Neck Squamous Cell Carcinoma (LM-HNSCC)Status unknownNCT05136768Phase 2
• Neo-NTP-CRT for Locally Advanced ESCCStatus unknownNCT05130684Phase 2
• 4-Point Therapy Response Score With PET/CT for Anal Squamous Cell CancerCompletedNCT05130073
• A Retrospective Analysis to Evaluate Long Term Outcomes of SCC Patients Previously Treated With Alpha DaRTCompletedNCT05125354
• A Study of Treatment Patterns and Clinical Outcomes in First Line Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck (1L R/M SCCHN) Participants in EuropeCompletedNCT05123950
• Salvage Immunotherapy and Chemotherapy in Esophageal Squamous Cell Carcinoma Patients Nonresponding to Initial Neoadjuvant ChemoradiotherapyStatus unknownNCT05103501Phase 2
• Tolerability and Efficacy of UV1 Vaccine in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Planned for First-line Treatment With PembrolizumabStatus unknownNCT05075122Phase 2
• Study of Afatinib in Advanced Cutaneous Squamous Cell CarcinomaActive, not recruitingNCT05070403Phase 2
• A Study of Nivolumab in Participants With Squamous Cell Carcinoma of the Head & Neck (SCCHN) - Patient Reported Outcomes (PRO)CompletedNCT05068609
• ANAL PRECANCEROUS LESIONS IN HIGH-RISK PATIENTS.Status unknownNCT05060640
• Comparing Two Surveillance Approaches for People Who Have Received Treatment for HPV-associated Head and Neck Cancer and Show No Signs of DiseaseActive, not recruitingNCT05048459Not applicable
• Anlotinib Combined With TQB2450 (PD-L1 Inhibitor) in the Treatment of Advanced Esophageal Squamous Cell Carcinoma(ESCC)Active, not recruitingNCT05038813Phase 2
• Atezolizumab Immunotherapy, in Immunotherapy Naive Patients With Urinary Tract Squamous Cell Carcinoma (UTSCC).Status unknownNCT05038657Phase 2

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