ClinicalTrials.gg
Not yet recruitingNCT07873918Updated Oct 14, 2026

Mortality and Predictors of In-hospital Mortality Among Geriatric Patients With Hip Fracture

An observational study in Hip Fractures and In-hospital Mortality, sponsored by Assiut University. Not yet recruiting. Open to participants aged 65 Months and older. Per ClinicalTrials.gov, last updated 2026-10-14.

Sponsored by Assiut University · Observational

Updated Oct 14, 2026Newly registeredGo to Updates ↓
Study type
Observational
Model
Cohort
Time perspective
Other
Enrollment
141
Ages
65 Months and older
Sex
All
01

Study summary

To assess the incidence of in-hospital mortality among geriatric patients with hip fractures and to identify its potential predictors

Read the detailed description

Population ageing is a major global demographic transition. In 2020, approximately 1 billion people worldwide were aged 60 years or older. This number is projected to increase to 1.4 billion by 2030, when approximately one in six people globally will be aged ≥60 years. In Egypt, approximately 9.77 million people are aged ≥60 years, representing nearly 10% of the total population.

Hip fractures are a major health problem among older adults, causing substantial morbidity, functional decline, loss of independence, prolonged hospitalization, and increased mortality .

Falls are the predominant mechanism of hip fracture in older adults, with more than 90% of fractures attributable to falls, . This emphasizes the importance of underlying skeletal fragility in addition to fall characteristic .

Osteoporosis is a major contributor to skeletal fragility and susceptibility to hip fracture after low-energy trauma . BMI also influences both fracture risk and prognosis; low BMI is associated with greater fracture susceptibility, while underweight patients have higher mortality after hip fracture .

Comorbidities may further increase fracture susceptibility and affect outcomes. Diabetes, hypertension, cardiovascular disease, and chronic kidney disease have been associated with increased fracture risk among older adults .

Hip fractures are associated with considerable in-hospital mortality, while outcomes vary according to patient characteristics, comorbidity burden, and clinical management. However, prospective studies identifying independent predictors of in-hospital mortality, particularly in Egyptian geriatric populations, remain limited .

Therefore, this study aims to determine the incidence of in-hospital mortality and identify its predictors among geriatric patients with hip fractures

02

Conditions studied

  • Hip Fractures
  • In-hospital Mortality

Browse trials for

03

In context

Hip Fractures

848 studies on the registry are indexed under Hip Fractures; 160 are open to participants now.

This study's planned enrollment of 141 is close to the median of 142 across 277 observational studies indexed under Hip Fractures.

Browse Hip Fractures studies →

Lead sponsor

Assiut University is the lead sponsor of 5,050 studies on the registry; 2,174 are open to participants now.

Of its 14 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
65 Months and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Patients aged ≥65 years diagnosed with a hip fracture and admitted to the Trauma Unit during the study period.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • patients aged ≥65 years.
  • Patients diagnosed with a hip fracture and admitted to the Trauma Unit during the study period.
  • Patients who provide informed consent to participate in the study, either personally or through their caregiver when appropriate.

Exclusion criteria

Exclusion Criteria:

  • patients younger than 65 years.
  • Peri-prosthetic hip fractures.
  • Pathological hip fractures.
05

Study design

Observational model
Cohort
Time perspective
Other
Enrollment
141 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Incidence of In-Hospital Mortality

    The study participants will be followed from hospital arrival and initial diagnosis of hip fracture, through their subsequent surgical management, and throughout the postoperative period until hospital discharge or in-hospital death, whichever occurs first

    Time frame: About 1 month from hospital arrival till in-hospital death or discharge

07

Study locations

No study locations are listed for this record.

08

References and documents

Publications

  • Van Heghe A, Mordant G, Dupont J, Dejaeger M, Laurent MR, Gielen E. Effects of Orthogeriatric Care Models on Outcomes of Hip Fracture Patients: A Systematic Review and Meta-Analysis. Calcif Tissue Int. 2022 Feb;110(2):162-184. doi: 10.1007/s00223-021-00913-5. Epub 2021 Sep 30. PubMed 34591127 ↗
  • Abdelnasser MK, Khalifa AA, Amir KG, Hassan MA, Eisa AA, El-Adly WY, Ibrahim AK, Farouk OA, Abubeih HA. Mortality incidence and its determinants after fragility hip fractures: a prospective cohort study from an Egyptian level one trauma center. Afr Health Sci. 2021 Jun;21(2):806-816. doi: 10.4314/ahs.v21i2.41. PubMed 34795739 ↗
  • Covino M, Vitiello R, De Matteis G, Bonadia N, Piccioni A, Carbone L, Zaccaria R, Cauteruccio M, Ojetti V, Franceschi F. Hip Fracture Risk in Elderly With Non-End-Stage Chronic Kidney Disease: A Fall Related Analysis. Am J Med Sci. 2022 Jan;363(1):48-54. doi: 10.1016/j.amjms.2021.06.015. Epub 2021 Jul 10. PubMed 34256032 ↗
  • Gerber Y, Melton LJ 3rd, McNallan SM, Jiang R, Weston SA, Roger VL. Cardiovascular and noncardiovascular disease associations with hip fractures. Am J Med. 2013 Feb;126(2):169.e19-26. doi: 10.1016/j.amjmed.2012.06.032. PubMed 23331448 ↗
  • Zhu YY, Wei HF, Li S, Li L, Wang P, Pan HF. Associations of chronic disease status and the risk of new-onset hip or femoral fractures in older population. J Orthop. 2025 May 27;68:149-156. doi: 10.1016/j.jor.2025.05.049. eCollection 2025 Oct. PubMed 40519338 ↗
  • Wallander M, Axelsson KF, Nilsson AG, Lundh D, Lorentzon M. Type 2 Diabetes and Risk of Hip Fractures and Non-Skeletal Fall Injuries in the Elderly: A Study From the Fractures and Fall Injuries in the Elderly Cohort (FRAILCO). J Bone Miner Res. 2017 Mar;32(3):449-460. doi: 10.1002/jbmr.3002. Epub 2016 Oct 31. PubMed 27664946 ↗
  • Park HY, Han K, Kim Y, Kim YH, Sur YJ. The risk of hip fractures in individuals over 50 years old with prediabetes and type 2 diabetes - A longitudinal nationwide population-based study. Bone. 2021 Jan;142:115691. doi: 10.1016/j.bone.2020.115691. Epub 2020 Oct 15. PubMed 33069920 ↗
  • Modig K, Erdefelt A, Mellner C, Cederholm T, Talback M, Hedstrom M. "Obesity Paradox" Holds True for Patients with Hip Fracture: A Registry-Based Cohort Study. J Bone Joint Surg Am. 2019 May 15;101(10):888-895. doi: 10.2106/JBJS.18.01249. PubMed 31094980 ↗
  • Park CH, Lee SH, Lee R, Kim DY, Cho MR, Song SK. Effects of body mass index on mortality in elderly patients with hip fractures. Medicine (Baltimore). 2024 Aug 2;103(31):e39157. doi: 10.1097/MD.0000000000039157. PubMed 39093801 ↗
  • Kim SH, Yi SW, Yi JJ, Kim YM, Won YJ. Association Between Body Mass Index and the Risk of Hip Fracture by Sex and Age: A Prospective Cohort Study. J Bone Miner Res. 2018 Sep;33(9):1603-1611. doi: 10.1002/jbmr.3464. Epub 2018 Jun 15. PubMed 29750839 ↗
  • Ruggiero C, Baroni M, Xenos D, Parretti L, Macchione IG, Bubba V, Laudisio A, Pedone C, Ferracci M, Magierski R, Boccardi V, Antonelli-Incalzi R, Mecocci P. Dementia, osteoporosis and fragility fractures: Intricate epidemiological relationships, plausible biological connections, and twisted clinical practices. Ageing Res Rev. 2024 Jan;93:102130. doi: 10.1016/j.arr.2023.102130. Epub 2023 Nov 27. PubMed 38030092 ↗
  • Yang Y, Komisar V, Shishov N, Lo B, Korall AM, Feldman F, Robinovitch SN. The Effect of Fall Biomechanics on Risk for Hip Fracture in Older Adults: A Cohort Study of Video-Captured Falls in Long-Term Care. J Bone Miner Res. 2020 Oct;35(10):1914-1922. doi: 10.1002/jbmr.4048. Epub 2020 Jul 6. PubMed 32402136 ↗
  • 3. Reddy BA, Sreenath M, Macherla VG, et al. Epidemiological trends and risk factors of hip fractures in elderly patients: a retrospective study. Eur J Cardiovasc Med. 2025;15(10):200-205.
  • 1. World Health Organization. Ageing and health. 2025

Individual participant data

Plan to share: Undecided

09

Updates

1 registry update since Sep 25, 2026
Registered
First appeared on the registry. No changes since
Oct 14, 2026
Show all 1 update
  1. Oct 14, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07873918
Lead sponsor
Assiut University
Responsible party
Moetaz Mahmoud Attya (Resident doctor, Assiut University) — Principal investigator
First posted
Oct 14, 2026
Start date
Mar 2027 (estimated)
Primary completion
Apr 2028 (estimated)
Completion
Apr 2028 (estimated)
Last update
Oct 14, 2026

Study contacts

moetaz Mahmoud Attya, Master
Contact
moetazmahmoud229@gmail.com
+201095352336

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion