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CompletedNCT07882511Updated Oct 20, 2026

Efficacy and Safety of Minimally Invasive Suprachoroidal Drainage

An observational study in Neovascular Glaucoma, sponsored by Zhongnan Hospital. Completed at 1 site in China. Open to participants aged 18 Years to 90 Years. Per ClinicalTrials.gov, last updated 2026-10-20.

Sponsored by Zhongnan Hospital · Observational

Updated Oct 20, 2026Newly registeredGo to Updates ↓
Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
50
Ages
18 Years to 90 Years
Sex
All
01

Study summary

This study primarily involved a retrospective analysis of clinical and follow-up data from patients with advanced neovascular glaucoma who underwent minimally invasive suprachoroidal drainage surgery at the Department of Ophthalmology, Zhongnan Hospital of Wuhan University, to evaluate the safety and efficacy of this procedure in patients with advanced neovascular glaucoma.

Read the detailed description

The purpose of this study is to conduct a retrospective analysis of clinical objective indicators-including intraocular pressure, medication use, and pain scores-as well as follow-up outcomes in patients with advanced neovascular glaucoma who underwent minimally invasive suprachoroidal drainage surgery. The study aims to evaluate the safety and efficacy of this procedure for advanced neovascular glaucoma. Additionally, it will conduct a retrospective analysis of clinical data from patients with advanced neovascular glaucoma to identify their clinical characteristics.

02

Conditions studied

  • Neovascular Glaucoma

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03

In context

Glaucoma, Neovascular

37 studies on the registry are indexed under Glaucoma, Neovascular; 5 are open to participants now.

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Lead sponsor

Zhongnan Hospital is the lead sponsor of 105 studies on the registry; 48 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 90 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

A group of patients with advanced neovascular glaucoma (approximately 50 individuals) who underwent minimally invasive suprachoroidal drainage surgery at the Department of Ophthalmology, Zhongnan Hospital of Wuhan University, between July 2024 and May 2026

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Inclusion criteria

  • Patients who met the diagnostic criteria for advanced NVG.

Exclusion criteria

Exclusion Criteria:

  • Patients with incomplete clinical data and information.
  • Severe systemic diseases (such as chronic renal failure requiring dialysis, severe neurological diseases, immune diseases), pregnancy or lactation.
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
50 participants (actual)
Patient registry
No

Groups and cohorts

  • NVG group
06

What researchers measure

Primary outcomes

  1. intraocular pressure

    intraocular pressure(IOP)

    Time frame: Pre-operative, post-operative follow-up at 1 month, 3 months, 6 months.

  2. visual acuity

    best-corrected visual acuity (BCVA)

    Time frame: Pre-operative, post-operative follow-up at 1 month, 3 months, 6 months.

  3. Number of anti-glaucoma medications

    number of anti-glaucoma medications

    Time frame: Time Frame: Pre-operative, post-operative follow-up at 1 month, 3 months, 6 months.

Secondary outcomes

  1. complications

    Complications that may arise during and after surgery, such as haemorrhage into the anterior chamber, vitreous haemorrhage, corneal endothelial decompensation and ocular atrophy, etc.

    Time frame: Pre-operative, post-operative follow-up at 1 month, 3 months, 6 months.

  2. NRS

    The Numerical Rating Scale (NRS) is a unidimensional pain scale consisting of 11 numbers ranging from 0 to 10, which are used to describe the intensity of pain in incremental steps.

    Time frame: Pre-operative (pain scores at baseline) and post-operative (pain scores at the time of the patient's discharge, ranging from 3 to 7 days postoperatively)

07

Study locations

1 site
  • Zhongnan Hospital of Wuhan University
    Wuhan, Hubei 430060, China
08

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from Jul 2024 to primary completion in Apr 2026, 21 months.

How these figures are worked out, and which studies are left out of them.

Registered
Sep 2, 2026
First posted
Oct 20, 2026
StartActual
Jul 1, 2024
Primary completionActual
Apr 30, 2026
CompletionActual
Apr 30, 2026
Last update
Oct 20, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Oct 20, 2026
Show all 1 update
  1. Oct 20, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

09

Registry details

Key details

Study ID
NCT07882511
Lead sponsor
Zhongnan Hospital
Responsible party
Sponsor
First posted
Oct 20, 2026
Start date
Jul 1, 2024
Primary completion
Apr 30, 2026
Completion
Apr 30, 2026
Last update
Oct 20, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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