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Active, not recruitingNCT07884552Updated Oct 20, 2026

Virtual Reality Vs Postural Control Training in Children With Cerebral Palsy

An interventional study of Virtual reality and Postural control training in Children With Hemiplegic cp, sponsored by Amira Mahmoud Abdelkader Mohamed. Active, not recruiting at 1 site in Egypt. Open to participants aged 8 Years to 10 Years. Per ClinicalTrials.gov, last updated 2026-10-20.

Sponsored by Amira Mahmoud Abdelkader Mohamed · Not applicable, Interventional, and Treatment

Updated Oct 20, 2026Newly registeredGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
70
Allocation
Randomized
Ages
8 Years to 10 Years
Sex
All
01

Study summary

The goal of this clinical trial is to learn if there is difference between the effect of virtual reality and postural control training on balance and gait in children with hemiplegic cerebral palsy. The main questions it aims to answer are:

  • Whether there is an effect of Virtual reality training on balance and gait in children with hemiplegic cerebral palsy?
  • Whether there is an effect of Biodex training as a method of postural control on balance and gait in children with hemiplegic cerebral palsy? Researchers will compare the effect of Virtual reality and Biodex as a method of postural control training on balance and gait in children with hemiplegic CP.

Participants will:

  • Receive the intervention for 2 months.
  • Visit the clinic 3 times per week for sessions
02

Conditions studied

  • Children With Hemiplegic cp

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Keywords

  • Virtual reality
  • Postural control
  • Balance
  • Gait
  • Cerebral palsy
  • Children
03

In context

Cerebral Palsy

1,891 studies on the registry are indexed under Cerebral Palsy; 439 are open to participants now.

This study's planned enrollment of 70 is above the median of 34 across 1,396 interventional studies indexed under Cerebral Palsy.

Browse Cerebral Palsy studies →

Lead sponsor

This is the only study on the registry with Amira Mahmoud Abdelkader Mohamed as lead sponsor.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
8 Years to 10 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. They are diagnosed with hemiplegic cerebral palsy.
  2. Their ages ranged from 8-10 years.
  3. Degree of spasticity according to Modified Ashworth Scale will be ranged from grade 1 and 1+.
  4. The levels of gross motor function will be between level I and II according to Growth Motor Functional Classification System (GMFCS) for all children.
  5. Children's height will be minimum one meter (lower limits of height needed by the Biodex Balance System).
  6. Children will be able to follow verbal commands.

Exclusion criteria

Exclusion Criteria:

  1. Visual or auditory problems.
  2. Contractures of the lower limbs.
  3. Seizures or epilepsy.
  4. Children who received Botulinum toxin injections for the past 6 months.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Quadruple (Participant, Care provider, Investigator, Outcomes assessor)
Enrollment
70 participants (estimated)

Study arms

  • Experimental
    Group A: Virtual reality

    Device: Virtual reality

  • Experimental
    Group B: Postural control training

    Device: Postural control training

Interventions

  • DeviceVirtual reality

    Wii fit plus will be used for balance training, which consist of a wireless handheld pointing device, the detection of movement and acceleration being in three dimensions by a motion sensor attached to a television. The virtual image is seen on the television screen that mimics the participant's movements. These games encourage the interaction of participants to play repetitively (Lohse, et al.,2014).

  • DevicePostural control training

    The Biodex Stability System (BSS), is a unique balance assessment and training device. It is designed to assess the neuromuscular control and to stimulate joint mechanoreceptors (Hsue et al.,2009). It measures the ability of the subject to control the platform's angle of tilt, which is noted as a stability index and has high acceptable reliability (Hinman, 2009). It consists of a movable balance platform that provides up to 20 degrees of surface tilt in a360-degree range of motion. the platform is free to move about the AP and ML axes simultaneously (Figure 8) (Akhbari et al., 2007).

06

What researchers measure

Primary outcomes

  1. Stance time in seconds

    Time frame: 2 months

  2. Walking speed in meter er seconds

    Time frame: 2 months

  3. Step length in centimeters

    Time frame: 2 months

  4. Center of balance in percentage of weight shift

    Time frame: 2 months

07

Study locations

1 site
  • faculty of physical therapy-Cairo university
    Cairo, Egypt
08

References and documents

Publications

  • Morone G, Tramontano M, Iosa M, Shofany J, Iemma A, Musicco M, Paolucci S, Caltagirone C. The efficacy of balance training with video game-based therapy in subacute stroke patients: a randomized controlled trial. Biomed Res Int. 2014;2014:580861. doi: 10.1155/2014/580861. Epub 2014 May 5. PubMed 24877116 ↗
  • Juras G, Słomka K, Fredyk A, Sobota G, Bacik B. (2008). Evaluation of the limits of stability (LOS) balance test. J Hum Kinet.;19(1):39-52; doi:10.2478/v10078-008-0003-0.
  • Arnoni JLB, Pavao SL, Dos Santos Silva FP, Rocha NACF. Effects of virtual reality in body oscillation and motor performance of children with cerebral palsy: A preliminary randomized controlled clinical trial. Complement Ther Clin Pract. 2019 May;35:189-194. doi: 10.1016/j.ctcp.2019.02.014. Epub 2019 Feb 25. PubMed 31003657 ↗
  • Jessica Cheunga, Melissa Marona, Sandy Tatlaa,b and Tal Jarusa.(2013). Virtual reality as balance rehabilitation for children with brain injury: A case study. Technology and Disability 25 (2013) 207-219 207; DOI 10.3233/TAD-130383
  • Jelsma J, Pronk M, Ferguson G, Jelsma-Smit D. The effect of the Nintendo Wii Fit on balance control and gross motor function of children with spastic hemiplegic cerebral palsy. Dev Neurorehabil. 2013;16(1):27-37. doi: 10.3109/17518423.2012.711781. Epub 2012 Oct 3. PubMed 23030836 ↗
  • Hsue BJ, Miller F, Su FC. The dynamic balance of the children with cerebral palsy and typical developing during gait. Part I: Spatial relationship between COM and COP trajectories. Gait Posture. 2009 Apr;29(3):465-70. doi: 10.1016/j.gaitpost.2008.11.007. Epub 2008 Dec 25. PubMed 19111469 ↗
  • Hinman M. (2009): Factors affecting reliability of the Biodex Balance System: A summary of four studies. J Sport Rehabil; 9:240-252.
  • Hawker GA, Mian S, Kendzerska T, French M. Measures of adult pain: Visual Analog Scale for Pain (VAS Pain), Numeric Rating Scale for Pain (NRS Pain), McGill Pain Questionnaire (MPQ), Short-Form McGill Pain Questionnaire (SF-MPQ), Chronic Pain Grade Scale (CPGS), Short Form-36 Bodily Pain Scale (SF-36 BPS), and Measure of Intermittent and Constant Osteoarthritis Pain (ICOAP). Arthritis Care Res (Hoboken). 2011 Nov;63 Suppl 11:S240-52. doi: 10.1002/acr.20543. No abstract available. PubMed 22588748 ↗
  • Hatem Abdal-Mohsen Emara; Tarek Mohamed El-Gohary; Osama Ahmed Khaled. (2016). Using Biodex balance training system to improve postural control in spastic diplegic cerebral palsy children: A biomechanical perspective. International Journal of Therapies & Rehabilitation Research; 5 (5):220-226. https://doi.org/10.5455/ijtrr.000000210
  • Gracies JM. Pathophysiology of spastic paresis. I: Paresis and soft tissue changes. Muscle Nerve. 2005 May;31(5):535-51. doi: 10.1002/mus.20284. PubMed 15714510 ↗
  • Gage JR. Gait analysis. An essential tool in the treatment of cerebral palsy. Clin Orthop Relat Res. 1993 Mar;(288):126-34. PubMed 8458125 ↗
  • Gorter JW, Rosenbaum PL, Hanna SE, Palisano RJ, Bartlett DJ, Russell DJ, Walter SD, Raina P, Galuppi BE, Wood E. Limb distribution, motor impairment, and functional classification of cerebral palsy. Dev Med Child Neurol. 2004 Jul;46(7):461-7. doi: 10.1017/s0012162204000763. PubMed 15230459 ↗
  • Flynn S, Palma P, Bender A. (2006). Low-tech virtual reality improves function in individuals with central nervous system injury. Journal of Neurological Physical Therapy;30(4): p210-211; DOI: 10.1097/01.NPT.0000281304.16905.61
  • Fang Q, Ghanouni P, Anderson SE, Touchett H, Shirley R, Fang F, Fang C. Effects of Exergaming on Balance of Healthy Older Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Games Health J. 2020 Feb;9(1):11-23. doi: 10.1089/g4h.2019.0016. Epub 2019 Dec 3. PubMed 31800322 ↗
  • Elnaggar RK. Effects of plyometric exercises on muscle-activation strategies and response-capacity to balance threats in children with hemiplegic cerebral palsy. Physiother Theory Pract. 2022 Sep;38(9):1165-1173. doi: 10.1080/09593985.2020.1833389. Epub 2020 Oct 12. PubMed 33044886 ↗
  • El-Gohary TM, Emara HA, Al-Shenqiti A, Hegazy FA. Biodex balance training versus conventional balance training for children with spastic diplegia. J Taibah Univ Med Sci. 2017 Aug 18;12(6):534-540. doi: 10.1016/j.jtumed.2017.07.002. eCollection 2017 Dec. PubMed 31435291 ↗
  • Jelsma D, Geuze RH, Mombarg R, Smits-Engelsman BC. The impact of Wii Fit intervention on dynamic balance control in children with probable Developmental Coordination Disorder and balance problems. Hum Mov Sci. 2014 Feb;33:404-18. doi: 10.1016/j.humov.2013.12.007. Epub 2014 Jan 18. PubMed 24444657 ↗
  • Deutsch JE, Brettler A, Smith C, Welsh J, John R, Guarrera-Bowlby P, Kafri M. Nintendo wii sports and wii fit game analysis, validation, and application to stroke rehabilitation. Top Stroke Rehabil. 2011 Nov-Dec;18(6):701-19. doi: 10.1310/tsr1806-701. PubMed 22436308 ↗
  • Levac DE, Galvin J. When is virtual reality "therapy"? Arch Phys Med Rehabil. 2013 Apr;94(4):795-8. doi: 10.1016/j.apmr.2012.10.021. Epub 2012 Nov 2. PubMed 23124132 ↗
  • De Kegel A, Dhooge I, Peersman W, Rijckaert J, Baetens T, Cambier D, Van Waelvelde H. Construct validity of the assessment of balance in children who are developing typically and in children with hearing impairments. Phys Ther. 2010 Dec;90(12):1783-94. doi: 10.2522/ptj.20100080. Epub 2010 Oct 28. PubMed 21030662 ↗
  • Dean CM, Richards CL, Malouin F. Task-related circuit training improves performance of locomotor tasks in chronic stroke: a randomized, controlled pilot trial. Arch Phys Med Rehabil. 2000 Apr;81(4):409-17. doi: 10.1053/mr.2000.3839. PubMed 10768528 ↗
  • Abd El-Kafy EM, El-Basatiny HM. Effect of postural balance training on gait parameters in children with cerebral palsy. Am J Phys Med Rehabil. 2014 Nov;93(11):938-47. doi: 10.1097/PHM.0000000000000109. PubMed 24901761 ↗
  • Davis RB, Õunpuu S, Tyburski D, Gage JR. (1991). A gait analysis data collection and reduction technique. Hum Mov Sci.;10(5):575-587; doi: 10.1016/0167-9457(91)
  • Clark RA, Bryant AL, Pua Y, McCrory P, Bennell K, Hunt M. Validity and reliability of the Nintendo Wii Balance Board for assessment of standing balance. Gait Posture. 2010 Mar;31(3):307-10. doi: 10.1016/j.gaitpost.2009.11.012. Epub 2009 Dec 11. PubMed 20005112 ↗
  • Chen Y, Fanchiang HD, Howard A. Effectiveness of Virtual Reality in Children With Cerebral Palsy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Phys Ther. 2018 Jan 1;98(1):63-77. doi: 10.1093/ptj/pzx107. PubMed 29088476 ↗
  • Chapman ML, Rubin BR, Gracy RW. The redox state in lymphocytes from patients with rheumatoid arthritis. J Rheumatol. 1986 Oct;13(5):850-2. PubMed 3820194 ↗
  • Brutsch K, Schuler T, Koenig A, Zimmerli L, -Koeneke SM, Lunenburger L, Riener R, Jancke L, Meyer-Heim A. Influence of virtual reality soccer game on walking performance in robotic assisted gait training for children. J Neuroeng Rehabil. 2010 Apr 22;7:15. doi: 10.1186/1743-0003-7-15. PubMed 20412572 ↗
  • Eftekhar-Sadat B, Azizi R, Aliasgharzadeh A, Toopchizadeh V, Ghojazadeh M. Effect of balance training with Biodex Stability System on balance in diabetic neuropathy. Ther Adv Endocrinol Metab. 2015 Oct;6(5):233-40. doi: 10.1177/2042018815595566. PubMed 26445646 ↗
  • Bax M, Goldstein M, Rosenbaum P, Leviton A, Paneth N, Dan B, Jacobsson B, Damiano D; Executive Committee for the Definition of Cerebral Palsy. Proposed definition and classification of cerebral palsy, April 2005. Dev Med Child Neurol. 2005 Aug;47(8):571-6. doi: 10.1017/s001216220500112x. PubMed 16108461 ↗
  • Baker R. Gait analysis methods in rehabilitation. J Neuroeng Rehabil. 2006 Mar 2;3:4. doi: 10.1186/1743-0003-3-4. PubMed 16512912 ↗
  • Cano-Manas MJ, Collado-Vazquez S, Rodriguez Hernandez J, Munoz Villena AJ, Cano-de-la-Cuerda R. Effects of Video-Game Based Therapy on Balance, Postural Control, Functionality, and Quality of Life of Patients with Subacute Stroke: A Randomized Controlled Trial. J Healthc Eng. 2020 Feb 13;2020:5480315. doi: 10.1155/2020/5480315. eCollection 2020. PubMed 32148744 ↗
  • Zhang B, Li D, Liu Y, Wang J, Xiao Q. Virtual reality for limb motor function, balance, gait, cognition and daily function of stroke patients: A systematic review and meta-analysis. J Adv Nurs. 2021 Aug;77(8):3255-3273. doi: 10.1111/jan.14800. Epub 2021 Mar 6. PubMed 33675076 ↗
  • Yatar GI, Yildirim SA. Wii Fit balance training or progressive balance training in patients with chronic stroke: a randomised controlled trial. J Phys Ther Sci. 2015 Apr;27(4):1145-51. doi: 10.1589/jpts.27.1145. Epub 2015 Apr 30. PubMed 25995576 ↗

Individual participant data

Plan to share: No

09

Updates

1 registry update since Sep 25, 2026
Registered
First appeared on the registry. No changes since
Oct 20, 2026
Show all 1 update
  1. Oct 20, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07884552
Lead sponsor
Amira Mahmoud Abdelkader Mohamed
Responsible party
Amira Mahmoud Abdelkader Mohamed (Pediatric physical therapist, Cairo University) — Sponsor-investigator
First posted
Oct 20, 2026
Start date
Oct 1, 2026
Primary completion
Dec 1, 2026 (estimated)
Completion
Feb 1, 2027 (estimated)
Last update
Oct 20, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

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