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CompletedNCT07919184Updated Nov 5, 2026

Eccentric Exercise Versus Neurodynamic Sliding Technique for Hamstring Flexibility and Lower-Limb Strength

An interventional study of The hamstring eccentric exercises and The neurodynamic sliding technique in Hamstring Tightness, sponsored by King Saud University. Completed at 1 site in India. Open to female participants aged 18 Years to 25 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-05.

Sponsored by King Saud University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 2 years 2 months after the study started (first participant enrolled Aug 2024, registered Oct 2026).
Updated Nov 5, 2026Newly registeredGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
42
Allocation
Randomized
Ages
18 Years to 25 Years
Sex
Female
01

Study summary

This randomized comparative trial evaluated the effects of a six-week, supervised intervention comparing eccentric exercise to the neurodynamic sliding technique in 42 sedentary young women with hamstring tightness. Both interventions were completed without adverse events and produced significant improvements in hamstring flexibility (active knee extension) and lower-limb strength. Although the eccentric exercise group achieved significantly greater strength gains and greater flexibility improvements over time compared to the neurodynamic sliding group, the overall between-group differences in flexibility across time points were not statistically significant and were confounded by baseline imbalances. Consequently, while both approaches are effective for this population, eccentric exercise demonstrated greater overall benefits, though the between-group flexibility advantages warrant cautious interpretation.

02

Conditions studied

  • Hamstring Tightness

Keywords

  • Hamstring tightness
  • eccentric exercise
  • neurodynamic sliding technique
  • flexibility
  • muscle strength
03

In context

Lead sponsor

King Saud University is the lead sponsor of 169 studies on the registry; 21 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 25 Years
Sexes eligible
Female
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Sedentary young women
  • 18 to 25 years
  • Absence of major metabolic comorbidity,
  • Active knee extension loss of at least 20 degrees,
  • Unilateral or bilateral hamstring tightness with full knee range of motion

Exclusion criteria

Exclusion Criteria:

  • Prior injury,
  • Neurological dysfunction,
  • Spinal pathology,
  • Regular sports participation;
  • A history of musculotendinous hamstring injury;
  • A history of lumbar disc herniation;
  • Limited joint mobility of the hip, knee, or ankle,
  • Rheumatoid arthritis;
  • Anterior cruciate ligament tear without surgical correction;
  • Abnormal psychological conditions;
  • Radiating low back pain;
  • Congenital, traumatic, or acquired (pathological or infective) spinal conditions;
  • ;
  • Neck trauma.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Cancer (malignancy)

Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.

Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
42 participants (actual)

Study arms

  • Experimental
    The eccentric exercise group

    In the eccentric exercise group the participants performed a TheraBand-assisted eccentric hamstring exercise three times weekly for a total duration of 6 weeks.

    Other: The hamstring eccentric exercises

  • Active comparator
    The neurodynamic sliding technique group

    In the neurodynamic sliding technique group the participants performed a a seated slump-based neurodynamic sliding sequence three times weekly for a total duration of 6 weeks.

    Other: The neurodynamic sliding technique

Interventions

  • OtherThe hamstring eccentric exercises

    To perform hamstring eccentric exercises in supine with the lower extremities fully extended, a 1-meter TheraBand was wrapped around the foot and held in both hands. Participants actively flexed the hip while resisting eccentrically with the hamstrings for about 5 seconds, then slowly extended the hip.

  • OtherThe neurodynamic sliding technique

    To perform the neurodynamic sliding technique, participants sat with a slouched posture and hands behind their backs, then alternated cervical extension with ankle dorsiflexion and knee extension, followed by cervical flexion with ankle plantarflexion and knee flexion.

06

What researchers measure

Primary outcomes

  1. Active Knee Extension Test

    Participants lay supine with the hip and knee flexed to 90 degrees, actively extended the knee while maintaining hip position, and the popliteal angle was calculated as 180 degrees minus the measured knee extension angle, with lower values indicating greater flexibility. Normal Range for this outcome is 15 degrees - 25 degrees. Lower values indicate better outcome.

    Time frame: This outcome was measured before the initiation of the 6-week intervention and at the end of the 6-week intervention.

  2. Lower-limb strength

    Participants stood on the platform of Back-Leg-Chest dynamometer, with slight knee flexion, grasped the handle at knee level, and performed a maximal isometric lift for three seconds. Normal ranges: 220 to 330 lbs. Higher values indicate better outcome.

    Time frame: This outcome was measured before the initiation of the 6-week intervention and at the end of the 6-week intervention.

07

Study locations

1 site
  • AWH Special College
    Calicut, Kerala, India
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

1 registry update since Sep 25, 2026
Registered
First appeared on the registry. No changes since
Nov 5, 2026
Show all 1 update
  1. Nov 5, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07919184
Responsible party
Masood Khan (Principal Investigator, King Saud University) — Principal investigator
First posted
Nov 5, 2026
Start date
Aug 7, 2024
Primary completion
Jan 10, 2025
Completion
Feb 18, 2025
Last update
Nov 5, 2026

Study contacts

Kavitha Jayaraman
principal investigator · AWH Special College

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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