An interventional study of Left Bundle Branch Pacing in Left Bundle Branch Area Pacing, sponsored by Assiut University. Not yet recruiting. Open to participants aged 5 Years to 18 Years. Per ClinicalTrials.gov, last updated 2026-10-20.
Sponsored by Assiut University · Not applicable, Interventional, and Other
Assiut University is the lead sponsor of 5,050 studies on the registry; 2,174 are open to participants now.
Of its 14 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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The study will include patients fulfilling our inclusion criteria.
Inclusion Criteria:
Exclusion Criteria:
All patients will be subjected to:
A. Full history taking: including age, sex, history of DM, HTN, history of CHD or any previous cardiac intervention, symptoms of heart failure, dizziness or syncope and history of any previous arrhythmia.
B. Full Physical examination:
D. Standard 12 lead ECG. E. Echocardiography (TTE): For cardiac dimensions (IVS thickness, right side dimensions, left ventricular end- systolic and diastolic diameters), LV systolic function, degree of tricuspid regurgitation if present and any other structural abnormality detected.
F. LBBAP implantation technique:
-All patients will undergo implantation of permanent pacemaker either single or dual chamber under fluoroscopic guidance according the EHRA procedural recommendations.
G. Intraprocedural 3D-TEE during implantation:
- 3D-TEE will facilitate accurate lead positioning through direct visualization of the interventricular septum then the investigators will measure interventricular septum (IVS) length, the angle of lead with the IVS, depth of lead in IVS (the distance from lead tip to the RV subendocardial region), the distance from lead tip to the LV subendocardial region, the distance from the lead tip to tricuspid valve annulus and the distance from the lead tip to RV apex.
H. Electrocardiographic features measured during lead implantation:
I. Follow up of the cases:
After one week and then after 3months by:
1. Pediatric patients aged \<18years old. 2. Case who have Congenital complete atrioventricular block, atrioventricular block as a complication after heart surgery, and symptomatic bradycardia . 3. Indications for permanent pacemaker implantation followed contemporary guideline-based recommendations. 4. Pediatric patients had previous right ventricular lead implantation and deterioration of LV systolic function.
Procedure: Left Bundle Branch Pacing
Implantation of permanent pacemaker either single or dual chamber under fluoroscopic guidance according the EHRA procedural recommendations with add value or 3D-TEE in the implantation procedure.
The percentage of success of LBBAP procedure with the guidance of intraprocedural 3D-TEE.
The investigators will reach the accurate site of the lead implantation in interventricular septum to pace the left bundle branch by the accurate imaging tool (intraprocedural 3D-TEE).
Time frame: half to one hour for each case implantation.
The rate 'percent' of the lead related complications during follow up of the cases after implantation.
The participants follow up will be after one week and then after three months to detect the complications by the measurement tool (change in baseline programming pacing threshold in volt).
Time frame: one week to three months
Assessment of the lead site inside the interventricular septum for the rate 'percent' of lead displacement complications during follow up.
The measurement tool is transthoracic echocardiography for measurement the lead site in mm inside the interventricular septum and any change in shape of electrocardiogram waves.
Time frame: one week to three months
No study locations are listed for this record.
Plan to share: Yes
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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