An interventional study of Cyriax Approach with Mobilization with movement and Cyriax Approach without Mobilization with Movement in Rotator Cuff Tendinopathy, sponsored by University of Management and Technology Lahore. Active, not recruiting at 1 site in Pakistan. Open to participants aged 30 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-10-26.
Sponsored by University of Management and Technology Lahore · Not applicable, Interventional, and Treatment
This randomized clinical trial compares the effects of the Cyriax approach (deep transverse friction massage) with and without Mulligan Mobilization with Movement (MWM) on pain, range of motion and disability in patients with shoulder restriction due to rotator cuff tendinopathy. Thirty-eight patients (19 per group) will be recruited by non-probability convenience sampling and randomly allocated to two groups. Both groups will receive laser therapy and conventional physiotherapy; 12 sessions over 4 weeks (3 sessions per week). Outcomes (NPRS, SPADI, Angulus Pro smartphone application) will be measured at baseline and at the 4th week and analyzed using SPSS version 24.
725 studies on the registry are indexed under Shoulder Pain; 152 are open to participants now.
This study's planned enrollment of 38 is below the median of 60 across 577 interventional studies indexed under Shoulder Pain.
Browse Shoulder Pain studies →University of Management and Technology Lahore is the lead sponsor of 7 studies on the registry; 5 are open to participants now.
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Age 30 to 65 years. Both male and female genders. Symptoms in acute (up to 4 weeks) or sub-acute stage (4-6 weeks). Shoulder pain related to the rotator cuff or clinically documented rotator cuff tendinopathy.
Pain intensity of 4-6 on the Numeric Pain Rating Scale (NPRS). Limited range of motion of the shoulder, either passive or active. Positive in any two or three impingement/tendinopathy tests: Neer's test, Hawkins-Kennedy test, painful arc test, empty can test and external rotation resistance test.
Unilateral involvement of the shoulder
Exclusion Criteria:
Previous cervical spine or shoulder surgery. Referred pain from the cervical spine or cervical radiculopathy. Other conditions affecting the shoulder joint complex: fractures or dislocations, severe osteoarthritis of the glenohumeral or acromioclavicular joint, adhesive capsulitis, shoulder stiffness and glenohumeral instability.
Full-thickness rotator cuff tear or signs that surgery is necessary. Musculoskeletal or systemic inflammatory conditions such as severe osteoarthritis or rheumatoid arthritis.
Corticosteroid injections within the last six weeks to three months. Involvement of both shoulders. Concurrent manual therapy or physiotherapy
Cyriax approach (deep transverse friction massage, 10-12 minutes per session) plus Mulligan Mobilization with Movement (sustained posterolateral glide of the humeral head during pain-free active shoulder movement; 3 sets of 10 repetitions with 30-second rest), together with laser therapy and conventional treatment, 3 sessions per week for 4 weeks
Other: Cyriax Approach with Mobilization with movement
Cyriax approach (deep transverse friction massage, 10-12 minutes per session) together with laser therapy and conventional treatment, 3 sessions per week for 4 weeks.
Other: Cyriax Approach without Mobilization with Movement
Cyriax approach (deep transverse friction massage, 10-12 minutes per session) plus Mulligan Mobilization with Movement (sustained posterolateral glide of the humeral head during pain-free active shoulder movement; 3 sets of 10 repetitions with 30-second rest), together with laser therapy and conventional treatment, 3 sessions per week for 4 weeks.
Cyriax approach (deep transverse friction massage, 10-12 minutes per session) together with laser therapy and conventional treatment, 3 sessions per week for 4 weeks.
Numeric Pain Rating Scale
11-point self-reported scale: 0 representing no pain and 10 the most severe pain (1-3 mild, 4-6 moderate, 7-10 severe pain). Pain is rated at rest and during activity. Reported ICC 0.74-0.92; MCID about 2-2.5 points
Time frame: Baseline and after 4 weeks
Shoulder Pain and Disability Index
13-item self-administered questionnaire with a pain subscale (5 items) and a disability subscale (8 items); each item scored 0-10 and total converted to a percentage, higher scores indicating greater disability. Cronbach's alpha about 0.94, test-retest ICC 0.89-0.91; MCID 8-25 points
Time frame: Baseline and after 4 weeks
Smartphone Application
Used to measure shoulder range of motion (flexion, extension, abduction, adduction, internal and external rotation) from images or video frames; reported test-retest reliability 0.852-0.856
Time frame: Baseline and after 4 weeks
Plan to share: Yes — The results data collected, de-identified individual participant data will be shared.
Supporting information: Study protocol, Statistical analysis plan, Informed consent form
Time frame: 6 months after the publication of the manuscript.
Access criteria: The data can be requested from the corresponding author.
Started Oct 2026 (actual). Primary completion is estimated for Dec 2026, 2 months after the start.
Of 327 non-industry interventional studies with no phase under Shoulder Pain, half reached primary completion within 10 months of starting (the median), counting those still running; a quarter within 4 and three quarters within 27. This study's planned 2 months is below that.
Counting every sponsor, half of 336 studies reached it within 11 months; a quarter within 5 and three quarters within 27.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is active, not recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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University of Management and Technology Lahore