ClinicalTrials.gg
Active, not recruitingNCT07879742Bio-ACEUpdated Oct 19, 2026

Biological Age Study of Chicken Essence

An interventional study of Essence of Chicken (BEC) and Placebo in Biological Age and Essence of Chicken, sponsored by Brand's Suntory Asia. Active, not recruiting at 7 sites in Thailand. Open to participants aged 35 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-10-19.

Sponsored by Brand's Suntory Asia · Not applicable, Interventional, and Other

Updated Oct 19, 2026Newly registeredGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
262
Allocation
Randomized
Ages
35 Years to 45 Years
Sex
All
01

Study summary

The goal of this clinical trial is to evaluate the effects of BRAND'S Essence of Chicken (BEC) on biological age. Biological age will be measured using epigenetic clocks [DunedinPACE (primary), GrimAge, PhenoAge, etc] and other relevant tools.

Participants will take BEC or a placebo every day for 1 year. Biological age measures will be taken at baseline and after 1 year.

02

Conditions studied

  • Biological Age
  • Essence of Chicken
03

In context

Lead sponsor

Brand's Suntory Asia is the lead sponsor of 3 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
35 Years to 45 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. Healthy participants aged 35 to 45 years
  2. Must not participate in other clinical studies

Exclusion criteria

Exclusion Criteria

  1. A history of allergy to Essence of Chicken or any ingredients of product (IP)
  2. An evidence or history of diseases within the last 5 years
  3. ≥ 30 kg/m2
  4. Any laboratory test or clinical signs and symptoms greater than grade 1 of grading.
  5. Has clinically significant abnormalities in laboratory test results under investigator judgement.
  6. Has other severe acute or chronic medical or psychiatric conditions or laboratory abnormality
  7. Concurrent pharmacological treatments or use of cannabis-containing products.
  8. Any recent drastic changes in lifestyle (diet, exercise, smoking pattern, sleep habits and supplement intake) in the last 4 weeks.
  9. Judgment by the investigator that the participant should not participate in the study, for instance if the participant is unlikely to comply with all study procedures or if the participant is unlikely to be in good health throughout the study.
  10. Regular consumption of any Essence of Chicken, defined as > 2 bottles a week of consumption in the past 6 months.
  11. Heavy smokers consume 7 or more standard packs per week.
  12. Heavy drinkers consuming 15 or more standard drinks per week.
  13. Individuals with poor sleep habits (i.e. allocate less than 4 hours of sleep per night)
  14. Women who are pregnant or lactating or has a plan to become pregnant during study period.
  15. Woman who has menopausal status, underwent oophorectomy and has to receive hormonal replacement therapy.
  16. Have undergone surgery within 3 weeks prior to screening
  17. Current enrolment in another interventional study or refusal to refrain from participating in another interventional study during the study period.
Terms in these criteria, in plain language(4)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Investigational drug or device

A drug or device being studied in a clinical trial.

It may be new, or already approved and being studied for another use, dose or form. Criteria often leave out people who took part in another study of one within a recent period, commonly 30 days or five half-lives.

Clinically significant

Judged by the study doctor to matter for your health or for the study. It is a doctor’s decision, so ask the study team if you are unsure whether something counts.

BMI (body mass index)

Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.

What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.

CTCAE grade

The US National Cancer Institute’s scale of how severe an adverse event is — any unwanted medical event during a study, such as a symptom, an illness or an abnormal test result, whether or not a treatment caused it. Whether it did is judged separately.

1
Mild.
2
Moderate.
3
Severe.
4
Life-threatening.
5
Death due to the event.

“Side effects of earlier treatment resolved to grade 1 or less” means they have settled to mild or gone.

05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Quadruple (Participant, Care provider, Investigator, Outcomes assessor)
Enrollment
262 participants (actual)

Study arms

  • Placebo comparator
    Placebo

    70 ml liquid

    Dietary Supplement: Placebo

  • Experimental
    Essence of chicken (BEC)

    70 ml liquid

    Dietary Supplement: Essence of Chicken (BEC)

Interventions

  • Dietary supplementEssence of Chicken (BEC)

    Eligible participants will be randomised to receive BEC or placebo for 1 year

  • Dietary supplementPlacebo

    Eligible participants will be randomised to receive BEC or placebo for 1 year

06

What researchers measure

Primary outcomes

  1. Change in biological age (epigenetic age)

    DunedinPACE epigenetic clock

    Time frame: From baseline to end of intervention (1 year)

Secondary outcomes

  1. Change in biological age (epigenetic age)

    GrimAge epigenetic clock

    Time frame: From baseline to end of intervention (1 year)

  2. Change in biological age (epigenetic age)

    PhenoAge epigenetic clock

    Time frame: From baseline to end of intervention (1 year)

  3. Change in biological age (epigenetic age)

    Horvath and Hannum epigenetic clock

    Time frame: From baseline to end of intervention (1 year)

  4. Change in biological age (epigenetic age)

    SYMPHONYAge (SystemsAge of each organ system)

    Time frame: From baseline to end of intervention (1 year)

  5. Change in biological age (epigenetic age)

    OMICm Age

    Time frame: From baseline to end of intervention (1 year)

  6. Change in biological age

    Immune Cell Deconvolution

    Time frame: From baseline to end of intervention (1 year)

  7. Change in biological age

    Telomere

    Time frame: From baseline to end of intervention (1 year)

  8. Change in biological age based on composite biomarker approach

    Published algorithm derived from clinical blood chemistries

    Time frame: From baseline to end of intervention (1 year)

  9. Epigenome-wide association study (EWAS)

    Time frame: From baseline to end of intervention (1 year)

  10. Change in quality of life (RAND-36)

    RAND 36-Item Health Survey (RAND-36). Scores range from 0 to 100. Higher values mean a more favorable health state.

    Time frame: From baseline to end of intervention (1 year)

  11. Change in self-reported cognitive function

    PROMIS Cognitive Function - Abilities-Short Form 8a. Raw scores range from 8 to 40. Raw Score will be converted to a standardized PROMIS T-score. Higher T-scores represent better cognitive function/abilities

    Time frame: From baseline to end of intervention (1 year)

Other outcomes

  1. Change in blood inflammatory marker level

    C Reactive Protein (hsCRP)

    Time frame: From baseline to end of intervention (1 year)

  2. Change in blood inflammatory marker level

    Erythrocyte Sedimentation Rate (ESR)

    Time frame: From baseline to end of intervention (1 year)

  3. Change in blood inflammatory marker level

    Interleukin 6 (IL 6)

    Time frame: From baseline to end of intervention (1 year)

  4. Change in blood oxidative marker level

    Malondialdehyde (MDA)

    Time frame: From baseline to end of intervention (1 year)

07

Study locations

7 sites
  • Faculty of Pharmaceutical Sciences, Chulalongkorn University
    Bangkok, Thailand
  • Faculty of Pharmacy, Mahidol University
    Bangkok, Thailand
  • Faculty of Pharmacy, Chiang Mai University
    Chiang Mai, Thailand
  • Faculty of Pharmaceutical Sciences, Khon Kaen University
    Khon Kaen, Thailand
  • Faculty of Pharmacy, Srinakharinwirot University
    Nakhon Nayok, Thailand
  • Faculty of Pharmacy, Silpakorn University
    Nakhon Pathom, Thailand
  • Faculty of Pharmaceutical Sciences, Prince of Songkla University
    Songkhla, Thailand
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Started Sep 2025 (actual). Primary completion is estimated for Jan 2027, 16 months after the start.

How these figures are worked out, and which studies are left out of them.

Registered
Sep 10, 2025
First posted
Oct 19, 2026
StartActual
Sep 24, 2025
Primary completionEst.
Jan 2027
CompletionEst.
Apr 2027
Last update
Oct 19, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Oct 19, 2026
Show all 1 update
  1. Oct 19, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07879742
Lead sponsor
Brand's Suntory Asia
Responsible party
Sponsor
First posted
Oct 19, 2026
Start date
Sep 24, 2025
Primary completion
Jan 2027 (estimated)
Completion
Apr 2027 (estimated)
Last update
Oct 19, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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Discussion

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