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Not yet recruitingNCT07887841Updated Oct 21, 2026

Effects of Probiotics on Skin Health in Healthy Women

An interventional study of Probiotics and Placebo in Skin Aging, Dry Skin, sponsored by Probi AB. Not yet recruiting at 1 site in United Kingdom. Open to female participants aged 35 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-10-21.

Sponsored by Probi AB · Not applicable, Interventional, and Prevention

Updated Oct 21, 2026Newly registeredGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
140
Allocation
Randomized
Ages
35 Years to 45 Years
Sex
Female
01

Study summary

The effect of probiotics on skin health in healthy women with dry to very dry facial skin.

02

Conditions studied

  • Skin Aging, Dry Skin

Keywords

  • probiotics, dry skin
  • wrinkles
03

In context

Lead sponsor

Probi AB is the lead sponsor of 22 studies on the registry; 2 are open to participants now.

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Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
35 Years to 45 Years
Sexes eligible
Female
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Female, of self-reported Caucasian ethnicity, aged 35 to 45 years at the time of informed consent
  • Fitzpatrick skin type II-IV
  • Mean MoistureMeterSC value of ≤30 obtained at the Baseline Visit before randomisation
  • Generally healthy

Exclusion criteria

Exclusion Criteria:

  • Significant facial dermatological condition that may interfere with study assessments
  • Uncontrolled or clinically significant medical condition that may compromise participant safety or interpretation of study outcomes
  • Known allergy, intolerance or hypersensitivity to any active ingredient, excipient or component of the study product or placebo
  • Use of prohibited medications, nutritional supplements or cosmetic/dermatological procedures
  • Current participation in another interventional clinical study, or participation in another interventional study within the previous 30 days.
  • Lifestyle, skincare or cosmetic factors likely to interfere with study assessments or interfere with instrumental or imaging assessment
  • Pregnant, breastfeeding or planning pregnancy during the study period.
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Quadruple (Participant, Care provider, Investigator, Outcomes assessor)
Enrollment
140 participants (estimated)

Study arms

  • Active comparator
    Probiotics

    Dietary Supplement: Probiotics

  • Placebo comparator
    Placebo

    Dietary Supplement: Placebo

Interventions

  • Dietary supplementProbiotics

    Probiotics

  • Dietary supplementPlacebo

    Placebo

06

What researchers measure

Primary outcomes

  1. PRIMOS CR crow's-feet wrinkle depth

    Time frame: 12 weeks

07

Study locations

1 site
  • Sequential Skin Ltd
    Babraham, CB22 3AT, United Kingdom
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

1 registry update since Sep 25, 2026
Registered
First appeared on the registry. No changes since
Oct 21, 2026
Show all 1 update
  1. Oct 21, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07887841
Lead sponsor
Probi AB
Responsible party
Sponsor
First posted
Oct 21, 2026
Start date
Oct 2026 (estimated)
Primary completion
May 2027 (estimated)
Completion
May 2027 (estimated)
Last update
Oct 21, 2026

Study contacts

Albert Dashi, PhD
Contact
albert@sequential.bio
+44 7852591629

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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Discussion

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