An interventional study of Lavender Essential Oil Inhalation in Anxiety and Coronary Angiography (CAG), sponsored by Betul Bayrak. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-30.
Sponsored by Betul Bayrak · Not applicable, Interventional, and Supportive care
This study evaluated the effects of lavender essential oil inhalation on anxiety, pulse rate, and blood pressure in patients undergoing coronary angiography. Participants were assigned to either the lavender inhalation group or the routine care control group in a 1:1 ratio by drawing lots. In the intervention group, three drops of lavender essential oil were applied to cotton placed in a small container approximately 30-40 cm from the patient. Inhalation continued during the waiting period before coronary angiography. The control group received routine care without aromatherapy. Anxiety was measured using the State Anxiety Inventory, and pulse rate and systolic and diastolic blood pressure were measured before the intervention and immediately after patients returned to the unit following coronary angiography.
This randomized controlled study evaluated the effects of lavender essential oil inhalation on state anxiety, pulse rate, and systolic and diastolic blood pressure in patients undergoing coronary angiography at a university hospital in Türkiye. Participants were randomly assigned in a 1:1 ratio to the lavender inhalation group or the routine care control group using a drawing-of-lots method.
Baseline assessments were performed approximately 30 minutes before coronary angiography. Systolic and diastolic blood pressure and pulse rate were measured, followed by administration of the State Anxiety Inventory. This 20-item questionnaire measures current anxiety, with total scores ranging from 20 to 80; higher scores indicate greater anxiety. The researcher read each item aloud and recorded the participant's response.
Following baseline assessment, participants in the intervention group received passive inhalation of lavender essential oil (Lavandula angustifolia). Approximately 2-3 g of cotton was placed in a small container, and three drops of lavender essential oil were applied to the cotton. The container was positioned on the bedside table approximately 30-40 cm from the participant, with the distance adjusted within this range according to individual comfort. Inhalation continued throughout the waiting period and ended when the participant was transferred for coronary angiography. Both researchers had received certified training in aromatherapy.
Participants in the control group received routine care in the coronary angiography unit without lavender inhalation or an additional study intervention intended to reduce anxiety.
Immediately after participants returned to the unit following coronary angiography, blood pressure and pulse rate were measured again, followed by a second administration of the State Anxiety Inventory using the same procedure as at baseline. Changes in state anxiety and physiological measurements were compared between groups using two-way repeated-measures analysis of variance to assess the effects of group, time, and the group-by-time interaction.
7,201 studies on the registry are indexed under Anxiety Disorders; 1,682 are open to participants now.
This study's enrollment of 80 is close to the median of 80 across 6,057 interventional studies indexed under Anxiety Disorders.
Browse Anxiety Disorders studies →This is the only study on the registry with Betul Bayrak as lead sponsor.
Compared within Anxiety Disorders, the registry's first condition term, which may not be this study's main condition. Counted across the registry records on this site, refreshed daily. How we classify →
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Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Other: Lavender Essential Oil Inhalation
Three drops of lavender essential oil (Lavandula angustifolia) were applied to approximately 2-3 g of cotton placed in a small container. The container was positioned on the bedside table approximately 30-40 cm from the participant, with the distance adjusted within this range for comfort. Following baseline assessment approximately 30 minutes before coronary angiography, participants passively inhaled the lavender aroma during the waiting period. Exposure ended when the participant was transferred for the procedure. Routine care continued throughout.
Change in State Anxiety Inventory Score From Baseline to After Coronary Angiography
Time frame: Baseline (approximately 30 minutes before coronary angiography) and immediately after returning to the unit following coronary angiography.
Change in Systolic Blood Pressure From Baseline to After Coronary Angiography
Time frame: Baseline (approximately 30 minutes before coronary angiography) and immediately after returning to the unit following coronary angiography.
Change in Diastolic Blood Pressure From Baseline to After Coronary Angiography
Time frame: Baseline (approximately 30 minutes before coronary angiography) and immediately after returning to the unit following coronary angiography.
Change in Pulse Rate From Baseline to After Coronary Angiography
Time frame: Baseline (approximately 30 minutes before coronary angiography) and immediately after returning to the unit following coronary angiography.
Plan to share: No
No publications or documents are linked to this record.
Ran from Apr 2024 to primary completion in May 2024, 1 month.
Of 3,836 non-industry interventional studies with no phase under Anxiety Disorders, half reached primary completion within 12 months of starting (the median), counting those still running; a quarter within 5 and three quarters within 28. This study's 1 month is below that.
Counting every sponsor, half of 3,938 studies reached it within 12 months; a quarter within 5 and three quarters within 28.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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