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CompletedNCT07889102Updated Oct 22, 2026

Impact of Telepharmacy on Hemodialysis Outcomes

An interventional study of Routine Standard Care and Telepharmacy Intervention in Anemia and Hemodialysis, sponsored by Damanhour University. Completed at 2 sites in Egypt. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-22.

Sponsored by Damanhour University · Not applicable, Interventional, and Supportive care

From the registry’s dates

  • Registered 1 year 6 months after the study started (first participant enrolled Dec 2024, registered Jun 2026).
Updated Oct 22, 2026Newly registeredGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
101
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

This study looked at whether regular follow-up by pharmacists through phone calls (telepharmacy) can help improve the treatment of anaemia in patients undergoing haemodialysis.

Anaemia is very common in patients with kidney disease and can cause fatigue, weakness, and an increased risk of heart problems. It is usually treated with medications such as erythropoietin (EPO), but managing the correct dose and ensuring patients follow treatment can be challenging. In this study, patients were divided into two groups. One group received standard care, while the other group received additional support from pharmacists through regular phone calls. During these calls, pharmacists helped patients understand their medications, encouraged adherence, monitored symptoms, and worked with doctors to adjust treatment when needed.

02

Conditions studied

  • Anemia
  • Hemodialysis

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03

In context

Anemia

1,768 studies on the registry are indexed under Anemia; 244 are open to participants now.

This study's enrollment of 101 is close to the median of 96 across 1,318 interventional studies indexed under Anemia.

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Lead sponsor

Damanhour University is the lead sponsor of 78 studies on the registry; 4 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Adults aged 18 years or older.
  • Confirmed diagnosis of chronic kidney disease (CKD).
  • Receiving maintenance hemodialysis at one of the participating centers.
  • Receiving regular hemodialysis sessions.
  • Anemia requiring treatment with erythropoiesis-stimulating agents (ESAs).
  • Baseline hemoglobin level \<11.5 g/dL.
  • Able to communicate by telephone to participate in the telepharmacy intervention.
  • Willing and able to provide written informed consent.
  • Willing to comply with all study procedures and follow-up assessments.

Exclusion criteria

Exclusion Criteria:

  • Unwilling or unable to provide informed consent.
  • Significant cognitive impairment or psychiatric illness that could interfere with study participation.
  • No reliable telephone access for telepharmacy follow-up.
  • Unstable clinical condition requiring emergency or intensive care.
  • Severe comorbid conditions expected to limit short-term survival.
  • Not receiving regular maintenance hemodialysis.
  • Incomplete baseline clinical or laboratory data.
  • Inability or unwillingness to complete the planned follow-up period
05

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
101 participants (actual)

Study arms

  • Active comparator
    Standard Care Control Group

    Participants assigned to this arm received routine hemodialysis care according to standard clinical practice without additional telepharmacy support. This included regular physician follow-up, laboratory monitoring, and medication management as determined by the treating healthcare team. No structured pharmacist-led remote monitoring or scheduled telecommunication-based interventions were provided.

    Other: Routine Standard Care

  • Experimental
    Telepharmacy Intervention Group

    Participants assigned to this arm received routine maintenance hemodialysis care in addition to a structured telepharmacy intervention delivered by trained clinical pharmacists over a 5-month period. The intervention included scheduled telephone follow-up, medication review, adherence assessment, individualized counseling, monitoring of laboratory results, identification and resolution of drug-related problems, and collaboration with treating physicians to optimize erythropoiesis-stimulating agent (ESA) therapy and overall medication management.

    Other: Routine Standard Care · Behavioral: Telepharmacy Intervention

Interventions

  • OtherRoutine Standard Care

    Participants assigned to the Routine Standard Care intervention received routine maintenance hemodialysis care according to the participating hospitals' standard clinical practice. Standard care included regular nephrologist follow-up, routine laboratory monitoring (including hemoglobin and other relevant biochemical parameters), prescription and adjustment of erythropoiesis-stimulating agents (ESAs) and other medications as clinically indicated, and conventional nursing and dialysis care. Medication management and treatment decisions were made during routine clinical visits. Unlike the experimental arm, participants did not receive the structured telepharmacy intervention, including scheduled telephone consultations, proactive medication review, adherence counseling, pharmacist-initiated remote monitoring, or pharmacist-led therapeutic follow-up.

  • BehavioralTelepharmacy Intervention

    Pharmacist-led remote care including scheduled telephone follow-up, medication review, adherence assessment, individualized counseling, monitoring of laboratory results, identification and resolution of drug-related problems, and collaboration with physicians to optimize erythropoiesis-stimulating agent (ESA) therapy and overall medication management. Participants continued to receive routine standard care throughout the study in addition to the telepharmacy intervention.

06

What researchers measure

Primary outcomes

  1. Change in hemoglobin (Hb) level

    Time frame: 5 months

Secondary outcomes

  1. Change in erythropoietin dose

    Time frame: 5 months

Other outcomes

  1. Number of identified drug-related problems

    Time frame: 5 months

07

Study locations

2 sites
  • Menoufia University Hospital
    Shibīn al Kawm, Menofia 32511, Egypt
  • Menoufia University Hospital
    Shibīn al Kawm, Menoufia 32511, Egypt
08

References and documents

Related links

Individual participant data

Plan to share: No

09

Updates

1 registry update since Sep 25, 2026
Registered
First appeared on the registry. No changes since
Oct 22, 2026
Show all 1 update
  1. Oct 22, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07889102
Lead sponsor
Damanhour University
Responsible party
Sponsor
First posted
Oct 22, 2026
Start date
Dec 1, 2024
Primary completion
Apr 1, 2025
Completion
Apr 30, 2025
Last update
Oct 22, 2026

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in May 2024. You cannot join it, but the record below documents what was studied.

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