An observational study in Lumbar Radicular Pain and Artifical Intelligence, sponsored by Marmara University. Not yet recruiting. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2026-10-15.
Sponsored by Marmara University · Observational
This study aims to prospectively evaluate the accuracy of artificial intelligence (AI) in predicting fluoroscopic C-arm oblique and craniocaudal angles from pre-procedural lumbar magnetic resonance (MR) images for lumbar transforaminal epidural steroid injections (TFESI). The AI predictions will be compared to the final reference C-arm angles determined by an experienced operator during the procedure.
Lumbar transforaminal epidural steroid injection (TFESI) is an interventional pain treatment commonly used for lumbar radicular pain. It requires appropriate fluoroscopic visualization of the targeted nerve root and neural foramen to safely advance the needle. During the procedure, the fluoroscopic C-arm must be positioned at appropriate oblique and craniocaudal angles to optimally visualize the target anatomical structures. The required C-arm angles vary among patients due to individual anatomical features such as vertebra and pedicle morphology, facet joint structure, vertebral rotation, and lumbar lordosis. Currently, these angles are determined based on operator experience and sequential fluoroscopic images, often requiring multiple repositioning attempts and additional radiation exposure. Since many patients undergo lumbar MR imaging prior to TFESI, utilizing anatomical information from these existing images could help predict patient-specific initial C-arm angles. This study will use an AI-based system (ChatGPT) to evaluate standard T2-weighted lumbar MR images and predict the optimal oblique and craniocaudal C-arm angles. The operating physician will be blinded to the AI predictions and will determine the C-arm positioning based solely on their clinical evaluation. The study aims to evaluate whether AI can accurately predict these angles and to determine if prediction accuracy varies based on the target lumbar level and patient characteristics.
Marmara University is the lead sponsor of 590 studies on the registry; 135 are open to participants now.
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dult patients scheduled for unilateral or bilateral, single or multi-level TFESI due to lumbar radicular pain as part of routine clinical practice.
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Exclusion Criteria:
AI-based evaluation of pre-procedural T2-weighted lumbar MR images to predict optimal fluoroscopic C-arm angles (oblique and craniocaudal)
The absolute error (in degrees) between the AI-predicted oblique and craniocaudal C-arm angles and the reference angles determined by the operator during the procedure
The absolute error (in degrees) between the AI-predicted oblique and craniocaudal C-arm angles and the reference angles determined by the operator during the procedure
Time frame: Baseline
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From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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