An interventional study of Core Decompression and Platelet rich plasma (PRP) in Avascular Necrosis of the Femoral Head, sponsored by Ain Shams University. Completed at 1 site in Egypt. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-11-06.
Sponsored by Ain Shams University · Not applicable, Interventional, and Treatment
This study aims to compare core decompression, a classic technique used for the treatment of avascular necrosis of the femoral head, versus core decompression augmented with PRP instillation, and how it affects the outcome of the disease.
A total of 30 hips with stage 1 or 2 avascular necrosis of the femoral head according to the Arlet and Ficat classification were included in the study. Using randomized allocation, 15 hips underwent core decompression alone and 15 hips underwent core decompression with Platelet-Rich-Plasma instillation.
65 studies on the registry are indexed under Femur Head Necrosis; 16 are open to participants now.
This study's enrollment of 30 is below the median of 60 across 36 interventional studies indexed under Femur Head Necrosis.
Browse Femur Head Necrosis studies →Ain Shams University is the lead sponsor of 1,950 studies on the registry; 429 are open to participants now.
Of its 35 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
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You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
This is the classic gold standard technique used for these types of patients
Procedure: Core Decompression
This is an augmented form of core decompression which includes a biological enhancement by adding PRP instillation
Procedure: Core Decompression · Biological: Platelet rich plasma (PRP)
The classic technique used to manage these types of cases
Augmenting Core Decompression with PRP instillation as a biological enhancement to a classic technique
Harris Hip Score
A numerical assessment measurement of hip function and pain on a scale of 0-100
Time frame: 18 months post intervention
Modified Kerboul Angle
A radiological assessement measurement of femoral head necrosis by measuring angles from serial MRI scans.
Time frame: 18 months post intervention
Conversion to Total Hip Arthroplasty
A real world indicator of joint preservation showing whether patients were satisfied with the outcome or had to resort to hip replacement surgery.
Time frame: 18 months post intervention
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Nov 2026. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Platelet rich plasma