An observational study in Glycogen Storage Disease, sponsored by Peking Union Medical College Hospital. Recruiting at 1 site in China. Open to participants aged 3 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-02.
Sponsored by Peking Union Medical College Hospital · Observational
The goal of this observational study is to learn about cognitive function and brain imaging findings in people with glycogen storage disease (GSD). The main questions it aims to answer are:
Participants will:
36 studies on the registry are indexed under Glycogen Storage Disease; 13 are open to participants now.
This study's planned enrollment of 318 is above the median of 85 across 16 observational studies indexed under Glycogen Storage Disease.
Browse Glycogen Storage Disease studies →Peking Union Medical College Hospital is the lead sponsor of 1,155 studies on the registry; 475 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
We enroll individuals diagnosed with glycogen storage disease who are able to complete cognitive assessments and brain MRI, and healthy volunteers matched for age and sex.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
GSD group:
Control group:
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Patients with glycogen storage disease
Healthy controls
Cognitive impairment
IQ\<70 assessed by cognitive tests (Wechsler Intelligence Scale for patients younger than 16 years old, Raven's Progressive Matrices for patients older than 16)
Time frame: Baseline, and follow-up through study completion, an average of 1 year
Cerebral Blood Flow
Cerebral blood flow quantified from arterial spin labeling (ASL) MRI
Time frame: Baseline, and follow-up through study completion, an average of 1 year
Cerebral Small Vessel Disease
Presence of MRI Markers of Cerebral Small Vessel Disease, including white matter hyperintensities, lacunes, cerebral microbleeds, and enlarged perivascular spaces
Time frame: Baseline, and follow-up through study completion, an average of 1 year
Brain Volume
Total and regional brain volumes quantified from three-dimensional T1-weighted MRI
Time frame: Baseline, and follow-up through study completion, an average of 1 year
Brain Metabolites
Brain metabolite levels (NAA, Cho, mI, Cr) measured by magnetic resonance spectroscopy in specified brain regions
Time frame: Baseline, and follow-up through study completion, an average of 1 year
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
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